Physics Reports最新文献

{"title":"Network alignment","authors":"Rui Tang ,&nbsp;Ziyun Yong ,&nbsp;Shuyu Jiang ,&nbsp;Xingshu Chen ,&nbsp;Yaofang Liu ,&nbsp;Yi-Cheng Zhang ,&nbsp;Gui-Quan Sun ,&nbsp;Wei Wang","doi":"10.1016/j.physrep.2024.11.006","DOIUrl":"10.1016/j.physrep.2024.11.006","url":null,"abstract":"<div><div>Complex networks are frequently employed to model physical or virtual complex systems. When certain entities exist across multiple systems simultaneously, unveiling their corresponding relationships across the networks becomes crucial. This problem, known as network alignment, holds significant importance. It enhances our understanding of complex system structures and behaviours, facilitates the validation and extension of theoretical physics research about studying complex systems, and fosters diverse practical applications across various fields. However, due to variations in the structure, characteristics, and properties of complex networks across different fields, the study of network alignment is often isolated within each domain, with even the terminologies and concepts lacking uniformity. This review comprehensively summarizes the latest advancements in network alignment research, focusing on analysing network alignment characteristics and progress in various domains such as social network analysis, bioinformatics, computational linguistics and privacy protection. It provides a detailed analysis of various methods’ implementation principles, processes, and performance differences, including structure consistency-based methods, network embedding-based methods, and graph neural network-based (GNN-based) methods. Additionally, the methods for network alignment under different conditions, such as in attributed networks, heterogeneous networks, directed networks, and dynamic networks, are presented. Furthermore, the challenges and the open issues for future studies are also discussed.</div></div>","PeriodicalId":404,"journal":{"name":"Physics Reports","volume":"1107 ","pages":"Pages 1-45"},"PeriodicalIF":23.9,"publicationDate":"2024-12-02","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143161367","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"物理与天体物理","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Remote detection optical magnetometry","authors":"Alexander M. Akulshin ,&nbsp;Dmitry Budker ,&nbsp;Felipe Pedreros Bustos ,&nbsp;Tong Dang ,&nbsp;Emmanuel Klinger ,&nbsp;Simon M. Rochester ,&nbsp;Arne Wickenbrock ,&nbsp;Rui Zhang","doi":"10.1016/j.physrep.2024.11.004","DOIUrl":"10.1016/j.physrep.2024.11.004","url":null,"abstract":"<div><div>Sensitive magnetometers have been applied in a wide range of research fields, including geophysical exploration, bio-magnetic field detection, ultralow-field nuclear magnetic resonance, etc. Commonly, magnetometers are directly placed at the position where the magnetic field is to be measured. However, in some situations, for example in near space or harsh environments, near nuclear reactors or particle accelerators, it is hard to place a magnetometer directly there. If the magnetic field can be detected remotely, i.e., via stand-off detection, this problem can be solved. As optical magnetometers are based on optical readout, they are naturally promising for stand-off detection. We review various approaches to optical stand-off magnetometry proposed and developed over the years, culminating in recent results on measuring magnetic fields in the mesosphere using laser guide stars, magnetometry with mirrorless-lasing readout, and proposals for satellite-assisted interrogation of atmospheric sodium.</div></div>","PeriodicalId":404,"journal":{"name":"Physics Reports","volume":"1106 ","pages":"Pages 1-32"},"PeriodicalIF":23.9,"publicationDate":"2024-11-20","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142698499","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"物理与天体物理","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Lattice Boltzmann simulations for soft flowing matter","authors":"Adriano Tiribocchi ,&nbsp;Mihir Durve ,&nbsp;Marco Lauricella ,&nbsp;Andrea Montessori ,&nbsp;Jean-Michel Tucny ,&nbsp;Sauro Succi","doi":"10.1016/j.physrep.2024.11.002","DOIUrl":"10.1016/j.physrep.2024.11.002","url":null,"abstract":"<div><div>Over the last decade, the Lattice Boltzmann method has found major scope for the simulation of a large spectrum of problems in soft matter, from multiphase and multi-component microfluidic flows, to foams, emulsions, colloidal flows, to name but a few. Crucial to many such applications is the role of supramolecular interactions which occur whenever mesoscale structures, such as bubbles or droplets, come in close contact, say of the order of tens of nanometers. Regardless of their specific physico-chemical origin, such