Asian Journal of Pediatric Research最新文献

{"title":"The Rosai-Dorfman Syndrome: A Case Report","authors":"N. Mebrouk, N. Attari, Boutaina Halimi, L. Chtouki, N. Lamalmi, A. Bentahila","doi":"10.9734/ajpr/2023/v12i2236","DOIUrl":"https://doi.org/10.9734/ajpr/2023/v12i2236","url":null,"abstract":"Sinus histiocytosis, also known as Rosaï Dorfman Syndrome (SRD), is a noncancerous condition that causes the growth of large masses of histiocytes in lymph nodes, primarily in the cervical area. Visceral damage is common, and diagnosis is made through histological examination. The cause of SRD is unknown and can occur at any age, even in children. The condition can sometimes improve spontaneously, but large tumor masses can cause compression and damage, particularly if they involve the retro-orbital or epidural areas. In most cases, it is best to avoid treatment, but therapeutic interventions may be necessary for forms of the disease that pose a direct threat or are progressing. Treatment is not standardized and may involve surgery, corticosteroids, immunosuppressants, and/or alpha interferon, depending on the individual case. \u0000We present a case study of a 4-year-old child who had multiple bilateral adenopathies. The diagnosis was verified through a biopsy of the lymph nodes.","PeriodicalId":393364,"journal":{"name":"Asian Journal of Pediatric Research","volume":"17 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2023-04-20","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"132247784","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Atypical Location and Appearance of Chondromyxoid of the Right Iliac Wing Fibroma in a Child","authors":"H. Ziani, Ayoub Ettaj, Yassine Regragui, Nabil Elachhab, A. Bentalha, A. Koraichi, S. Kettani","doi":"10.9734/ajpr/2023/v12i2234","DOIUrl":"https://doi.org/10.9734/ajpr/2023/v12i2234","url":null,"abstract":"Aims: The chondromyxoid tumor is a benign primary bone tumor of cartilaginous differentiation whose location is atypical and rarely described in the literature. \u0000Case Report: A 10 year old child, who consulted the emergency room of the children's hospital of Rabat for a hard and painful swelling of the right iliac fossa, rapidly increasing in volume. Biological tests were normal. The radiography showed a mixed lytic and condensing lesion, heterogeneous, of the right iliac wing, prompting an magnetic resonance imaging (MRI). \u0000Discussion: Chondromyxoid fibroma usually affects young subjects and manifests clinically as pain and swelling. Pathological fractures are common. \u0000On standard radiography, in long bones, there is an eccentric geographic gap, blowing out the cortex. On flat bones such as the iliac bone, the tumor is often polycyclic and mixed, combining condensation and bone lysis. Intratumoral microcalcifications may be encountered. \u0000MRI is the key examination to evoke the diagnosis of chondromyxoid fibroma. \u0000Conclusion: Imaging and in particular MRI plays multiple and fundamental roles in the management of chondromyxoid fibroma. MRI provides diagnostic guidance, particularly in the case of atypical localization.","PeriodicalId":393364,"journal":{"name":"Asian Journal of Pediatric Research","volume":"9 2 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2023-04-13","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"116797548","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Allergy to Argan Oil Confirmed by Oral Challenge Test in Children: Case Report","authors":"Sara Aminou, C. Mahraoui","doi":"10.9734/ajpr/2023/v12i2235","DOIUrl":"https://doi.org/10.9734/ajpr/2023/v12i2235","url":null,"abstract":"Aims: The prevalence of allergy to Argan oil is increasing over the years. It manifests itself in an extremely polymorphous way and responds to all possible routes of exposure: ingestion, contact or inhalation. The provocation test remains the key examination to confirm an allergy to Argan oil. \u0000Presentation of Case: We report the observation of a six-year-old girl presenting with immediate urticaria after ingestion of argan oil. \u0000Discussion: The allergological investigation points to sensitisation of the skin only, with positive prick tests. An oral provocation test was performed and published for the first time to confirm the diagnosis of allergy to argan oil in our patient. \u0000Conclusion: Argan is widely used for its benefits in the cosmetic industry and as a food ingredient. Further studies are needed to explore the mechanisms of sensitisation to Argan oil.","PeriodicalId":393364,"journal":{"name":"Asian Journal of Pediatric Research","volume":"82 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2023-04-13","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"116742954","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Mustard Allergy in Children and Cross-reaction: Case Report","authors":"Sara Aminou, Kaoutar