Indian Journal of Tuberculosis最新文献_第3页

Catastrophic cost and coping strategies of tuberculosis patients in a block of Purba Bardhaman District, West Bengal: A crossectional study 西孟加拉邦Purba Bardhaman区一个街区结核病患者的灾难性成本和应对策略：一项横断面研究

Indian Journal of Tuberculosis Pub Date : 2025-07-01 DOI: 10.1016/j.ijtb.2024.08.012

Akash Dutta, Sutapa Mandal, Pranita Taraphdar, Sulagna Das

{"title":"Catastrophic cost and coping strategies of tuberculosis patients in a block of Purba Bardhaman District, West Bengal: A crossectional study","authors":"Akash Dutta, Sutapa Mandal, Pranita Taraphdar, Sulagna Das","doi":"10.1016/j.ijtb.2024.08.012","DOIUrl":"10.1016/j.ijtb.2024.08.012","url":null,"abstract":"<div><h3>Background</h3><div>The elevated expenses associated with tuberculosis (TB), can hinder access to treatment and adherence.</div></div><div><h3>Objectives</h3><div>This study was done to find out catastrophic cost (defined as 20% of the total annual income) resulting from treatment and diagnosis of TB, factors associated with it and delineated the coping mechanisms employed by the affected individuals and their families.</div></div><div><h3>Materials and methods</h3><div>A cross sectional study was conducted for a period of 6 months, September 2023 to February 2024, among 146 patients registered in the Tuberculosis Unit (TU) of Bhatar block, Purba Bardhaman District,West Bengal. A pre validated questionnaire was used for interviewing the patients. Data was analysed using the principles of descriptive statistics, organised and presented in the form of tables.</div></div><div><h3>Results</h3><div>Out of 146 tuberculosis (TB) patients, the study revealed mean total cost incurred for TB-related services amounted to Rs 30,046 ± Rs 9406 with direct cost of Rs 2964.26 ± Rs 990.3 and indirect cost of Rs 27,406 ± Rs 9,351.54(36.9%) of the study population reported that their families faced catastrophic costs. Coping strategies like taking loan emerged as the most prevalent means, with 45(30.8%) patients reporting it followed by selling livestock which was prevalent among 14(9.6%) of them.</div></div><div><h3>Conclusions</h3><div>In spite of the implementation of Universal Health Coverage, TB-affected households still faces the risk of catastrophic total costs. A cost-mitigation policy and financial protection should be provided additionally along with better health care facility to all patients.</div></div>","PeriodicalId":39346,"journal":{"name":"Indian Journal of Tuberculosis","volume":"72 3","pages":"Pages 354-357"},"PeriodicalIF":0.0,"publicationDate":"2025-07-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144686757","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Anti-TB treatment non-adherence predictors: A multi-center cross-sectional study in Kandahar, Afghanistan 不坚持抗结核治疗的预测因素：阿富汗坎大哈多中心横断面研究

Indian Journal of Tuberculosis Pub Date : 2025-07-01 DOI: 10.1016/j.ijtb.2024.05.005

Muhammad Haroon Stanikzai , Mohammad Hashim Wafa , Ahmad Haroon Baray , Ahmad Farshad Rahimi , Hadia Sayam

