Asian Journal of Pediatric Research最新文献

{"title":"Chronic and Stubborn Leuco-melanoderma in a Child: A Case Study","authors":"C. A. Khabba, M. Asermouh, K. Znati, K. Senouci, L. Benzekri","doi":"10.9734/ajpr/2023/v11i4226","DOIUrl":"https://doi.org/10.9734/ajpr/2023/v11i4226","url":null,"abstract":"Aims: Pityriasis lichenoides chronic is a rare inflammatory dermatosis, unusually hypochromic in dark phototypes. The evolution of the disease is usually benign, but a malignant transformation in mycosis fungoides is reported. You have to know how to think about it when faced with a generalized hypochromic macular eruption in children. \u0000Case Report: We report a case of a 13-years-old child, photo type 4.He presented for 8 months hypochromic macular lesions, located initially at the face. The evolution was marked by the extension at the trunk and the limbs. He was treated for pityriasis versicolor but without improvement. A skin biopsy was then performed, in favor of Pityriasis Lichenoides Chronica (PLC) with a lymphoid infiltrate made up mainly of CD4 T lymphocytes. The child was put on cyclin associated with heliotherapy with a moderate improvement after 3 months of treatment. The patient was followed for 2 years during which he did not present any malignant transformation. \u0000Discussion: Pityriasis Lichenoides is less frequent in the pediatric population.Its etiopathogenesis is still incompletely elucidated. The basic lesion is an erythematous-squamous papule in the trunk. Hypochromic macules can also be observed, either at the cicatricial stage of the disease, or they occur immediately, especially in subjects with dark skin. The histology of PLC reveals perivascular lymphocytic infiltrate in the superficial dermis..The adopted therapeutic is based on heliotherapy or an antibiotic from the macrolide or cyclin family. Evolution towards Mycosis Fungoides has been rarely described. \u0000Conclusion:  PLC is exceptionally hypopigmented from the outset. We report a case of chronic leucomelanodermic pityriasis lichenoides in a child posing a problem of differential diagnosis.","PeriodicalId":393364,"journal":{"name":"Asian Journal of Pediatric Research","volume":"21 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2023-03-06","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"128621444","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Pyoderma Gangrenosum at Uncommon Site in a Pediatric Patient: Case Report and Review of Literature","authors":"Z. Mehsas, S. Sektaoui, B. Boubnane, M. Meziane, N. Ismaili, L. Benzekri, K. Senouci","doi":"10.9734/ajpr/2023/v11i4225","DOIUrl":"https://doi.org/10.9734/ajpr/2023/v11i4225","url":null,"abstract":"A 12-year-old girl presented with three ulcerated lesions on her face that were red, swollen, had advancing borders, and undermined. Despite treatment with intravenous and topical antibiotics, the ulcers did not improve, and cultures showed no growth of organisms. The patient did not have any underlying systemic disease, and a skin biopsy revealed neutrophilic dermatitis. Oral prednisone was started, which resulted in the healing of the lesions. The skin biopsy and positive response to corticosteroids confirmed the diagnosis of Pyoderma Gangrenosum (PG). PG is a rare inflammatory skin condition, and facial lesions are a rare presentation. Early initiation of immunosuppressive therapy is crucial for complete healing and to minimize the significant psychological impact.","PeriodicalId":393364,"journal":{"name":"Asian Journal of Pediatric Research","volume":"12 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2023-03-06","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"125059166","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Interest of Dermoscopy for the Diagnosis of Onychopathy in an Infant","authors":"C. A. Khabba, M. Asermouh, N. Ismaïli, K. Senouci","doi":"10.9734/ajpr/2023/v11i4224","DOIUrl":"https://doi.org/10.9734/ajpr/2023/v11i4224","url":null,"abstract":"Aim: Onychomycosis is a rare pathology in infants which constitutes 15.5% of onychodystrophies in children, especially those with Down syndrome and the immunocompromised. Dermosocpy is an innocuous examination allowing to guide the clinical diagnosis and to avoid invasive examinations. \u0000Presentation of Case: 5-month-old infant presents with thickening of the thumbnail of the left hand with xanthonychia evolving for 20 days without notion of trauma. On clinical examination, xantho-pachyonychia of the thumbnail of the left hand was noted reaching the latero-distal part with subungual hyperkeratosis and peronyxis. Dermoscopy showed yellowish chromonychia, longitudinal striae, subungual hyperkeratosis with jagged edges. The mycological direct examination and culture was in favor of a Candida albicans infection The patient was put on an antifungal cream with improvement after 3 months. \u0000Discussion: The rarity of onychomycosis in infants can be attributed to several factors such as the difference in the structure of the nail plate, less exposure to trauma and rapidity of nail regrowth. The average age is 8 months, the sex ratio at 0.98 and