Interdisciplinary Medical Journal最新文献_第2页

Local and systemic side effects of the coronanovac vaccine 冠状病毒疫苗的局部和全身副作用

Interdisciplinary Medical Journal Pub Date : 2023-08-31 DOI: 10.17944/interdiscip.1351864

A. Karaoğullarından, S. Erkan, B. Tuhanioğlu, İlhami Yildirim, Asena Ayça Özdemir

{"title":"Local and systemic side effects of the coronanovac vaccine","authors":"A. Karaoğullarından, S. Erkan, B. Tuhanioğlu, İlhami Yildirim, Asena Ayça Özdemir","doi":"10.17944/interdiscip.1351864","DOIUrl":"https://doi.org/10.17944/interdiscip.1351864","url":null,"abstract":"Objective: Vaccines are biological products that provide protection against diseases by stimulating the immune system. Our aim in this study is to examine local and systemic side effects after inactivated coronavirus vaccination. In addition, when these side effects started, how long they lasted and their effect on daily life were evaluated.\u0000\u0000Methods: 224 healthcare workers who met the study criteria and were vaccinated against coronavirus in Adana City Training and Research Hospital were included in the study. A questionnaire prepared by us was filled in for these patients in which we inquired about the local and systemic side effects of the vaccine, the onset of side effects, their duration, whether they affect daily life, the need for drug use, and some demographic data. The survey results were evaluated with the SPSS statistical program. Local and systemic side effects were evaluated according to age, gender, allergy status, onset time, duration of effect, effect on daily life, and use of medical treatment.\u0000\u0000Results: At least one side effect was observed in 73.2% of 224 patients, while no side effects were observed in 26.8%. Being under the age of 35, being female, and being allergic increased the side effects (p:0.0027, p:0.001, p.0.031). In the logistic regression analysis, it was seen that being a woman was more effective (p.0.002). The most common local side effect was at the injection site pain was 76.2%, the most common systemic side effect was weakness 40.9%. 85.6% of local side effects and 70.4% of systemic side effects were seen in the first 24 hours. 71.3% of local side effects and 70.1% of systemic side effects lasted less than 24 hours.\u0000\u0000Conclusion: Inactivated covid-19 vaccine causes side effects in the majority of patients.In the otorhinolaryngology outpatient clinic, attention should be paid to the side effects of the coronovac vaccine in female patients under the age of 35 who have allergies.","PeriodicalId":402691,"journal":{"name":"Interdisciplinary Medical Journal","volume":"19 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2023-08-31","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"116903878","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Determination of 25 hydroxyvitamin D reference ranges in Hatay region by indirect method 间接法测定哈泰地区25个羟维生素D标准范围

Interdisciplinary Medical Journal Pub Date : 2023-08-25 DOI: 10.17944/interdiscip.1352036

Hamdi Oğuzman, Serdar Doğan

{"title":"Determination of 25 hydroxyvitamin D reference ranges in Hatay region by indirect method","authors":"Hamdi Oğuzman, Serdar Doğan","doi":"10.17944/interdiscip.1352036","DOIUrl":"https://doi.org/10.17944/interdiscip.1352036","url":null,"abstract":"Objective: The aim of this study is to determine the reference ranges of 25 hydroxyvitamin D (25(OH)D) levels from the serum 25(OH)D results of the patients and to investigate variations across age and gender groups. \u0000 \u0000Methods: The patients (n=26829) who applied to Hatay Mustafa Kemal University Hospital between January 2018 and December 2019 and whose 25(OH)D levels were studied were included in this retrospective study. Serum 25(OH)D levels were studied by the chemiluminescence immunoassay method. The hospital information management system was used to obtain the test results and patient data. The indirect method was used to determine the reference ranges. \u0000 \u0000Results: The prevalence of 25(OH)D deficiency in the patients participating in this study was 60.9% in the general population, 54.9% in men, and 67.5% in women. It has been observed that 25(OH)D deficiency is more common in women than in men. The reference ranges determined in this study were lower than the reference ranges provided by the manufacturer. \u0000 \u0000Conclusion: In this study, 25(OH)D levels and reference ranges of Hatay Region were determined in a very large population. It can be said that the results of our region will contribute to the studies to be carried out on the determination of 25(OH)D levels and reference ranges throughout the country.","PeriodicalId":402691,"journal":{"name":"Interdisciplinary Medical Journal","volume":"119 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2023-08-25","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"125206335","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Relationship between atrial fibrillation and P wave dispersion in inpatients with COVID-19 COVID-19 患者心房颤动与 P 波频散之间的关系

Interdisciplinary Medical Journal Pub Date : 2023-08-25 DOI: 10.17944/interdiscip.1410386

