血链球菌罕见血清型与白塞病密切相关

E. Isogai, S. Ohno, K. Takeshi, K. Yoshikawa, T. Tsurumizu, H. Isogai, K. Yokota, S. Kotake, Y. Sasamoto, Hashimoto Takashi, Harumi Shimizu, H. Matsuda, N. Fujii, M. Yamaguchi, K. Oguma
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引用次数: 39

摘要

本文描述了血链球菌在白塞氏病(BD)患者口腔菌群中的作用,并与健康对照组的菌群进行了对比。血链球菌在BD患者菌群中的比例始终高于健康人群和疾病对照组。在BD患者的口腔菌群中,血链球菌的类型并不常见。血链球菌分离株的凝集抗体滴度在BD患者中高于对照组。当血血链球菌抗原用于皮肤反应时,BD患者皮肤红斑明显大于健康对照组。我们认为罕见的血链球菌血清型可能在双相障碍的发病机制中起作用。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
Close Association of Streptococcus sanguis Uncommon Serotypes with Behcet's Disease
This is a description of the role of Streptococcus sanguis in the oral flora of patients with Behcet's disease (BD) in contrast to the flora of healthy controls. The proportion of S. sanguis in the flora of patients with BD was always higher than that of healthy and disease controls. The types of S. sanguis in the oral flora of the BD patients were uncommon ones. Agglutinating antibody titers againstisolated strains of S. sanguis were higher in BD patients than in controls. When S. sanguis antigens were used in skin reaction, the erythema of skin in BD patients was greater than that in healthy controls. It is proposed that uncommon serotypes of S. sanguis may play a role in the pathogenesis of BD.
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