the preferential location is the fingernails. Clinically the nail involvement is of the disto-lateral type with subungual hyperkeratosis and peronyxis. Dermatoscopy is a quick tool showing chromonychia, longitudinal streaks, subungual hyperkeratosis producing a “ruined appearance”, distal onycholysis with jagged edges and linear hemorrhages. Infant onychomycosis is most often of candidal origin (C. albicans). Topical antifungals (ciclopirox) are preferred. \u0000Conclusion: This case is being reported to highlight the important role of dermoscopy in the diagnosis of onychomycosis and thus prevent unnecessary biopsies.","PeriodicalId":393364,"journal":{"name":"Asian Journal of Pediatric Research","volume":"22 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2023-03-04","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"123095877","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Knowledge of Nurses, Attitudes and Practices Related to Blood Transfusion at the Neonatal and Pediatric Intensive Care Unit at University Hospital Mohammed VI Marrakech Morocco","authors":"F. Tahiri, A. Lalaoui, F. Bennaoui, N. Slitine, S. Younous, F. Maoulainine","doi":"10.9734/ajpr/2023/v11i3223","DOIUrl":"https://doi.org/10.9734/ajpr/2023/v11i3223","url":null,"abstract":"Blood transfusion is a therapeutic substitute, saving millions of lives each year. \u0000This practice is common at the neonatal and pediatric intensive care levels. \u0000In order to ensure transfusion safety, control of all stages of the transfusion chain is essential from the collection of blood, its preparation and its biological qualification to the completion of the transfusion procedure and even the follow-up of recipients. \u0000With this in mind, the purpose of this study is to describe the state of knowledge of nursing practice in the area of blood transfusion at the level of neonatal and pediatric intensive care unit at Mohammed VI University Hospital in Marrakech, based on a descriptive approach guided by a frame of reference from the literature review. \u0000We collected our results based on an annotated questionnaire, we found that nurses who had already received specialized training in transfusion rules had a satisfactory level of knowledge compared to those who had not received any training For this we recommend through our survey the importance of continuing training of nursing staff.","PeriodicalId":393364,"journal":{"name":"Asian Journal of Pediatric Research","volume":"12 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2023-02-27","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"131494665","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Risk Factors Associated with Acute Renal Failure in Neonates of a neonatal Intensive Care Unit","authors":"Ana Jaqueline Uribe Barrera, A. Cueva, Claudia Teresa Solano Pérez, Saraí Martínez Llergo, Sinaí Hinojosa Hernández, María del Carmen López Zermeño, María del Carmen Alejandra Hernández Ceruelos, Jesús Carlos Ruvacaba Ledezma","doi":"10.9734/ajpr/2023/v11i3222","DOIUrl":"https://doi.org/10.9734/ajpr/2023/v11i3222","url":null,"abstract":"Objetive: Determining the risk factors associated with acute renal failure in neonates. \u0000Materials and Methods: A case-control study was carried out, in 65 cases of acute renal failure and 65 without acute renal failure in the Intensive Care Unit Neonatals (NICU) of a hospital in Pachuca Hidalgo, Mexico. The variables studied; prematurity, low weight, type I respiratory distress syndrome, perinatal asphyxia, sepsis, necrotizing enterocolitis, administration of vancomycin, amikacin, amphotericin, cefotaxime and water restriction. The information was collected from the data of the clinical records and the analysis was carried out in the Epi-info software. The statistical analysis, it was performed using non-parametric tests such as Chi2 and Fisher's Exact Test. \u0000Results: Denote underweight with an OR 2, 95% CI. from 1.1 to 3.3 and <P 0.05 by Chi2 and Fisher's exact test. For; perinatal asphyxia with OR 2.1, 95% CI. from 1.3 to 3.4 and <P 0.05 through Chi2 and Fisher's exact test. For vancomycin administration OR 4.7, 95% CI. From 2.3 to 9.3 and <P 0.05 by Chi2 and Fisher's exact test. For water restriction OR 2, 95% CI. From 1.2 to 3.3 and <P 0.05 by Chi2 and Fisher's exact test. \u0000Conclusion: A significant association was found between acute renal failure with low weight, perinatal asphyxia, administration of vancomycin and water restriction.","PeriodicalId":393364,"journal":{"name":"Asian Journal of Pediatric Research","volume":"1 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2023-02-17","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"128983569","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Infantile Masturbation-Treated with Anti-Epileptic Drugs: Experience of a Tertiary Care Pediatric Hospital in Bangladesh","authors":"Khadija Rahman, S. Afroze, M. Khaled, M. Khanam, R. Parvin, Sultana Amena Ferdoucy, Sheikh Farjana Sonia","doi":"10.9734/ajpr/2023/v11i3220","DOIUrl":"https://doi.org/10.9734/ajpr/2023/v11i3220","url":null,"abstract":"Aim: This study was aimed to find out the mismanagement of infantile masturbation and the outcome of the cases who were treated with anti-epileptic drugs. \u0000Study Design: Retrospective. \u0000Place and Duration of Study: This study was conducted at outpatient department of Rehabilitation and Neurology unit of Dr. M R Khan Shishu Hospital and Institute of Child Health, Dhaka Bangladesh, between 2013-2022. \u0000Methods: Data were collected from records which included socio-demographic data and clinical features of masturbation in children. Data related to treatment was also collected and their outcome was observed. \u0000Results: Among 50 patients, majority (74%) had age of onset between 12-36 months of age.   