Interdisciplinary Medical Journal最新文献_第3页

Intestinal-type adenocarcinoma of the sinonasal mucosa: a rare case report 鼻粘膜肠型腺癌1例报告

Interdisciplinary Medical Journal Pub Date : 2023-07-10 DOI: 10.17944/interdiscip.1352024

Didar GÜRSOY KUZULUK, Süleyman Uysal, Gül SOYLU ÖZLER

引用次数: 0

Can venous blood gas be used instead of arterial blood gas in emergency department? 急诊科可以用静脉血气代替动脉血气吗?

Interdisciplinary Medical Journal Pub Date : 2023-06-22 DOI: 10.17944/interdiscip.1351843

Y. Erdoğan, A. Karakuş

引用次数: 0

The approach of society regarding the violence against healthcare providers 社会对暴力侵害医疗服务提供者的态度

Interdisciplinary Medical Journal Pub Date : 2023-05-10 DOI: 10.17944/interdiscip.1351983

Yusuf Gazi Uçar, Celal Kuş, R. Gümüştakım, M. E. Eryilmaz

{"title":"The approach of society regarding the violence against healthcare providers","authors":"Yusuf Gazi Uçar, Celal Kuş, R. Gümüştakım, M. E. Eryilmaz","doi":"10.17944/interdiscip.1351983","DOIUrl":"https://doi.org/10.17944/interdiscip.1351983","url":null,"abstract":"Objective: The aim of this study is to investigate the society’s approach to violence and to offer solutions to prevent violence in health. \u0000\u0000Method: This study was conducted in Kahramanmaraş province in February and March 2020. The questionnaire of 50 questions was applied to 1306 people face-to-face.\u0000\u0000Results: 53.8% of our participants were female. Among the people who had an argument with healthcare providers, 53.0% of them were male. 40.2% of the people who had an argument were aged 25-40. 78.1% have a high school or less education. 86.6% of the ones who considered violence as a tool of demanding justice had high school. Only 19.2% of the people who consider violence as demanding justice had information about code white. 82.9% of the people who state that the most significant reason for the violence is the attitude of healthcare providers had a high school or lower level of education. Participants were asked about the reasons for violence, and 44.0% of them answered that it was the presence of angry and aggressive people. \u0000\u0000Conclusion: Violence in the health sector has many complicated and intertwined aspects. Its solution is for the people in charge to do their part.","PeriodicalId":402691,"journal":{"name":"Interdisciplinary Medical Journal","volume":"6 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2023-05-10","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"120989248","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

A case of acalculous cholecystitis or Brucella-induced acute cholecystitis? 无结石性胆囊炎或布鲁氏菌性急性胆囊炎1例?

Interdisciplinary Medical Journal Pub Date : 2023-05-01 DOI: 10.17944/interdiscip.1352029

Fatma Yekta Urkmez, Mustafa Serhat Şahinoğlu, S. Alkan

引用次数: 0

Another neglected symptom among the overweight young: an analysis of the self-reported anterior knee pain scores of the secondary school children 超重的年轻人中另一个被忽视的症状:对中学生自我报告的前膝关节疼痛评分的分析

Interdisciplinary Medical Journal Pub Date : 2023-04-30 DOI: 10.17944/interdiscip.1285723

M. Belibagli, N. AYGÜN BİLECİK

{"title":"Another neglected symptom among the overweight young: an analysis of the self-reported anterior knee pain scores of the secondary school children","authors":"M. Belibagli, N. AYGÜN BİLECİK","doi":"10.17944/interdiscip.1285723","DOIUrl":"https://doi.org/10.17944/interdiscip.1285723","url":null,"abstract":"Objective: Knee pain is the most common joint complaint among the young and is linked with excessive weight by the World Health Organization. The study aimed to define the prevalence of anterior knee pain in secondary school children and search its’ relations to weight and academic performance.\u0000\u0000Method: The cross-sectional and descriptive study was conducted in Adana, between Sept 15 and Oct 15, 2020. Middle school students aged between 10 and 18 years were included. Anterior knee pain was assessed using the Anterior Knee Pain Scale short form (AKPS-SF), and the numerical rating scale (NRS) was used for pain intensity. Data were collected by questionnaires sent by e-mail.\u0000\u0000Results: There were 709 replies eligible for analysis. The NRS mean score was 0.78±1.47 for 249 (35.12 %) participants who reported knee pain. The number of students with an AKPS-SF score of ≤40 in the study group was 46 (6.40%). AKPS-SF scores showed weak negative linear associations with weight and the school year (r=-0.346/p=0.019, and r=-0.292/p=0.049, respectively), and no correlations were found with academic performance.\u0000\u0000Conclusion: The study has shown that more than a third of the students reported various levels of knee pain. The inverse correlation of AKPS-SF with weight and the weak link with the school year might attract the attention of healthcare givers to pay more attention to knee examination and help avoid future impairments in the knee joints of school age children.","PeriodicalId":402691,"journal":{"name":"Interdisciplinary Medical Journal","volume":"28 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2023-04-30","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"115145631","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

