Medical Journal of Malaysia最新文献

{"title":"High concordance between Immunohistochemistry and RT-PCR in diagnosing ALK rearrangement in lung adenocarcinoma cytologic samples.","authors":"D S Heriyanto, L Rachmadi, I Trisnawati, J B Tenggara, R Cempaka, H Aribowo, Y Kurnia, V Lau, A N Gunawan, B N Halim, F S Yuliani, V Laiman, H C Chuang","doi":"","DOIUrl":"","url":null,"abstract":"<p><strong>Introduction: </strong>Lung cancer, predominantly lung adenocarcinoma, remains a major health challenge in Indonesia, with late-stage detection being common. This study explores the use of quantitative real-time polymerase chain reaction (qRT-PCR) for assessing ALK rearrangement from smear samples, a significant shift towards less invasive diagnostic methods, by assessing its concordance with immunohistochemistry (IHC) in detecting Anaplastic Lymphoma Kinase (ALK) rearrangements in lung adenocarcinoma patients.</p><p><strong>Materials and methods: </strong>This observational cross-sectional study analyzed 175 lung adenocarcinoma samples lacking EGFR mutations collected between 2018 and 2022. IHC was performed with the Ventana ALK D5F3 clone antibody on cell blocks or core needle biopsy specimens. The EML4-ALK fusion rearrangement status was determined using quantitative RNA qRT-PCR analysis on the smear specimen from transthoracic needle aspiration (TTNA) from the same sample. Only specimens with viable tumor cells were included, ensuring the exclusion of metastatic or necrotic samples.</p><p><strong>Results: </strong>ALK rearrangements were identified in 16.2% (23/142) of samples via IHC and 14.8% (21/142) via qRT-PCR. Prevalence did not significantly differ by age and sex. The study found a 98.5% concordance rate between the two methods, with a κ coefficient of 0.95 (95% CI, 0.91-0.98), indicating almost perfect agreement.</p><p><strong>Conclusion: </strong>The high concordance between IHC and qRTPCR underscores their reliability in detecting ALK rearrangements, crucial for the precise diagnosis and treatment of lung adenocarcinoma in Indonesia. These findings support the use of either method, depending on available resources and expertise, to enhance lung cancer management.</p>","PeriodicalId":39388,"journal":{"name":"Medical Journal of Malaysia","volume":"80 3","pages":"366-372"},"PeriodicalIF":0.0,"publicationDate":"2025-05-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144174047","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Mental state classification based on electroencephalogram (EEG) using multiclass support vector machine.","authors":"S W Purnami, S Karimah, S Andari, D P Wulandari, Y S Hadiwidodo, W R Islamiyah, M M Maramis, J M Zain","doi":"","DOIUrl":"","url":null,"abstract":"<p><strong>Introduction: </strong>Mental state refers to a person's state of mind from various perspectives, including consciousness, intention, and functionalism. Mental states closely related to everyday life include the concentrating state, neutral state, and relaxation state. Concentration is vital for cognitive tasks, while relaxation is crucial for comfort. However, individuals with mental disorders or neurological conditions often struggle to achieve these states, requiring effective detection and intervention. One method for detecting mental states is by using brainwave signals obtained through electroencephalogram (EEG). EEG has been widely used in neuroscience and clinical settings to objectively assess mental states by analyzing brainwave signals. Previous studies have demonstrated the potential of EEG-based mental state classification in stress detection, cognitive workload analysis, or depression detection.</p><p><strong>Materials and methods: </strong>The data used in this research is secondary data in the form of recorded brainwave signals using EEG from 2018. and utilises self-reported data obtained from locally validated personal stress inventory questionnaires. The data used was obtained from four participants, including two females and two males. For preprocessing, this study uses the Hamming Windows Finite Impulse Response filtering method to extract features from each wave band. Additionally, feature selection methods are applied to choose the most relevant predictor features. Multiclass Support Vector Machine (SVM) with One-Against- One (OAO) and One-Against-All (OAA) approaches are used for classification.