{"title":"Anti-TB treatment non-adherence predictors: A multi-center cross-sectional study in Kandahar, Afghanistan","authors":"Muhammad Haroon Stanikzai , Mohammad Hashim Wafa , Ahmad Haroon Baray , Ahmad Farshad Rahimi , Hadia Sayam","doi":"10.1016/j.ijtb.2024.05.005","DOIUrl":"10.1016/j.ijtb.2024.05.005","url":null,"abstract":"<div><h3>Background</h3><div>Adherence to anti-TB treatment in low- and middle-income countries (LMICs), including Afghanistan, is critical for global TB control.</div></div><div><h3>Objectives</h3><div>We aimed to determine anti-TB treatment non-adherence prevalence and its predictors in Kandahar, Afghanistan.</div></div><div><h3>Methods</h3><div>We conducted a multi-center cross-sectional study of 579 TB patients in Kandahar, using a systematic random sampling method, and collected their data on sociodemographic attributes, clinical factors, and mental health. The eight-item Tuberculosis Medication Adherence Questionnaire (TBMAQ) was used for labeling TB patients as adherent or non-adherent. We assigned a score of ≤4 (the cut-off) as non-adherence. We performed the multivariable logistic regression to probe significant predictors of non-adherence.</div></div><div><h3>Results</h3><div>The non-adherence rate in this study was 66.8% (95% CI: 62.9–70.5). Being uneducated (AOR = 1.66, 95 % CI: 1.09–2.53), having a comorbid medical condition (AOR = 2.57, 95 % CI: 1.39–4.74), feeling stigmatized for having TB (AOR = 9.25, 95 % CI: 4.72–18.1), and having a comorbid depression (AOR = 1.77, 95 % CI: 1.16–2.71) were associated with non-adherence.</div></div><div><h3>Conclusion</h3><div>Anti-TB treatment adherence needs to be prioritized among TB patients overall, particularly in those with a low level of education, comorbidity, perceived TB-related stigma, and comorbid depression with consistent evidence of increased non-adherence.</div></div>","PeriodicalId":39346,"journal":{"name":"Indian Journal of Tuberculosis","volume":"72 3","pages":"Pages 298-303"},"PeriodicalIF":0.0,"publicationDate":"2025-07-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141028600","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Thoracoscopic decortication for tubercular empyema in a lung transplant recipient 胸腔镜下肺移植术后结核性脓肿的脱屑治疗

Indian Journal of Tuberculosis Pub Date : 2025-07-01 DOI: 10.1016/j.ijtb.2024.08.017

Mohan Venkatesh Pulle , Anmol Bhan , Sukhram Bishnoi , Vivek Singh , Belal Bin Asaf , Harsh Vardhan Puri , Sumit Bangeria , Manan Bharatkumar Parikh , Anjali Singh , Arvind Kumar

引用次数: 0

Screening hemodialysis patients for tuberculosis in Sudan 苏丹血液透析患者肺结核筛查

Indian Journal of Tuberculosis Pub Date : 2025-07-01 DOI: 10.1016/j.ijtb.2024.08.013

Sarra Elamin , Selma S. Ibrahim, Hytham AD El-Mahdi, Amel Kailani, Shaza AM Mohamednour, Salma NA Mohamed, Tagwa MA Osman, Mohamed AA Abdulla, Sofyan MM Babiker, Hassan MAH Abubaker, May AO Suleiman

{"title":"Screening hemodialysis patients for tuberculosis in Sudan","authors":"Sarra Elamin , Selma S. Ibrahim, Hytham AD El-Mahdi, Amel Kailani, Shaza AM Mohamednour, Salma NA Mohamed, Tagwa MA Osman, Mohamed AA Abdulla, Sofyan MM Babiker, Hassan MAH Abubaker, May AO Suleiman","doi":"10.1016/j.ijtb.2024.08.013","DOIUrl":"10.1016/j.ijtb.2024.08.013","url":null,"abstract":"<div><h3>Objectives</h3><div>To estimate the prevalence of latent tuberculosis infection (LTBI) and the need for TB preventive treatment (TPT) among hemodialysis (HD) patients in Sudan.</div></div><div><h3>Methods</h3><div>We screened patients in a single HD center by two-step tuberculin skin test (TST), symptom survey, physical examination and chest radiography (CXR).</div></div><div><h3>Results</h3><div>The survey included 204 patients, five of whom (2.5%) had history of previously treated TB. The proportion of TST positive patients was 12.3% after the first test and increased to 21.1% after the second test. Patients previously treated for TB were more likely to have positive TST (80 vs 20.1%, p = 0.01). We screened 184 patients for TB disease; 16.3% were symptomatic, 15.8% had CXR abnormality and 6.5% were symptomatic with CXR abnormality. Additionally, 13.6% of patients had physical signs consistent with extra-pulmonary TB without symptoms or CXR abnormality. Based on these findings, high probability of pulmonary and extra-pulmonary TB was found in 38.6% and 13.6% of patients respectively and they were referred for bacteriological confirmation. We diagnosed LTBI and prescribed TPT to 9.2% of screened patients.</div></div><div><h3>Conclusion</h3><div>In this cohort of Sudanese HD patients, 21.1% were positive after two-step TST and 52.2% were considered to have high probability of TB disease.</div></div>","PeriodicalId":39346,"journal":{"name":"Indian Journal of Tuberculosis","volume":"72 3","pages":"Pages 358-361"},"PeriodicalIF":0.0,"publicationDate":"2025-07-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144686758","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Drug resistant tuberculous meningitis: A neglected foe in ending tuberculosis epidemic 耐药结核性脑膜炎：终结结核病流行的一个被忽视的敌人

