Medical Journal of Malaysia最新文献

{"title":"Knowledge and attitude of basic cardiopulmonary resuscitation among home-based child daycare caregivers in Kelantan.","authors":"A R Abdullah, M F Mohd Shukri, A S Sjahid, M A Abu Bakar, N Yaacob, M H Fauzi","doi":"","DOIUrl":"","url":null,"abstract":"<p><strong>Introduction: </strong>Cardiopulmonary resuscitation (CPR) is indeed a basic skill that should be acquired by everyone in the community. Early CPR is an important element in the chain of survival and home-based child daycare (HBCD) caregivers play a vital role as early responders in case of out-of-hospital cardiac arrest (OHCA). The study aims to determine the level of knowledge and attitude of CPR among HBCD caregivers in Kelantan and the factors that contribute to them. This study covers a research gap in Kelantan, Malaysia, evaluating HBCD caregivers' knowledge and attitudes towards CPR.</p><p><strong>Materials and methods: </strong>This was a quantitative crosssectional study conducted from November 2020 until March 2021 which involves 139 HBCD caregivers in Kelantan. Validated questionnaire was used which consisted of 27 questions based on demography, knowledge and attitude towards CPR. The data was keyed in and analysed using software SPSS version 26.</p><p><strong>Results: </strong>A total of 139 respondents participated in the study. The mean attitude score obtained by the caregivers was 16.67 with SD = 4.22. There were 89 caregivers (64%) with poor knowledge among the 139 HBCD caregivers in the study compared to 50 HBCD caregivers (36%) who had good knowledge. Caregivers who were exposed with CPR training had 5.91 higher odds of having good CPR knowledge compared to those without being exposed to CPR training (Wald-statistic (df) = 21.12 (1), OR (95% CI) = 5.91 (2.77, 12.61), p<0.001). Caregivers with experience in handling CPR were 5.91 of higher odds in having good CPR knowledge compared to those without the experience in handling CPR when adjusted for the duration of caregiver's experience (Wald-statistic (df) = 21.12 (1), OR (95% CI) = 5.91 (2.77, 12.61), p<0.001). HBCD caregivers' experience was the only variable that had a significant p-value when tested in the regression model (p = 0.023).</p><p><strong>Conclusion: </strong>The findings revealed that HBCD caregivers in Kelantan had inadequate CPR knowledge, potentially increasing the risk of OHCA. Planned and regular training for them is mandatory. Exposure to CPR was the associated factor that contributes to knowledge level among HBCD caregivers whereas years of experience as HBCD caregivers influence attitude towards CPR.</p>","PeriodicalId":39388,"journal":{"name":"Medical Journal of Malaysia","volume":"80 2","pages":"199-205"},"PeriodicalIF":0.0,"publicationDate":"2025-03-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143721869","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Evaluation of choroidal thickness in Malay children with myopia.","authors":"M Nurul-Farhana, N F Ngah, I Shatriah","doi":"","DOIUrl":"","url":null,"abstract":"<p><strong>Introduction: </strong>This study aims to evaluate the choroidal thickness and its correlation with age, spherical equivalent, and axial length in Malay children with myopia, addressing the limited data available on this topic in Southeast Asia.</p><p><strong>Material and methods: </strong>A cross-sectional, hospital-based study was conducted from 2022 to 2024 at Hospital Shah Alam and Hospital Pakar Universiti Sains Malaysia. A total of 109 Malay children aged 7-17 years participated, including 88 with myopia and 21 with emmetropia. Each participant underwent a comprehensive ocular examination, including non-cycloplegic refraction and axial length measurement. Choroidal thickness was assessed using Cirrus SD-optical coherence tomography, with one eye from each subject randomly selected for analysis.</p><p><strong>Results: </strong>The mean subfoveal choroidal thickness was significantly thinner in myopic children (284.91 μm) compared to emmetropic children (347.62 μm) (p<0.001). Additionally, choroidal thickness varied significantly with the degree of myopia: mild myopia had a mean subfoveal thickness of 319.69 μm, moderate myopia 290.04 μm, and high myopia 225.72 μm, with high myopia showing the thinnest choroid (p<0.001). A significant negative correlation was observed between axial length and subfoveal choroidal thickness, while a positive correlation was found between spherical equivalent and choroidal thickness. No significant correlation was identified between age and subfoveal choroidal thickness.