</p><p><strong>Results: </strong>The feature selection process reduced the number of predictor variables from 160 to 40, focusing on minimum and maximum feature values. Multiclass SVM classification using 40 predictor variables achieved an AUC range of 0.907-0.922 (OAA) and 0.854-0.927 (OAO), while classification using all predictor variables yielded an AUC range of 0.898-0.927 (OAA) and 0.917-0.941 (OAO). Comparative performance analysis indicates that the OAA approach is superior to the OAO approach.</p><p><strong>Conclusion: </strong>This study highlights the effectiveness of EEGbased classification of mental states using the Multiclass SVM method. The findings reinforce the role of EEG as an objective tool for mental state assessment, supporting its potential application in clinical and cognitive research for early detection of mental health disorders.</p>","PeriodicalId":39388,"journal":{"name":"Medical Journal of Malaysia","volume":"80 3","pages":"352-358"},"PeriodicalIF":0.0,"publicationDate":"2025-05-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144174517","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Mild cognitive impairment and its associated factors amongst the older people attending government health clinics in Kuantan.","authors":"Y Atri Roop, M S E Shalihin, E Mohammad Aidid","doi":"","DOIUrl":"","url":null,"abstract":"<p><strong>Introduction: </strong>Malaysia is undergoing a demographic transition towards an aging population, resulting in an anticipated rise in the number of older individuals at risk of developing dementia. Mild cognitive impairment (MCI) represents an intermediate clinical stage between normal cognition and dementia, characterized by cognitive decline that does not significantly impair daily functional activities. Early detection of MCI is critical, as early-stage interventions and modifications of risk factors can yield promising outcomes.</p><p><strong>Materials and methods: </strong>This cross-sectional study evaluated the prevalence of MCI and its associated factors among 327 older adults attending healthcare clinics. Data were collected using the Elderly Cognitive Assessment Questionnaire, Geriatric Depression Scale, and Barthel Index. Binary logistic regression analysis was performed to identify significant factors of MCI.</p><p><strong>Results: </strong>The prevalence of MCI in the study population was 18.7%, with the majority demonstrating poor control of comorbid conditions. Significant factors of MCI included being a widower (OR 0.4; 95%CI: 0.18, 0.94), increasing age (OR 0.92; 95% CI: 0.88, 0.97), and having diabetes (OR 3.49; 95% CI: 1.81, 6.73).</p><p><strong>Conclusion: </strong>The findings highlight that a significant proportion of older adults are at risk of progressing to dementia but remain underdiagnosed during the early stages. Optimizing blood sugar control emerges as a crucial strategy to mitigate the progression of MCI to irreversible dementia. Implementation of active cognitive screening programs is essential for early identification and timely intervention.</p>","PeriodicalId":39388,"journal":{"name":"Medical Journal of Malaysia","volume":"80 3","pages":"321-327"},"PeriodicalIF":0.0,"publicationDate":"2025-05-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144174903","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Mortality and risk factors in post-operative pancreatic fistula following pancreatoduodenectomy: A single centre experience.","authors":"G H Ong, V M Leow, S Manisekar","doi":"","DOIUrl":"","url":null,"abstract":"<p><p>No abstract available.</p>","PeriodicalId":39388,"journal":{"name":"Medical Journal of Malaysia","volume":"80 3","pages":"282-289"},"PeriodicalIF":0.0,"publicationDate":"2025-05-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144175076","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Credentialing & privileging an important factor for diagnostic accuracy of diabetic retinopathy screening in the health clinics of Penang.","authors":"A K Nasim, J Ahmad Taufik, I Khalid, T Rohana, E L Ang, A Farzaana","doi":"","DOIUrl":"","url":null,"abstract":"<p><strong>Introduction: </strong>Early detection and management of diabetic retinopathy (DR) is crucial in preventing blindness. Screening is recommended at diagnosis and yearly for Type 2 diabetes patients. DR screening using non-mydriatic fundus cameras (NMFC) has been extended to Health Clinics since 1997, but competency and experience of the medical officers (MOs) remain an issue in Primary Care. This study aims to assess the accuracy of the eye examination using NMFC for DR screening done by MOs and identify the factors associated with the accuracy.