Jellali, C. Mahraoui","doi":"10.9734/ajpr/2023/v12i1233","DOIUrl":"https://doi.org/10.9734/ajpr/2023/v12i1233","url":null,"abstract":"Aims: Food allergy to mustard is often unrecognised in children; however, it deserves early recognition as a potentially severe immunoglobulin e (IgE)--mediated allergy with a risk of anaphylaxis. The aim of this work is to show the value of performing an oral challenge test to confirm the diagnosis of mustard allergy. \u0000Presentation of Case: We report the observation of a child who presented with allergy to yellow mustard with all the allergological work-up performed. \u0000Discussion: The diagnosis of mustard allergy is delicate; on the basis of the clinical history and the food investigation, as mustard is consumed mainly in a masked form. Cross-allergies are common with mugwort, nuts and rosacea. No threshold value for skin tests or specific IgE can be considered sufficient to confirm or not the diagnosis of food allergy or the secondary acquisition of tolerance to mustard. \u0000Conclusion: Oral challenge test is the gold standard for confirming the diagnosis of food allergy; reducing the risk of accidental exposure; validating or not the avoidance diet; and improving quality of life.","PeriodicalId":393364,"journal":{"name":"Asian Journal of Pediatric Research","volume":"9 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2023-04-08","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"132963036","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"An Impressive Case Report of Pachyonychia Congenita and Short Literature Review","authors":"M. Asermouh, C. A. Khabba, Z. Mehsas, K. Senouci","doi":"10.9734/ajpr/2023/v12i1232","DOIUrl":"https://doi.org/10.9734/ajpr/2023/v12i1232","url":null,"abstract":"Aims: Pachyonychia congenita is a rare genodermatosis related to mutations in the genes encoding keratins. Illustrations of such a typical case of this uncommon condition have rarely been seen in the literature, hence the interest of our case report. \u0000Case Report: An 11-year-old girl with a history of parental inbreeding presented with painful bilateral plantar hyperkeratosis associated with significant pachyonychia of the 20 nails and other clinical signs supporting the diagnosis of pachyonychia congenita. \u0000Discussion: Pachyonychia congenita is an autosomal dominant inherited dyskeratosis due to a mutation in the keratin genes k6a, k6b, k6c, k16 or k17.  Clinical signs are dominated by pachonychia and painful palmoplantar keratoderma impacting patients' quality of life. The association with other disorders is possible. To date, treatment remains symptomatic. \u0000Conclusion: The diagnosis of congenital pachyonychia is based on the genetic study of the mutations involved. Nevertheless, a clinical presentation as suggestive as ours allows the immediate diagnosis, thus making this article interesting.","PeriodicalId":393364,"journal":{"name":"Asian Journal of Pediatric Research","volume":"253 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2023-04-07","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"114557366","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Clinical and Dermoscopic Features of Winer's Nodular Solitary Calcinosis","authors":"M. Asermouh, S. Maouni, C. A. Khabba, K. Znati, K. Senouci, M. Meziane","doi":"10.9734/ajpr/2023/v12i1231","DOIUrl":"https://doi.org/10.9734/ajpr/2023/v12i1231","url":null,"abstract":"Aims: Solitary nodular calcinosis of Winer is a rare and benign form of localized idiopathic cutaneous calcinosis. Its dermoscopic features may be useful for early diagnosis, but have never been described in the literature to our knowledge. \u0000Case Report: A 5-year-old child presented to our clinic with a  2 years history of a painless keratotic  and warty nodule located in the helix of the right ear. A wart was suspected and treated without any improvement. Dermoscopy was performed and showed peripheral white deposits suggestive of Winer's calcinosis, motivating an excision whose histological examination confirmed the diagnosis. \u0000Discussion: The subepidermal calcified nodule has been rarely described in the literature. It is not known to be associated with a disorder of phosphocalcium metabolism or other systemic diseases. Pathogenic hypotheses include calcification of preexisting skin structures, mast cell degranulation with secondary calcinosis, or prior trauma. Surgical excision with histopathological confirmation is necessary to show the dermal calcium deposits, which are usually amorphous and granular and may be surrounded by a lymphohistiocytic infiltrate or giant cells. Nevertheless, dermatoscopic evaluation can aid in rendering a timely diagnosis by showing these whitish dermal deposits. \u0000Conclusion: The diagnosis of Winer's nodular calcinosis has always been based on histology, but the dermoscopy described here for the first time is so suggestive that it can be used to save time and exclude other differential