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A special invitation to authors 对作者的特别邀请
Clinical Microbiology Newsletter Pub Date : 2023-02-01 DOI: 10.1016/j.clinmicnews.2023.01.005
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引用次数: 0
Mycology of Onychomycosis 甲真菌病真菌学
Clinical Microbiology Newsletter Pub Date : 2023-01-15 DOI: 10.1016/j.clinmicnews.2023.01.002
Connie Cañete-Gibas, Nathan P. Wiederhold
{"title":"Mycology of Onychomycosis","authors":"Connie Cañete-Gibas,&nbsp;Nathan P. Wiederhold","doi":"10.1016/j.clinmicnews.2023.01.002","DOIUrl":"10.1016/j.clinmicnews.2023.01.002","url":null,"abstract":"<div><p>Onychomycosis is a fungal infection that can occur within the nails of the fingers and the toes. These infections can lead to discoloration and thickening of the nails, as well as separation of the nails from the bed and their splitting, and ultimately nail destruction. Although predominantly caused by dermatophytes, which have keratinolytic properties, several other groups of fungi can also cause this type of infection, including nondermatophyte molds (both hyaline and dematiaceous) and yeasts, such as <em>Candida</em> species. Proper identification of the etiologic agent is important, as it may influence the treatment of these infections. Here, we review the mycology of onychomycosis and describe recent changes in fungal taxonomy that have occurred with several of these fungi.</p></div>","PeriodicalId":39211,"journal":{"name":"Clinical Microbiology Newsletter","volume":"45 2","pages":"Pages 11-17"},"PeriodicalIF":0.0,"publicationDate":"2023-01-15","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"49118082","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 1
A special invitation to authors 对作者的特别邀请
Clinical Microbiology Newsletter Pub Date : 2023-01-15 DOI: 10.1016/j.clinmicnews.2023.01.003
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引用次数: 0
Sickeningly Sweet: Infectious Complications of Diabetes 令人作呕的甜蜜:糖尿病的传染性并发症
Clinical Microbiology Newsletter Pub Date : 2023-01-01 DOI: 10.1016/j.clinmicnews.2023.01.001
Rong Mei Zhang M.D. , Alexis M. McKee M.D. , Neil W. Anderson M.D.
{"title":"Sickeningly Sweet: Infectious Complications of Diabetes","authors":"Rong Mei Zhang M.D. ,&nbsp;Alexis M. McKee M.D. ,&nbsp;Neil W. Anderson M.D.","doi":"10.1016/j.clinmicnews.2023.01.001","DOIUrl":"10.1016/j.clinmicnews.2023.01.001","url":null,"abstract":"<div><p>Diabetes mellitus is one of the most prevalent chronic diseases in the United States and is associated with a high incidence of infectious complications. These complications lead to increased morbidity, mortality, and utilization of the health care system by a large subset of the worldwide population. The mechanisms contributing to infection in a person living with diabetes are complex and include underlying pathology affecting physiologic functions ranging from adaptive immunity to skin integrity. In this review, we aim to summarize what is known about these pathologies. We highlight how common infections are unique and how certain unique infections are more common in persons with diabetes. Finally, we discuss the clinical presentations and diagnostic considerations pertinent to persons with diabetes.</p></div>","PeriodicalId":39211,"journal":{"name":"Clinical Microbiology Newsletter","volume":"45 1","pages":"Pages 1-10"},"PeriodicalIF":0.0,"publicationDate":"2023-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"49229347","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Don't Be So Negative; Let's Have a Positive Perspective! A Review of Novel Antibiotics Targeting Gram-Positive Bacteria 不要那么消极;让我们有一个积极的观点!针对革兰氏阳性菌的新型抗生素研究进展
Clinical Microbiology Newsletter Pub Date : 2022-12-15 DOI: 10.1016/j.clinmicnews.2022.12.001
Mimi R. Precit Ph.D., D(ABMM), M(ASCP)CM , Emily A. Snavely Ph.D., D(ABMM) , Rachael M. Liesman Ph.D., D(ABMM)
