Interdisciplinary Medical Journal最新文献_第4页

Evaluation of serum adipocytokine and interleukin-18 levels in patients with epilepsy 癫痫患者血清脂肪细胞因子和白细胞介素-18水平的评价

Interdisciplinary Medical Journal Pub Date : 2023-04-30 DOI: 10.17944/interdiscip.1285784

Ahmet Dündar, Derya Kilinc, A. Yilmaz, Vugar Jafar, Orhan Ayan, M. Çevik, Hamza Aslanhan

{"title":"Evaluation of serum adipocytokine and interleukin-18 levels in patients with epilepsy","authors":"Ahmet Dündar, Derya Kilinc, A. Yilmaz, Vugar Jafar, Orhan Ayan, M. Çevik, Hamza Aslanhan","doi":"10.17944/interdiscip.1285784","DOIUrl":"https://doi.org/10.17944/interdiscip.1285784","url":null,"abstract":"Objective: Epilepsy is a neurological disease characterized by recurrent seizures. The underlying pathophysiological mechanisms in epilepsy are not fully known. Our aim is to investigate the relationship between serum adipocytokine and interleukin (IL)-18 levels in epilepsy patients receiving and not receiving antiepileptic therapy. \u0000 \u0000Method: Our study was established as three groups. I: Epilepsy patients receiving antiepileptic therapy (n=30), II: Newly diagnosed epilepsy patients (n=30) and III: Control group (n=30). Serum adipocytokine and IL-18 levels were measured by enzyme-linked immunoassorbent assay method. \u0000 \u0000Results: It was determined that serum adipocytokine and IL-18 levels were increased in epilepsy patients who received topiramate treatment and did not receive antiepileptic therapy compared to the control group. Serum glucose, total protein, cholesterol and albumin concentrations of patients who received antiepileptic treatment were decreased compared to the control group (p0.05). It was found that the body mass index (BMI) ratio of epilepsy patients who received antiepileptic treatment decreased and was significant compared to the control group and the group that did not receive treatment (p","PeriodicalId":402691,"journal":{"name":"Interdisciplinary Medical Journal","volume":"31 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2023-04-30","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"132729152","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

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Monocyte eosinophil ratio and red blood cell distribution width in the diagnosis of asthma 单核细胞嗜酸性粒细胞比值和红细胞分布宽度在哮喘诊断中的价值

Interdisciplinary Medical Journal Pub Date : 2023-04-30 DOI: 10.17944/interdiscip.1285665

I. Koc, Serdar Doğan

引用次数: 0

The role of surgery in perianal disease developing in hematology malignancy patients 手术在血液恶性肿瘤患者肛周疾病发展中的作用

Interdisciplinary Medical Journal Pub Date : 2023-04-30 DOI: 10.17944/interdiscip.1285614

Serkan Erkan, Ramazan Gündoğdu, M. Kuş, H. Yabanoğlu

{"title":"The role of surgery in perianal disease developing in hematology malignancy patients","authors":"Serkan Erkan, Ramazan Gündoğdu, M. Kuş, H. Yabanoğlu","doi":"10.17944/interdiscip.1285614","DOIUrl":"https://doi.org/10.17944/interdiscip.1285614","url":null,"abstract":"Objective: Perianal diseases may impair the comfort of life in immunosuppressive patients as well as cause life-threatening complications. In this study, we aimed to analyze the surgical management and results of perianal region diseases in hematological patients who were consulted by the hematology clinic and to present non-surgical treatment options in these patients. \u0000\u0000Method: The files of the patients who were consulted by the Hematology Clinic of our hospital between January 2011 and January 2021 due to perianal disease were retrospectively reviewed. Patients with multiple data deficiencies were excluded from the study. Gender, age, hematological diagnosis, neutropenic status, number of consultations, surgical diagnosis, radiological imaging methods, treatment modalities and survival data of the patients were recorded.\u0000\u0000Results: A total of 911 consultations were requested from 627 patients. The number of patients consulted with the diagnosis of perianal disease was 147. Ninety (61.2%) of the patients were male and 57 (38.7%) were female. Of the patients, 74 (50.3%) had acute myeloid leukemia, 29 (19.7%) lymphoma, 15 (10.2%) acute lymphoblastic leukemia, 12 (8.1%) myelodysplastic syndrome, 10 (6.8%) multiple myeloma, 7 (4.7%) of them were followed up with the diagnosis of chronic lymphocytic leukemia, 53 (36%) patients had additional systemic disease besides hematological disease. All patients were examined and prediagnosed. Magnetic resonance imaging was performed in 72 patients with suspected abscess and fistula. Surgical treatment methods were applied to 30 (20.4%) of the patients.\u0000\u0000Conclusion: Perianal diseases frequently accompany hematological diseases, especially in neutropenic periods. With early examination, close follow-up and appropriate treatment, surgical necessity and the number of relapsed diseases can be minimized.","PeriodicalId":402691,"journal":{"name":"Interdisciplinary Medical Journal","volume":"18 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2023-04-30","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"125640460","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

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Evaluation of notifiable infectious diseases between 2018 and 2021 in Van province: A descriptive study 2018 - 2021年凡省法定传染病评估:一项描述性研究

Interdisciplinary Medical Journal Pub Date : 2023-04-30 DOI: 10.17944/interdiscip.1285744

Ömer Faruk Tekin, Müberra ÇAKICI TOSUN

{"title":"Evaluation of notifiable infectious diseases between 2018 and 2021 in Van province: A descriptive study","authors":"Ömer Faruk Tekin, Müberra ÇAKICI TOSUN","doi":"10.17944/interdiscip.1285744","DOIUrl":"https://doi.org/10.17944/interdiscip.1285744","url":null,"abstract":"Objective: In this study, it was aimed to examine the infectious diseases reported in Van province between 2018 and 2021 in terms of various characteristics. \u0000 \u0000Method: It is a descriptive study that was conducted between January 1 and January 31, 2022. Necessary permissions and an ethics committee were obtained for the study. Infectious diseases reported in Van province between January 1, 2018 and September 30, 2021 were examined using the Infectious Diseases Surveillance and Early Warning System (IZCI) of the Ministry of Health. It was examined in terms of various variables. The study’s data were analysed with the Jamovi 2.2 statistical program. Descriptive data were given as numbers and percentages. The Pearson Chi-square test was used for comparisons between categorical variables. \u0000 \u0000Results: There were 16778 notifications between 01.01.2018-30.09.2021. Of the people with the reported disease, 59.5% were men and 40.5% were women. The mean age was 23.3±19.0 (min: 0-max: 99). The 3 most frequently reported diseases/conditions were 32.51% (n=5455) Brucellosis, 31.07% (n=5212) Rabies-risk contact, and 12.70% (n=2131) Rotavirus. There were 5555 (33.1%) disease reports in 2018, 4769 (28.4%) in 2019, 3411 (20.3%) in 2020, and 3043 (18.1%) in the first nine months of 2021. The incidence of Brucellosis, Rabies Risky Contact, Echinococcosis, and Anthrax diseases was found to be higher in rural districts than in urban districts (for each p","PeriodicalId":402691,"journal":{"name":"Interdisciplinary Medical Journal","volume":"26 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2023-04-30","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"130730157","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0