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Clinical Microbiology Newsletter最新文献

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No Small Thing: Clinical Implications of Rapid Syndromic Panel-Based Diagnostic Testing in Children 大事不小:儿童快速综合征组诊断试验的临床意义
Clinical Microbiology Newsletter Pub Date : 2021-09-01 DOI: 10.1016/j.clinmicnews.2021.08.001
Suong Nguyen M.D. Ph.D., Rebecca Same M.D.
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引用次数: 1
A special invitation to authors 对作者的特别邀请
Clinical Microbiology Newsletter Pub Date : 2021-09-01 DOI: 10.1016/j.clinmicnews.2021.08.002
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引用次数: 0
A Review of Diagnostics for Coccidiomycosis 球虫病的诊断方法综述
Clinical Microbiology Newsletter Pub Date : 2021-08-15 DOI: 10.1016/j.clinmicnews.2021.07.003
Matthew Adams D.O. , William Lainhart Ph.D., D(ABMM)
{"title":"A Review of Diagnostics for Coccidiomycosis","authors":"Matthew Adams D.O. ,&nbsp;William Lainhart Ph.D., D(ABMM)","doi":"10.1016/j.clinmicnews.2021.07.003","DOIUrl":"10.1016/j.clinmicnews.2021.07.003","url":null,"abstract":"<div><p><span>Coccidiomycosis<span> is an endemic mycosis that is caused by the dimorphic fungal organisms </span></span><em>Coccidoides immitis</em> and <em>C. posadasii</em><span>. Patients with coccidiomycosis often present for care with community-acquired pneumonia-like illness, and unfortunately, this diagnosis is not commonly at the top of a clinician’s differential, even in areas of endemicity. This review examines the various assays that can be used to diagnose infection with </span><span><em>Coccidioides</em></span><span> spp., including discussion of the performance and interpretation of serological assays, molecular diagnostics, and fungal culture. Additionally, the use of alternative, non-coccidioidal biomarkers to support the diagnosis are discussed.</span></p></div>","PeriodicalId":39211,"journal":{"name":"Clinical Microbiology Newsletter","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2021-08-15","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.1016/j.clinmicnews.2021.07.003","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"46684517","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 3
A special invitation to authors 对作者的特别邀请
Clinical Microbiology Newsletter Pub Date : 2021-08-15 DOI: 10.1016/j.clinmicnews.2021.07.004
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引用次数: 0
Scoping Reviews of the Microbiology Literature: Methods and Payoffs 微生物学文献的范围综述:方法和结果
Clinical Microbiology Newsletter Pub Date : 2021-08-01 DOI: 10.1016/j.clinmicnews.2021.07.001
Matthew L. Rubinstein M.S., MT(ASCP) , J. Scott Parrott Ph.D.
{"title":"Scoping Reviews of the Microbiology Literature: Methods and Payoffs","authors":"Matthew L. Rubinstein M.S., MT(ASCP) ,&nbsp;J. Scott Parrott Ph.D.","doi":"10.1016/j.clinmicnews.2021.07.001","DOIUrl":"10.1016/j.clinmicnews.2021.07.001","url":null,"abstract":"<div><p><span>A scoping review is an approach to evidence synthesis. Its purpose is to provide an overview of the available research evidence without producing a summary answer to a discrete research question. Scoping reviews can be useful for answering expansive questions and identifying information relevant to a given research topic. The utility of scoping reviews is also to inform a systematic review, a knowledge synthesis process that aims to collect, and analyze all evidence that answers a specific research question. Scoping reviews are broadly depicted in the literature; however, the use of scoping review analysis techniques to rigorously prepare a </span>clinical microbiology<span> evidence base for comparison of multicomponent quality improvement interventions has not been explored. Recently, a pilot approach was published, and that approach is summarized here. It combined knowledge synthesis methods to (i) provide a meta-analytic route forward for a systematic review and meta-analysis (SRMA) and (ii) inform the American Society for Microbiology's (ASM's) approach to the production of clinical practice guidelines (CPGs). Further, a generalizable approach for other SRMA investigators who are similarly challenged by an evidence base that involves complex interventions was modeled by an ASM team re-exploring the impact of rapid diagnostics. While the approach is generalized, it is not intended to be prescriptive. The approach may frame or inform further conversation within the clinical microbiology community of practice and anyone reading the ASM CPGs. This article details a fundamental challenge to addressing “intervention complexity” in the clinical microbiology evidence base in the early stages of the CPG process.</span></p></div>","PeriodicalId":39211,"journal":{"name":"Clinical Microbiology Newsletter","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2021-08-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.1016/j.clinmicnews.2021.07.001","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"48965924","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Q Fever: A Troubling Disease and a Challenging Diagnosis 发烧:一种令人不安的疾病和具有挑战性的诊断
Clinical Microbiology Newsletter Pub Date : 2021-08-01 DOI: 10.1016/j.clinmicnews.2021.06.003
Halie K. Miller Ph.D., Rachael A. Priestley B.S., Gilbert J. Kersh Ph.D.