near-contact interactions are vital to preserve the coherence of the mesoscale structures against coalescence phenomena promoted by capillarity and surface tension, hence the need of including them in Lattice Boltzmann schemes. Strictly speaking, this entails a complex multiscale problem, covering about six spatial decades, from centimeters down to tens of nanometers, and almost twice as many in time. Such a multiscale problem can hardly be taken by a single computational method, hence the need for coarse-grained models for the near-contact interactions. In this review, we shall discuss such coarse-grained models and illustrate their application to a variety of soft flowing matter problems, such as soft flowing crystals, strongly confined dense emulsions, flowing hierarchical emulsions, soft granular flows, as well as the transmigration of active droplets across constrictions. Finally, we conclude with a few considerations on future developments in the direction of quantum-nanofluidics, machine learning, and quantum computing for soft flows applications.</div></div>","PeriodicalId":404,"journal":{"name":"Physics Reports","volume":"1105 ","pages":"Pages 1-52"},"PeriodicalIF":23.9,"publicationDate":"2024-11-19","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142699144","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"物理与天体物理","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Interacting topological quantum aspects with light and geometrical functions","authors":"Karyn Le Hur","doi":"10.1016/j.physrep.2024.11.003","DOIUrl":"10.1016/j.physrep.2024.11.003","url":null,"abstract":"<div><div>I review my recent progress and develop a geometrical approach in the quantum with light as a guide, from the vector potential in classical physics, revealing that topological properties can be equivalently measured from the poles of a sphere. The topological state is induced on the Bloch sphere of a spin-1/2 particle from a radial magnetic field related to the physics of Skyrmions. This shows a relation between the global topological response being measured at the poles, the response to a circularly polarized field and the quantum metric. I show how this approach is helpful for the classification of matter with the detection of the global topological invariant at specific points in the Brillouin zone, e.g. the Dirac points, from the responses to electromagnetic waves such as circularly polarized light and from new geometrical functions associated to the quantum metric measuring the quantum Hall and spin Hall conductivities. The <span><math><mi>M</mi></math></span> point associated to the Brillouin zone of the honeycomb lattice also reveals the topological signature. Interactions are included in momentum space within a stochastic variational approach. In a realistic quantum model of interacting spins, this leads to fractional topological entangled aspects with a correspondence between a pair of half invariants and a Einstein–Podolsky–Rosen (EPR) pair or Bell state at one pole. I also formulate a correspondence between fractional topological numbers and resonating valence bond states. This approach gives further insight on the characterization of topological matter linked to superconductivity, protected topological semimetals in two dimensions and on the search of Majorana fermions for topologically protected quantum information. We also address a correspondence with the fractional quantum Hall effect and surface states of three-dimensional topological insulators.</div></div>","PeriodicalId":404,"journal":{"name":"Physics Reports","volume":"1104 ","pages":"Pages 1-42"},"PeriodicalIF":23.9,"publicationDate":"2024-11-16","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142657528","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"物理与天体物理","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Characterising the Higgs boson with ATLAS data from the LHC Run-2","authors":"ATLAS Collaboration","doi":"10.1016/j.physrep.2024.11.001","DOIUrl":"10.1016/j.physrep.2024.11.001","url":null,"abstract":"<div><div>The Higgs boson was discovered by the ATLAS and CMS Collaborations in 2012 using data from Run 1 of the Large Hadron Collider (2010<span><math><mo>−</mo></math></span>2012). In Run 2 (2015<span><math><mo>−</mo></math></span>2018), about 140 fb⁻¹ of proton–proton collisions at a centre-of-mass energy of 13 TeV were collected by the ATLAS experiment. This review presents the most important Run 2 results obtained by the ATLAS Collaboration regarding the properties of the Higgs boson and its interactions with other particles. The performed studies significantly enhance the understanding of the Higgs boson, while hunting for deviations from the predictions of the Standard Model of particle physics.