Indian Journal of Tuberculosis Pub Date : 2025-07-01 DOI: 10.1016/j.ijtb.2024.09.004

Leeberk Raja Inbaraj , Bella Devaleenal Daniel , Chandrasekaran Padmapriyadarsini

引用次数: 0

“The validation of a multidimensional tool to test knowledge, barriers, and the challenges in screening for Tuberculosis among patients with Diabetes Mellitus” "测试糖尿病患者肺结核筛查知识、障碍和挑战的多维工具的验证

Indian Journal of Tuberculosis Pub Date : 2025-07-01 DOI: 10.1016/j.ijtb.2024.04.007

Monisha Mary P , Ankeeta Menona Jacob , Avinash Shetty

{"title":"“The validation of a multidimensional tool to test knowledge, barriers, and the challenges in screening for Tuberculosis among patients with Diabetes Mellitus”","authors":"Monisha Mary P , Ankeeta Menona Jacob , Avinash Shetty","doi":"10.1016/j.ijtb.2024.04.007","DOIUrl":"10.1016/j.ijtb.2024.04.007","url":null,"abstract":"<div><h3>Background</h3><div>The National Coordination Committee (NCC) for the National Tuberculosis Elimination Programme (NTEP) has mandated bi-directional screening for Tuberculosis(TB) and Diabetes Mellitus(DM). The study aims to validate a multidimensional tool to assess the correct knowledge of TB and the barriers and facilitators to TB screening in DM patients.</div></div><div><h3>Aim/objectives</h3><div>To develop and validate a tool for assessing knowledge, barriers, and challenges in TB screening among DM patients by figuring out the Content Validity Ratios and Indices.</div></div><div><h3>Methods and materials</h3><div>A multidimensional scale using deductive methods was designed. Between January 2023 and March 2023, ten subject matter experts were contacted in person or by email to validate the tool. Item Impact Score (IIS, Face Validity), Lawshe's Content Validity Ratio (CVR), and Scale Content Validity Indices (CVI) for relevance were computed. For the final tool, only the items with Item Impact Scores of ≥1.5, CVRs of ≥0.62, and CVIs of ≥0.62 (p-value <0.05) were taken into consideration.</div></div><div><h3>Results</h3><div>The Item Impact Score (Face Validity) of all the items accepted as knowledge, barriers, and challenges for TB among DM patients was ≥1.5. Content Validity Ratios (CVR) for the usefulness of all items related to knowledge, barriers, and challenges for TB was ≥0.62. The Scale Content Validity Indices (for relevance), i.e., S-CVI (Average) and S-CVI (Proportional relevance), were ≥0.62 and all the items were accepted.</div></div><div><h3>Conclusions</h3><div>The score for Item Impact (IIS), Ratios for Content Validity (CVR), and Indices measuring the content validity of a scale (CVI) in all domains of the final tool were accepted, which contained 38 items.</div></div>","PeriodicalId":39346,"journal":{"name":"Indian Journal of Tuberculosis","volume":"72 3","pages":"Pages 283-289"},"PeriodicalIF":0.0,"publicationDate":"2025-07-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"140784592","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Rare presentation of pulmonary tuberculosis as diffuse alveolar hemorrhage 肺结核罕见表现为弥漫性肺泡出血

