{"title":"The relationship of preterm birth with fetal fibronectin level in cervicovaginal fluid and cervical lenght in ultrasonography","authors":"Anıl Arpaci, Oya SOYLU KARAPINAR","doi":"10.17944/interdiscip.1329535","DOIUrl":"https://doi.org/10.17944/interdiscip.1329535","url":null,"abstract":"Objective: In this study, the compatibility between fetal fibronectin determination and the use of cervical length measured by transvaginal ultrasonography of patients who were at risk of preterm birth in the examination performed at 24-34 weeks of gestation, and patients with an increased risk of preterm birth according to the result were defined. Method: 40 patients who applied to Mustafa Kemal University Training and Research Hospital Gynecology and Obstetrics outpatient clinic between May 2021 and May 2022 were included in the study. Fibronectin results were evaluated using the liquid ELISA method taken from the vaginal secretion by a swap. Cervical lengths were evaluated as 25 mm and below, between 25-30 mm and 30 mm and above in statistical data. Results: For fFN-positive patients, the preterm delivery rate of patients with a cervical length of 25 mm and less was determined as 100%, while the rate of preterm birth was determined as 77.8% for patients with a cervical length between 25 mm and 30 mm. In addition, the preterm labor rate of fFN-positive patients with a cervical length of 30 mm and above was determined as 78.57%. Conclusion: All patients with a cervical length of 25 mm or less have a positive fFN test, and a strong correlation can be established between these two values. Accordingly, fFN positivity was found to have a higher sensitivity in determining the probability of preterm delivery compared to the cervical length ratio.","PeriodicalId":402691,"journal":{"name":"Interdisciplinary Medical Journal","volume":"87 5","pages":""},"PeriodicalIF":0.0,"publicationDate":"2023-12-21","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"139166954","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Assessment of relationship between different communication methods and treatment compliance in orthodontic patients during Covid-19 pandemics","authors":"Hakkı Yılmaz, F. Bilgiç, İlter Burak Köse","doi":"10.17944/interdiscip.1410399","DOIUrl":"https://doi.org/10.17944/interdiscip.1410399","url":null,"abstract":"Objective: The aim of this study was to minimize impairment in oral hygiene and failure of brackets; therefore, effects of pandemic on treatment duration, by communicating our patients using 4 different methods during Covid-19 pandemic. Methods: In the study, 227 patients undergoing fixed orthodontic treatment were included. Five groups were designed: WhatsApp group, short message service (SMS) group, Teledentistry group, e-mail group and control group. During quarantine period, patients were contacted for 4 times and same text was sent to patients. After pandemics, the patients were assessed using mucogingival index (MGI), orthodontic plaque index (OPI) and failure of brackets was determined. Results: In MGI, percentage of patients with healthy result were as follows: WhatsApp group, 83.7%; SMS group, 87.8%; Teledentistry group, 83.7%; E-mail group, 77.5%; control group, 72.2% and no significant difference was found (p>0.05). The OPI scores were as follows: 1.12±1.24 in WhatsApp group; 1.27±1.28 in SMS group; 1.24±1.38 in Teledentistry group; 1.00±1.22 in E-mail group; and 1.61±1.25 in the control group and no significant difference was found (p>0.05). The mean number of brackets broken was 0.47±0.88 in WhatsApp group, 0.39±0.83 in SMS group, 0.51±1.00 in Teledentistry group, 0.40±0.67 in E-mail group and 0.44±0.86 in the control group and no significant difference was found (p>0.05). Conclusion: It was determined that communicating with patients in different ways did not make any difference in terms of the subjects investigated in the study. It was concluded that it would be more appropriate to conduct new studies including social and psychological evaluations.","PeriodicalId":402691,"journal":{"name":"Interdisciplinary Medical Journal","volume":"21 7","pages":""},"PeriodicalIF":0.0,"publicationDate":"2023-12-21","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"139167418","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Yusuf Yeşi̇l, M. Altındiş, H. Toptan, Elmas Pınar Kahraman Kılbaş, O. Bi̇rcan, Ömer Özgür, B. Elmas, Mehmet Köroğlu