{"title":"Q Fever: A Troubling Disease and a Challenging Diagnosis","authors":"Halie K. Miller Ph.D.,&nbsp;Rachael A. Priestley B.S.,&nbsp;Gilbert J. Kersh Ph.D.","doi":"10.1016/j.clinmicnews.2021.06.003","DOIUrl":"10.1016/j.clinmicnews.2021.06.003","url":null,"abstract":"<div><p><span>Q fever<span> is a disease caused by the bacterial pathogen </span></span><span><em>Coxiella burnetii</em></span><span><span>. This hardy organism can easily spread long distances in the wind, and only a few infectious aerosolized particles are necessary to cause serious illness. Presentations of Q fever disease can be wide ranging, allowing it to masquerade as other illnesses, highlighting the importance of laboratory testing for diagnosis and treatment. This review summarizes Q fever's </span>epidemiology and clinical presentations and presents classical laboratory diagnostic assays and novel approaches to detecting this troubling disease.</span></p></div>","PeriodicalId":39211,"journal":{"name":"Clinical Microbiology Newsletter","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2021-08-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.1016/j.clinmicnews.2021.06.003","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"10263512","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 3
Beta Know Your Haemophilus Resistance Mechanisms 了解你的嗜血杆菌耐药性机制
Clinical Microbiology Newsletter Pub Date : 2021-08-01 DOI: 10.1016/j.clinmicnews.2021.07.002
Christopher D. Doern
{"title":"Beta Know Your Haemophilus Resistance Mechanisms","authors":"Christopher D. Doern","doi":"10.1016/j.clinmicnews.2021.07.002","DOIUrl":"10.1016/j.clinmicnews.2021.07.002","url":null,"abstract":"","PeriodicalId":39211,"journal":{"name":"Clinical Microbiology Newsletter","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2021-08-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.1016/j.clinmicnews.2021.07.002","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"44832049","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Novel ß-Lactamase Inhibitors: New Weapons in the Arms Race against Antimicrobial Resistance 新型ß-内酰胺酶抑制剂:抗菌素耐药性军备竞赛中的新武器
Clinical Microbiology Newsletter Pub Date : 2021-07-15 DOI: 10.1016/j.clinmicnews.2021.06.004
Erin N. Deja Pharm.D., BCPS
{"title":"Novel ß-Lactamase Inhibitors: New Weapons in the Arms Race against Antimicrobial Resistance","authors":"Erin N. Deja Pharm.D., BCPS","doi":"10.1016/j.clinmicnews.2021.06.004","DOIUrl":"10.1016/j.clinmicnews.2021.06.004","url":null,"abstract":"<div><p>Antimicrobial resistance<span><span> is a growing threat in the treatment of infectious diseases. Multidrug-resistant Gram-negative organisms, in particular, have become progressively difficult to manage, due to the increasing diversity and widespread prevalence of β-lactamase enzymes. Novel β-lactamase inhibitors with expanded activity against such enzymes represent a promising strategy to combat Gram-negative resistance. This review discusses the classification of β-lactamases and the history of β-lactamase inhibitor development with a focus on three novel β-lactamase inhibitors—avibactam, </span>relebactam, and vaborbactam—now FDA approved in combination β-lactam/β-lactamase inhibitor products available for clinical use, including their spectrums of inhibition, mechanisms of action, place in therapy, and evidence for use.</span></p></div>","PeriodicalId":39211,"journal":{"name":"Clinical Microbiology Newsletter","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2021-07-15","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.1016/j.clinmicnews.2021.06.004","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"54043045","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 4
A special invitation to authors 对作者的特别邀请
Clinical Microbiology Newsletter Pub Date : 2021-07-15 DOI: 10.1016/j.clinmicnews.2021.06.005
{"title":"A special invitation to authors","authors":"","doi":"10.1016/j.clinmicnews.2021.06.005","DOIUrl":"https://doi.org/10.1016/j.clinmicnews.2021.06.005","url":null,"abstract":"","PeriodicalId":39211,"journal":{"name":"Clinical Microbiology Newsletter","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2021-07-15","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.1016/j.clinmicnews.2021.06.005","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"137336829","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
A special invitation to authors 对作者的特别邀请
Clinical Microbiology Newsletter Pub Date : 2021-06-15 DOI: 10.1016/j.clinmicnews.2021.06.002
{"title":"A special invitation to authors","authors":"","doi":"10.1016/j.clinmicnews.2021.06.002","DOIUrl":"https://doi.org/10.1016/j.clinmicnews.2021.06.002","url":null,"abstract":"","PeriodicalId":39211,"journal":{"name":"Clinical Microbiology Newsletter","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2021-06-15","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.1016/j.clinmicnews.2021.06.002","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"137274502","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
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