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Strongyloides: a Minireview and Update 圆形线虫:一个小回顾和更新
Clinical Microbiology Newsletter Pub Date : 2022-09-15 DOI: 10.1016/j.clinmicnews.2022.09.001
Momar Ndao , Dilhan J. Perera , Kamran Kadkhoda
{"title":"Strongyloides: a Minireview and Update","authors":"Momar Ndao ,&nbsp;Dilhan J. Perera ,&nbsp;Kamran Kadkhoda","doi":"10.1016/j.clinmicnews.2022.09.001","DOIUrl":"10.1016/j.clinmicnews.2022.09.001","url":null,"abstract":"<div><p><span>Strongyloidiasis, typically caused by </span><span><em>Strongyloides stercoralis</em><em>,</em></span><span> is a neglected tropical disease that affects 30 to 100 million people worldwide. Despite the commonly asymptomatic nature of the infection, </span><em>S. stercoralis</em><span> infection of immunocompromised individuals can be lethal. Infected but asymptomatic immunocompetent individuals can develop hyperinfection or disseminated infection if they experience any significant change in their immune status, and recently, cases have been described following the use of corticosteroids to treat COVID-19-related pneumonia. Definitive diagnosis is established via stool examination<span> for rhabditiform larvae; however, contemporary methods, including serologic and molecular testing, are increasingly used as adjunct tests. Importantly, exposed individuals and those expected to become immunosuppressed should be screened and pre-emptively treated before starting immunosuppressive agents to avoid cases of dissemination and hyperinfection.</span></span></p></div>","PeriodicalId":39211,"journal":{"name":"Clinical Microbiology Newsletter","volume":"44 18","pages":"Pages 161-167"},"PeriodicalIF":0.0,"publicationDate":"2022-09-15","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"45439219","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 1
A special invitation to authors 对作者的特别邀请
Clinical Microbiology Newsletter Pub Date : 2022-09-15 DOI: 10.1016/j.clinmicnews.2022.09.002
{"title":"A special invitation to authors","authors":"","doi":"10.1016/j.clinmicnews.2022.09.002","DOIUrl":"https://doi.org/10.1016/j.clinmicnews.2022.09.002","url":null,"abstract":"","PeriodicalId":39211,"journal":{"name":"Clinical Microbiology Newsletter","volume":"44 18","pages":"Page 168"},"PeriodicalIF":0.0,"publicationDate":"2022-09-15","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.sciencedirect.com/science/article/pii/S0196439922000563/pdfft?md5=a68e2fe7eeffbc32144218fc175ade18&pid=1-s2.0-S0196439922000563-main.pdf","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"72228604","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Blood Culture Optimization: Practical Tips 血液培养优化:实用提示
Clinical Microbiology Newsletter Pub Date : 2022-09-01 DOI: 10.1016/j.clinmicnews.2022.08.005
Reem M. Azem , Eric M. Ransom
{"title":"Blood Culture Optimization: Practical Tips","authors":"Reem M. Azem ,&nbsp;Eric M. Ransom","doi":"10.1016/j.clinmicnews.2022.08.005","DOIUrl":"10.1016/j.clinmicnews.2022.08.005","url":null,"abstract":"<div><p><span>Sepsis is a serious medical condition that continues to be a leading cause of hospital admission and mortality worldwide. Blood cultures play a crucial role in identifying the source of sepsis and thus directing appropriate treatment for improved patient outcomes. Blood culture data are not only utilized for patient treatment but also have utility for infection control and epidemiological purposes. An important challenge facing blood culture results and interpretation is contamination, which can have negative effects on patient care and health care costs, including in the </span>clinical microbiology laboratory. This article reviews the process of blood culture collection, from the decision to collect blood cultures to processing, testing, and reporting. Strategies for blood culture optimization are discussed, along with data to support practices that can lead to improved patient care, diagnostic stewardship, and fiscal responsibility.</p></div>","PeriodicalId":39211,"journal":{"name":"Clinical Microbiology Newsletter","volume":"44 17","pages":"Pages 151-160"},"PeriodicalIF":0.0,"publicationDate":"2022-09-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"41987703","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Integration of Histopathology and Clinical Microbiology in the Diagnosis of Infectious Diseases: Focus on Mycoses 组织病理学和临床微生物学在传染病诊断中的整合:以真菌病为重点
Clinical Microbiology Newsletter Pub Date : 2022-08-15 DOI: 10.1016/j.clinmicnews.2022.08.003
Cristina Costales M.D.
