Clinical Microbiology Newsletter最新文献_第5页

Recent Advances in Direct Blood Culture Phenotypic Antimicrobial Susceptibility Testing 直接血培养表型药敏试验的最新进展

Clinical Microbiology Newsletter Pub Date : 2022-12-01 DOI: 10.1016/j.clinmicnews.2022.11.005

Elizabeth M. Garrett Ph.D., D(ABMM), April M. Bobenchik Ph.D., D(ABMM)

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A special invitation to authors 对作者的特别邀请

Clinical Microbiology Newsletter Pub Date : 2022-12-01 DOI: 10.1016/j.clinmicnews.2022.11.006

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Monkeypox: Clinical Considerations, Epidemiology, and Laboratory Diagnostics 猴痘:临床考虑、流行病学和实验室诊断

Clinical Microbiology Newsletter Pub Date : 2022-11-15 DOI: 10.1016/j.clinmicnews.2022.11.003

Lucas J. Osborn Ph.D. , Diana Villarreal M.D., Ph.D. , Noah Wald-Dickler M.D. , Jennifer Dien Bard Ph.D.

引用次数: 1

A special invitation to authors 对作者的特别邀请

Clinical Microbiology Newsletter Pub Date : 2022-11-15 DOI: 10.1016/j.clinmicnews.2022.11.004

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Discontinuation of DNA Probes for Identification of Dimorphic Fungi Growing in Culture: What's a Lab To Do? 停止使用DNA探针鉴定培养中的二形真菌:实验室该怎么做?

Clinical Microbiology Newsletter Pub Date : 2022-11-01 DOI: 10.1016/j.clinmicnews.2022.11.001

Tanis C. Dingle , Philippe J. Dufresne

{"title":"Discontinuation of DNA Probes for Identification of Dimorphic Fungi Growing in Culture: What's a Lab To Do?","authors":"Tanis C. Dingle , Philippe J. Dufresne","doi":"10.1016/j.clinmicnews.2022.11.001","DOIUrl":"10.1016/j.clinmicnews.2022.11.001","url":null,"abstract":"<div>The most common dimorphic fungi isolated from clinical specimens in North America are Coccidioides immitis, Coccidioides posadasii, Blastomyces dermatitidis species complex, and Histoplasma capsulatum. These organisms are typically definitively identified at reference or public health laboratories, as they are risk group 3 (RG3) pathogens requiring additional biosafety considerations compared to risk group 2 (RG2) pathogens. Reference and public health laboratories have been using organism-specific DNA probes since the early 1990s as the primary method of confirming the identification of morphologically suspect dimorphic fungi growing in culture. At the end of November 2021, manufacturing of these probes was discontinued, leaving clinical laboratories responsible for dimorphic fungus identification with the task of validating and implementing a new identification method for these pathogens. Here, we discuss alternatives to DNA probes for identification of Coccidioides spp., B. dermatitidis species complex, and H. capsulatum growing in culture, including the strengths and limitations of each method.</div>","PeriodicalId":39211,"journal":{"name":"Clinical Microbiology Newsletter","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2022-11-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"48491573","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 1

Diagnostic Stewardship: the Central Role of Clinical Microbiology Laboratories 诊断管理:临床微生物实验室的中心作用

Clinical Microbiology Newsletter Pub Date : 2022-10-15 DOI: 10.1016/j.clinmicnews.2022.10.004

Daniel A. Green M.D., Maxwell D. Weidmann M.D., Ph.D., Mahavrat S. Srivastava-Malick M.D.