{"title":"Diagnostic evaluation of viral versus bacterial tonsillopharyngitis using an artificial intelligence mobile application and symptom questionnaire","authors":"Yusuf Yeşi̇l, M. Altındiş, H. Toptan, Elmas Pınar Kahraman Kılbaş, O. Bi̇rcan, Ömer Özgür, B. Elmas, Mehmet Köroğlu","doi":"10.17944/interdiscip.1297115","DOIUrl":"https://doi.org/10.17944/interdiscip.1297115","url":null,"abstract":"Objective: In this study, it was aimed to distinguish bacterial/viral tonsillopharyngitis (TP) by scoring the symptom and throat images of pediatric patients with artificial intelligence-based mobile application. Method: Fifty-one patients who applied to Sakarya University Training and Research Hospital, Department of Pediatrics and Diseases with acute tonsillopharyngitis were included. Samples were taken from patients and mouth/throat pictures were taken so that the tonsils and pharynx were clearly visible. In the microbiology laboratory, identification with culture/MALDI-TOF MS (Biomerieux, France) from the first samples, and nucleic acid isolation from the other for molecular tests were performed. Symptoms such as fatigue, sore throat, muscle pain, cough, sneezing, and runny nose were questioned from each patient on a scale of 1 to 5. By uploading the symptom results and throat pictures to the artificial intelligence application, it was aimed to distinguish bacterial/viral tonsillopharyngitis with the developed scoring system. Results: Of the 51 samples included in the study, 21 were culture positive and 30 were negative. The artificial intelligence application was defined as 20 out of 21 culture-positive samples, 3 out of 30 culture-negative samples as bacterial tonsillopharyngitis (Sensitivity: 95.2%, specificity: 90%). Conclusion: This study is one of the first to bring together the artificial intelligence application and microbiology. AI/scoring system may have a role to play in the diagnosis of bacterial vs viral TP, and in doing so may enable more appropriate antibiotic usage targeted to only bacterial TP infections. It is important to distinguish between bacterial and viral tonsillopharyngitis in the COVID-19 pandemic.","PeriodicalId":402691,"journal":{"name":"Interdisciplinary Medical Journal","volume":"76 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2023-12-04","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"139186984","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"The relationship between age and mortality and morbidity of patients diagnosed with breast cancer: a retrospective clinical study","authors":"M. Dal, M. Temiz","doi":"10.17944/interdiscip.1379579","DOIUrl":"https://doi.org/10.17944/interdiscip.1379579","url":null,"abstract":"Objective: Breast cancer, the most common malignancy among women, is a universally challenging health problem. It is a known fact that the incidence of breast cancer increases with age. In addition, mortality and morbidity increase with age. For now, it does not seem possible to reduce the incidence of breast cancer but it is possible to limit deaths caused by it. Patients are encouraged to get early diagnosis and age-appropriate screening tests. Because regular screening and early diagnosis are very important in improving breast cancer outcomes. Factors such as age, hormonal status and genetics are associated with the incidence of breast cancer. In this study, we aimed to contribute to the literature by examining age-related mortality and morbidity of breast cancer. Method: This study was carried out at a University Hospital. The sample consisted of 214 women between 01.09.2018/01.09.2022 diagnosed with breast cancer, aged 30 to 80 years. Results: The mean age of women was 51.9 ± 7.6 years, with 52.8% being","PeriodicalId":402691,"journal":{"name":"Interdisciplinary Medical Journal","volume":"28 2","pages":""},"PeriodicalIF":0.0,"publicationDate":"2023-12-03","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"139187247","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Prevalance of impaired glucose tolerance and its association with adverse perinatal outcomes in non-gestational diabetes pregnancies","authors":"A. Usta, M. Hocaoğlu, Cagla