Sherrin Jacob, Sana Ahuja, Sufian Zaheer, Mukul Singh
{"title":"Metastasizing pleomorphic adenoma of the parotid gland: A common tumour with a very unusual presentation","authors":"Sherrin Jacob, Sana Ahuja, Sufian Zaheer, Mukul Singh","doi":"10.1016/j.patol.2023.10.002","DOIUrl":"10.1016/j.patol.2023.10.002","url":null,"abstract":"<div><p>Metastasizing pleomorphic adenoma is recognized as a subtype of pleomorphic adenoma in WHO classification 5th edition of salivary glands. The controversy pertaining to the entity is the benign features of the disease even at a metastatic site. We present a rare case of left recurrent pre-auricular swelling in a young male reported as metastasizing pleomorphic adenoma. A nineteen-year-old male presented with left preauricular swelling seven years ago which was diagnosed as pleomorphic adenoma and underwent complete excision of tumour. The tumour recurred twice – two and five years after the surgery. At the second recurrence, the level II neck dissection showed multiple encapsulated deposits of pleomorphic adenoma having similar morphology in the cervical soft tissue with no features of high-grade transformation.</p></div>","PeriodicalId":39194,"journal":{"name":"Revista Espanola de Patologia","volume":"57 2","pages":"Pages 123-127"},"PeriodicalIF":0.0,"publicationDate":"2024-04-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"138613135","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"ChatGPT es un estudiante por encima de la media en la Facultad de Medicina de la Universidad de Zaragoza y un colaborador excelente en la elaboración de material docente","authors":"Clara Cabañuz , Mar García-García","doi":"10.1016/j.patol.2024.01.003","DOIUrl":"10.1016/j.patol.2024.01.003","url":null,"abstract":"<div><h3>Introduction and objective</h3><p>Artificial intelligence is fully present in our lives. In education, the possibilities of its use are endless, both for students and teachers.</p></div><div><h3>Material and methods</h3><p>The capacity of ChatGPT has been explored when solving multiple choice questions based on the exam of the subject «Anatomopathological Diagnostic and Therapeutic Procedures» of the first call of the 2022-23 academic year. In addition, to comparing their results with those of the rest of the students presented the probable causes of incorrect answers have been evaluated. Finally, its ability to formulate new test questions based on specific instructions has been evaluated.</p></div><div><h3>Results</h3><p>ChatGPT correctly answered 47 out of 68 questions, achieving a grade higher than the course average and median. Most failed questions present negative statements, using the words «no», «false» or «incorrect» in their statement. After interacting with it, the program can realize its mistake and change its initial response to the correct answer. Finally, ChatGPT can develop new questions based on a theoretical assumption or a specific clinical simulation.</p></div><div><h3>Conclusions</h3><p>As teachers we are obliged to explore the uses of artificial intelligence and try to use it to our benefit. Carrying out tasks that involve significant consumption, such as preparing multiple-choice questions for content evaluation, is a good example.</p></div>","PeriodicalId":39194,"journal":{"name":"Revista Espanola de Patologia","volume":"57 2","pages":"Pages 91-96"},"PeriodicalIF":0.0,"publicationDate":"2024-04-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"140270811","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Sana Ahuja, Rashi Maheshwari, Saba Naaz, Sufian Zaheer
{"title":"Enteric duplication cysts in paediatric population along with literature review","authors":"Sana Ahuja, Rashi Maheshwari, Saba Naaz, Sufian Zaheer","doi":"10.1016/j.patol.2023.12.003","DOIUrl":"10.1016/j.patol.2023.12.003","url":null,"abstract":"<div><p>The clinical presentation of enteric duplication cysts is dependent on the location of the cyst with symptoms varying from nausea and vomiting to abdominal distension, pain and perforation. Four patients were identified who were diagnosed with enteric duplication cysts within the period from 2019 to 2023. Three of the patients presented with signs of intestinal obstruction-abdominal distension and pain, while one had an antenatally detected abdominal mass. There were three boys and one girl with ages ranging from 4 months to 14 years. Three cases of ileal and one case of caecal duplication cyst were reported. Most of the cases showed ileal/caecal mucosa while one case demonstrated ectopic gastric mucosa. The treatment of these cysts includes surgical excision. Although radiological investigations help in arriving at a provisional diagnosis, the final diagnosis can be confirmed only after histopathological examination. Early treatment prevents complications and results in a good prognosis for the patient.