Indian Journal of Tuberculosis Pub Date : 2025-07-01 DOI: 10.1016/j.ijtb.2024.11.001

Srikant K. Malegaonkar

引用次数: 0

Healthcare schemes to overcome financial toxicity of COVID-19: A retrospective single center study 克服 COVID-19 经济毒性的医疗保健方案：单中心回顾性研究

Indian Journal of Tuberculosis Pub Date : 2025-07-01 DOI: 10.1016/j.ijtb.2024.04.010

Anjana Madhusoodanan , Raushan Kumar Chaudhary , Shivakumar Hiremath , Uday Venkat Mateti , Shraddha Shetty

{"title":"Healthcare schemes to overcome financial toxicity of COVID-19: A retrospective single center study","authors":"Anjana Madhusoodanan , Raushan Kumar Chaudhary , Shivakumar Hiremath , Uday Venkat Mateti , Shraddha Shetty","doi":"10.1016/j.ijtb.2024.04.010","DOIUrl":"10.1016/j.ijtb.2024.04.010","url":null,"abstract":"<div><h3>Background</h3><div>Indian healthcare system nearly crashed during the pandemic and victims of COVID-19 experienced huge health related economic burden. Thus, we aimed to quantify the direct medical cost associated with COVID-19 management along with the healthcare schemes.</div></div><div><h3>Methods</h3><div>A retrospective study was conducted for the duration of 8 months where the data of COVID-19 patients of one year (2020–2021) was collected from the medical record department. The data of COVID-19 patients of age 18–65 years with confirmed diagnosis based on RT-PCR test were included in the study whereas the data of special population such as pregnant, hemodialysis and patient undergoing surgery were excluded.</div></div><div><h3>Results</h3><div>Out of 1011 COVID-19 patients, 63.5% were males and 36.5% were female with the mean age of 43.8 ± 14.5 years and with 9.47 days mean length of hospitalization. On direct medical cost analysis, USD 1060.92 was the total median expenses which includes COVID package plus outside COVID package expenses. Similarly, USD 728 and USD 51.1 were the median amount claimed through healthcare schemes and median co-payments respectively. The total median expenses with and without healthcare schemes were found to be USD 1061.37 and USD 1052.94 respectively whereas co-payments with and without schemes were USD 26.005 and USD 1046.64.</div></div><div><h3>Conclusion</h3><div>Healthcare schemes are the best strategy to overcome the direct medical cost associated with the management of the disease. Quantifying the medical cost could provide an insight to develop effective policy to counteract the financial toxicity among patients.</div></div>","PeriodicalId":39346,"journal":{"name":"Indian Journal of Tuberculosis","volume":"72 3","pages":"Pages 290-297"},"PeriodicalIF":0.0,"publicationDate":"2025-07-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"140772688","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Primary tonsillar tuberculosis: A challenging clinical diagnosis a cases series 原发性扁桃体结核：一个具有挑战性的临床诊断病例系列

Indian Journal of Tuberculosis Pub Date : 2025-07-01 DOI: 10.1016/j.ijtb.2024.09.003

Sirine Ayadi, Syrine Ghorbel, Mariem Ben ayed, Rania Kharrat, Moncef Sallami, Souha Kallel, Amine Chaabouni, Ilhem Charfeddine