Hayati Eren, M. Omar, Ü. Kaya, Sedat Akkan, Zehra Demirbaş

引用次数: 0

The frequency and associated factors of infusion-related reactions to rituximab for patients with rheumatoid arthritis 类风湿性关节炎患者利妥昔单抗输注相关反应的频率及相关因素

Interdisciplinary Medical Journal Pub Date : 2023-08-10 DOI: 10.17944/interdiscip.1351896

M. Pekdiker

{"title":"The frequency and associated factors of infusion-related reactions to rituximab for patients with rheumatoid arthritis","authors":"M. Pekdiker","doi":"10.17944/interdiscip.1351896","DOIUrl":"https://doi.org/10.17944/interdiscip.1351896","url":null,"abstract":"Objectives: Rituximab is an effective biological agent for treating patients with rheumatoid arthritis (RA). Rheumatologists can avoid rituximab therapy because of infusion-related reactions (IRR). There is a lack of data about rituximab-related IRR, especially in rituximab-naïve patients with RA; therefore, we aimed to determine the frequency and associated factors of rituximab-related IRR in these patients.\u0000\u0000Methods: Baseline demographic, laboratory, and treatment data were noted. One course of rituximab was used in two infusions to 95 rituximab-naïve patients with RA. Standardized premedication was administered before infusions. Rates, severity, and management of IRR were recorded. Efficacy and infections were also noted if there were.\u0000\u0000Results: Ninety-four of 95 patients completed the rituximab course successfully. We observed a total of 23 IRRs in 20 patients. The frequency of IRR was 12.1%, and serious IRR was 0.52%. Grade 1-2-3 IRRs had a rate of 52.2%, 30.4%, and 17.4%, respectively; grade 4 or 5 IRR wasn’t detected. Age <60 years, anti-CCP <200U/ml and absence of biologic agent use before rituximab was significantly higher in patients with IRR than without IRR (p=0.01, p=0.002, p=0.01 respectively). We found out that if only the disease age is above 60 months, it is protective against IRR as per the results of multivariate model analysis.\u0000\u0000Conclusion: Results supported that rituximab is a safe biological agent option for patients with RA at secondary central hospitals. Identified risk factors of IRR need to be corroborated in larger studies for safer rituximab therapy.","PeriodicalId":402691,"journal":{"name":"Interdisciplinary Medical Journal","volume":"1 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2023-08-10","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"129281061","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

The prognostic role of neutrophil/lymphocyte ratio and monocyte/lymphocyte ratio in advanced stage gastric cancer patients receiving chemotherapy: a single center experience 中性粒细胞/淋巴细胞比率和单核细胞/淋巴细胞比率在晚期胃癌化疗患者预后中的作用:单中心经验

Interdisciplinary Medical Journal Pub Date : 2023-08-10 DOI: 10.17944/interdiscip.1351892

Kubilay Karaboyun, E. Şeber

{"title":"The prognostic role of neutrophil/lymphocyte ratio and monocyte/lymphocyte ratio in advanced stage gastric cancer patients receiving chemotherapy: a single center experience","authors":"Kubilay Karaboyun, E. Şeber","doi":"10.17944/interdiscip.1351892","DOIUrl":"https://doi.org/10.17944/interdiscip.1351892","url":null,"abstract":"Objective: Several studies revealed that peripheral blood Neutrophil/Lymphocyte ratio (NLR) and Monocyte/Lymphocyte Ratio (MLR) were prognostic in various cancer types. However, there are no excessive information about the prognostic significance of NLR and MLR in patients with advanced gastric cancer. As a result, we examined whether NLR and/or MLR could be used as a prognostic marker to predict survival outcomes in patients with advanced gastric cancer receiving palliative chemotherapy. \u0000 \u0000Method: We retrospectively analyzed 119 patients with gastric cancer receiving chemotherapy. We evaluated the relationship between potential prognostic factors and overall survival (OS) times using the Kaplan-Meier method and Cox regression survival modelling. \u0000 \u0000Results: The median overall survival of the patients was 6.9 (2.1-41.6) months. In univariate analysis, NLR (p< 0.001), ECOG performance status (p< 0.001), presence of liver metastases (p< 0.001) and presence of peritoneal metastases (p< 0.001) were found to be associated with survival. The multivariate survival model showed the high NLR (HR=1.59, 95% CI 1.6-2.40, p= 0.026), the patients with ECOG performance score 2-3 (HR=2.91, 95% CI 1.60-5.27, p","PeriodicalId":402691,"journal":{"name":"Interdisciplinary Medical Journal","volume":"509 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2023-08-10","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"134261303","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Evaluation of dermatology consultations requested for inpatients in a tertiary institution from Türkiye 评估皮肤科咨询要求住院患者在三级机构从<s:1> rkiye