</p></div>","PeriodicalId":39194,"journal":{"name":"Revista Espanola de Patologia","volume":"57 2","pages":"Pages 84-90"},"PeriodicalIF":0.0,"publicationDate":"2024-04-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"140271125","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Diffuse coexpression of thyroid transcription factor-1 and p40 in a non-small cell carcinoma of the lung: Second case in the female population","authors":"Marta Segado Martínez, Gema Ruiz García","doi":"10.1016/j.patol.2023.09.003","DOIUrl":"10.1016/j.patol.2023.09.003","url":null,"abstract":"<div><p>Some non-small cell carcinomas of the lung can express TTF1 and p40 in the same tumor cells. This event has been described in only six cases prior to this one, and only in one other female. It is an extraordinary event that appears as a new entity yet to be defined. The case presented is a woman with a non-small cell lung carcinoma with diffuse coexpression of TTF1 and p40 in the same cells.</p></div>","PeriodicalId":39194,"journal":{"name":"Revista Espanola de Patologia","volume":"57 2","pages":"Pages 120-122"},"PeriodicalIF":0.0,"publicationDate":"2024-04-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"139453607","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Rosalía Sarabia Ochoa, Juan Pablo García de la Torre
{"title":"Tumor espermatocítico variante anaplásica sincrónico bilateral: reporte de una neoplasia infrecuente","authors":"Rosalía Sarabia Ochoa, Juan Pablo García de la Torre","doi":"10.1016/j.patol.2024.01.002","DOIUrl":"10.1016/j.patol.2024.01.002","url":null,"abstract":"<div><p>Spermatocytic tumor is a very rare germ cell testicular neoplasm that accounts for less than 1% of testicular cancers. It generally affects older men with a mean age of 53.6 years (range 19-92 years).</p><p>Spermatocytic tumor is classified within the group of germ cell tumors not related to germ cell neoplasia <em>in situ.</em> It presents clinicopathological characteristics different from classic seminoma and is not considered a variant of the latter. Due to a morphologic overlap with classical seminoma, it was called “sperm cell seminoma” in the past.</p><p>The anaplastic variant of spermatocytic tumor is exceptional, few cases have been described in the literature, it presents an earlier onset compared to spermatocytic tumor and a benign behavior despite showing histological patterns similar to classic seminoma. We present the second case of bilateral synchronous anaplastic spermatocytic tumor, in a young patient treated with orchiectomy and chemotherapy.</p></div>","PeriodicalId":39194,"journal":{"name":"Revista Espanola de Patologia","volume":"57 2","pages":"Pages 146-150"},"PeriodicalIF":0.0,"publicationDate":"2024-04-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"139883264","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Enteroblastic adenocarcinoma of the ampulla of Vater","authors":"Amanda Rodríguez-Villena , Alejandra Veliz-Domínguez , Irene González-García , Ignacio Ruz-Caracuel","doi":"10.1016/j.patol.2024.01.004","DOIUrl":"10.1016/j.patol.2024.01.004","url":null,"abstract":"<div><p>Adenocarcinoma with enteroblastic differentiation is a rare histologic subtype of adenocarcinoma of the gastrointestinal tract that shows unique histologic and immunohistochemical features that resemble fetal intestinal epithelium. This histological subtype has been widely described in the stomach, where it most frequently appears, but, in other locations, it is misdiagnosed because of the poor experience in routine diagnostic setting. Here we present a case of an 87-year-old male with an adenocarcinoma of the ampulla of Vater with enteroblastic differentiation with a literature review of the cases described of this subtype in this location to date. The anatomical peculiarity of the ampulla, joined with the infrequent nature of this histological subtype, makes this case of great interest to aid to better characterize the biological behavior of these tumors.</p></div>","PeriodicalId":39194,"journal":{"name":"Revista Espanola de Patologia","volume":"57 2","pages":"Pages 151-155"},"PeriodicalIF":0.0,"publicationDate":"2024-04-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"140273068","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
João Martins Gama , Rui Caetano Oliveira , Rúben Fonseca , Maria Augusta Cipriano , José Casanova
