Polski Merkuriusz Lekarski最新文献

{"title":"Dehumanization and attitudes toward LGBTQ individuals among primary healthcare nurses: The role of personality traits and LGBTQ health knowledge.","authors":"Vissarion Bakalis, Aikaterini Toska, Stella Zetta, Foteini Malli, Maria Saridi, Sofia Zyga, Krysatlia Gkouletsa, Evangelos C Fradelos","doi":"10.36740/Merkur202502112","DOIUrl":"https://doi.org/10.36740/Merkur202502112","url":null,"abstract":"<p><strong>Objective: </strong>Aim: This study investigates dehumanization and attitudes toward LGBTQ+ individuals among primary healthcare nurses in Greece, exploring the influence of personality traits, empathy, and LGBTQ+ health knowledge.</p><p><strong>Patients and methods: </strong>Materials and Methods: A cross-sectional design was used with 114 public-sector primary healthcare nurses completing self-report questionnaires between July and October 2023. Instruments included a culturally adapted dehumanization scale, the Ten-Item Personality Inventory, and the Toronto Empathy Questionnaire. Statistical analysis included Mann-Whitney and Kruskal-Wallis tests, Spearman's correlations, and linear regression.</p><p><strong>Results: </strong>Results: The sample was predominantly female (74.6%), heterosexual (93.9%), and Christian Orthodox (93%). Only 8.8% had attended LGBTQ+ healthcare courses, and 33.3% had cared for LGBTQ+ patients. Mechanistic dehumanization showed limited associations with personality traits, while animalistic dehumanization was negatively correlated with willingness to care (r = -0.441, p < 0.001) and comfort with LGBTQ+ care (r = -0.391, p < 0.001). Empathy and openness to experience influenced attitudes and willingness to care. Higher empathy unexpectedly reduced willingness to care, while emotional stability and conscientiousness predicted dehumanization.</p><p><strong>Conclusion: </strong>Conclusions: Findings highlight a moderate dehumanization trend among nurses, affecting LGBTQ+ patients' care quality. Educational initiatives targeting LGBTQ+ health knowledge, empathy training, and the influence of personality traits are critical to fostering inclusive care and reducing dehumanization in healthcare settings.</p>","PeriodicalId":39518,"journal":{"name":"Polski Merkuriusz Lekarski","volume":"53 2","pages":"229-238"},"PeriodicalIF":0.0,"publicationDate":"2025-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144054112","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Effect of apelin level in Iraqi diabetic women with hypothyroidism.","authors":"Maryam Qusay Isaa, Noor Thair Tahir","doi":"10.36740/Merkur202502110","DOIUrl":"https://doi.org/10.36740/Merkur202502110","url":null,"abstract":"<p><strong>Objective: </strong>Aim: To determine how Apelin levels and other biochemical markers affect thyroid function of Iraqi diabetic women.</p><p><strong>Patients and methods: </strong>Materials and Methods: 88 subjects participated in this study, 44 diabetic women with hypothyroidism, whose ages between 40 and 60 years, and 44 healthy as a control group, whose ages between 40 and 55 years, during December 2022 to the end of April 2023. Demographic characters such as age, height, and weight of all participants were noted. Serum thyroxin, triiodothyronine and thyroid stimulating hormone were measured by Minivans with Biomerix Kits. Fasting serum glucose, glycated hemoglobin (HbA1c), lipid profile (total cholesterol, triglyceride, high density lipoprotein, and low-density lipoprotein, and very low-density lipoprotein), blood urea, and serum creatinine were among the tests performed on blood samples for the laboratory research. ELISA kit was used to measure amount of apelin.</p><p><strong>Results: </strong>Results: A highly significant increase of apelin levels in diabetic women with hypothyroidism when compared with control, a significant positive correlation P <0.05 between Apelin level and each of: weight, body mass index, TSH, glycated hemoglobin (HbA1c), TG and VLDL and shows a highly significant positive correlation P<0.05 between Apelin level vs. TT4, FBS, TC and LDL. A significant negative correlation P<0.05 was found between Apelin levels vs. serum HDL in diabetic women with hypothyroidism.