Bulbul, C. Usta","doi":"10.17944/interdiscip.1347548","DOIUrl":"https://doi.org/10.17944/interdiscip.1347548","url":null,"abstract":"Objective: Gestational diabetes mellitus (GDM) is characterized by glucose intolerance with onset during pregnancy and is one of the most common metabolic disorders complicating pregnancy. The aim of this study was to evaluate the risk of maternal and neonatal outcomes in non-gestational diabetes pregnancies with abnormal glucose challenge test (GCT) and abnormal glucose tolerance test (GTT) results. Methods: In this retrospective cohort study of 2982 singleton pregnancies, all patients underwent a non-fasting 50 g GCT at 24 to 28 weeks of gestation. A GCT cutoff of ≥ 140 mg/dl was selected. Women with an elevated GCT underwent prompt diagnostic testing with a 3-hour GTT. Subjects were divided into four groups according to GCT and GTT results. Results: There was an impaired glucose tolerance in 19.2 % of patients and 14.7 % of them had mild glucose intolerance and 4.5 % of them had moderate glucose intolerance. As expected, there was statistically significant difference in fetal macrosomia, neonatal hypoglicemia, PE, primary CS, and preterm birth between secreening negative and GDM patients (p < 0.0001). We also observed statistically significant difference in neonatal hypoglicemia (p = 0.0001) and PE (p = 0.0277) between screning negative and mild glucose intolerance group. Moreover, there was a significant difference in fetal macrosomia (p=0.0480) between mild glucose intolerance and moderate glucose intolerance groups. Conclusion: Compared with screening negative group, mild and moderate glucose intolerance are associated with increased adverse maternal and neonatal outcomes even in the absence of GDM.","PeriodicalId":402691,"journal":{"name":"Interdisciplinary Medical Journal","volume":"468 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2023-11-24","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"139240448","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Vena cava inferior agenesis recognized by incidentally in a patient under cholecystectomy","authors":"Kevser Tural","doi":"10.17944/interdiscip.1335531","DOIUrl":"https://doi.org/10.17944/interdiscip.1335531","url":null,"abstract":"Inferior Vena cava (IVC) agenesis is a rare congenital anomaly, which may cause significant consequences with regard to morbidity and mortality. In this case report, a patient diagnosed with IVC agenesis which was seen intraabdominal intensive venous collateral during surgery for cholecystectomy is presented.","PeriodicalId":402691,"journal":{"name":"Interdisciplinary Medical Journal","volume":"24 4","pages":""},"PeriodicalIF":0.0,"publicationDate":"2023-11-10","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"139280326","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"The effect of obesity on oxidative stress parameters in pregnant women","authors":"Derya KOCAMAZ, Gülizar ATLI, Şule MENZİLETOĞLU YILDIZ, Sefa ARLIER, Birol GÜVENÇ","doi":"10.17944/interdiscip.1344660","DOIUrl":"https://doi.org/10.17944/interdiscip.1344660","url":null,"abstract":"Objective: In recent years, there has been a growing concern about obesity in public since it is known to reduce fertility in women and increase the duration of conception. Maternal obesity is also related to adverse pregnancy outcomes affected by placental malfunction. Therefore, in this study, we aimed to compare levels of oxidative stress between obese and normal weight women in the second trimester.
 Method: We assessed lipid peroxidation by measuring the thiobarbituric acid reactive species (TBARS) as well as antioxidant defense system by measuring the activity of superoxide dismutase (SOD), glutathione peroxidase (GPx) and catalase (CAT) enzymes in 50 obese women (body mass index, BMI:36.60±4.95) and 51 normal weight women (BMI:24.51±3.47).
 Results: An increased lipid peroxidation and SOD enzyme activity were determined in obese pregnant women compared to normal weight women. Also, we found a significantly positive correlation (r:0.286, p:0.0435) between BMI and TBARS level as well as a significantly negative correlation (r: -0.421, p: 0.002) between TBARS level and SOD enzyme activity. No significance difference was observed between two groups in CAT and GPx enzymes activities.
