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Endothelial dysfunction in early stages of chronic kidney disease: a pilot study 慢性肾脏疾病早期内皮功能障碍的初步研究
The Journal of Clinical and Scientific Research Pub Date : 2012-04-01 DOI: 10.15380/2277-5706.JCSR.12.029
N. Sowjanya, A. Bitla, M. Suchitra, S. Kumar, rinivasa Rao Pvln
{"title":"Endothelial dysfunction in early stages of chronic kidney disease: a pilot study","authors":"N. Sowjanya, A. Bitla, M. Suchitra, S. Kumar, rinivasa Rao Pvln","doi":"10.15380/2277-5706.JCSR.12.029","DOIUrl":"https://doi.org/10.15380/2277-5706.JCSR.12.029","url":null,"abstract":"","PeriodicalId":405143,"journal":{"name":"The Journal of Clinical and Scientific Research","volume":"9 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2012-04-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"129920097","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 2
Aetiology and factors affecting outcome in patients admitted to medical intensive care unit with delirium in a tertiary care teaching hospital 某三级教学医院重症监护病房谵妄患者的病因及影响预后的因素
The Journal of Clinical and Scientific Research Pub Date : 1900-01-01 DOI: 10.15380/2277-5706.jcsr.14.033
B. Shivanandh, T. Sudhakar, A. Mohan, P. Reddy, D. Aruna
{"title":"Aetiology and factors affecting outcome in patients admitted to medical intensive care unit with delirium in a tertiary care teaching hospital","authors":"B. Shivanandh, T. Sudhakar, A. Mohan, P. Reddy, D. Aruna","doi":"10.15380/2277-5706.jcsr.14.033","DOIUrl":"https://doi.org/10.15380/2277-5706.jcsr.14.033","url":null,"abstract":"Background: Delirium, a common manifestation in critically ill patients is a strong predictor of prolonged intensive care unit (ICU) stay, higher morbidity and mortality. Methods: One hundred patients admitted to medical ICU (MICU) at our tertiary care teaching hospital with delirium were evaluated using confusion assessment method. Their Simplified Acute Physiology score II (SAPS II) at presentation, socio-demographic details, risk factors for development of delirium were recorded; aetiology and factors affecting outcome were identified. Results: Their mean age was 48.1 ± 16.6 years; there were 63 males. Most of them (87%) belonged to lower socioeconomic status. Infections (65%) followed by intentional poisonings (19%), metabolic causes (10%) and substance abuse (6%) were the important aetiological causes. Hyperactive delirium (48%) was the most common, followed by mixed (27%) and hypoactive delirium (25%). Univariate analysis showed that non-survivors had a significantly higher SAPS II (p<0.001) and a higher burden of chronic kidney disease (p<0.001) compared to survivors. Conclusion: Knowledge of the factors influencing delirium will increase our ability for early detection and prevention of delirium.","PeriodicalId":405143,"journal":{"name":"The Journal of Clinical and Scientific Research","volume":"21 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"1900-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"129267568","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Rhabdomyolysis secondary to diarrhoea induced hypokalemia in a human immunodeficiency virus-seropositive patient 人类免疫缺陷病毒血清阳性患者继发于腹泻引起的低钾血症横纹肌溶解
The Journal of Clinical and Scientific Research Pub Date : 1900-01-01 DOI: 10.15380/2277-5706.JCSR.14.006
K. Swaroopa, M. Krishna, Y. Raju, M. Subbalaxmi, N. Chandra, S. Khan
{"title":"Rhabdomyolysis secondary to diarrhoea induced hypokalemia in a human immunodeficiency virus-seropositive patient","authors":"K. Swaroopa, M. Krishna, Y. Raju, M. Subbalaxmi, N. Chandra, S. Khan","doi":"10.15380/2277-5706.JCSR.14.006","DOIUrl":"https://doi.org/10.15380/2277-5706.JCSR.14.006","url":null,"abstract":"Hypokalemia with rhabdomyolysis caused by diarrhoea is uncommon in human immunodeficiency virus (HIV) infected patients. We report the case of a patient with HIV1 infection who presented with chronic diarrhoea that led to hypokalemia induced rhabdomyolysis and acute kidney injury (AKI). A 32 -year-old man, known to be HIV-1 seropositive who was on treatment with tenofovir, lamivudine, lopinavirand ritonavir, presented to the emergency department with 6 months history of diarrhoea and sudden onset of weakness of all 4 limbs of two days duration. On examination limb power was grade 3/5 with hypotonia and diminished reflexes. Laboratory investigations showed severe hypokalemia, low urinary potassium, normal anion-gap metabolic acidosis, markedly increased creatine kinase and mildly increased serum creatinine. He was diagnosed as having diarrhoea induced hypokalemic myopathy leading to rhabdomyolysis and AKI. With potassium supplements, antiprotozoal treatment and adequate hydration he improved significantly and is on regular follow-up. Patients presenting with hypokalemia should be closely monitored for rhabdomyolysis, because outcome is good with early treatment.","PeriodicalId":405143,"journal":{"name":"The Journal of Clinical and Scientific Research","volume":"289 3","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"1900-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"113972359","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
The Journal of Clinical and Scientific Research: The leap forwards! 临床与科学研究杂志:飞跃!