</p><p><strong>Conclusion: </strong>Conclusions: A significant increase in results of Apelin in women with hypothyroidism and diabetes led to a significant imbalance in lipid metabolism, in the future, this might be an indicator of their risk of heart disease.</p>","PeriodicalId":39518,"journal":{"name":"Polski Merkuriusz Lekarski","volume":"53 2","pages":"218-221"},"PeriodicalIF":0.0,"publicationDate":"2025-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144052561","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Estimation of plasma TGF-β1 after intra-articular platelet rich plasma injection in-patient with anterior disc displacement with intermittent locking of TMJ disorder.","authors":"Karar Abdulzahra Mahdi, Muhassad H Al-Mudhafar, Dunya Malhan Hanweet","doi":"10.36740/Merkur202502101","DOIUrl":"https://doi.org/10.36740/Merkur202502101","url":null,"abstract":"<p><strong>Objective: </strong>Aim: To evaluate plasma levels of TGF-β1 and the clinical impact of platelet-rich plasma injections on mandibular opening and pain in patients with anterior disc displacement and intermittent locking.</p><p><strong>Patients and methods: </strong>Materials and Methods: Twenty-seven temporomandibular disorder patients, diagnosed by oral medicine specialists, received three intra-articular PRP injections over three months, with evaluations conducted two weeks after the final injection. Plasma TGF-β1 levels were measured before and after treatment, with visual analog scale pain scores and mouth opening measurements.</p><p><strong>Results: </strong>Results: Results showed that the mean plasma TGF-β1 level in temporomandibular disorder patients increased significantly from (312.6 pg/ml ± 67.96) before PRP injection to (400.4 pg/ml± 108.51) after PRP injection. Platelet-rich plasma-treated patients also experienced a significant reduction in Visual Analogue Scale scores, which decreased from (6.21 ± 0.95) to (0.78 ± 0.79), with improved range of mouth opening after PRP injection.</p><p><strong>Conclusion: </strong>Conclusions: Intra-articular platelet-rich plasma injections effectively increased plasma TGF-β1 levels, reduced pain intensity, and improved mandibular opening range in temporomandibular disorder patients.</p>","PeriodicalId":39518,"journal":{"name":"Polski Merkuriusz Lekarski","volume":"53 2","pages":"179-183"},"PeriodicalIF":0.0,"publicationDate":"2025-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144049507","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Use of amniotic membranes in dentistry - literature review.","authors":"Justyna Talaska, Wojciech Niemczyk, Karol Demel, Ali Aboud, Monika Dziedzic, Jakub Król, Kaja Zawadzka, Anna Zawilska","doi":"10.36740/Merkur202501116","DOIUrl":"10.36740/Merkur202501116","url":null,"abstract":"<p><p>The amniotic membrane, which lacks blood vessels, lymphatic vessels and nerves, is a thin membrane with anti-inflammatory and anti-scarring properties. In the field of dentistry, it is primarily employed as a dressing following the removal of malignant or pre-malignant lesions, with the objective of ensuring haemostasis and the absence of allergic reactions. Furthermore, it is employed in the treatment of oro-auricular junctions, cleft palates and in guided bone regeneration, due to the presence of mesenchymal cells. In vestibuloplasty, it has been demonstrated to enhance vestibular deepening, accelerate epithelialisation and reduce pain. In periodontics, it has been shown to be an effective treatment for gingival recession and furcation defects, and to increase the width of keratinised gingiva around implants. In endodontics, it is employed in regenerative procedures, offering comparable results to standard methods. Furthermore, in the treatment of osteoarthritis of the temporomandibular joint, it has been observed to provide pain relief and improved joint function.