</p><p><strong>Conclusion: </strong>Malay children with myopia exhibit a thinner mean choroidal layer compared to their emmetropic peers, with the thinnest choroid observed in cases of high myopia. This indicates that thinning of the choroidal vasculature occurs with the increase in axial length and worsening severity of myopia.</p>","PeriodicalId":39388,"journal":{"name":"Medical Journal of Malaysia","volume":"80 2","pages":"221-227"},"PeriodicalIF":0.0,"publicationDate":"2025-03-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143721840","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Usability and functionality of M-DFEET application for the independence of foot care in diabetes mellitus patients.","authors":"N L P I B Agustini, N P A R Dewi, K A N Putra, W E Sanjana","doi":"","DOIUrl":"","url":null,"abstract":"<p><strong>Introduction: </strong>Diabetes mellitus (DM) poses significant challenges in foot care management, often leading to severe complications if not properly addressed. Diabetic Peripheral Neuropathy (PND) is commonly associated with diabetic foot ulcer (DFU) and is a leading cause of hospital admissions and prolonged treatment durations. Therefore, this study aimed to determine the usability and functionality of the Mobile Diabetic Foot Early Self-Assessment (MDFEET) application for the independence of foot care for DM patients in the South Denpasar Community Health Centre area.</p><p><strong>Materials and methods: </strong>This is a cross-sectional study with 60 DM patients, selected by simple random sampling. The instrument used consists of the DM patient observation sheet-based user view and the M-DFEET application. Categorical data were classified as frequency and percentage, while the numerical data were reported as mean and standard deviation (SD).</p><p><strong>Results: </strong>The evaluation results show that all 60 participants (100%) rated the functionality of the M-DFEET application as excellent in helping with foot care. Furthermore, most participants, 55 (91.7%), assessed the efficiency of the application as good. Regarding the usability, 58 participants (96.7%) considered it good, while the remaining participants deemed it adequate. These findings underscore the application's potential to optimize time and effort for its users effectively.</p><p><strong>Conclusions: </strong>The feedback on the M-DFEET application is overwhelmingly positive, with all participants rating its functionality as very good for foot care. The application is likely to be well-received by users especially T2DM patients, and holds potential as an evaluative tool in foot care management.</p>","PeriodicalId":39388,"journal":{"name":"Medical Journal of Malaysia","volume":"80 2","pages":"178-182"},"PeriodicalIF":0.0,"publicationDate":"2025-03-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143721647","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Identifying predictors of worsening glycaemic outcomes in prediabetes: a two-year cohort study in Terengganu, Malaysia.","authors":"N A Yusof, N A Idris, A Abdul Aziz, N N Naing, S S Oo, M M T Aung, M Z H Ismail, R Abdul Latif","doi":"","DOIUrl":"","url":null,"abstract":"<p><strong>Introduction: </strong>Prediabetes is a critical stage preceding diabetes mellitus (DM) which is also associated with an elevated risk of developing DM and related complications. Addressing predictors that influence the progression or regression of glycaemic outcomes in prediabetic individuals can enhance intervention strategies. This study aims to identify key predictors of glycaemic progression among adults with prediabetes in Terengganu, Malaysia.