The Journal of Clinical and Scientific Research Pub Date : 1900-01-01 DOI: 10.4103/JCSR.JCSR_10_18
T. R. Kumar, P. Rao
{"title":"The Journal of Clinical and Scientific Research: The leap forwards!","authors":"T. R. Kumar, P. Rao","doi":"10.4103/JCSR.JCSR_10_18","DOIUrl":"https://doi.org/10.4103/JCSR.JCSR_10_18","url":null,"abstract":"","PeriodicalId":405143,"journal":{"name":"The Journal of Clinical and Scientific Research","volume":"38 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"1900-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"127625033","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Unusual case of accidental kerosene ingestion by an adult 成年人意外摄入煤油的罕见病例
The Journal of Clinical and Scientific Research Pub Date : 1900-01-01 DOI: 10.15380/2277-5706.JCSR.14.040
K. Gowrinath, KVijaya Kissinger
{"title":"Unusual case of accidental kerosene ingestion by an adult","authors":"K. Gowrinath, KVijaya Kissinger","doi":"10.15380/2277-5706.JCSR.14.040","DOIUrl":"https://doi.org/10.15380/2277-5706.JCSR.14.040","url":null,"abstract":"Accidental kerosene ingestion is uncommon in adults. We report the rare case of accidental ingestion of kerosene by a previously healthy 20-year-old woman resulting in left lower lobe pneumonitis with minimal pleural effusion. Pulmonary parenchymal lesions were seen only through computed tomography of the chest. Clinical recovery occurred quickly with supportive treatment but resolution of parenchymal lesions was evident on computed tomography of the chest at six months follow-up.","PeriodicalId":405143,"journal":{"name":"The Journal of Clinical and Scientific Research","volume":"96 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"1900-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"114754511","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Comparison of butorphanol and fentanyl for balanced anaesthesia in patients undergoing laparoscopic surgeries under general anaesthesia:A prospective, randomized and double-blind study 布托啡诺和芬太尼在腹腔镜手术全麻下平衡麻醉的比较:一项前瞻性、随机和双盲研究
The Journal of Clinical and Scientific Research Pub Date : 1900-01-01 DOI: 10.15380/2277-5706.JCSR.12.056
Rao Mh, Satyanarayana V, Srinivas B, Muralidhar A, Samantaray A, Krishna Reddy As, Hemanth N
{"title":"Comparison of butorphanol and fentanyl for balanced anaesthesia in patients undergoing laparoscopic surgeries under general anaesthesia:A prospective, randomized and double-blind study","authors":"Rao Mh, Satyanarayana V, Srinivas B, Muralidhar A, Samantaray A, Krishna Reddy As, Hemanth N","doi":"10.15380/2277-5706.JCSR.12.056","DOIUrl":"https://doi.org/10.15380/2277-5706.JCSR.12.056","url":null,"abstract":"Back ground: Laparoscopic surgeries have advantages like shorter stay and rapid return to normal activities because of small incision and les pain. Pain is an unpleasant sensation in the post-operative period. Methods: Fifty patients of American society Anesthesiologists (ASA) grade I and II, scheduled to undergo laparoscopic surgery, were randomized into butorphanol group (Group B) (n=25) and fentanyl group (Group F) (n=25). Four minutes before induction of anesthesia, Group B received inj. butorphanol 40 μg/Kg intravenously while Group F received Inj. fentanyl 2 μg/kg intravenously. All patients received general anaesthesia with controlled ventilation. Heart rate, systolic blood pressure (SBP), diastolic blood pressure (DBP), end tidal carbon dioxide (ETCO2), and oxygen saturation were monitored at different intervals. Results: The demographic data was comparable in both groups (p<0.05). There was a significant difference between the two groups in pulse rate after 12 minutes after intubation that persisted till the 2nd hour of post-operative period. There was no significant difference in DBP till 9 min after intubation, and then onwards significant changes were noted till 4th hour of post-operative period. Butorphanol provided prolonged analgesia when compared to fentanyl. Conclusions: We conclude that butorphanol is a better alternative to fentanyl for use as analgesic in laparoscopic surgeries because of its ability to produce prolonged analgesia, and less post-operative complications.","PeriodicalId":405143,"journal":{"name":"The Journal of Clinical and Scientific Research","volume":"27 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"1900-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"122357388","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 8
A twist in the diagnosis … and the uterus! A case report of third trimester uterine torsion 诊断有误，还有子宫!妊娠晚期子宫扭转1例
The Journal of Clinical and Scientific Research Pub Date : 1900-01-01 DOI: 10.15380/2277-5706.jcsr.14.049
T. Bharathi, S. Varsha, G. Devi, V. Priya, S. Rao, Y. Israel