</p>","PeriodicalId":39518,"journal":{"name":"Polski Merkuriusz Lekarski","volume":"53 1","pages":"115-119"},"PeriodicalIF":0.0,"publicationDate":"2025-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143597967","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Atrial fibrillation in non-ST-elevation myocardial infarction patients - worse clinical presentation and adverse long term prognosis.","authors":"Marcin Kamil Dobrowolski, Ilona Kowalik, Krzysztof Jaworski, Michał Farkowski, Rafał Dąbrowski","doi":"10.36740/Merkur202501104","DOIUrl":"10.36740/Merkur202501104","url":null,"abstract":"<p><strong>Objective: </strong>. Aim: The aim of this ambispective, two-center, observational study was to evaluate the clinical characteristics and 3-years prognosis of patients with non-STelevation myocardial infarction (NSTEMI) and AF.</p><p><strong>Patients and methods: </strong>Materials and methods: Patients hospitalized with a diagnosis of NSTEMI were included. Baseline demographic and clinical features, in-hospital procedures, and occurrence of cardiovascular events in patients with sinus rhythm (SR) and AF confirmed before admission were analyzed.</p><p><strong>Results: </strong>Results: A total of 273 patients with NSTEMI were enrolled between 2012 and 2015, of whom 102 had AF (37.3%, 60.8% men) and 171 had SR (64.3% men). Patients with AF and NSTEMI were significantly older: 76.6±8.4 vs. 65.9±11.1 years (p<0.0001). The permanent pattern of AF was observed in 54 patients (52.9%) and paroxysmal in 48 patients (47.1%). They more often had heart failure with higher NYHA class (p<0.0001), type 2 diabetes (p=0.0001), abnormal renal function (p<0.0001), and history of stroke (p<0.0001). The presence of AF was not correlated with the number of stenotic coronary vessels. Significantly more NSTEMI patients with AF had a pacemaker implanted before admission (p<0.0001). Duration of hospital stay of NSTEMI AF patients was longer: 10.5±9.9 vs.6.6±4.2 days and it was related to age, Rho=0.5,p=0.0002. During the 2-year and 3-year follow-ups, AF was significantly related to higher mortality, both cardiovascular disease and all-cause mortality (p<0.0001). Independent long-term all-cause mortality predictors were heart failure, liver insufficiency, and age. At the 3-years follow-up, there were no significant differences in all-cause and cardiovascular mortality between groups with permanent AF and paroxysmal AF (p=0.696).</p><p><strong>Conclusion: </strong>Conclusions: Patients with atrial fibrillation and NSTEMI were older and more likely to have comorbidities. During the 2-year and 3-year follow-ups, AF was related significantly to higher mortality, both cardiovascular and of all causes. The long-term prognosis of patients with AF was adversely affected by heart failure, liver insufficiency and age.</p>","PeriodicalId":39518,"journal":{"name":"Polski Merkuriusz Lekarski","volume":"53 1","pages":"26-33"},"PeriodicalIF":0.0,"publicationDate":"2025-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143598074","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Applications of magnetic resonance imaging in the diagnosis of posttraumatic stress disorder.","authors":"Barbara Paraniak-Gieszczyk","doi":"10.36740/Merkur202502117","DOIUrl":"https://doi.org/10.36740/Merkur202502117","url":null,"abstract":"<p><p>The application of magnetic resonance imaging (MRI) techniques in diagnosing posttraumatic stress disorder (PTSD) represents a significant research focus, providing deeper insights into trauma-related psychological disorders. PTSD often arises from chronic stress, a state in which the body struggles to adapt to overwhelming stimuli. Patients frequently experience persistent flashbacks (intrusive memories or sensory recollections of the traumatic event) and nightmares, which evoke intense emotional responses and disrupt daily life. These recurring episodes of stress and anxiety severely impact behavior and functioning. Understanding the brain changes associated with PTSD has become possible through advancements in MRI studies. This article aims to review the scientific literature on the use of magnetic resonance imaging techniques in diagnosing posttraumatic stress disorder. The review is based on scientific literature from medical databases, including Web of Science and Scopus, covering publications up to October 30, 2024. The findings from this analysis may contribute to a better understanding of the neurobiological mechanisms underlying PTSD.