</p><p><strong>Materials and methods: </strong>A retrospective cohort study was conducted involving 592 prediabetic adults from 28 health clinics in Terengganu between January 2019 and June 2023. Participants were selected based on oral glucose tolerance test (OGTT) results indicating prediabetes. Sociodemographic, medical background, and clinical data, including body mass index (BMI), blood pressure, fasting blood sugar (FBS), and lipid profiles, were extracted from medical records. Glycaemic outcomes were classified into three categories: reversion to normoglyacemia, persistent prediabetes, or progression to DM, based on glycated haemoglobin (HbA1c) levels taken within two years of follow-up. Ordinal logistic regression analysis was used to identify the significant predictors influencing these outcomes.</p><p><strong>Results: </strong>Analysis showed age, BMI, underlying dyslipidaemia, FBS, and triglyceride levels as significant predictors of glycaemic progression. Specifically, each additional year of age and each one-unit increase in BMI raised the likelihood of progression to DM by 3% and 6%, respectively. Participants with dyslipidaemia were noted to have a 67% higher risk of worsening glycaemic status, while increases in FBS and triglyceride levels were associated with 65% and 34% greater odds of diabetic progression, respectively.</p><p><strong>Conclusion: </strong>This study identifies critical predictors of glycaemic outcomes in prediabetic adults, emphasizing the role of age, BMI, dyslipidaemia, FBS, and triglycerides in the disease progression. These findings support the development of targeted interventions that address these risk factors to curb diabetes progression in high-risk individuals, contributing valuable insights into diabetes prevention strategies tailored for Malaysian populations.</p>","PeriodicalId":39388,"journal":{"name":"Medical Journal of Malaysia","volume":"80 2","pages":"212-220"},"PeriodicalIF":0.0,"publicationDate":"2025-03-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143721851","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Uterine torsion in pregnancy: a case report and systematic review.","authors":"A Z Zahar, M A Mazrin Nur","doi":"","DOIUrl":"","url":null,"abstract":"<p><strong>Introduction: </strong>Uterine torsion in pregnancy is a rare condition but is associated with significant negative outcomes to the pregnant women and their babies. This study is to systematically review the literatures and analyse the clinical presentations, management and complications of uterine torsion in pregnancy.</p><p><strong>Materials and methods: </strong>We searched across multiple databases (PubMed, Google Scholar, ScienceDirect, Academia.edu, ResearchGate and Semantic Scholar) and suitable articles from 1993 to 2022 were systematically chosen according to PRISMA guideline. The analysis was performed on the maternal characteristics, signs and symptoms of the uterine torsion, management, complications and outcomes of both the mothers and infants. All case reports or case series reporting uterine torsion in pregnancy from English language journals were included without restriction on the geographical origin.</p><p><strong>Results: </strong>A total of 149 cases from 146 publications and one from our centre were included for analysis. Most of the cases were seen in the third trimester and presented with acute abdominal symptoms and signs. It presented a challenge in diagnosis and had a myriad of complications to the mothers and infants. The maternal mortality is 2.0% while the perinatal mortality stands at 38.2%.</p><p><strong>Conclusion: </strong>Uterine torsion in pregnancy is a rarely encountered but serious condition with no specific precipitating factor or diagnostic criteria. It can occur at any gestation, has a wide range of non-specific clinical presentations, and carries a significant risk to the mother and child.</p>","PeriodicalId":39388,"journal":{"name":"Medical Journal of Malaysia","volume":"80 2","pages":"245-257"},"PeriodicalIF":0.0,"publicationDate":"2025-03-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143721612","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Diagnostic utility of pleuroscopic guided pleural biopsy versus pleural fluid cell block in the diagnosis of malignant pleural effusion.","authors":"B H Ng, H J Low, N N N Abeed, C I Soo, M I Azmi, N S Sharil, R A Osman, M F A Hamid, A Y L Ban","doi":"","DOIUrl":"","url":null,"abstract":"<p><strong>Introduction: </strong>Pleural biopsy using flex-rigid pleuroscopy or pleural effusion cell block analysis is useful for diagnosing malignant pleural effusion. However, the current literature lacks documented comparisons between pleural biopsies and cytological cell blocks. This study aims to compare the diagnostic accuracy of pleural biopsy and cytological cell block in identifying malignant pleural effusion.