</p><p><strong>Materials and methods: </strong>This is a cross-sectional study using secondary data obtained from the Penang State Health Department, which conducted clinical audits of fundus images from health clinics in 2019. The audit involved two consultant ophthalmologists to comment on the accuracy of the interpretation of retinal images and the quality of the images sampled from all health clinics with NFMC. Sampling was performed on the audited data set to include diagnosis by the MOs and diabetic retinopathy spectrum of disease. The subject of the study was the images with the corresponding reports. The outcome of this study was the accurate interpretation of the images, as commented by the ophthalmologists. The independent variables studied were the demographic of the MOs who interpreted the images, their training background and the quality of the images.</p><p><strong>Results: </strong>The Universal sampling method was used, and the final 1129 images fulfilled the eligible criteria. The sensitivity, specificity, PPV and NPV were found to be 80.6%, 92.7%, 76.4% and 94.2%, respectively. Overall accuracy was 83.8%. After missing values were managed, 997 samples were analysed using logistic regression. The final model shows that significant factors associated with accuracy are foreign graduates MOs (Adjusted OR 1.98, 95% CI: 1.35-3.07), MOs with Credentialing & Privileging (Adjusted OR 2.32, 95% CI:1.32-2.88) and Good Image Quality (Adjusted OR 3.62,95% CI:2.37-5.71).</p><p><strong>Conclusion: </strong>MO with C&P showed better accuracy than MO without C&P. This study suggests that MOH should emphasise the C&P when performing this procedure in health clinics. As image quality showed the highest association with accuracy, strengthening the C&P among the paramedics who perform the procedure using NMFC to get the retinal images is also necessary. This study also indicates that evaluating DR screening programs in health clinics is necessary nationwide.</p>","PeriodicalId":39388,"journal":{"name":"Medical Journal of Malaysia","volume":"80 3","pages":"346-351"},"PeriodicalIF":0.0,"publicationDate":"2025-05-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144175225","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Training and testing of integrated professional skills in management of shoulder dystocia among Malaysian Health Care Providers.","authors":"J Thaneemalai, G Muniswaran, T Boon Nee, P T Gunasegaran","doi":"","DOIUrl":"","url":null,"abstract":"<p><strong>Introduction: </strong>To evaluate if the Intensive Course in Obstetric Emergencies (ICOE) Shoulder dystocia simulation training module could improve psychomotor and cognitive skills in the management of shoulder dystocia using a Test of Integrated Professional Skills (TIPS).</p><p><strong>Materials and method: </strong>This was a prospective observational study involving Malaysian health care professionals participating in ICOE shoulder dystocia simulation, where standardized curriculum was used. Pre and post-test skills assessment were conducted to evaluate the effectiveness of the course content and delivery.</p><p><strong>Results: </strong>609 Malaysian health care professionals attended ICOE training; 400 midwives, 128 medical officers, 55 specialist and 26 consultants. Participants were derived from 25 consecutive courses, from 2014 to 2019 and tested on predetermined skills in the management of shoulder dystocia. Their mean TIPS pre-test vs post-test score were (2.55 vs 6.77) midwives, (3.78 vs 7.25) medical officers, (5.16 vs 7.82) specialists & (3.62 vs 6.88) consultants. All four group of participants showed statistically significant improvement (51-165%) in their skills (p<0.001). The mean post test score in noting time of dystocia and call for help were significantly higher among midwives than others. All four groups statistically improved their delivery skills in McRoberts manoeuvre and directed suprapubic pressure. Pre-skills for delivery of the posterior arm was suboptimal and post skills test showed statistically significant improvement in all four groups.</p><p><strong>Conclusion: </strong>ICOE shoulder dystocia simulation training module improved the psychomotor and cognitive skills in the management of delivery of shoulder dystocia.