{"title":"Changes in fundus by optical coherence tomography in patients with chronic obstructive pulmonary disease: A systematic review.","authors":"A Kim, C Erb, G Kapanova","doi":"","DOIUrl":null,"url":null,"abstract":"<p><strong>Introduction: </strong>Chronic obstructive pulmonary disease (COPD) exerts a negative impact on various tissues and organs throughout the body due to chronic hypoxia. The retina and choroid are implicated in this process, and the application of optical coherence tomography (OCT) enables the detection of potential changes in the fundus. This study aims to explore and discuss OCT-assisted fundus alterations in individuals with COPD by undertaking a systematic review.</p><p><strong>Materials and methods: </strong>A systematic review of the literature was conducted in adherence to the PRISMA checklist. Exclusion criteria encompassed articles published in non- peer-reviewed journals or unpublished literature. Consistent criteria were applied during both the title-and-abstract screening and full-text screening phases. Inclusion criteria comprised research conducted in the English language and published after 1993. Selection criteria were articulated in accordance with PICOS. Articles falling within the purview of meta-analyses, systematic reviews, guidelines, case reports, pilot studies, and non-human studies (e.g., laboratory research) were excluded from consideration.</p><p><strong>Results: </strong>A total of 68 articles were initially identified, 10 reports met inclusion criteria and were included in qualitative analysis. In Turkey were conducted 8 studies and 2 studies in Egypt. All the studies included are case-control designed. Above-mentioned changes in retina were studied in 10 cases and found in 8 of them. In the same time changes in choroid were studied in 9 cases and found in 6 of them.</p><p><strong>Conclusions: </strong>The findings of this systematic review indicate that, as observed through OCT, chronic hypoxia and systemic inflammation resulting from COPD predominantly impact the retina and choroid.</p>","PeriodicalId":39388,"journal":{"name":"Medical Journal of Malaysia","volume":"80 5","pages":"635-641"},"PeriodicalIF":0.0000,"publicationDate":"2025-09-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":"0","resultStr":null,"platform":"Semanticscholar","paperid":null,"PeriodicalName":"Medical Journal of Malaysia","FirstCategoryId":"1085","ListUrlMain":"","RegionNum":0,"RegionCategory":null,"ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"","PubModel":"","JCR":"Q3","JCRName":"Medicine","Score":null,"Total":0}
引用次数: 0
Abstract
Introduction: Chronic obstructive pulmonary disease (COPD) exerts a negative impact on various tissues and organs throughout the body due to chronic hypoxia. The retina and choroid are implicated in this process, and the application of optical coherence tomography (OCT) enables the detection of potential changes in the fundus. This study aims to explore and discuss OCT-assisted fundus alterations in individuals with COPD by undertaking a systematic review.
Materials and methods: A systematic review of the literature was conducted in adherence to the PRISMA checklist. Exclusion criteria encompassed articles published in non- peer-reviewed journals or unpublished literature. Consistent criteria were applied during both the title-and-abstract screening and full-text screening phases. Inclusion criteria comprised research conducted in the English language and published after 1993. Selection criteria were articulated in accordance with PICOS. Articles falling within the purview of meta-analyses, systematic reviews, guidelines, case reports, pilot studies, and non-human studies (e.g., laboratory research) were excluded from consideration.
Results: A total of 68 articles were initially identified, 10 reports met inclusion criteria and were included in qualitative analysis. In Turkey were conducted 8 studies and 2 studies in Egypt. All the studies included are case-control designed. Above-mentioned changes in retina were studied in 10 cases and found in 8 of them. In the same time changes in choroid were studied in 9 cases and found in 6 of them.
Conclusions: The findings of this systematic review indicate that, as observed through OCT, chronic hypoxia and systemic inflammation resulting from COPD predominantly impact the retina and choroid.
期刊介绍:
Published since 1890 this journal originated as the Journal of the Straits Medical Association. With the formation of the Malaysian Medical Association (MMA), the Journal became the official organ, supervised by an editorial board. Some of the early Hon. Editors were Mr. H.M. McGladdery (1960 - 1964), Dr. A.A. Sandosham (1965 - 1977), Prof. Paul C.Y. Chen (1977 - 1987). It is a scientific journal, published quarterly and can be found in medical libraries in many parts of the world. The Journal also enjoys the status of being listed in the Index Medicus, the internationally accepted reference index of medical journals. The editorial columns often reflect the Association''s views and attitudes towards medical problems in the country. The MJM aims to be a peer reviewed scientific journal of the highest quality. We want to ensure that whatever data is published is true and any opinion expressed important to medical science. We believe being Malaysian is our unique niche; our priority will be for scientific knowledge about diseases found in Malaysia and for the practice of medicine in Malaysia. The MJM will archive knowledge about the changing pattern of human diseases and our endeavours to overcome them. It will also document how medicine develops as a profession in the nation. We will communicate and co-operate with other scientific journals in Malaysia. We seek articles that are of educational value to doctors. We will consider all unsolicited articles submitted to the journal and will commission distinguished Malaysians to write relevant review articles. We want to help doctors make better decisions and be good at judging the value of scientific data. We want to help doctors write better, to be articulate and precise.