Interdisciplinary Medical Journal Pub Date : 2023-08-09 DOI: 10.17944/interdiscip.1320530

Pelin Hizli, Mehmet Enes Sevgi̇li̇, A. Kiliç

{"title":"Evaluation of dermatology consultations requested for inpatients in a tertiary institution from Türkiye","authors":"Pelin Hizli, Mehmet Enes Sevgi̇li̇, A. Kiliç","doi":"10.17944/interdiscip.1320530","DOIUrl":"https://doi.org/10.17944/interdiscip.1320530","url":null,"abstract":"Objective: To investigate and present the features of the consultations requested for inpatients in a tertiary institution retrospectively. \u0000 \u0000Method: Archive of our tertiary institution located in the South Marmara Region of Turkiye was reviewed and every single consultation responded by Dermatology Department was investigated. \u0000 \u0000Results: The mean age of the 421 consulted patients (191 females, 230 males) was 62 ± 17 (1-95) years. The most frequently consultation requesting departments were Cardiology (18.8%), Neurology (11.4%) and Physical medicine and Rehabilitation (8.3%). The most common lesions resulting in consultation were rashes (22.3%), erythematous lesions (14.5%) and wounds (14%). The most common dermatologic diagnoses were contact dermatitis (10.7%), tinea pedis (8%) and cellulitis (5.2%). Among 421 patients, 62 (14.7%) patients required a histopathologic diagnosis and underwent biopsy. Most frequent histopathologic diagnoses were non-specific findings 14 (22.6%), basal cell carcinoma (12.9%), maculopapular drug reaction (12.9%) and contact dermatitis (9.7%). \u0000 \u0000Conclusion: The perspective of interdisciplinary approach leads physicians request dermatology consultations frequently for inpatients particularly having systemic diseases and reviewing and reporting the features of consulted patients periodically might provide a satisfactory contribution to the current literature.","PeriodicalId":402691,"journal":{"name":"Interdisciplinary Medical Journal","volume":"24 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2023-08-09","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"122335682","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Comparison of efficacy of Ketorolac %0.4 and Dexamethasone %0.1 in inflamed Pterygium and Pinguecula 酮咯酸%0.4与地塞米松%0.1治疗炎症性翼状胬肉及扁平胬肉的疗效比较

Interdisciplinary Medical Journal Pub Date : 2023-08-08 DOI: 10.17944/interdiscip.1352006

Kaan Çakmak, Safak Korkmaz, F. Yilmaz

{"title":"Comparison of efficacy of Ketorolac %0.4 and Dexamethasone %0.1 in inflamed Pterygium and Pinguecula","authors":"Kaan Çakmak, Safak Korkmaz, F. Yilmaz","doi":"10.17944/interdiscip.1352006","DOIUrl":"https://doi.org/10.17944/interdiscip.1352006","url":null,"abstract":"Objective: This study investigated the effect of the ketorolac %0.4 and dexamethasone %0.1 on suppressing symptoms in inflamed pterygium and pinguecula. \u0000 \u0000Methods: 50 patients were included in the study. The patients were divided into two groups, each consisting of 25 patients. Ketorolac %0.4 eye drops were dropped in group 1, and dexamethasone %0.1 eye drops were started in group 2. Groups were compared 3,7,14,30,45. days in terms of total signs and symptoms. \u0000 \u0000Results: After 14 days of drug administration group 1, scores were reduced %85 for total signs (2.52+1.16, p=0.001), %86 for total symptoms (4.10+2.61, p=0.001) and total scores showed a significant reduction of %86 (6.62+2.91, p=0.001) for the score. After 14 days of drug administration in group 2, scores were reduced %85 for total signs (2.70+1.46, p=0.001), %86 for total symptoms (4.25+2.36, p=0.001), and total scores showed a significant reduction of %86 (7.10+2.99, p=0.001) for the score. The scores for each sign and symptom decreased during the study. However, the statistical evaluation of each sign and symptom was similar in groups 1 and 2. There was no difference between groups 1 and 2 for total signs, total symptoms, and total score on days 3,7 and 14. No significant difference was found between groups 1 and 2 for total signs, total symptoms, and total score on days 14,30 and 45 (p>0.05). \u0000 \u0000Conclusion: Current study revealed that topical ketorolac %0.4 solutions are as effective as dexamethasone in treating inflammatory pterygium and pinguecula. We suggest that it can be used alone to treat this disease. We need more studies to support our work.","PeriodicalId":402691,"journal":{"name":"Interdisciplinary Medical Journal","volume":"92 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2023-08-08","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"129858629","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Evaluation of family physicians’ knowledge level, attitudes and behaviours on Asthma, COPD 家庭医生对哮喘、慢性阻塞性肺病的知识水平、态度和行为的评价