The effect of Covid-19 anxiety on prenatal distress and prenatal attachment in pregnant women 新冠肺炎焦虑对孕妇产前窘迫和产前依恋的影响

Interdisciplinary Medical Journal Pub Date : 2023-04-30 DOI: 10.17944/interdiscip.1285742

Dilay Karademir, Ezgi Agadayi, S. Karahan

{"title":"The effect of Covid-19 anxiety on prenatal distress and prenatal attachment in pregnant women","authors":"Dilay Karademir, Ezgi Agadayi, S. Karahan","doi":"10.17944/interdiscip.1285742","DOIUrl":"https://doi.org/10.17944/interdiscip.1285742","url":null,"abstract":"Objective: In this study, we aimed to investigate the effect of Coronavirus Disease 2019 (COVID-19) anxiety on pregnant women, whether it causes prenatal distress and may be changes on mother-infant attachment.\u0000\u0000Method: The research population consists of pregnant women in all trimesters. Exclusion criteria from the study; anomaly risk in the fetus, abnormal examination findings, systemic chronic disease and drug use, presence of diagnosed psychiatric disease, consanguineous marriage between the pregnant woman and her spouse. 323 pregnant women who did not meet these exclusion criteria and agreed to participate in the study were included in this study. In the study data form: Income status, education level, age, gravidity, parity, presence and number of miscarriages, gestational week, smoking status, history of COVID-19 infection, if yes, in which week of pregnancy she had, history of COVID-19 infection in her close family, planned pregnancy, in vitro fertilization-intrauterine insemination (IVF-IUI) or a spontaneous pregnancy status were questionnaired. The patients included in the study were administered the Coronavirus Anxiety Scale (CAS), Revised Prenatal Distress Questionnaire (NuPDQ), Prenatal Attachment Scale (PAS).\u0000\u0000Results: COVID-19 anxiety increases more if close relatives have coronavirus rather than participants themselves. We detected that high coronavirus anxiety also caused an increase in the sub-dimensions of prenatal distress. We also found that high COVID-19 anxiety negatively affects prenatal attachment.\u0000\u0000Conclusion: Pregnant women should be given information and education about the possible effects of coronavirus on their pregnancy during their routine follow-up during the pandemic period. Otherwise, both psychologically and physically unhealthy generations await the whole world.","PeriodicalId":402691,"journal":{"name":"Interdisciplinary Medical Journal","volume":"89 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2023-04-30","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"122058816","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Breast cancer and the molecular mechanism of estrogen signaling 乳腺癌与雌激素信号传导的分子机制

Interdisciplinary Medical Journal Pub Date : 2023-04-30 DOI: 10.17944/interdiscip.1285662

Y. Erzurumlu, Hatice Kübra Doğan

{"title":"Breast cancer and the molecular mechanism of estrogen signaling","authors":"Y. Erzurumlu, Hatice Kübra Doğan","doi":"10.17944/interdiscip.1285662","DOIUrl":"https://doi.org/10.17944/interdiscip.1285662","url":null,"abstract":"Cancer is a complex pathology that occurs due to the uncontrolled proliferation and growth of cells in any organ or tissue of the body. Breast cancer is the most frequently diagnosed cancer among women worldwide and is the second leading cause of cancer-related deaths. Breast cancer is a pathology that exhibits heterogeneity in which genetic and environmental risk factors play a role. Although many treatment approaches have been developed for breast cancer today, the frequency of the number of patients diagnosed with breast cancer and lost their lives due to this reason is increasing in the world. The most significant limitation to the success of the treatment approaches developing drug resistance in breast cancer cells, and the disease relapses after a certain period and exhibits a more aggressive profile. Therefore, understanding the molecular biology of breast cancer is essential for developing potent therapeutic approaches. It is known that the development of breast cancer is related to changes in direct and indirect signaling mechanisms mediated by estrogen and estrogen receptor. These signaling mechanisms exhibit highly complex interaction patterns. This review summarizes the pathology of breast cancer, estrogenic compounds, estrogen receptors, genomic and non-genomic molecular signaling mechanisms mediated by estrogen and estrogen receptor.","PeriodicalId":402691,"journal":{"name":"Interdisciplinary Medical Journal","volume":"2 6","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2023-04-30","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"132331442","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Genetic and clinical characteristics of Turkish children with Maturity Onset Diabetes of the Young Type 2 (MODY2): A single center experience 土耳其儿童成熟型2型糖尿病(MODY2)的遗传和临床特征:单中心经验