{"title":"Integration of Histopathology and Clinical Microbiology in the Diagnosis of Infectious Diseases: Focus on Mycoses","authors":"Cristina Costales M.D.","doi":"10.1016/j.clinmicnews.2022.08.003","DOIUrl":"10.1016/j.clinmicnews.2022.08.003","url":null,"abstract":"<div><p><span><span>Identification and interpretation of microorganisms on histopathology is a skill set critical for both anatomic </span>pathologists and clinical microbiologists. Microorganisms, and fungi in particular, develop structural properties differently within tissue than on an </span>agar plate<span>. For proper diagnoses the interpreter must be familiar with both phenotypes. Here, we review the specifics of fungal growth in tissue, including organism morphology, host reaction, and limitations for accurate histology identification.</span></p></div>","PeriodicalId":39211,"journal":{"name":"Clinical Microbiology Newsletter","volume":"44 16","pages":"Pages 139-149"},"PeriodicalIF":0.0,"publicationDate":"2022-08-15","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"44822837","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 1
A special invitation to authors 对作者的特别邀请
Clinical Microbiology Newsletter Pub Date : 2022-08-15 DOI: 10.1016/j.clinmicnews.2022.08.004
{"title":"A special invitation to authors","authors":"","doi":"10.1016/j.clinmicnews.2022.08.004","DOIUrl":"https://doi.org/10.1016/j.clinmicnews.2022.08.004","url":null,"abstract":"","PeriodicalId":39211,"journal":{"name":"Clinical Microbiology Newsletter","volume":"44 16","pages":"Page 150"},"PeriodicalIF":0.0,"publicationDate":"2022-08-15","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.sciencedirect.com/science/article/pii/S0196439922000502/pdfft?md5=80977d7be236a6555280ba6cd688a9e8&pid=1-s2.0-S0196439922000502-main.pdf","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"72267702","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Can Multidisciplinary Sepsis Teams Help Solve a Global Concern? A Review of the Literature 多学科脓毒症团队可以帮助解决全球关注的问题吗?文献综述
Clinical Microbiology Newsletter Pub Date : 2022-08-01 DOI: 10.1016/j.clinmicnews.2022.08.001
Diane C. Halstead Ph.D., M.S., MASCP, DABMM, FAAM, FCPP
{"title":"Can Multidisciplinary Sepsis Teams Help Solve a Global Concern? A Review of the Literature","authors":"Diane C. Halstead Ph.D., M.S., MASCP, DABMM, FAAM, FCPP","doi":"10.1016/j.clinmicnews.2022.08.001","DOIUrl":"10.1016/j.clinmicnews.2022.08.001","url":null,"abstract":"<div><p><span>The aims of this reviews are to provide a background on sepsis and to discuss the role of multidisciplinary sepsis teams for those who may not provide direct patient care but play an important role in supporting those that manage patients with sepsis. Sepsis, a life-threatening organ dysfunction due to a dysregulated host response to infection, is one of the leading causes of death worldwide. Considered a medical emergency, prompt laboratory results and administration of appropriate antibiotics are critical. Numerous sepsis guidelines have been published, including the use of standardized bundles that can result in reduced mortality and better patient outcomes. Key to successful outcomes are early recognition and appropriate therapy, which is guided by multidisciplinary sepsis intervention teams; rapid laboratory testing, including Gram stains; </span>molecular mass spectrometry; and clinical and electronic early warning surveillance systems that offer a systematic machine learning application to analyze patients’ medical data and send an alert to providers in real time to allow earlier intervention.</p></div>","PeriodicalId":39211,"journal":{"name":"Clinical Microbiology Newsletter","volume":"44 15","pages":"Pages 131-137"},"PeriodicalIF":0.0,"publicationDate":"2022-08-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"43289240","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
A special invitation to authors 对作者的特别邀请
Clinical Microbiology Newsletter Pub Date : 2022-08-01 DOI: 10.1016/j.clinmicnews.2022.08.002
{"title":"A special invitation to authors","authors":"","doi":"10.1016/j.clinmicnews.2022.08.002","DOIUrl":"https://doi.org/10.1016/j.clinmicnews.2022.08.002","url":null,"abstract":"","PeriodicalId":39211,"journal":{"name":"Clinical Microbiology Newsletter","volume":"44 15","pages":"Page 138"},"PeriodicalIF":0.0,"publicationDate":"2022-08-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.sciencedirect.com/science/article/pii/S0196439922000460/pdfft?md5=145310831953c865a8110cfade39b480&pid=1-s2.0-S0196439922000460-main.pdf","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"90034425","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
A special invitation to authors 对作者的特别邀请
Clinical Microbiology Newsletter Pub Date : 2022-07-15 DOI: 10.1016/j.clinmicnews.2022.07.002
{"title":"A special invitation to authors","authors":"","doi":"10.1016/j.clinmicnews.2022.07.002","DOIUrl":"https://doi.org/10.1016/j.clinmicnews.2022.07.002","url":null,"abstract":"","PeriodicalId":39211,"journal":{"name":"Clinical Microbiology Newsletter","volume":"44 14","pages":"Page 130"},"PeriodicalIF":0.0,"publicationDate":"2022-07-15","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.sciencedirect.com/science/article/pii/S0196439922000423/pdfft?md5=d3d14fd67e7896807415620926169f61&pid=1-s2.0-S0196439922000423-main.pdf","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"137386973","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
A 21st Century Appraisal of Whipple’s Disease and Tropheryma whipplei 21世纪对惠普尔病和惠普尔营养瘤的评价
Clinical Microbiology Newsletter Pub Date : 2022-07-15 DOI: 10.1016/j.clinmicnews.2022.07.001
Christopher D. Paddock M.D., M.P.H.T.M. , Florence Fenollar M.D., Ph.D. , Jean-Christophe Lagier M.D., Ph.D. , Didier Raoult M.D. Ph.D.