Interdisciplinary Medical Journal Pub Date : 2023-07-20 DOI: 10.17944/interdiscip.1351884

A. Yıldız, Celal Kuş, R. Gümüştakım, M. E. Eryilmaz

{"title":"Evaluation of family physicians’ knowledge level, attitudes and behaviours on Asthma, COPD","authors":"A. Yıldız, Celal Kuş, R. Gümüştakım, M. E. Eryilmaz","doi":"10.17944/interdiscip.1351884","DOIUrl":"https://doi.org/10.17944/interdiscip.1351884","url":null,"abstract":"Objective: The most common complaints about chest diseases that we encounter in family practice centers are of asthma and Chronic obstructive pulmonary disease (COPD). Thus, it was aimed to evaluate the attitudes, behaviors and knowledge level of family physicians on asthma and COPD. \u0000 \u0000Methods: Our research is a descriptive cross-sectional study. Our study was conducted between September-November 2019 by including family physicians, family physician research assistants and family physician specialists. 387 physicians participated in the study. The 35-question survey in our study consists of sociodemographic data and consists of questions aiming to evaluate the knowledge level, attitudes and behaviors on asthma-COPD. \u0000 \u0000Results: A total of 387 family physicians including 251 family physicians, 31 family physician specialists and 105 family physician research assistants were included in this study. When the rates of using the spirometry device in suspected asthma-COPD, were compared, the difference between family medicine research assistants and family physicians was found to be statistically significant (p","PeriodicalId":402691,"journal":{"name":"Interdisciplinary Medical Journal","volume":"32 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2023-07-20","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"134373759","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

The relationship between prognostic nutritional index and mortality in patients hospitalized with COVID-19 Pneumonia COVID-19肺炎住院患者预后营养指数与死亡率的关系

Interdisciplinary Medical Journal Pub Date : 2023-07-20 DOI: 10.17944/interdiscip.1352016

M. Sahin, B. Akkök, B. Kizildag, Fulsen Bozkuş, N. Atilla, Hasan Kahraman

引用次数: 0

Surveillance of urine cultures and evaluation gram negative uropathogens;five year data from Erbil 监测尿培养和评估革兰氏阴性尿路病原体;埃尔比勒5年数据

Interdisciplinary Medical Journal Pub Date : 2023-07-14 DOI: 10.17944/interdiscip.1351971

M. Sadeq, Hevi Ghafour, T. Demiray, M. Altındiş

{"title":"Surveillance of urine cultures and evaluation gram negative uropathogens;five year data from Erbil","authors":"M. Sadeq, Hevi Ghafour, T. Demiray, M. Altındiş","doi":"10.17944/interdiscip.1351971","DOIUrl":"https://doi.org/10.17944/interdiscip.1351971","url":null,"abstract":"Objective: Urinary tract infections (UTIs) are most common infectious disease and a public health problem that imposes a large economic burden. Determining the distribution and resistance profiles of uropathogens in a region is important for planning empirical treatments, preventing antimicrobial drug resistance and establishing rational antibiotic use policies. The aim of this study is to gather surveillance data of urine cultures and determine the prevalence of uropathogens in urine samples of patients referred to outpatient clinics in Erbil region and to evaluate the antimicrobial susceptibility of the gram negative uropathogens. \u0000 \u0000Methods: All urine cultures result of patients referred to Erbil hospitals in the last 5 years (2015-2020) are retrospectively examined in this study. Microorganisms are identified by standard bacterial methods and their susceptibilities are assessed by VITEK 2 (bioMérieux, Marcy l’Etoile, France) automated system. \u0000 \u0000Results: The results of urine culture of 3380 suspected UTI cases are examined and out of 3097 positive cultures observed, a total of 1961 (63.3%) isolates are gram-negative and 1136 (36.7%) are gram-positive pathogens. \u0000 \u0000Conclusion: The most common urinary pathogen determined in this study is Escherichia coli. The highest resistances of gram-negative urinary pathogens are against the ampicillin, trimethoprim/sulfamethoxazole and ceftriaxone. It is thought that the data obtained from this study will be useful in the planning of empirical treatment of urinary tract infections and in the development of rational antibiotic use policies.","PeriodicalId":402691,"journal":{"name":"Interdisciplinary Medical Journal","volume":"21 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2023-07-14","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"133989277","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0