</p>","PeriodicalId":39388,"journal":{"name":"Medical Journal of Malaysia","volume":"80 2","pages":"206-211"},"PeriodicalIF":0.0,"publicationDate":"2025-03-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143721382","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Complementary feeding based on local-food to improve mother ability in fulfillment nutrition stunted children.","authors":"P H Apriyani, W K Ardhiles, R Fani, D Soares, W Shinta, M Hanim, G A Rakhmadani, Indari","doi":"","DOIUrl":"","url":null,"abstract":"<p><strong>Introduction: </strong>Mothers have the ability to provide adequate nutrition for their children. The role of providing nutrition to children aged 6-24 months who are stunted correlated to the mother's ability to provide proper nutrition. The role of mother can be carried out using the ability, confidence, and self-capacity to complete tasks, managing and providing nutrition to children aged 6-24 months who are stunted. This study aimed to analyze complementary feeding based on local food to improve the mothers' ability to fulfill their needs in stunted children.</p><p><strong>Materials and methods: </strong>A pre-experiment design was used to obtain data regarding 180 mothers who participated in this study. The complementary feeding based on local- food was conducted for 9 weeks, comprising 2 weeks preintervention, 6 weeks of intervention, and one-week postintervention. The intervention consists of 12 sets of recipes to be made by mothers and given to their children 4 times daily over 6 weeksinstrument using Infant and Young Children Feeding Practice and Structure questionnaire. Data analysis in this study used Wilcoxon Signed Rank Test.</p><p><strong>Results: </strong>The result of this study showed that complementary feeding based on local- food could give the impact mothers ability in food preparation and processing before complementary feeding (Z=11.644 and pvalue= 0.000), supplemental feeding (Z=-11.641 and p-value 0.000), and responsive feeding (Z-11.640 and p-value 0.000). The role of feeding responsiveness in accelerated growth. These results prove that self-feeding and maternal verbal responsiveness can be increased by targeting specific behaviours with appropriate behaviour change modeling and coaching practice strategies.</p><p><strong>Conclusion: </strong>These results provide evidence that focusing on specific behaviours and implementing modification techniques such as modeling and coached practice, complementary feeding based on local food, self-feeding, and maternal verbal responsiveness can be improved.</p>","PeriodicalId":39388,"journal":{"name":"Medical Journal of Malaysia","volume":"80 2","pages":"127-132"},"PeriodicalIF":0.0,"publicationDate":"2025-03-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143721815","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Free omental patch as the promising future for incisional hernia surgery: an experimental study in rat model.","authors":"I Sofii, I Widodo, Gunadi, A Y Handaya","doi":"","DOIUrl":"","url":null,"abstract":"<p><strong>Introduction: </strong>Incisional hernia is the common complication of abdominal surgery with serious morbidity. The use of Composite mesh (CM) is the current gold standard, which is superior to Polypropylene mesh (PPM) for closing the defect, due to its minimal intraabdominal adhesion. In this study, we were using the novel combination of free omental patch (FOP) and PPM compared to CM for defect closure surgery in incisional hernia using rat models. We compared the gene expression of VEGF, COL3A1, COL1A1, COL1A2, and ratio of COL1A1/COL3A1 as the representative of wound healing process from all treatment options.</p><p><strong>Materials and methods: </strong>Eighteen wistar rats were made into incisional hernia models and divided into three groups of FOP, FOP-PPM, and CM at the 14th day. After each group underwent hernia repair, abdominal wall samples were taken to examine the expression of qPCR VEGF, COL3A1, COL1A1, and COL1A2 at the 21st day.</p><p><strong>Results: </strong>There were no significant different in the gene expression of VEGF, COL3A1, COL1A1, COL1A2 and COL1A1/COL3A1 ratio between FOP, FOP-PPM and CM group (p-value >0.05). In addition, non-significant result also found at the comparative analysis between FOP-PPM and MC groups.</p><p><strong>Conclusions: </strong>FOP can give the similar result as CM for defect closure surgery in incisional hernia, either when combined with PPM or as a single option. However, further clinical study is needed to support this animal study.