Mean age was 43±26 months, the range was between 4 months to 84 months. Female were predominant (60%). Most of the children came from urban area (86%) and belong to nuclear family (78%). They presented with stereotype movement of variable duration and there was no alteration of consciousness. Prone positioning was more frequent than prone to supine position (78% Vs 18%). There was no laboratory and EEG abnormalities among the cases. Thirty two percent patients were treated with anti-epileptic drugs from outside and among them 2 (12%) was given sodium valproate and rest 14 (88%) were treated with phenobarbitone. But there was no clinical improvement in these cases. \u0000Conclusion: Use of anti-epileptic drugs was not associated with any clinical improvement in children with infantile masturbation.","PeriodicalId":393364,"journal":{"name":"Asian Journal of Pediatric Research","volume":"1 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2023-02-16","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"129238813","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Evaluation of Foetal Cardiothoracic Ratio in Normal Pregnancy: Correlation with Gestational Age, Foetal Weight and Established Nomogram","authors":"Peter Chibuzor Oriji, Enefia Kelvin Kiridi, Datonye Christopher Briggs, O. Chibundu, Johnpatrick Uchenna Ugwoegbu, C. Okechukwu, Panebi Yao Bosrotsi, Akaninyene Eseme Ubom, Isaac Joel Abasi, Adedotun Daniel Adesina","doi":"10.9734/ajpr/2023/v11i3221","DOIUrl":"https://doi.org/10.9734/ajpr/2023/v11i3221","url":null,"abstract":"Background: An important sign of congenital heart disease (CHD), myocardial dysfunction and foetal congestive cardiac failure is cardiomegaly, which is detected using the assessment of the cardiothoracic (CT) ratio. \u0000Objective: To evaluate the foetal CT ratio and its relationship with gestational age in the second half of pregnancy, and produce nomograms for the foetal CT ratio. \u0000Subjects and Methods: This descriptive, cross‐sectional study enrolled women with a normal pregnancy in their second and third trimesters at the two tertiary health facilities, one secondary facility and one radiodiagnostic facility in Bayelsa State, Nigeria. The study was conducted from April–December 2022. Pearson's correlation and logistic regression analyses were used to assess the relationship and correlation between the CT ratio, gestational age, and estimated foetal weight. The p<0.05 at 95%CI level of significance was set. \u0000Results: The mean bi-parietal diameter estimated foetal weight and CT diameter ratio was 66.5 ± 18.3 mm, 1.24 ± 0.87 kg and 0.46 ± 0.02 cm respectively. The foetal CT ratio correlates very strongly with estimated gestational age (ɼ = 0.98; p – 0.001), bi-parietal diameter (ɼ = 0.96; p – 0.001), estimated foetal weight (ɼ = 0.92; p – 0.001), Maternal age (ɼ = 0.36; p – 0.001), maternal weight (ɼ = 0.19; p – 0.001) and maternal height (ɼ = 0.20; p – 0.001). \u0000Conclusion: We have demonstrated that there does exist a very strong correlation between the foetal cardiothoracic ratio and the foetal gestational age, biparietal diameter and foetal weight, which slightly, but steadily increased throughout pregnancy.","PeriodicalId":393364,"journal":{"name":"Asian Journal of Pediatric Research","volume":"204 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2023-02-16","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"132148105","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Linear Psoriasis: A Rare and Often Underdiagnosed form of Psoriasis in Children","authors":"S. Sektaoui, Z. Mehsas, N. Ismaili, K. Senouci","doi":"10.9734/ajpr/2023/v11i3219","DOIUrl":"https://doi.org/10.9734/ajpr/2023/v11i3219","url":null,"abstract":"Blaschko-linear psoriasis (PBL) is a rare form of psoriasis that presents as longitudinal lines on the skin, along Blaschko lines. This form of psoriasis is often observed in children and can be difficult to distinguish from other acquired Blaschko linear dermatoses such as inflammatory linear verrucous epidermal nevus (ILVEN) and lichen striatus. The prevalence of PBL is unknown, but it is generally observed in children and is more common in boys than in girls. The clinical and histological similarity of PBL to ILVEN presents a diagnostic challenge. In this case report, we present the case of a 7-year-old child with PBL and discuss the diagnostic and therapeutic aspects of this rare form of psoriasis. We were able