{"title":"Primary tonsillar tuberculosis: A challenging clinical diagnosis a cases series","authors":"Sirine Ayadi, Syrine Ghorbel, Mariem Ben ayed, Rania Kharrat, Moncef Sallami, Souha Kallel, Amine Chaabouni, Ilhem Charfeddine","doi":"10.1016/j.ijtb.2024.09.003","DOIUrl":"10.1016/j.ijtb.2024.09.003","url":null,"abstract":"<div><div>Tonsillar tuberculosis, a rare observed presentation of Mycobacterium tuberculosis affecting the palatine tonsils. Often secondary and associated with concurrent pulmonary tuberculosis, it may clinically manifest as chronic or recurrent tonsillitis, occasionally mimicking malignant conditions. Diagnosis of this condition is often delayed and complex, frequently necessitating histopathological examination for confirmation. Its management predominantly hinges on antitubercular medications.We present two distinct cases of tonsillar tuberculosis. The first case involves a 64-year-old male receiving anti-TNF therapy for ulcerative colitis. He was hospitalized for lateral neck swelling and persistent ulceronecrotic angina despite initial antibiotic treatments. Tonsillar tuberculosis was suspected and confirmed by histopathological analysis. The second case involves a 46-year-old female presenting with right ulceronecrotic angina associated with ipsilateral jugulo-carotid adenopathy. The diagnosis of caseous-follicular tonsillar tuberculosis was confirmed by biopsy. The patient was initiated on antitubercular treatment for a period of 6 months, resulting in a significant improvement in symptoms. Neither patient had pulmonary tuberculosis.</div></div>","PeriodicalId":39346,"journal":{"name":"Indian Journal of Tuberculosis","volume":"72 3","pages":"Pages 438-440"},"PeriodicalIF":0.0,"publicationDate":"2025-07-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144686312","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Clinical characteristics, radiological pointers and outcomes of central nervous system tuberculosis 中枢神经系统结核的临床特点、影像学指标及转归

Indian Journal of Tuberculosis Pub Date : 2025-07-01 DOI: 10.1016/j.ijtb.2024.05.011

Aparna R. Pai , Ashish Rai , Sripadma PV

{"title":"Clinical characteristics, radiological pointers and outcomes of central nervous system tuberculosis","authors":"Aparna R. Pai , Ashish Rai , Sripadma PV","doi":"10.1016/j.ijtb.2024.05.011","DOIUrl":"10.1016/j.ijtb.2024.05.011","url":null,"abstract":"<div><h3>Background</h3><div>Central nervous system tuberculosis (CNS-TB) is a severe and aggressive form of tuberculosis with a high mortality. With early identification and appropriate therapy, it carries a good outcome. Aim: To identify the clinical characteristics, radiological pointers, and outcomes of central nervous system tuberculosis.</div></div><div><h3>Methods</h3><div>Single-center retrospective study was conducted from January 01, 2018 to December 31, 2022 on patients diagnosed with CNS-TB.Adult patients with at least nine months of follow-up were included. Those seropositive for HIV or lost to follow-up before treatment completion were excluded. Variables were expressed as mean with standard deviation, median, and range. Chi-square and student's t-test for qualitative and quantitative variables were used.</div></div><div><h3>Results</h3><div><span>158 records were reviewed, and 56 were excluded. 102 patients were included with 90(88.23 %) cases of tubercular meningitis(TBM) and 12 (11.76 %) cases of isolated tuberculoma<span><span><span>. There were 22(24.44 %) and 63(70.00%) cases of definite and probable tuberculous meningitis. Leptomeningeal enhancement (79.41%)and </span>hydrocephalus (42.22%)were noted commonly. All cases of TBM and </span>tuberculoma completed 9–12 months of anti-tubercular treatment. </span></span>Dexamethasone<span> was given to all patients with TBM for 6–12 weeks. One patient with biopsy-proven isolated tuberculoma received up to 24 months of ATT. Nine patients with TBM died(9/102,8.82 %). Grade III TBM, age >60 years, hydrocephalus,drug-induced hepatitis, and extra-neural tuberculosis were significant in the expired versus survivors comparison (p < 0.05).</span></div></div><div><h3>Conclusions</h3><div>Early identification, appropriate ATT regimen, and duration of treatment are associated with a good outcome in this fatal and disabling disease.</div></div>","PeriodicalId":39346,"journal":{"name":"Indian Journal of Tuberculosis","volume":"72 3","pages":"Pages 319-324"},"PeriodicalIF":0.0,"publicationDate":"2025-07-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144686750","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0