R. Patnayak, A. Jena, N. Rukmangadha, Chowhan Ak, Phaneendra Bv, M. Reddy, G. Sreenivas
{"title":"Reactive Actinomycotictonsillar lesion","authors":"R. Patnayak, A. Jena, N. Rukmangadha, Chowhan Ak, Phaneendra Bv, M. Reddy, G. Sreenivas","doi":"10.15380/2277-5706.JCSR.12.060","DOIUrl":"https://doi.org/10.15380/2277-5706.JCSR.12.060","url":null,"abstract":"Actinomycosis, because of its varied presentation mimics many other common diseases. We report the rare occurrence of reactive actinomycotic tonsillar lesion in a 17-year-old boy. Accurate histopathological diagnosis facilitated early institution of appropriate treatment.","PeriodicalId":405143,"journal":{"name":"The Journal of Clinical and Scientific Research","volume":"173 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"1900-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"131698982","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"A case of leptospirosis with rare atypical presentation as paraparesis","authors":"PVenkata Krishna, Shaik Ahmed, C. R. Kumar","doi":"10.15380/2277-5706.jcsr.13.061","DOIUrl":"https://doi.org/10.15380/2277-5706.jcsr.13.061","url":null,"abstract":"We report a patient presenting with paraparesis with polyneuropathy who later developed haemorrhagic manifestations and multi-organ involvement and seizures. Diagnostic work-up confirmed the diagnosis of leptospirosis. The presentation of paraparesis in combination with Weil’s syndrome is rare. However, the development of haemorrhagic manifestations and seizures after initial presentation of paraparesis has not been reported previously. A high index of suspicion is necessary for initiating appropriate diagnostic work-up as it is a treatable condition.","PeriodicalId":405143,"journal":{"name":"The Journal of Clinical and Scientific Research","volume":"15 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"1900-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"132041610","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
B. G. Kumari, A. Samantaray, Kanati Geeta, P. Durga, Gopinath Ramchandran, Anantha Kiran Kumar, Gudaru Jagadeesh
{"title":"Does addition of metoclopramide to lignocaine confer additional advantage on reducing pain on propofol injection","authors":"B. G. Kumari, A. Samantaray, Kanati Geeta, P. Durga, Gopinath Ramchandran, Anantha Kiran Kumar, Gudaru Jagadeesh","doi":"10.15380/2277-5706.JCSR.13.060","DOIUrl":"https://doi.org/10.15380/2277-5706.JCSR.13.060","url":null,"abstract":"Background: Intravenous injection of lipid emulsion propofol induces a considerable degree of pain and the most preferred treatment suggested is pretreatment with intravenous lignocaine to alleviate such pain. The present study was designed to evaluate whether addition of metoclopramide to lignocaine offers any advantage over lignocaine alone as a pretreatment in prevention of pain following propofol injection. Methods: In this prospective, randomized, double-blind controlled study, 60 patients were randomized to receive either lignocaine (group A) or lignocaine with metoclopramide (group B) intravenously as a pretreatment before injection of propofol. Pain due to injection of propofol was assessed with a four point categorical verbal rating pain scale. The incidence and magnitude of pain was compared between the two groups. Results: There was no statistically significant difference in the perceived intensity of pain between the two groups at different time points after administration of propofol. The incidence of moderate pain was 23.3% in group A and 20% in group B (p = 0.211); 26.7% patients in group A and 43.3% patients in group B had no pain during propofol administration (p = 0.116). Conclusions: Addition of metoclopramide to lignocaine does not have additional advantage over lignocaine alone in alleviating the pain of emulsified propofol injection.","PeriodicalId":405143,"journal":{"name":"The Journal of Clinical and Scientific Research","volume":"65 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"1900-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"114339468","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Retroperitoneal synovial sarcoma presenting as paraneoplastic hypoglycaemia","authors":"Reddy Vv, S. Sarala, Mathai, Madhu, S. Kv","doi":"10.15380/2277-5706.JCSR.13.068","DOIUrl":"https://doi.org/10.15380/2277-5706.JCSR.13.068","url":null,"abstract":"Synovial sarcoma is a well-recognized malignant mesenchymal neoplasm. Primary retroperitoneal synovial sarcoma is extremely rare and has poor prognosis. There are sparse reports in the literature on the secretory synovial sarcomas. In this report, we present the case of a patient with retroperitoneal synovial sarcoma who presented with recurrent attacks of hypoglycaemia.","PeriodicalId":405143,"journal":{"name":"The Journal of Clinical and Scientific Research","volume":"64 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"1900-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"121410221","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
G. Eswar, M. Madhav, G. Anvesh, K. Seshaiah, Ajith Mohammad
{"title":"Left bundle branch block: A rare ECG manifestation of hyperkalemia","authors":"G. Eswar, M. Madhav, G. Anvesh, K. Seshaiah, Ajith Mohammad","doi":"10.15380/2277-5706.jcsr.13.075","DOIUrl":"https://doi.org/10.15380/2277-5706.jcsr.13.075","url":null,"abstract":"A 20-year-old female patient with chronic kidney disease was brought to our emergency medical department with symptoms of pain in chest and abdomen, vomitings. Laboratory testing revealed serum potassium 7.7 mEq/L, serum creatinine 9.1 mg/dL. Electrocardiogram (ECG) showed left bundle branch block (LBBB) pattern with left axis deviation, tall T waves and ST elevation. Among ECG alterations in hyperkalemia, LBBB is rare and is being reported in our","PeriodicalId":405143,"journal":{"name":"The Journal of Clinical and Scientific Research","volume":"4 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"1900-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"131099325","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