{"title":"Extraskeletal myxoid chondrosarcoma metastasis to a Meckel's diverticulum adenocarcinoma","authors":"João Martins Gama , Rui Caetano Oliveira , Rúben Fonseca , Maria Augusta Cipriano , José Casanova","doi":"10.1016/j.patol.2023.12.002","DOIUrl":"10.1016/j.patol.2023.12.002","url":null,"abstract":"<div><p>Extraskeletal myxoid chondrosarcoma is a rare soft tissue tumour with a high local and distant metastasis rate and limited response to chemotherapy.</p><p>Meckel's diverticulum is the most frequent congenital anomaly, and it is associated with a considerable risk of malignant transformation.</p><p>In this case report, we describe a 50-year-old female patient with a history of extraskeletal myxoid chondrosarcoma of the lower limb and metastasis to the forearm who went to the emergency department with abdominal pain. The investigations revealed a caecal volvulus. A lesion in the middle third of the ileum was incidentally discovered and removed during surgery.</p><p>Pathology examination revealed a Meckel's diverticulum adenocarcinoma, with metastasis of extraskeletal myxoid chondrosarcoma.</p><p>Resection was complete; however, the patient had diffuse metastatic pulmonary disease and died eight months later due to disease progression.</p><p>This mechanism of tumour-to-tumour metastasis is described in other locations, but, regarding the Meckel's diverticulum, this is a unique situation, previously unreported in the literature.</p></div>","PeriodicalId":39194,"journal":{"name":"Revista Espanola de Patologia","volume":"57 2","pages":"Pages 141-145"},"PeriodicalIF":0.0,"publicationDate":"2024-04-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.sciencedirect.com/science/article/pii/S169988552400014X/pdfft?md5=f108a76f16b6e2afe503e9d7b1fa05de&pid=1-s2.0-S169988552400014X-main.pdf","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"140467028","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Impacto de la patología computacional en Patología","authors":"Antonio Félix Conde Martín","doi":"10.1016/j.patol.2024.03.001","DOIUrl":"https://doi.org/10.1016/j.patol.2024.03.001","url":null,"abstract":"","PeriodicalId":39194,"journal":{"name":"Revista Espanola de Patologia","volume":"57 2","pages":"Pages 75-76"},"PeriodicalIF":0.0,"publicationDate":"2024-04-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"140536209","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
María Teresa Fernández Figueras , Jacques Alzoghby-Abi Chaker , Miriam Fernandez-Parrado , Adriana García Herrera , María Garrido , Miguel Ángel Idoate Gastearena , Mar Llamas-Velasco , Carlos Monteagudo , José Onrubia , Noelia Pérez Muñoz , Juan José Ríos-Martín , José Luis Rodríguez Peralto , Eduardo Rozas Muñoz , Onofre Sanmartín , Ángel Santos-Briz , Carles Saus , José Manuel Suárez Peñaranda , Verónica Velasco Benito , María José Beato Merino , Ángel Fernandez-Flores
{"title":"Principales tipos de quistes en dermatopatología: Parte 2","authors":"María Teresa Fernández Figueras , Jacques Alzoghby-Abi Chaker , Miriam Fernandez-Parrado , Adriana García Herrera , María Garrido , Miguel Ángel Idoate Gastearena , Mar Llamas-Velasco , Carlos Monteagudo , José Onrubia , Noelia Pérez Muñoz , Juan José Ríos-Martín , José Luis Rodríguez Peralto , Eduardo Rozas Muñoz , Onofre Sanmartín , Ángel Santos-Briz , Carles Saus , José Manuel Suárez Peñaranda , Verónica Velasco Benito , María José Beato Merino , Ángel Fernandez-Flores","doi":"10.1016/j.patol.2023.11.007","DOIUrl":"10.1016/j.patol.2023.11.007","url":null,"abstract":"<div><p>This is the second article in a two-part series published in this journal, in which we examine the histopathological characteristics, as well as the differential diagnosis, of the main entities that present as cystic and pseudocystic structures in cutaneous biopsy. In this second article, we address ciliated cutaneous cysts, branchial cysts, Bartholin's cysts, omphalomesenteric cysts, thymic cysts, thyroglossal duct cysts, synovial cysts, and median raphe cysts, as well as mucocele, ganglion, and auricular and digital myxoid pseudocysts.</p></div>","PeriodicalId":39194,"journal":{"name":"Revista Espanola de Patologia","volume":"57 2","pages":"Pages 97-110"},"PeriodicalIF":0.0,"publicationDate":"2024-04-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"140277077","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Irene Iglesias de Ussel Galarreta, Francisco Javier Queipo Gutiérrez
{"title":"Stromal osseous metaplasia in urothelial carcinoma of the bladder: An unusual and challenging feature. A case report","authors":"Irene Iglesias de Ussel Galarreta, Francisco Javier Queipo Gutiérrez","doi":"10.1016/j.patol.2023.09.002","DOIUrl":"10.1016/j.patol.2023.09.002","url":null,"abstract":"<div><p>A 62-year-old male presented with pain and haematuria starting 3 months before. The computed tomography showed focal and mural bladder thickening with ureteropelvic dilatation. The following transurethral bladder resection revealed a high-grade muscle-invasive urothelial carcinoma. In the subsequent cystoprostatectomy we found the same tumour, but adding focal tumour-associated stromal osseous metaplasia.</p><p>Ossifying metaplasia is an extremely rare feature in urothelial carcinoma, with a few reported cases and represents a diagnostic challenge, mimicking radiotherapy-induced sarcoma or sarcomatoid carcinoma.</p></div>","PeriodicalId":39194,"journal":{"name":"Revista Espanola de Patologia","volume":"57 2","pages":"Pages 116-119"},"PeriodicalIF":0.0,"publicationDate":"2024-04-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"139297747","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}