{"title":"Don't Be So Negative; Let's Have a Positive Perspective! A Review of Novel Antibiotics Targeting Gram-Positive Bacteria","authors":"Mimi R. Precit Ph.D., D(ABMM), M(ASCP)CM ,&nbsp;Emily A. Snavely Ph.D., D(ABMM) ,&nbsp;Rachael M. Liesman Ph.D., D(ABMM)","doi":"10.1016/j.clinmicnews.2022.12.001","DOIUrl":"10.1016/j.clinmicnews.2022.12.001","url":null,"abstract":"<div><p><span>Antimicrobial resistance (AMR) is a global health crisis, and the development of new antimicrobials is essential to reducing associated morbidity and mortality. Infections by multi-drug-resistant Gram-negative bacteria have been at the forefront of this AMR </span>public health<span><span> emergency, often overshadowing the importance of novel treatment options for multi-drug-resistant Gram-positive bacterial infections. Here, we introduce and review a number of antimicrobial agents with activity against clinically significant Gram-positive </span>pathogens<span><span>, including difficult-to-treat staphylococci, streptococci<span>, enterococci, and Gram-positive </span></span>anaerobes. We describe antimicrobial agents in late-stage development, those that are newly approved, and those with existing FDA-approved clinical indications for which more recently the FDA expanded approval for novel indications. Overall, the goal of this review is to provide clinical microbiologists, infectious disease physicians, and pharmacists with current, relevant information about novel antibiotic agents effective against Gram-positive bacteria.</span></span></p></div>","PeriodicalId":39211,"journal":{"name":"Clinical Microbiology Newsletter","volume":"44 24","pages":"Pages 219-228"},"PeriodicalIF":0.0,"publicationDate":"2022-12-15","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"43144612","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
A special invitation to authors 对作者的特别邀请
Clinical Microbiology Newsletter Pub Date : 2022-12-15 DOI: 10.1016/j.clinmicnews.2022.12.002
{"title":"A special invitation to authors","authors":"","doi":"10.1016/j.clinmicnews.2022.12.002","DOIUrl":"https://doi.org/10.1016/j.clinmicnews.2022.12.002","url":null,"abstract":"","PeriodicalId":39211,"journal":{"name":"Clinical Microbiology Newsletter","volume":"44 24","pages":"Page 228"},"PeriodicalIF":0.0,"publicationDate":"2022-12-15","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.sciencedirect.com/science/article/pii/S0196439922000927/pdfft?md5=a670bd8a990b961be3a2dc5cfaa9c303&pid=1-s2.0-S0196439922000927-main.pdf","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"90004752","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Recent Advances in Direct Blood Culture Phenotypic Antimicrobial Susceptibility Testing 直接血培养表型药敏试验的最新进展
Clinical Microbiology Newsletter Pub Date : 2022-12-01 DOI: 10.1016/j.clinmicnews.2022.11.005
Elizabeth M. Garrett Ph.D., D(ABMM), April M. Bobenchik Ph.D., D(ABMM)
{"title":"Recent Advances in Direct Blood Culture Phenotypic Antimicrobial Susceptibility Testing","authors":"Elizabeth M. Garrett Ph.D., D(ABMM),&nbsp;April M. Bobenchik Ph.D., D(ABMM)","doi":"10.1016/j.clinmicnews.2022.11.005","DOIUrl":"10.1016/j.clinmicnews.2022.11.005","url":null,"abstract":"<div><p><span>Increasing rates of antibiotic resistance<span> make selecting empiric therapy challenging for the treatment of sepsis and suspected </span></span>bloodstream infections<span><span> (BSIs). The time to initiation of effective therapy for BSIs is critical for positive patient outcomes. Recent advances in rapid diagnostics for the detection of BSIs directly from positive blood culture include rapid organism identification and rapid antimicrobial susceptibility testing (AST). Rapid AST methods include genotypic and phenotypic methods or a combination of both and provide important information to aid in the prompt initiation of effective therapy. Genotypic AST methods allow rapid direct detection of a resistance mechanism but may fail to accurately predict a full susceptibility profile, whereas phenotypic AST provides comprehensive results but is not rapid if conventional methods are used. Efforts to decrease the </span>turnaround time of phenotypic AST are an important advancement for the treatment of BSIs. Here, we review currently available and in-development phenotypic methods for AST directly from positive blood culture and their potential benefits for antimicrobial stewardship and patient care.