{"title":"饲喂酸奶或乳糖对n -甲基- n '-硝基- n -亚硝基胍诱导大鼠胃肿瘤发生的抑制作用","authors":"Y. Morishita, K. Shiromizu","doi":"10.12938/BIFIDUS1982.9.2_135","DOIUrl":null,"url":null,"abstract":"After the previous administration with N-methyl-N'-nitroN-nitrosoguanidine in drinking water, Wistar rats were fed 25 g/day of yoghurt on 4 days every week or a 20%-lactose-containing purified diet, and the incidence of gastrointestinal tumors in them was compared with that in their counterparts. The yoghurt-fed rats showed a significantly lower incidence of gastric tumors (50%) than the counterpart group (89%). Dietary lactose considerably suppressed the incidence of gastric tumors (10%) compared to the control diet (44%) . These data support the epidemiological view that milk and milk products are protective against human gastric cancer.","PeriodicalId":414713,"journal":{"name":"Bifidobacteria and Microflora","volume":"22 1","pages":"0"},"PeriodicalIF":0.0000,"publicationDate":"1900-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":"8","resultStr":"{\"title\":\"Suppressive Effect of Feeding Yoghurt or Lactose on N-Methyl-N'-Nitro-N-Nitrosoguanidine-Induced Gastric Tumorigenesis in Rats\",\"authors\":\"Y. Morishita, K. Shiromizu\",\"doi\":\"10.12938/BIFIDUS1982.9.2_135\",\"DOIUrl\":null,\"url\":null,\"abstract\":\"After the previous administration with N-methyl-N'-nitroN-nitrosoguanidine in drinking water, Wistar rats were fed 25 g/day of yoghurt on 4 days every week or a 20%-lactose-containing purified diet, and the incidence of gastrointestinal tumors in them was compared with that in their counterparts. The yoghurt-fed rats showed a significantly lower incidence of gastric tumors (50%) than the counterpart group (89%). Dietary lactose considerably suppressed the incidence of gastric tumors (10%) compared to the control diet (44%) . These data support the epidemiological view that milk and milk products are protective against human gastric cancer.\",\"PeriodicalId\":414713,\"journal\":{\"name\":\"Bifidobacteria and Microflora\",\"volume\":\"22 1\",\"pages\":\"0\"},\"PeriodicalIF\":0.0000,\"publicationDate\":\"1900-01-01\",\"publicationTypes\":\"Journal Article\",\"fieldsOfStudy\":null,\"isOpenAccess\":false,\"openAccessPdf\":\"\",\"citationCount\":\"8\",\"resultStr\":null,\"platform\":\"Semanticscholar\",\"paperid\":null,\"PeriodicalName\":\"Bifidobacteria and Microflora\",\"FirstCategoryId\":\"1085\",\"ListUrlMain\":\"https://doi.org/10.12938/BIFIDUS1982.9.2_135\",\"RegionNum\":0,\"RegionCategory\":null,\"ArticlePicture\":[],\"TitleCN\":null,\"AbstractTextCN\":null,\"PMCID\":null,\"EPubDate\":\"\",\"PubModel\":\"\",\"JCR\":\"\",\"JCRName\":\"\",\"Score\":null,\"Total\":0}","platform":"Semanticscholar","paperid":null,"PeriodicalName":"Bifidobacteria and Microflora","FirstCategoryId":"1085","ListUrlMain":"https://doi.org/10.12938/BIFIDUS1982.9.2_135","RegionNum":0,"RegionCategory":null,"ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"","PubModel":"","JCR":"","JCRName":"","Score":null,"Total":0}
Suppressive Effect of Feeding Yoghurt or Lactose on N-Methyl-N'-Nitro-N-Nitrosoguanidine-Induced Gastric Tumorigenesis in Rats
After the previous administration with N-methyl-N'-nitroN-nitrosoguanidine in drinking water, Wistar rats were fed 25 g/day of yoghurt on 4 days every week or a 20%-lactose-containing purified diet, and the incidence of gastrointestinal tumors in them was compared with that in their counterparts. The yoghurt-fed rats showed a significantly lower incidence of gastric tumors (50%) than the counterpart group (89%). Dietary lactose considerably suppressed the incidence of gastric tumors (10%) compared to the control diet (44%) . These data support the epidemiological view that milk and milk products are protective against human gastric cancer.
求助内容：
应助结果提醒方式：
京公网安备 11010802042870号