{"title":"A twist in the diagnosis … and the uterus! A case report of third trimester uterine torsion","authors":"T. Bharathi, S. Varsha, G. Devi, V. Priya, S. Rao, Y. Israel","doi":"10.15380/2277-5706.jcsr.14.049","DOIUrl":"https://doi.org/10.15380/2277-5706.jcsr.14.049","url":null,"abstract":"We report the case of a 26-year-old lady gravida 5, with a previous Caesarean section who presented with 2 episodes of convulsions, shock and evidence of intrauterine foetal death. She was known to have epilepsy since childhood. Anticipating a scar dehiscence or rupture uterus she was posted for emergency laparotomy under spinal anaesthesia. Intra-operatively, 180o uterine torsion was evident. The uterus was untwisted and a lower segment caesarean section was performed to deliver the dead foetus. As the uterus remained flabby and did not retracted after correction of torsion, subtotal hysterectomy was done. She recovered well after surgery. The present case highlights uterine torsions, a rare but potentially dangerous and unexpected obstetric complication and reiterates the need for a timely intervention for better maternal and foetal outcome.","PeriodicalId":405143,"journal":{"name":"The Journal of Clinical and Scientific Research","volume":"46 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"1900-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"122129426","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 1
Dupuytren’s contractures Dupuytren的挛缩
The Journal of Clinical and Scientific Research Pub Date : 1900-01-01 DOI: 10.15380/2277-5706.JCSR.14.012
S. Siddeswari, S. Manohar, B. Suryanarayana, T. Abhilash, Devender
{"title":"Dupuytren’s contractures","authors":"S. Siddeswari, S. Manohar, B. Suryanarayana, T. Abhilash, Devender","doi":"10.15380/2277-5706.JCSR.14.012","DOIUrl":"https://doi.org/10.15380/2277-5706.JCSR.14.012","url":null,"abstract":"","PeriodicalId":405143,"journal":{"name":"The Journal of Clinical and Scientific Research","volume":"12 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"1900-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"126426025","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Dravet syndrome in a 13-year-old child 13岁儿童的德拉韦特综合征
The Journal of Clinical and Scientific Research Pub Date : 1900-01-01 DOI: 10.15380/2277-5706.JCSR.14.024
B. Vengamma, J. Varadaraja, T. Naveen
{"title":"Dravet syndrome in a 13-year-old child","authors":"B. Vengamma, J. Varadaraja, T. Naveen","doi":"10.15380/2277-5706.JCSR.14.024","DOIUrl":"https://doi.org/10.15380/2277-5706.JCSR.14.024","url":null,"abstract":"Dravet syndrome is a rare genetic epilepsy syndrome of infancy and childhood. It is characterized by occurrence of protracted febrile seizures in a normal infant followed by development of multiple seizure types and psychomotor retardation. Identifying Dravet syndrome is important, as early detection of the condition in a child presenting with febrile seizures will facilitate institution of appropriate management. We describe the rare occurrence of Dravet syndrome in a 13-year-old child who presented with mental retardation and seizures of 12 years duration.","PeriodicalId":405143,"journal":{"name":"The Journal of Clinical and Scientific Research","volume":"1 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"1900-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"126038389","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Squamous cell carcinoma larynx presenting as idiopathic thrombocytopenic Purpura 喉部鳞状细胞癌表现为特发性血小板减少性紫癜
The Journal of Clinical and Scientific Research Pub Date : 1900-01-01 DOI: 10.15380/2277-5706.JCSR.14.021
R. Bekur, R. Acharya, L. Dias, K. Pai, S. Belurkar
{"title":"Squamous cell carcinoma larynx presenting as idiopathic thrombocytopenic Purpura","authors":"R. Bekur, R. Acharya, L. Dias, K. Pai, S. Belurkar","doi":"10.15380/2277-5706.JCSR.14.021","DOIUrl":"https://doi.org/10.15380/2277-5706.JCSR.14.021","url":null,"abstract":"Association of immune thrombocytpenic purpura with solid malignancy as paraneoplastic manifestation has been reported earlier mainly with lymphoma and breast cancer. We report the case of a patient with squamous cell carcinoma of the larynx presenting with idiopathic thombocytopenic purpura (ITP). A 67-year-old lady presented with multiple ecchymotic patches and petechiae all over the body and bleeding from oral cavity was found to have severe thrombocytopenia diagnosed as ITP with bone marrow evidence of peripheral destruction without infiltration of bone marrow. Five months later she was diagnosed to have squamous cell carcinoma of larynx. Platelet count improved after splenectomy.","PeriodicalId":405143,"journal":{"name":"The Journal of Clinical and Scientific Research","volume":"70 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"1900-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"127125428","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
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