{"title":"Diagnostic Stewardship: the Central Role of Clinical Microbiology Laboratories","authors":"Daniel A. Green M.D., Maxwell D. Weidmann M.D., Ph.D., Mahavrat S. Srivastava-Malick M.D.","doi":"10.1016/j.clinmicnews.2022.10.004","DOIUrl":"10.1016/j.clinmicnews.2022.10.004","url":null,"abstract":"<div>Diagnostic stewardship aims to improve diagnostic test utilization through evidence-based practices to improve care, quality, safety, and costs. Diagnostic stewardship is a collaborative effort that brings together multidisciplinary groups that have a common interest in promoting and ensuring best testing practices. For infectious disease testing, clinical microbiology laboratories are perhaps best positioned within their health care systems to lead these efforts, as they are not only diagnostic experts, but also directly oversee many of the tools and choices available to improve test performance and utilization. While some interventions may not fall under the direct purview of clinical microbiology laboratories, their expertise is nevertheless essential to inform these efforts, as well. Multiple stewardship strategies have been evaluated, providing laboratories with several opportunities to implement evidence-based practice changes to improve quality and outcomes. Further research is needed to continue advancing practice for well-established and emerging tests alike.</div>","PeriodicalId":39211,"journal":{"name":"Clinical Microbiology Newsletter","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2022-10-15","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"49503889","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

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A special invitation to authors 对作者的特别邀请

Clinical Microbiology Newsletter Pub Date : 2022-10-15 DOI: 10.1016/j.clinmicnews.2022.10.005

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A special invitation to authors 对作者的特别邀请

Clinical Microbiology Newsletter Pub Date : 2022-10-01 DOI: 10.1016/j.clinmicnews.2022.10.002

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It's Bordetella, It's Alcaligenes… No, It's Achromobacter! Identification, Antimicrobial Resistance, and Clinical Significance of an Understudied Gram-Negative Rod 是波德特拉菌，是阿尔卡利菌，不，是无色杆菌!一种尚待研究的革兰氏阴性棒的鉴定、耐药性和临床意义

Clinical Microbiology Newsletter Pub Date : 2022-10-01 DOI: 10.1016/j.clinmicnews.2022.10.001

Emily A. Snavely Ph.D., D(ABMM) , Mimi Precit Ph.D., D(ABMM), M(ASCP)CM

{"title":"It's Bordetella, It's Alcaligenes… No, It's Achromobacter! Identification, Antimicrobial Resistance, and Clinical Significance of an Understudied Gram-Negative Rod","authors":"Emily A. Snavely Ph.D., D(ABMM) , Mimi Precit Ph.D., D(ABMM), M(ASCP)CM","doi":"10.1016/j.clinmicnews.2022.10.001","DOIUrl":"10.1016/j.clinmicnews.2022.10.001","url":null,"abstract":"<div>Gram-negative non-fermentative bacilli, such as Achromobacter spp., can be opportunistic pathogens in nosocomial settings. Widely found in nature, Achromobacter spp. cause a broad spectrum of diseases and are best known as emerging opportunistic pathogens in the lungs of cystic fibrosis patients. Importantly, Achromobacter infections represent a diagnostic and clinical challenge. First, clinical laboratories cannot routinely identify Achromobacter isolates reliably to the species level outside of creating and curating a custom mass spectrometry database or using Achromobacter-specific genotypic molecular methods. Additionally, Achromobacter spp. infections are often difficult to treat owing to numerous intrinsic, and to a lesser extent acquired, antimicrobial resistance mechanisms. Treatment decisions are further complicated by discordance between CLSI and EUCAST breakpoints for antimicrobial susceptibility testing of Achromobacter isolates, and collaboration to harmonize these is necessary. Further studies are also needed to define the clinical spectrum of disease and pathogenic potential of many Achromobacter species.</div>","PeriodicalId":39211,"journal":{"name":"Clinical Microbiology Newsletter","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2022-10-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"46914518","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 1

Strongyloides: a Minireview and Update 圆形线虫:一个小回顾和更新

Clinical Microbiology Newsletter Pub Date : 2022-09-15 DOI: 10.1016/j.clinmicnews.2022.09.001

Momar Ndao , Dilhan J. Perera , Kamran Kadkhoda

引用次数: 1