 Conclusion: According to our results, although increased SOD enzyme activity has reflected that antioxidant defense system is activated cope with the increased production of reactive oxygen species, maternal obesity is induced oxidative stress via increased lipid peroxidation. Hence, maternal obesity induced-oxidative stress in the second trimester should be followed up by clinicians since it may cause oxidative damage in the placenta during pregnancy.","PeriodicalId":402691,"journal":{"name":"Interdisciplinary Medical Journal","volume":"11 2","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2023-10-27","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"136312566","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Adil Haci̇boncuk, Alper Aytekin, Latif Yılmaz, Nurullah Bi̇len, Aziz Bulut
{"title":"Can the risk of hypocalcemia be detected with intact parathyroid hormone level after total thyroidectomy?","authors":"Adil Haci̇boncuk, Alper Aytekin, Latif Yılmaz, Nurullah Bi̇len, Aziz Bulut","doi":"10.17944/interdiscip.1410405","DOIUrl":"https://doi.org/10.17944/interdiscip.1410405","url":null,"abstract":"Objective: Nowadays, thyroidectomy is performed in patients with various indications. However, transient or permanent hypocalcemia occurs after surgery. In this case, the duration of hospitalization of the patients is prolonged. In this study, we aimed to detect hypocalcemia in the early phase with intact parathyroid hormone (iPTH), a biochemical marker. Method: Hospital records of patients who had undergone standard bilateral total thyroidectomy for thyroid disease were retrospectively analyzed between September 2018 and April 2019 at the Department of General Surgery, Gaziantep University. Results: Of the 114 patients included in the study, 91 were female (79.8%), and 23 were male (23%). Calcium levels of ≤8.5 mg/dL were found in 49 of 114 patients. Clinical symptoms of hypocalcemia were observed in 19 of these 49 patients. There was a significant correlation between the patients’ iPTH levels at 3-6 hours postoperatively and the calcium values at 24 hours postoperatively (p","PeriodicalId":402691,"journal":{"name":"Interdisciplinary Medical Journal","volume":"91 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2023-10-26","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"139313663","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Eser Ördek, İ. Albayrak, Muhammed Nur Karadeni̇z, B. Kati
{"title":"A rare malignity observed in the appearance of angiomyolipoma; tubulocystic renal cell carcinoma after partial nephrectomy","authors":"Eser Ördek, İ. Albayrak, Muhammed Nur Karadeni̇z, B. Kati","doi":"10.17944/interdiscip.1410378","DOIUrl":"https://doi.org/10.17944/interdiscip.1410378","url":null,"abstract":"Cystic neoplasms of the kidney are quite rare. Because they contain various differential diagnoses and their radiological features are not specific, their diagnosis is very difficult except for histopathological data. Usually, they can be confused radiologically with benign cysts of the kidney or angiomyolipoma. Radical or partial nephrectomy is the most commonly preferred curative treatment method when it shows features like rapidly growing or malignancy. Histopathological examination is required for definitive diagnosis. In this article, we aimed to present a rare case of tubulocystic renal cell carcinoma after partial nephrectomy in our clinic, who was followed up in another center for years with the pre-diagnosis of angiomyolipoma, in the light of the literature.","PeriodicalId":402691,"journal":{"name":"Interdisciplinary Medical Journal","volume":"281 1 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2023-10-26","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"139313740","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Emre Öteyaka, Gizem Sari, Mehmet Turan Basunlu, O. Kuguoglu, Y. Yozgat, Abdullah Erdem, Murat Uğurlucan, Halil Türkoğlu
{"title":"Modified Konno Procedure for left ventricular outflow tract obstruction: report of two cases","authors":"Emre Öteyaka, Gizem Sari, Mehmet Turan Basunlu, O. Kuguoglu, Y. Yozgat, Abdullah Erdem, Murat Uğurlucan, Halil Türkoğlu","doi":"10.17944/interdiscip.1410429","DOIUrl":"https://doi.org/10.17944/interdiscip.1410429","url":null,"abstract":"Left ventricular outflow tract obstruction with a systolic anterior motion of the mitral valve is a challenging pathology. An intervention, either surgically or with a percutaneous technique is taken into consideration when the pressure gradient reaches critical levels. Subaortic myectomy is still the gold standard treatment modality in these particular patients. Modified Konno procedure may be added to the procedure when a significant gradient persists following subaortic resection, because of its association with increased outflow tract obstruction relief. We herein present our experiences with two cases that underwent modified Konno procedures for the treatment of hypertrophic obstructive cardiomyopathy.","PeriodicalId":402691,"journal":{"name":"Interdisciplinary Medical Journal","volume":"1 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2023-10-24","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"139314551","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}