diagnoses.","PeriodicalId":393364,"journal":{"name":"Asian Journal of Pediatric Research","volume":"30 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2023-03-31","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"121390015","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Prevalence, Pattern of Disease and Outcome of Children with Sickle Cell Disease Admitted in a Private Health Facility in Southern Nigeria","authors":"B. West, J. Aitafo","doi":"10.9734/ajpr/2023/v12i1230","DOIUrl":"https://doi.org/10.9734/ajpr/2023/v12i1230","url":null,"abstract":"Introduction: Sickle cell disease, an autosomal recessive genetic disorder is characterized by chronic haemolytic anaemia often leading to life-threatening events triggered by acute sickling of red blood cells and microvascular occlusion resulting in frequent admissions. \u0000Aim: To determine the prevalence, pattern of disease and outcome of children with sickle cell disease admitted at a private health facility in southern Nigeria. \u0000Study Design: A retrospective study. \u0000Place and Duration of Study: Study was carried out at a private paediatric hospital in Port Harcourt, Rivers State over a 1-year period. \u0000Methodology: Data was retrieved from the hospitals’ Health Management System. Information obtained were age, sex, diagnosis, indication for transfusion if any, number and types of transfusions, duration of admission, mode of payment of bills and outcome. \u0000Results: Out of 1597 admissions, 59 were children with sickle cell disease giving a prevalence of 3.7%. Males predominated with a Male:Female ratio of 1.7:1, majority were £ 5 years (50.8%) and had insurance (86.4%). Most were admitted during the rainy season (61.0%) and had duration of stay of 1 – 5 days (74.6%). Commonest diseases among these children were sepsis (69.5%), vaso-occlusive crises (52.5%), malaria (52.5%) and severe anaemia/hyper-haemolytic crisis (30.5%). Of the 35.6% who received blood transfusion, majority received sedimented cells (81.0%), were transfused once (71.4%) with majorly blood group O Rhesus D Positive blood (44.8%). One child died with mortality rate of 1.7%. Vaso-occlusive crisis and tonsillitis were significantly observed more in older children ³ 12 years whereas there was no statistically significant association between gender and duration of stay with the pattern of disease. \u0000Conclusion: Sickle cell disease accounted for 3.7% of total admissions with a mortality rate of 1.7%. Sepsis, vaso-occlusive crisis, malaria and severe anaemia/hyper-haemolytic crisis were the commonest diagnosis. Neonatal screening, parental education, patient compliance, vaccinations, regular follow up, and comprehensive health insurance will significantly reduce morbidity and mortality in persons with Sickle cell disease.","PeriodicalId":393364,"journal":{"name":"Asian Journal of Pediatric Research","volume":"2 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2023-03-23","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"130867010","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"The Experience of Mothers in the Makiso Commune in Kisangani (DR Congo) in the Administration of Care to Children Hospitalised in Paediatrics","authors":"P. A. Kangama, J. C. A. Kashundu, J. M. A. Memeyo, R. Ramazani, J. L. B. Lofoka, C. M. Ngolu, P. N. Dikete, B. W. Ndjadi, Bokota Sola Hugues, Bomela Yenga Jacquie","doi":"10.9734/ajpr/2023/v12i1229","DOIUrl":"https://doi.org/10.9734/ajpr/2023/v12i1229","url":null,"abstract":"The study concerns the experience of mothers in the Makiso commune of Kisangani (DR Congo) with regard to the administration of care for children hospitalised in paediatrics, carried out over a period from 15 August to 31 December 2022. It aimed to identify the daily experience of mothers during the administration of care to children, to determine the representation of mothers during the administration of care to children, to demonstrate the satisfaction of mothers during the administration of care to children and to determine the expectation of mothers regarding the administration of care to children. \u0000This is a qualitative phenomenological study in which the study population is made up of parents of children hospitalised in the paediatric department of the General Reference Hospital in Makiso/Kisangani and the sample is made up of four mothers of hospitalised children. The technique of choice for data collection was the unstructured, individual, face-to-face interview. \u0000It was found that the mothers were satisfied with the administration of care on their children by the nurses of the paediatric department and that they naturally expected the recovery of their children's health condition after effective administration of care. \u0000Mothers' experience of child care was positive, as they were actively involved in the smooth and successful care of their hospitalised children.","PeriodicalId":393364,"journal":{"name":"Asian