</div></div>","PeriodicalId":404,"journal":{"name":"Physics Reports","volume":"1116 ","pages":"Pages 4-56"},"PeriodicalIF":23.9,"publicationDate":"2024-11-16","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143760869","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"物理与天体物理","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Ultrafast demagnetization in ferromagnetic materials: Origins and progress","authors":"Xiaowen Chen ,&nbsp;Roman Adam ,&nbsp;Daniel E. Bürgler ,&nbsp;Fangzhou Wang ,&nbsp;Zhenyan Lu ,&nbsp;Lining Pan ,&nbsp;Sarah Heidtfeld ,&nbsp;Christian Greb ,&nbsp;Meihong Liu ,&nbsp;Qingfang Liu ,&nbsp;Jianbo Wang ,&nbsp;Claus M. Schneider ,&nbsp;Derang Cao","doi":"10.1016/j.physrep.2024.10.008","DOIUrl":"10.1016/j.physrep.2024.10.008","url":null,"abstract":"<div><div>Since the discovery of ultrafast demagnetization in Ni thin films in 1996, laser-induced ultrafast spin dynamics have become a prominent research topic in the field of magnetism and spintronics. This development offers new possibilities for the advancement of spintronics and magnetic storage technology. The subject has drawn a substantial number of researchers, leading to a series of research endeavors. Various models have been proposed to elucidate the physical processes underlying laser-induced ultrafast spin dynamics in ferromagnetic materials. However, the potential origins of these processes across different material systems and the true contributions of these different origins remain challenging in the realm of ultrafast spin dynamics. This predicament also hinders the development of spintronic terahertz emitters.</div><div>In this review, we initially introduce the different experimental methods used in laser-induced ultrafast spin dynamics. We then systematically explore the magnetization precession process and present seven models of ultrafast demagnetization in ferromagnetic materials. Subsequently, we discuss the physical processes and research status of four ultrafast demagnetization origins (including spin-flipping, spin transport, non-thermal electronic distribution, and laser-induced lattice strain). Since attosecond laser technique and antiferromagnetic materials exhibit promising applications in ultrahigh-frequency spintronics, we acknowledge the emerging studies used by attosecond pulses and studies on ultrafast spin dynamics in antiferromagnets, noting the significant challenges that need to be addressed in these burgeoning field.</div></div>","PeriodicalId":404,"journal":{"name":"Physics Reports","volume":"1102 ","pages":"Pages 1-63"},"PeriodicalIF":23.9,"publicationDate":"2024-11-14","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142653221","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"物理与天体物理","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Large fluctuations and primordial black holes","authors":"Sayantan Choudhury ,&nbsp;M. Sami","doi":"10.1016/j.physrep.2024.10.007","DOIUrl":"10.1016/j.physrep.2024.10.007","url":null,"abstract":"<div><div>In this paper, we review in detail different mechanisms of generation of large primordial fluctuations and their implications for the production of primordial black holes (PBHs) and scalar-induced secondary gravity waves (SIGW), with the ultimate aim of understanding the impact of loop correction on quantum correlations and the power spectrum. To accomplish the goal, we provide a concise, comprehensive, but in depth review of conceptual and technical details of the standard model of the universe, namely, causal structure and inflation, quantization of primordial perturbations and field theoretic techniques such as “in-in” formalism needed for the estimation of loop correction to the power spectrum. We discuss at length the severe constraints (no-go) on PBH production in single-field inflation imposed by appropriately renormalized quantum loop corrections, computed while maintaining the validity of the perturbation framework and assuming sufficient inflation to address the causality problem. Thereafter, we discuss in detail the efforts to circumvent the no-go result in Galileon inflation, multiple sharp transition (MST)-induced inflation, and stochastic single field inflation using an effective field theoretic (EFT) framework applicable to a variety of models. We provide a thorough analysis of the Dynamical Renormalization Group (DRG) resummation approach, adiabatic and late-time renormalization schemes, and their use in producing solar and sub-solar mass PBHs. Additionally, we give a summary of how scalar-induced gravitational waves (SIGWs) are produced in MST setups and Galileon inflation. Finally, the PBH overproduction issue is thoroughly discussed.