{"title":"A 21st Century Appraisal of Whipple’s Disease and Tropheryma whipplei","authors":"Christopher D. Paddock M.D., M.P.H.T.M. ,&nbsp;Florence Fenollar M.D., Ph.D. ,&nbsp;Jean-Christophe Lagier M.D., Ph.D. ,&nbsp;Didier Raoult M.D. Ph.D.","doi":"10.1016/j.clinmicnews.2022.07.001","DOIUrl":"10.1016/j.clinmicnews.2022.07.001","url":null,"abstract":"<div><p>Whipple’s disease was formally described more than 100 years ago; nonetheless, only recently have investigators identified, cultivated, and characterized the causative agent, <span><em>Tropheryma whipplei</em></span>, and deciphered some of its complex associations with human hosts. The acquisition of knowledge about <em>T. whipplei</em>, a Gram-positive bacterium in the class <span><em>Actinobacteria</em></span><span><span>, accelerated at an extraordinarily rapid pace during the first two decades of the 21st century, to include the recognition of asymptomatic carriage, localized disease, and acute infections caused by this peculiar bacterium. This review discusses current knowledge of the microbiology and </span>epidemiology of </span><em>T. whipplei</em><span>, the expanding clinical spectrum of disease caused by the pathogen<span>, its treatment, and historical and diagnostic assays that facilitate the diagnosis of the various diseases caused by this enigmatic bacterium.</span></span></p><p>The findings and conclusions in this article are those of the authors and do not necessarily represent the official position of the Centers for Disease Control and Prevention.</p></div>","PeriodicalId":39211,"journal":{"name":"Clinical Microbiology Newsletter","volume":"44 14","pages":"Pages 123-129"},"PeriodicalIF":0.0,"publicationDate":"2022-07-15","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"45633128","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Don't Be a Nit Wit; Know Your Lousy Companions! 不要做一个Nit Wit；认识你的坏朋友！
Clinical Microbiology Newsletter Pub Date : 2022-07-01 DOI: 10.1016/j.clinmicnews.2022.06.004
Blaine A. Mathison B.S., M(ASCP) , Bobbi S. Pritt M.D., M.Sc., DTMH, FCAP
{"title":"Don't Be a Nit Wit; Know Your Lousy Companions!","authors":"Blaine A. Mathison B.S., M(ASCP) ,&nbsp;Bobbi S. Pritt M.D., M.Sc., DTMH, FCAP","doi":"10.1016/j.clinmicnews.2022.06.004","DOIUrl":"10.1016/j.clinmicnews.2022.06.004","url":null,"abstract":"<div><p><span>Lice have been a burden on humans since antiquity. The species implicated in human infestations, the head louse (</span><em>Pediculus humanus capitis</em><span>), body louse (</span><em>Pediculus humanus humanus</em><span>), and pubic louse (</span><em>Pthirus pubis</em><span><span>), are very well adapted to the human host and are readily transmissible between and among individuals. In addition to dermal reactions and social stigmas<span> associated with louse infestations, the body lice are of additional medical and </span></span>public health<span><span><span> concern in the spreading of bacterial agents associated with louse-borne relapsing fever, epidemic typhus, and </span>trench fever. In the United States, </span>pthiriasis, caused by </span></span><em>P. pubis</em><span>, is classified as a sexually transmitted infection. In this review, we provide an update on the taxonomy, epidemiology<span><span>, biology, evolution, clinical importance, treatment and control, diagnosis, and reporting of parasitic </span>human lice.</span></span></p></div>","PeriodicalId":39211,"journal":{"name":"Clinical Microbiology Newsletter","volume":"44 13","pages":"Pages 115-122"},"PeriodicalIF":0.0,"publicationDate":"2022-07-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"48431483","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
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