Journal of Pediatric Research","volume":"5 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2023-03-23","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"128425720","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"A Case Report of Achalasia in HIV-Tuberculosis Co-Infected Adolescent","authors":"S. Oninla, F. A. Olagunju, Oyetoke C. Oderanti, Noah O. Aderinto","doi":"10.9734/ajpr/2023/v11i4228","DOIUrl":"https://doi.org/10.9734/ajpr/2023/v11i4228","url":null,"abstract":"Aims: To sensitize clinicians on the need to consider achalasia in HIV infected children presenting with dysphagia. \u0000Presentation of Case: A 14-year-old HIV-infected boy presented with 4years of difficulty and painful swallowing. It was initially to solid food and progressed to liquid diet and water. There were associated intermittent vomiting, weight loss, and recurrent fever. Examination revealed a stunted and chronically ill-looking boy, weighed 22.5Kg and measured 139cm in height, 48.3% and 86.3% of the expected for age respectively. He had generalized lymphadenopathy and whitish patches on the tongue. Initial differential diagnoses were oesophageal candidiasis and achalasia with pulmonary tuberculosis. Chest X-ray and stool gene Xpert confirmed Mycobacterium tuberculosis. The cluster of differentiation (CD) 4 count was 380 cells/ml. He had anti-Koch’s drugs and oral fluconazole for 6 months and 8 weeks respectively, and later highly active antiretroviral therapy. Despite the completion of the fluconazole, the presented symptoms got worsened and the patient could not even take his medications, and his weight dropped to 15kg. Barium swallow and upper GI endoscopy done later confirmed achalasia. He had a successfully modified Heller’s myotomy procedure after which he could eat, drink and take his medications. He was discharged and kept his regular clinic appointments with appreciable weight gain. \u0000Conclusion: Achalasia could occur in HIV-infected children when presented with dysphagia and therefore, a high index of suspicion is needed to make a timely diagnosis to avoid complications and death.","PeriodicalId":393364,"journal":{"name":"Asian Journal of Pediatric Research","volume":"124 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2023-03-17","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"122105360","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Thiamine Deficiency in Exclusive Breastfed Infants with Encephalopathy Attending Govind Ballabh Panth Children Hospital Srinagar, India","authors":"Junaid Mehraj, Y. Khan, K. Ahmad","doi":"10.9734/ajpr/2023/v11i4227","DOIUrl":"https://doi.org/10.9734/ajpr/2023/v11i4227","url":null,"abstract":"Introduction: Thiamine deficiency has historically affected countries and populations consuming milled white rice. Thiamine deficiency in infants can have an acute presentation of encephalopathy with shock with severe metabolic acidosis and death sometimes, if not promptly treated with an intravenous dose of thiamine. \u0000Aims: To study the biochemical deficiency of thiamine in exclusively breastfed infants presenting with encephalopathy and compare them with age-matched controls and to study their clinical course and short-term outcome (till discharge). \u0000Materials and Methods: After dividing infants into four groups based on age in days: (31-60 days; 13 in cases and 8 in controls; 61-90; 4 in cases and 3 in controls; 91-120 days; 2 in cases and none in controls; and >120 days 4 each in cases and controls. This study primarily included the selection of case/control subjects. Two case-control analyses were conducted. In the first one, blood thiamine levels were compared between infants with encephalopathy and without encephalopathy. In the second one, breast milk thiamine levels were compared between infants with encephalopathy and without encephalopathy. Student's independent t-test was used for statistical analysis. \u0000Results: Out of 38 infants, 23 had presented with encephalopathy, and 15 were healthy taken as controls. The mean blood levels of thiamine in infants with encephalopathy in cases were 17.29nmol/l with a Standard deviation of 8.86: the levels ranged between 13.47 and 21.13. The mean value of controls was 51.31, with a Standard deviation of 25.52 ranging between 23.25 and 124.7. The P value was <0.001 and was considered statistically significant. The ROC analysis of the data obtained from thiamine levels obtained in the study 'patient's blood compared with the control group. \u0000Conclusion: Thiamine deficiency can be clinically and biochemically attributed to the presentation of infants with acute encephalopathy.","PeriodicalId":393364,"journal":{"name":"Asian Journal of Pediatric Research","volume":"22 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2023-03-16","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"130229851","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}