to confirm the diagnosis of PBL after treatment with white petroleum jelly and salicylic acid petroleum jelly 5% resulted in a significant improvement of the lesions. Topical treatments, phototherapy, and systemic medications can be used in the case of PBL. It is important to select the most appropriate treatment based on the severity of the lesions, the location, and the patient's tolerance, and to keep in mind that PBL can have long-term effects on the quality of life of patients and their families.","PeriodicalId":393364,"journal":{"name":"Asian Journal of Pediatric Research","volume":"31 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2023-02-15","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"122251915","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Bioelectrical Impedance Analysis for Nutritional Assessment in Children with Chronic Kidney Disease","authors":"Noura Elsayed Elzayat, A. El-barky, Hend Hassan Abd El-Nabi, Rasha Mohamed El-Shafiey, Yousef Fouad Yousef","doi":"10.9734/ajpr/2023/v11i2218","DOIUrl":"https://doi.org/10.9734/ajpr/2023/v11i2218","url":null,"abstract":"Background: Malnutrition and growth failure are major problems among children with chronic kidney disease (CKD). No single metric can describe their nutritional status; therefore, a series of indices and methods are required for evaluation. \u0000Aim of the Work: Evaluation of the nutritional status of children with CKD using dietetic history, anthropometric measurements, biochemical parameters and BIA. \u0000Methods:  This case-control study was conducted on forty CKD children (stages 3-5) from those attending Pediatric Department, Tanta University Hospitals between March 2021 and February 2022 in comparison to forty healthy control children. All were subjected to: dietetic history, anthropometric measurements including (weight, height, body mass index, mid-arm circumference, skin fold thickness), BIA using TANITA Body Composition Analyzer MC-980 MA-N plus III device and laboratory investigations: (CBC, urea, creatinine, ABG, sodium, potassium, phosphorus, calcium, alkaline phosphatase, parathormone hormone, serum proteins, albumin and 24hrs urinary proteins). \u0000Results: CKD children had significantly lower caloric intake and other nutrient consumption including protein, carbohydrate and fat intake (p < 0.05), significantly lower anthropometric measurements including weight, height, body mass index, skinfold thickness and mid-arm circumference than controls (p < 0.05) and significantly lower in BIA measurements including fat mass (FM), fat free mass (FFM), muscle mass (MM), total body water (TBW) and bone mass (BM) than controls. There was significant positive correlation between caloric intake and protein intake with FFM, MM, SMM, BM, TBW and BMR, also there was significant positive correlation between serum albumin and FFM, MM, SMM, BM and TBW in CKD patients. \u0000Conclusions: CKD children had low caloric and protein intake, low body composition parameters, so good nutritional assessment and improvement of their nutritional status is very important. BIA could be used with dietary assessment and anthropometric measurements to achieve more accurate nutritional evaluation in CKD children.","PeriodicalId":393364,"journal":{"name":"Asian Journal of Pediatric Research","volume":"15 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2023-02-13","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"131766801","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"A Case Report and Review of Increased IgE in Patients with Transient Hypogammaglobulinemia of Infancy and Atopic Dermatitis after Normalization of IgG","authors":"T. F. Raham","doi":"10.9734/ajpr/2023/v11i2217","DOIUrl":"https://doi.org/10.9734/ajpr/2023/v11i2217","url":null,"abstract":"The coexistence of a high IgE level and transient hypogammaglobulinemia of infancy ( THI ) with atopic dermatitis (AD) is well known, but the coexistence with a marked serum IgE level ≥ 1000 IU/mL is a rare finding. Literature is scarce regarding IgE levels in patients with THI and AD after treatment with immunoglobulin (Ig). We reported a female infant 8 months old, with THI and severe AD. She was treated with intravenous immunoglobulin (IVIG) infusion after the failure of conventional therapy. Initially, serum levels of IgE were high, and serum levels of IgG were low. After 4 weeks of treatment with IVIG, patient profile showed normalization of IGE and higher elevation in IgG level. The present article is the first to describe a finding of marked IgE elevation (> 1000 IU/mL) after treatment with IVIG. Furthermore, our finding is supported by our review of increased IgE levels in patients with THI and AD who received IG therapy. According to our review different trend of IgE levels in patients who achieved spontaneous normalization of IgG was found.","PeriodicalId":393364,"journal":{"name":"Asian Journal of Pediatric Research","volume":"8 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2023-02-13","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"123984994","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}