</p>","PeriodicalId":39518,"journal":{"name":"Polski Merkuriusz Lekarski","volume":"53 2","pages":"273-276"},"PeriodicalIF":0.0,"publicationDate":"2025-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144052678","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Subspecies typing on the example of klebsiella pneumoniae isolated from patients with pulmonary tuberculosis.","authors":"Nurlan Tabriz, Zhanara Nurtazina, Alyona Lavrinenko, Zhumat Mutayhan, Altynay Taishykova","doi":"10.36740/Merkur202501109","DOIUrl":"10.36740/Merkur202501109","url":null,"abstract":"<p><strong>Objective: </strong>Aim: The purpose of this study was to evaluate sub-species typing by matrix-activated laser desorption/ionisation mass spectrometry on the example of Klebsiella pneumoniae isolated from patients with pulmonary tuberculosis in Karaganda region..</p><p><strong>Patients and methods: </strong>Materials and Methods: This study evaluated the potential of MALDI-TOF MS for epidemiological identification of Klebsiella pneumoniae isolated from pulmonary tuberculosis patients in Karaganda region. A total of 47 strains of Klebsiella pneumoniae obtained between 2015 and 2019 were typed. Mass spectra were taken using Microflex LT MALDI-TOF (Bruker) according to standard procedure.</p><p><strong>Results: </strong>Results: As a result, MALDI-TOF evaluation of subspecies typing on the example of Klebsiella pneumoniae isolated from patients with pulmonary tuberculosis in Karaganda region, predominantly showed the diversity of isolates, indicating their out-of-hospital nature. Based on all available information, including facts, sources, and experimental results, it can be reasonably concluded that the current study of Klebsiella pneumoniae does not provide a complete picture of the epidemiology of this microorganism.</p><p><strong>Conclusion: </strong>Conclusions: The current study provided a limited opportunity to investigate the genetic structure and diversity of Klebsiella pneumoniae subspecies more accurately. The findings suggest that the time-of-flight laser-ionisation ablation mass spectrometry method with magnetic focusing is more likely to detect differences in external characteristics between individual specimens of the same species than internal genetic variation in the microorganisms under study. The practical relevance of this study is to inform the development of more effective infection control strategies in clinical practice and infection control.</p>","PeriodicalId":39518,"journal":{"name":"Polski Merkuriusz Lekarski","volume":"53 1","pages":"67-74"},"PeriodicalIF":0.0,"publicationDate":"2025-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143597856","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Painful shoulder syndrome as a clinical problem - analysis of physical therapy.","authors":"Włodzisław Kuliński, Krystian Szymczyk","doi":"10.36740/Merkur202502103","DOIUrl":"https://doi.org/10.36740/Merkur202502103","url":null,"abstract":"<p><strong>Objective: </strong>Aim: The aim of this paper is to assess the efficacy of physical therapy conducted in patients with painful shoulder syndrome in the course of rotator cuff injury.</p><p><strong>Patients and methods: </strong>Materials and Methods: The study involved a group of 25 patients: 15 women and 10 men. The patients were treated at a rehabilitation clinic in Radom for a period of 3 weeks. The physical therapy used in study patients included diadynamic currents, ultrasound therapy, cryotherapy, shockwave therapy, and kinesiotherapy.</p><p><strong>Results: </strong>Results: After treatment, the pain was eliminated or remarkably reduced and the range of joint motion was increased in all planes.</p><p><strong>Conclusion: </strong>Conclusions: 1. The physical therapy used in study patients helped eliminate or reduce pain. 2. The range of joint motion was increased in all planes. 3. The quality of life and functioning in study patients was improved. 4. Treatment of this disorder is based on physical therapy.