</p><p><strong>Materials and methods: </strong>A retrospective review was conducted on patient data from those who underwent pleuroscopy at Hospital Canselor Tuanku Muhriz from January 2021 to December 2023. We included patients with pleural effusion who underwent both cell block and pleural biopsy with a confirmed diagnosis of malignancy through histopathological examination. At least 200 ml of pleural fluid was collected, followed by the biopsy of six or more pleural tissue samples.</p><p><strong>Results: </strong>Out of the 196 pleuroscopy procedures analysed, 91 patients were diagnosed with malignant pleural effusion. Malignancy was diagnosed in 50 (54.9%) cases using cell block analysis, whereas pleural biopsy identified malignancy in 81 (89%) cases. The diagnostic yield was significantly higher for pleural biopsy compared to pleural fluid cell block [89% (81/91) vs. 54.9% (50/91); p < 0.001]. Among patients with negative results on pleural fluid cell block, 33 (36.3%) had positive results on pleural biopsy. The definitive diagnoses of malignancy included 64 (70.3%) cases of lung adenocarcinoma, 4 (4.4%) cases of lung squamous carcinoma, 2 (2.2%) cases of small cell lung cancer, 2 (2.2%) cases of mesothelioma, and 19 (20.9%) cases of metastatic carcinoma. Eight (8.8%) patients exhibited negative findings on both pleural fluid cell block and pleural biopsy. Further diagnoses were achieved through computed tomography-guided needle tru-cut biopsy of the lung in 6 patients (6.6%), transbronchial lung biopsy in 1 patient (1.1%), and cervical lymph node biopsy in 1 patient (1.1%).</p><p><strong>Conclusion: </strong>Pleural biopsy exhibits superior diagnostic accuracy compared to pleural fluid cell block analysis for malignant pleural effusion. In cases where cell block results are negative but suspicion remains high, pleural biopsy remains a crucial diagnostic tool.</p>","PeriodicalId":39388,"journal":{"name":"Medical Journal of Malaysia","volume":"80 2","pages":"168-173"},"PeriodicalIF":0.0,"publicationDate":"2025-03-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143721823","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"An overview of hyperacute stroke services and National Stroke Registry in Malaysia - Improving stroke care through evidence.","authors":"C J Chin, S A Albart, A H K Yusof Khan, W A Wan Zaidi, N N Sidek, J P Schee, I Looi, F K Hoo","doi":"","DOIUrl":"","url":null,"abstract":"<p><strong>Introduction: </strong>Stroke is a leading cause of death and disability in Malaysia. This paper provides an overview of the stroke burden, hyperacute stroke services, importance, and challenges of stroke registries. It also details findings from the National Stroke Registry (NSR) Malaysia that have advanced knowledge on local patterns, inequalities and temporal trends in stroke presentation, care processes and outcomes.</p><p><strong>Materials and methods: </strong>A recent survey that involved all the government (Ministry of Health, MOH) and university hospitals in Malaysia was conducted by a group of neurologists and researchers to provide insights into the hyperacute stroke services in Malaysia from 2012 to 2023.</p><p><strong>Results: </strong>The results from the survey found that out of 142 MOH hospitals, 29 (20%) hospitals offer only intravenous thrombolysis (IVT) service, and seven (5%) hospitals offer both IVT and mechanical thrombectomy (MT) services. The majority or two-thirds of MOH hospitals still offer office hour services for both IVT and MT. For university hospitals, four (67%) out of six university hospitals provide both IVT and MT services and one (16%) university hospital provides only IVT service. Most university hospitals offer 24-hour services for IVT and MT. The availability of IVT service across MOH hospitals has increased significantly from 2012 to 2023. Thus, there was a substantial increase in the number of IVT cases treated in MOH hospitals. The growth in MT service has been more gradual. Only 22% of the MOH hospitals that provide hyperacute stroke services are equipped with acute stroke unit (ASU). Whereas ASU is available in 80% of the university hospitals that offer hyperacute stroke services. The higher availability of ASU in university hospitals compared to MOH hospitals may be due to better resources, specialised expertise, and advanced facilities in the university hospitals. The National Stroke Registry (NSR) Malaysia was established in 2009 to monitor stroke management practices, patient outcomes and promote quality improvement initiatives.