Chronic and Stubborn Leuco-melanoderma in a Child: A Case Study

C. A. Khabba, M. Asermouh, K. Znati, K. Senouci, L. Benzekri
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Abstract

Aims: Pityriasis lichenoides chronic is a rare inflammatory dermatosis, unusually hypochromic in dark phototypes. The evolution of the disease is usually benign, but a malignant transformation in mycosis fungoides is reported. You have to know how to think about it when faced with a generalized hypochromic macular eruption in children. Case Report: We report a case of a 13-years-old child, photo type 4.He presented for 8 months hypochromic macular lesions, located initially at the face. The evolution was marked by the extension at the trunk and the limbs. He was treated for pityriasis versicolor but without improvement. A skin biopsy was then performed, in favor of Pityriasis Lichenoides Chronica (PLC) with a lymphoid infiltrate made up mainly of CD4 T lymphocytes. The child was put on cyclin associated with heliotherapy with a moderate improvement after 3 months of treatment. The patient was followed for 2 years during which he did not present any malignant transformation. Discussion: Pityriasis Lichenoides is less frequent in the pediatric population.Its etiopathogenesis is still incompletely elucidated. The basic lesion is an erythematous-squamous papule in the trunk. Hypochromic macules can also be observed, either at the cicatricial stage of the disease, or they occur immediately, especially in subjects with dark skin. The histology of PLC reveals perivascular lymphocytic infiltrate in the superficial dermis..The adopted therapeutic is based on heliotherapy or an antibiotic from the macrolide or cyclin family. Evolution towards Mycosis Fungoides has been rarely described. Conclusion:  PLC is exceptionally hypopigmented from the outset. We report a case of chronic leucomelanodermic pityriasis lichenoides in a child posing a problem of differential diagnosis.
儿童慢性和顽固性白色黑色素瘤:一个案例研究
目的:慢性地衣样糠疹是一种罕见的炎症性皮肤病,在暗光型中表现为异常的低色。疾病的演变通常是良性的,但真菌样真菌病的恶性转化是有报道的。你必须知道当面对儿童全身性褪色黄斑爆发时该如何思考。病例报告:我们报告一例13岁儿童,照片类型4。他表现为8个月的低色斑病变,最初位于面部。进化的标志是躯干和四肢的伸展。他被治疗为花斑糠疹,但没有改善。随后行皮肤活检,证实为慢性地衣样松皮癣(PLC),淋巴细胞浸润主要由CD4 T淋巴细胞组成。患儿接受周期蛋白联合日光疗法,治疗3个月后病情有中度改善。患者随访2年,期间未出现任何恶性转化。讨论:地衣样糠疹在儿科人群中发病率较低。其发病机制尚不完全清楚。基本病变为躯干红斑鳞状丘疹。在疾病的瘢痕阶段也可观察到低色斑,或立即发生,特别是在皮肤黝黑的受试者中。PLC的组织学显示真皮浅层血管周围淋巴细胞浸润。所采用的治疗方法是基于日光疗法或大环内酯或周期素家族的抗生素。向蕈样真菌病的进化很少被描述。结论:PLC从一开始就异常低色素。我们报告一个儿童慢性白斑皮炎的病例,提出了鉴别诊断的问题。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
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