</p>","PeriodicalId":39388,"journal":{"name":"Medical Journal of Malaysia","volume":"80 2","pages":"174-177"},"PeriodicalIF":0.0,"publicationDate":"2025-03-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143721848","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"The survival outcomes of unilateral retinoblastoma in Malaysia.","authors":"A S Ain-Nasyrah, J Rahmat, S A Ghani, I Shatriah","doi":"","DOIUrl":"","url":null,"abstract":"<p><p>Retinoblastoma (RB) is the most common malignant intraocular tumour in children and can present as unilateral or bilateral disease. Unilateral RB represents 60% of all cases and tend to present at a relatively advanced stage of RB. Unilateral RB in Malaysia has a one-year survival rate of 99.0% and five-year survival of 93.0%. Shorter lag time, longer duration of follow-up and compliance with follow-up are good prognostic factors for the survival of unilateral RB patients. It is essential to report the prognostic factors associated with unilateral RB in our population. This information will assist healthcare professionals in understanding the factors that influence outcomes and support the development of long-term treatment guideline.</p>","PeriodicalId":39388,"journal":{"name":"Medical Journal of Malaysia","volume":"80 2","pages":"113-117"},"PeriodicalIF":0.0,"publicationDate":"2025-03-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143721431","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Impact of computerized provider order entry system on medication prescribing errors in hospital wards: a comparative study.","authors":"C Y Saw, A K Nadzirah, N S Nagappan, W Joan, M T Lim","doi":"","DOIUrl":"","url":null,"abstract":"&lt;p&gt;&lt;strong&gt;Introduction: &lt;/strong&gt;Medication errors are a major concern in healthcare, threatening patient safety and increasing costs. These errors can occur at various stages, from prescribing to dispensing and administration. Among these, prescribing errors are particularly critical as they occur at the initial step of medication use process and can propagate downstream, potentially leading to adverse events. Computerized provider order entry (CPOE) systems, with integrated clinical decision support tools offer significant benefits over handwritten prescriptions including enhanced legibility, prescription completeness, standardization, a comprehensive audit trail and real-time alerts and reminders to assist prescribers during the prescribing process. This study aims to evaluate the effectiveness of a CPOE system with clinical decision support features in reducing prescribing errors across the hospital. It compares the rates and error types between electronic and handwritten prescriptions over different time periods following the CPOE implementation.&lt;/p&gt;&lt;p&gt;&lt;strong&gt;Materials and methods: &lt;/strong&gt;This retrospective comparative analysis examines inpatient prescription data collected from the same hospital wards during three distinct periods: 1st January to 31st March 2023 (59,663 handwritten prescriptions), 1st October to 31st December 2023 (43,363 electronic prescriptions at 3 months post-CPOE implementation) and 1st January to 31st March 2024 (44,317 electronic prescriptions at 6 months post-CPOE implementation). The CPOE system was implemented in July 2023.&lt;/p&gt;&lt;p&gt;&lt;strong&gt;Results: &lt;/strong&gt;The CPOE system significantly reduced medication prescribing errors (3 months post-CPOE: n=832, 1.92%; 6 months post-CPOE: n=617, 1.39%) compared to handwritten prescriptions (n=3532, 5.92%). The odds of errors occurring 3 months and 6 months post-CPOE implementation were 65% and 75% lower, respectively, than during the handwritten phase [Odds Ratio (OR), 0.35; 95% Confidence Interval (CI), 0.32 - 0.38] and [OR, 0.25; 95% CI, 0.23 - 0.28]. Potential error sources associated with handwritten prescriptions, such as illegible prescriptions, non-standard abbreviations and incomplete prescriptions, were entirely eliminated with CPOE adoption. Significant differences in error types were observed between handwritten and electronic prescriptions (p&lt;0.001). However, errors related to incorrect dosage, frequency and unit of measurement increased under the CPOE system compared to handwritten prescriptions (p&lt;0.001). A significant reduction in odds occurred with wrong unit of measurement [OR, 0.61; 95% CI, 0.52 - 0.72) followed by frequency errors [OR, 0.58; 95% CI, 0.47 - 0.73) from the 3 months to 6 months post-CPOE implementation. Non-significant reductions or increments in odds were observed for other error types including wrong dosage, wrong route, wrong form, wrong strength and wrong or inappropriate drugs between the two 3-month post-CPOE periods.&lt;/p&gt;&lt;p&gt;&lt;strong&gt;Co","PeriodicalId":39388,"journal":{"name":"Medical Journal of Malaysia","volume":"80 2","pages":"228-234"},"PeriodicalIF":0.0,"publicationDate":"2025-03-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143721811","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}