</p><p><strong>Conclusion: </strong>Despite suboptimal adherence on several key performance indicators, the NSR reports recent improvements in thrombolysis rates, reduced mortality, and better functional outcomes. Key recommendations center on promoting greater participation, feedback systems, adequate funding, and governance structures to translate registry findings into national policies and targeted interventions for equitable access to quality stroke care.</p>","PeriodicalId":39388,"journal":{"name":"Medical Journal of Malaysia","volume":"80 2","pages":"266-274"},"PeriodicalIF":0.0,"publicationDate":"2025-03-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143721802","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"A 15-year experience with keratoplasty in the management of paediatric corneal diseases: indications and clinical outcomes in Malaysia.","authors":"Y Z Wai, R Alias, N A Bahari, T Umapathy, S I Hosnaliza, J Rahmat","doi":"","DOIUrl":"","url":null,"abstract":"<p><strong>Introduction: </strong>Corneal blindness is a leading yet preventable cause of childhood blindness worldwide. Despite the need for corneal transplantation in paediatric cases, comprehensive data on its aetiology, clinical outcomes, and graft survival in Malaysia remain scarce. This study reviews the indications and outcomes of paediatric keratoplasty at Hospital Kuala Lumpur over the past 15 years.</p><p><strong>Materials and methods: </strong>We conducted a retrospective evaluation of paediatric patients (less than 12-years-old) who underwent keratoplasty in Hospital Kuala Lumpur, from January 2008 to December 2022. We analysed demographic data, preoperative diagnoses, types of keratoplasty performed, and the 1-year graft survival rate.</p><p><strong>Results: </strong>100 eyes from 95 patients were included in the study, with a mean age of 4.39 ±3.32 years. The indications for keratoplasty included limbal dermoid (45%), anterior segment dysgenesis/Peter's anomaly (22%), infective keratitis (14%), congenital glaucoma (4%), and other pathologies (15%). 31/100 (31%) had corneal perforation. Of the patients, 56% underwent lamellar keratoplasty (LK), while 44% underwent penetrating keratoplasty (PK). Complications included wound dehiscence (4%) and graft melting (3%). 77% completed 1-year follow-up, and the overall 1-year graft survival rate was 54.5%. Limbal dermoid showed a better graft survival rate (72.2%) compared to other pathologies (39%), with a p-value of 0.004. LK has a higher 1-year graft survival rate of 66% compared to PK (36.7%) with a p-value of 0.003. Among the cases of perforated corneas, an overall 1-year graft survival rate of 25.8% (8/31) was observed, which was significantly lower compared to eyes without corneal perforation 73.9% (34/46) with a p-value of 0.008.</p><p><strong>Conclusions: </strong>Limbal dermoid was the most common indication for paediatric keratoplasty, and it exhibited a better graft survival rate compared to other pathologies. A one-year graft survival rate varies among different indications of keratoplasty. Perforated cornea has a lower graft survival rate compared to non-perforated corneal pathology.</p>","PeriodicalId":39388,"journal":{"name":"Medical Journal of Malaysia","volume":"80 2","pages":"141-146"},"PeriodicalIF":0.0,"publicationDate":"2025-03-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143721799","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Non-statin therapy in patients with elevated LDL-C and high platelet reactivity: a narrative review.","authors":"F N Nurmukhammad, B Zhangelova Sh, D A Кapsultanova, A T Musagaliyeva, L B Danyarova, F E Rustamova, A B Sugraliyev, G E Ospanova","doi":"","DOIUrl":"","url":null,"abstract":"<p><strong>Introduction: </strong>Evidence of an association between elevated LDL-C levels and HRPR - which are highly prevalent separately and both lead to rapid progression of atherosclerosis on ineffective hypolipidaemic therapy - is scarce.