</p>","PeriodicalId":39518,"journal":{"name":"Polski Merkuriusz Lekarski","volume":"53 2","pages":"166-173"},"PeriodicalIF":0.0,"publicationDate":"2025-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144048972","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Evaluation of the patient-centric principle in the organization of medical care and prevention of open-angle glaucoma progression.","authors":"Volodymyr O Melnyk, Borys I Palamar","doi":"10.36740/Merkur202502107","DOIUrl":"https://doi.org/10.36740/Merkur202502107","url":null,"abstract":"<p><strong>Objective: </strong>Aim: To investigate the patient-centred principle in preventing and providing medical care for open-angle glaucoma.</p><p><strong>Patients and methods: </strong>Materials and Methods: A systematic approach was implemented using a comprehensive set of methods. A self-developed questionnaire was used to collect data. The patient survey was conducted from 1 May 2024 to 30 August 2024. A targeted selection of respondents who underwent surgical treatment for primary open-angle glaucoma from all regions of Ukraine was applied using the main array method (N = 1000).</p><p><strong>Results: </strong>Results: The study revealed that satisfaction with ophthalmological care was expressed by more than 90% ± 0.95% of respondents (rate per 100 respondents ± standard error). A hereditary predisposition to glaucoma was identified in 20% ± 1.26% of respondents. In more than 80% ± 1.26% of cases, glaucoma was detected by an ophthalmologist, while in more than 17% ± 1.88% of cases, it was identified by a family doctor.</p><p><strong>Conclusion: </strong>Conclusions: In order to defect glaucoma early and monitor the progression of the disease, there is a need for informational and methodological work with primary care doctors, implementation of algorithms for preventive examinations of patients. Patient awareness regarding the safety and effectiveness of glaucoma surgery affects the timeliness of surgical intervention and vision preservation.</p>","PeriodicalId":39518,"journal":{"name":"Polski Merkuriusz Lekarski","volume":"53 2","pages":"191-202"},"PeriodicalIF":0.0,"publicationDate":"2025-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144019588","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"The prediction power of thymidine phosphorylase and IL-6 in the relapse of breast cancer.","authors":"Ahmed Hussein Zwamel, Hind Mizhir Mousa, Bushra A M Abdul Azeez, Ali A Al-Fahham","doi":"10.36740/Merkur202501112","DOIUrl":"10.36740/Merkur202501112","url":null,"abstract":"<p><strong>Objective: </strong>Aim: To investigate the role of thymidine phosphate and IL-6 in the pathogenesis and survival rate in women with breast cancer..</p><p><strong>Patients and methods: </strong>Materials and Methods: Sixty women diagnosed with breast cancer (with age ranging between 25-65 years) were included in the current study. Of these, 40 women relapse after 6 months of follow up, while 40 patients were non-relapsed.</p><p><strong>Results: </strong>Results: Statistical analysis pointed out that thymidine phosphorylase may be significantly increased in relapsed women comparing to non-relapsed women (4.48±0.24 ng/ml and 1.12±0.18 ng/ml respectively, p value <0.0001). Regarding IL-6, the current study also found that IL-6 tends to be increased in relapse BC comparing to non-relapsed BC (8.6±0.92 pg/ml vs. 6.82±1.14 pg/ml respectively, p-value<0.0001. There was a high significant positive correlation between thymidine phosphorylase and IL-6 (r=0.368; p-value <0.01). The sensitivity and specificity in predicting relapse in breast cancer were 0.83 and 0.64 for TP and 0.78, and 0.65 respectively.</p><p><strong>Conclusion: </strong>Conclusions: It is suggested that thymidine phosphate activity and IL-6 serum levels after six months of follow up, have a dual synergistic impact on the pathogenesis of relapse for BC. These biomarkers can also be used in the prediction of relapse rate in women diagnosed with BC.</p>","PeriodicalId":39518,"journal":{"name":"Polski Merkuriusz Lekarski","volume":"53 1","pages":"88-93"},"PeriodicalIF":0.0,"publicationDate":"2025-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143597895","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}