B. Suresh, S. Kv, R. Arun, D. Jothibai, T. Bharathi
{"title":"Prevalence of “unexpected antibodies” in the antenatal women attending the Government Maternity Hospital, Tirupati","authors":"B. Suresh, S. Kv, R. Arun, D. Jothibai, T. Bharathi","doi":"10.15380/2277-5706.JCSR.14.041","DOIUrl":"https://doi.org/10.15380/2277-5706.JCSR.14.041","url":null,"abstract":"Background: All antibodies to red cell antigens, other than naturally occurring anti-A and anti-B are considered unexpected. They can be either alloantibodies or auto antibodies. In pregnant women, these antibodies may cross the placenta and cause haemolytic disease of the foetus and newborn (HDFN). Timely detection of such antibodies in antenatal women is essential for early management of HDFN. \u0000Methods: A prospective cross-sectional study was carried out on 2060 multiparous pregnant women attending the Government Maternity Hospital, Tirupati to detect prevalence of unexpected antibodies. The women were grouped and typed for ABO and rhesus (Rh) D antigens by tube method and screened for alloantibodies by column agglutination technology. The medical and detailed obstetric history of these women were reviewed. \u0000Results: The overall prevalence of alloantibodies was 1.1%. There was a statistically significant difference between alloimmunization rates in the Rh D-antigen negative and D-antigen positive women (12.8% versus 0.3%). The antibodies detected in this study were, anti-D (63.8%), anti-D+C (13.7%), anti-C, anti-E, anti-M, anti-Lea, and anti-Leb (4.5% each). Anti-D contributed to 77.3% of total alloimmunization in this study. \u0000Conclusions: In spite of the introduction of prophylactic Rh- immunoglobulin, anti-D (77.3%) is still a common antibody identified in the antenatal women of our region. In developing countries like India, universal antenatal antibody screening, though desirable may not be justified at present as the cost and infrastructure required would be immense. However, it is necessary to impose properly formulated protocols to screen at least the pregnant women with adverse obstetric history.","PeriodicalId":405143,"journal":{"name":"The Journal of Clinical and Scientific Research","volume":"292 1 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"1900-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"114267981","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Tuberculosis of the sella masquerading as pituitary adenoma","authors":"Mascarenhas Jv, S. VageeshAyyar","doi":"10.15380/2277-5706.JCSR.12.050","DOIUrl":"https://doi.org/10.15380/2277-5706.JCSR.12.050","url":null,"abstract":"","PeriodicalId":405143,"journal":{"name":"The Journal of Clinical and Scientific Research","volume":"3 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"1900-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"124441363","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Rising incidence of acute kidney injury – The emerging significance of “pill” burden","authors":"S. Padmanabhan","doi":"10.15380/2277-5706.jcsr.15.070","DOIUrl":"https://doi.org/10.15380/2277-5706.jcsr.15.070","url":null,"abstract":"Acute kidney injury (AKI) is defined as a sudden fall in kidney function (over hours to days) resulting in accumulation of nitrogenous waste products and fluids in the body. It is at times a devastating syndrome with high costs to patients and health care systems.1 Most studies of AKI detection are based on serum creatinine levels with or without urine output measurements. The limitation of serum creatinine as a biomarker of AKI is well understood.2 The quest for novel biomarkers is on. These biomarkers should be able to segregate tissue injury from changes in function. This is one area in AKI where knowledge gap exists. The Risk, Injury, Failure, Loss of Function, End stage renal disease (RIFLE) criteria in 2004,3 Acute Kidney Injury Network (AKIN) criteria in 20074 and Kidney Disease Improving Global Outcomes (KDIGO) criteria in 20125 represent substantial advance in our efforts to standardize the definition of AKI.","PeriodicalId":405143,"journal":{"name":"The Journal of Clinical and Scientific Research","volume":"28 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"1900-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"126872366","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Dysphagia in an elderly male: A rare cause","authors":"DPrabath Kumar, S. Challa, P. Thejeswini","doi":"10.15380/2277-5706.jcsr.15.055","DOIUrl":"https://doi.org/10.15380/2277-5706.jcsr.15.055","url":null,"abstract":"A 65-year-old male patient who was known to have type 2 diabetes mellitus and was receiving treatment for the same for the last 20 years presented with pain and stiffness of neck with limited mobility of cervical spine, and progressive dysphagia of 1 month duration. His glycaemic control was good and he did not have evidence of diabetic nephropathy. Radiograph of the cervical spine showed florid, anterior flowing of bridging osteophytes from C3-C6 vertebra (Figures 1A and 1B) impinging on the oesophagus with preservation of disc spaces. There was no evidence of apophyseal joint degeneration or sacroiliac inflammatory changes. The patient was diagnosed to have diffuse idiopathic skeletal hyperostosis (DISH) as per the classification criteria defined by Resnick and Niwayama.1,2","PeriodicalId":405143,"journal":{"name":"The Journal of Clinical and Scientific Research","volume":"69 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"1900-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"130840247","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}