</div></div>","PeriodicalId":404,"journal":{"name":"Physics Reports","volume":"1103 ","pages":"Pages 1-276"},"PeriodicalIF":23.9,"publicationDate":"2024-11-13","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142664028","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"物理与天体物理","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Majorana quasiparticles in atomic spin chains on superconductors","authors":"Stephan Rachel ,&nbsp;Roland Wiesendanger","doi":"10.1016/j.physrep.2024.10.005","DOIUrl":"10.1016/j.physrep.2024.10.005","url":null,"abstract":"<div><div>For the past decade, Majorana quasiparticles have become one of the hot topics in condensed matter research. Besides the fundamental interest in the realization of particles being their own antiparticles, going back to basic concepts of elementary particle physics, Majorana quasiparticles in condensed matter systems offer exciting potential applications in topological quantum computation due to their non-Abelian quantum exchange statistics. Motivated by theoretical predictions about possible realizations of Majorana quasiparticles as zero-energy modes at boundaries of topological superconductors, experimental efforts have focussed in particular on quasi-one-dimensional semiconductor–superconductor and magnet–superconductor hybrid systems. However, an unambiguous proof of the existence of Majorana quasiparticles is still challenging and requires considerable improvements in materials science, atomic-scale characterization and control of interface quality, as well as complementary approaches of detecting various facets of Majorana quasiparticles. Bottom-up atom-by-atom fabrication of disorder-free atomic spin chains on atomically clean superconducting substrates has recently allowed deep insight into the emergence of topological sub-gap Shiba bands and associated Majorana states from the level of individual atoms up to extended chains, thereby offering the possibility for critical tests of Majorana physics in disorder-free model-type 1D hybrid systems.</div></div>","PeriodicalId":404,"journal":{"name":"Physics Reports","volume":"1099 ","pages":"Pages 1-28"},"PeriodicalIF":23.9,"publicationDate":"2024-11-07","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142658262","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"物理与天体物理","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"The energy level spectrum of the yellow excitons in cuprous oxide","authors":"J. Heckötter ,&nbsp;A. Farenbruch ,&nbsp;D. Fröhlich ,&nbsp;M. Aßmann ,&nbsp;D.R. Yakovlev ,&nbsp;M. Bayer ,&nbsp;M.A. Semina ,&nbsp;M.M. Glazov ,&nbsp;P. Rommel ,&nbsp;J. Ertl ,&nbsp;J. Main ,&nbsp;H. Stolz","doi":"10.1016/j.physrep.2024.10.004","DOIUrl":"10.1016/j.physrep.2024.10.004","url":null,"abstract":"&lt;div&gt;&lt;div&gt;This article discusses the experimental status achieved in the assessment of the hydrogen-like series of Wannier–Mott excitons, using the semiconductor cuprous oxide, Cu&lt;span&gt;&lt;math&gt;&lt;msub&gt;&lt;mrow&gt;&lt;/mrow&gt;&lt;mrow&gt;&lt;mn&gt;2&lt;/mn&gt;&lt;/mrow&gt;&lt;/msub&gt;&lt;/math&gt;&lt;/span&gt;O, as material platform. While for other crystals the observed exciton series are limited to low principal quantum numbers &lt;span&gt;&lt;math&gt;&lt;mi&gt;n&lt;/mi&gt;&lt;/math&gt;&lt;/span&gt; and typically a particular orbital angular momentum &lt;span&gt;&lt;math&gt;&lt;mi&gt;L&lt;/mi&gt;&lt;/math&gt;&lt;/span&gt;, recently a major extension of the number of detected states has been achieved for the so-called yellow exciton series in cuprous oxide. About 60 quantum number combinations &lt;span&gt;&lt;math&gt;&lt;mrow&gt;&lt;mo&gt;(&lt;/mo&gt;&lt;mi&gt;n&lt;/mi&gt;&lt;mo&gt;,&lt;/mo&gt;&lt;mi&gt;L&lt;/mi&gt;&lt;mo&gt;)&lt;/mo&gt;&lt;/mrow&gt;&lt;/math&gt;&lt;/span&gt;, defining different shells of possible exciton states, were detected in high-resolution one-photon absorption and second harmonic generation spectroscopy, also complemented with application of external electric or magnetic fields. The extension concerns not only the optically active states (the orthoexcitons) that are allowed in different orders of light–matter coupling, but also the states that are optically forbidden due to spin conservation in optical transitions (the paraexcitons). The hydrogen model provides a good overall description of the exciton level spectrum. However, an analysis with sufficient energy resolution reveals significant deviations evidenced by shell splittings, which arise from breaking of the rotational into discrete symmetries in the cubic crystal environment. The resulting fine structure splitting between different shells and within a shell &lt;span&gt;&lt;math&gt;&lt;mrow&gt;&lt;mo&gt;(&lt;/mo&gt;&lt;mi&gt;n&lt;/mi&gt;&lt;mo&gt;,&lt;/mo&gt;&lt;mi&gt;L&lt;/mi&gt;&lt;mo&gt;)&lt;/mo&gt;&lt;/mrow&gt;&lt;/math&gt;&lt;/span&gt; is mainly determined by the