</span></p></div>","PeriodicalId":39211,"journal":{"name":"Clinical Microbiology Newsletter","volume":"44 23","pages":"Pages 209-216"},"PeriodicalIF":0.0,"publicationDate":"2022-12-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"43479249","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
A special invitation to authors 对作者的特别邀请
Clinical Microbiology Newsletter Pub Date : 2022-12-01 DOI: 10.1016/j.clinmicnews.2022.11.006
{"title":"A special invitation to authors","authors":"","doi":"10.1016/j.clinmicnews.2022.11.006","DOIUrl":"https://doi.org/10.1016/j.clinmicnews.2022.11.006","url":null,"abstract":"","PeriodicalId":39211,"journal":{"name":"Clinical Microbiology Newsletter","volume":"44 23","pages":"Page 218"},"PeriodicalIF":0.0,"publicationDate":"2022-12-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.sciencedirect.com/science/article/pii/S0196439922000885/pdfft?md5=a603bace147d1d335e1cfc5e1432de55&pid=1-s2.0-S0196439922000885-main.pdf","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"136990864","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Monkeypox: Clinical Considerations, Epidemiology, and Laboratory Diagnostics 猴痘:临床考虑、流行病学和实验室诊断
Clinical Microbiology Newsletter Pub Date : 2022-11-15 DOI: 10.1016/j.clinmicnews.2022.11.003
Lucas J. Osborn Ph.D. , Diana Villarreal M.D., Ph.D. , Noah Wald-Dickler M.D. , Jennifer Dien Bard Ph.D.
{"title":"Monkeypox: Clinical Considerations, Epidemiology, and Laboratory Diagnostics","authors":"Lucas J. Osborn Ph.D. ,&nbsp;Diana Villarreal M.D., Ph.D. ,&nbsp;Noah Wald-Dickler M.D. ,&nbsp;Jennifer Dien Bard Ph.D.","doi":"10.1016/j.clinmicnews.2022.11.003","DOIUrl":"10.1016/j.clinmicnews.2022.11.003","url":null,"abstract":"<div><p>Monkeypox virus (MPXV) has garnered recent attention as outbreaks are continually reported outside historic regions of endemicity in Africa. Consequently, MPXV is becoming routinely included in the differential diagnosis of rash illnesses, requiring clinicians and laboratorians alike to quickly adapt to a new public health emergency. This review discusses the epidemiology, clinical presentation, and laboratory testing of MPXV in the context of recent outbreaks.</p></div>","PeriodicalId":39211,"journal":{"name":"Clinical Microbiology Newsletter","volume":"44 22","pages":"Pages 199-208"},"PeriodicalIF":0.0,"publicationDate":"2022-11-15","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9674185/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"40708946","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 1
A special invitation to authors 对作者的特别邀请
Clinical Microbiology Newsletter Pub Date : 2022-11-15 DOI: 10.1016/j.clinmicnews.2022.11.004
{"title":"A special invitation to authors","authors":"","doi":"10.1016/j.clinmicnews.2022.11.004","DOIUrl":"https://doi.org/10.1016/j.clinmicnews.2022.11.004","url":null,"abstract":"","PeriodicalId":39211,"journal":{"name":"Clinical Microbiology Newsletter","volume":"44 22","pages":"Page 208"},"PeriodicalIF":0.0,"publicationDate":"2022-11-15","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.sciencedirect.com/science/article/pii/S0196439922000836/pdfft?md5=edd51abe6427f3707843e1430b6c602b&pid=1-s2.0-S0196439922000836-main.pdf","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"92124160","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
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