</p><p><strong>Materials and methods: </strong>We searched electronic databases. All available randomized controlled trials (RCTs) were included, and we considered the scientific novelty of the study, the reliability of the reported study results; the high methodological level of the study of non-statin therapy in patients with dyslipidemia and high residual platelet reactivity, with no language or date restrictions. We did separate random-effects meta-analyses for LDL-С, HRRP on their effects on LDL-С levels and outcomes, taking into account the reliability of the reported study results and the high methodological level of the study. The challenge of achieving target LDL-С levels, their impact on high residual platelet reactivity, and the choice of optimal antiplatelet and lipid-lowering therapy remains unresolved.</p><p><strong>Results: </strong>The integration of newer therapies, such as inclisiran and PCSK9 inhibitors, may play a critical role in achieving optimal outcomes for patients at high cardiovascular risk.</p><p><strong>Conclusion: </strong>The necessity of applying an individual multidisciplinary approach in order to determine the best regimen of antiplatelet and lipid-lowering therapy in patients with coronary heart disease, including after revascularization, is shown. This approach will reduce the risk of recurrent cardiovascular events. Few studies on the relationship between LDL-С and HRPR dictate the need for more detailed research in this area.</p>","PeriodicalId":39388,"journal":{"name":"Medical Journal of Malaysia","volume":"80 2","pages":"258-265"},"PeriodicalIF":0.0,"publicationDate":"2025-03-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143721871","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Cross-cultural adaptation and validation of the Malay Adult cirrhosiS Knowledge Questionnaire (ASK-QM).","authors":"H K Leung, S Mahadeva, R B Rajaram, H Omar, P S M Lai","doi":"","DOIUrl":"","url":null,"abstract":"<p><strong>Introduction: </strong>Cirrhosis is common in Malaysia, but no questionnaire in the local language (Malay) has been developed to assess patients' knowledge of this disease. This study aimed to adapt and validate the Malay Adult cirrhosiS Knowledge Questionnaire (ASK-QM).</p><p><strong>Materials and methods: </strong>ASK-QM was translated from English to Malay according to international guidelines. It was validated among cirrhotic patient who understand Malay language from two major liver centers in Klang Valley, Malaysia (University of Malaya and Hospital Selayang) from January 2021 to March 2022, at week 0 and 2. Patients with hepatic encephalopathy were excluded.</p><p><strong>Results: </strong>121 out of 132 patients with cirrhosis agreed to participate (response rate=91.7%). The overall median score of the ASK-QM was 54.5 [38.6-68.2] and the difficulty factor was 0.5 (range: 0.1-0.8 for each domain). Confirmatory factor analysis showed a good model fit with results of Comparative fit index (CFI) ranging from 0.836 to 1.000, whilst, the Tucker-Lewis index (TLI) ranged from 0.690 to 1.004 across all four domains. The root mean square error of approximation (RMSEA) value was reported from 0.000 to 0.100. For standardized root mean squared residual (SRMR) was from 0.008 to 0.015. Patients with tertiary education scored higher compared to those without (63.6 [45.5-77.3] vs 52.3 [36.4-63.6], p<0.05). The overall Kuder-Richardson (KR) coefficient was 0.761 indicating adequate internal consistency. Test-retest among 82 out of 121 patients (response rate=67.7%) demonstrated adequate reliability with eighteen out of 22 items having Wilcoxon signed-rank test values that were statistically not significant, p>0.005.</p><p><strong>Conclusion: </strong>The ASK-QM was found to be a valid and reliable questionnaire for evaluating knowledge of liver cirrhosis amongst Malay-speaking adults.</p>","PeriodicalId":39388,"journal":{"name":"Medical Journal of Malaysia","volume":"80 2","pages":"118-126"},"PeriodicalIF":0.0,"publicationDate":"2025-03-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143721818","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}