valence band dispersion in Cu&lt;span&gt;&lt;math&gt;&lt;msub&gt;&lt;mrow&gt;&lt;/mrow&gt;&lt;mrow&gt;&lt;mn&gt;2&lt;/mn&gt;&lt;/mrow&gt;&lt;/msub&gt;&lt;/math&gt;&lt;/span&gt;O showing pronounced band mixing effects. The corresponding extensions in the exciton Hamiltonian bear similarity to those causing the fine structure splitting in hydrogen, namely a higher order kinetic energy term and a spin–orbit coupling term. In addition, the electron–hole exchange interaction arising for the orthoexcitons and corrections to the dielectric screening provide further contributions to the fine structure splitting. As a consequence, the hydrogen wavefunctions are valid only approximately for describing excitons, being in fact coupled in the exciton envelopes. Despite the broken &lt;span&gt;&lt;math&gt;&lt;mi&gt;L&lt;/mi&gt;&lt;/math&gt;&lt;/span&gt;-degeneracy of the exciton levels, further symmetry protected degeneracies remain, which can be removed by applying external fields. We describe the evolution of the fine structure spectrum in electric and magnetic fields towards Stark ladders and Landau fans, respectively. The optical spectra depend on the crystal orientation relative to the external field in addition to their dependence on the chosen optical axis. Also, the deviations from an isotropic medium become obvious, as the symm","PeriodicalId":404,"journal":{"name":"Physics Reports","volume":"1100 ","pages":"Pages 1-69"},"PeriodicalIF":23.9,"publicationDate":"2024-11-07","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142659335","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"物理与天体物理","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Network modeling and topology of aging","authors":"Li Feng ,&nbsp;Dengcheng Yang ,&nbsp;Sinan Wu ,&nbsp;Chengwen Xue ,&nbsp;Mengmeng Sang ,&nbsp;Xiang Liu ,&nbsp;Jincan Che ,&nbsp;Jie Wu ,&nbsp;Claudia Gragnoli ,&nbsp;Christopher Griffin ,&nbsp;Chen Wang ,&nbsp;Shing-Tung Yau ,&nbsp;Rongling Wu","doi":"10.1016/j.physrep.2024.10.006","DOIUrl":"10.1016/j.physrep.2024.10.006","url":null,"abstract":"<div><div>Aging is a universal process of age-dependent physiological and functional declines that are strongly associated with human diseases. Despite extensive studies of the molecular causes of aging, little is known about the overall landscape of how aging proceeds and how it is related with intrinsic and extrinsic agents. Aging is a complex trait involving a large number of interdependent factors that change over spatiotemporal scales like a complex system. We develop an interdisciplinary form of statistical mechanics to reconstruct aging-related informative, dynamic, omnidirectional, and personalized networks (idopNetworks) from experimental or clinical data. The idopNetwork model can reveal how a specific biological entity, such as genes, proteins, or metabolites, mediates the antedependence of aging (i.e., the dependence of current trait values on their previous expression), identify how spatiotemporal crosstalk across different organs accelerate or decelerate the rate of aging, and predict how an individual’s chronological age differs from his biological age. We implement GLMY homology theory to dissect the topological architecture and function of aging networks, identifying key subnetworks, surface holes and cubic voids that shape the rate of aging. Aging studies can be ideally conducted by monitoring molecular, physiological, and clinical traits over the full lifecycle. However, it is both impossible and ethically impermissible to collect the kind of data from which idopNetworks are reconstructed. To overcome this limitation, we integrate an allometric scaling law into the model to extract dynamics from snapshots of static data from a population-based cross-sectional study, expanding the utility of the model to a broader domain of cohort data. We show how this model can be used to unravel and predict the biological mechanisms underlying aging by analyzing an experimental metabolic data set of multiple brain regions in the aging mouse and a cross-sectional physiological data set of the lung for smoking and nonsmoking males aged from 20 years to nearly centenarians from the China Pulmonary Health Study. The model opens up a new horizon for studying how aging occurs through intrinsic and extrinsic interactions and could be used as a generic tool to disentangle human aging using various types of molecular, phenotypic or clinical data.</div></div>","PeriodicalId":404,"journal":{"name":"Physics Reports","volume":"1101 ","pages":"Pages 1-65"},"PeriodicalIF":23.9,"publicationDate":"2024-11-07","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142652789","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"物理与天体物理","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}