Interdisciplinary Medical Journal Pub Date : 2023-04-30 DOI: 10.17944/interdiscip.1285735

Ö. Nalbantoğlu, S. Gürsoy, Tarık Kırkgöz, F. Hazan, B. Özkan

{"title":"Genetic and clinical characteristics of Turkish children with Maturity Onset Diabetes of the Young Type 2 (MODY2): A single center experience","authors":"Ö. Nalbantoğlu, S. Gürsoy, Tarık Kırkgöz, F. Hazan, B. Özkan","doi":"10.17944/interdiscip.1285735","DOIUrl":"https://doi.org/10.17944/interdiscip.1285735","url":null,"abstract":"Objective: The aim of the study was to investigate the clinical and molecular genetic characteristics of children with maturity-onset diabetes of the youth-glucokinase (MODY-GCK, MODY type 2).\u0000\u0000Method: Medical files of 21 patients with suspected MODY-GCK were reviewed retrospectively. The file records of the clinical findings, laboratory results and the suspected clinical diagnoses of MODY were based on (1) asymptomatic fasting hyperglycemia (glucose ≥100mg/dl, HbA1c < 7.5% (at least twice measurement) 2) parents with a history of diabetes without complications or mild fasting hyperglycemia (100-144mg/dL).\u0000\u0000Results: The mean age at diagnosis was 11.5±4.3 years (min-max, 1.9-17.2). The mean (SD) fasting blood glucose level was 119.1 (9.8) mg/dL. The mean (SD) fasting C-peptide level was 1.3 (0.7) ng/mL, the mean (SD) insulin level was 5.9 (2.3) IU/ml, and the mean (SD) HbA1c level at diagnosis was 6.2 (0.5) %. Among 12 variants detected in the GCK gene, 8 were missense mutation, 2 were non-sense mutation, 1 of them was splice site and 1 of them was frameshift mutation. Eight of them (p. Val227Met, p. Ser282Ala, p.Val183Met, p.Met239Thr, p.Arg304Gln, p.Thr229Met, p.Gly163Asp, p.Cys130Ter) have been previously reported in the literature and 4 variants (c.582+4delA, p.Glu436Ter, p.His106ThrfsTer11, p.Asp133Gly) were novel.\u0000\u0000Conclusion: We found similar phenotype characteristic of children with GCK-MODY among the children with different variants. The most common mutation type was missense and followed by nonsense, splice site and frameshift mutations. Detection of the molecular defect in patients with MODY is vital for the implementation of appropriate treatment approaches.","PeriodicalId":402691,"journal":{"name":"Interdisciplinary Medical Journal","volume":"4 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2023-04-30","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"129562600","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Prognosis and risk factors of chronicity in childhood idiopathic thrombocytopenic purpura: a single-center experience 儿童特发性血小板减少性紫癜的预后和慢性危险因素:单中心经验

Interdisciplinary Medical Journal Pub Date : 2023-04-30 DOI: 10.17944/interdiscip.1285793

H. Cakmak, K. Kocabay

引用次数: 0

Evaluation of the Covid-19 vaccine literacy of the under-vaccinated community in a district in the covid-19 pandemic; example of pursaklar 2019冠状病毒病大流行中某地区疫苗接种不足社区Covid-19疫苗素养评价pursaklar的例子

Interdisciplinary Medical Journal Pub Date : 2023-04-30 DOI: 10.17944/interdiscip.1285803

Hacer Demirköse, Furkan Akyüz, M. E. Gökler

引用次数: 0