Revista Espanola de Patologia最新文献_第7页

Ser jefe, ¿vale la pena? 担任首席执行官，你觉得值得吗？

Revista Espanola de Patologia Pub Date : 2024-07-01 DOI: 10.1016/j.patol.2024.06.002

Aurelio Ariza

引用次数: 0

Müllerian adenosarcoma with sarcomatous overgrowth and heterologous elements: A case report and literature review 伴有肉瘤过度生长和异种成分的缪勒氏腺肉瘤：病例报告和文献综述

Revista Espanola de Patologia Pub Date : 2024-07-01 DOI: 10.1016/j.patol.2024.03.003

Miguel Ángel Resano Abarzuza , Saúl De Burgos González , Marta Rezola Bajineta , Manuel Moreno Valladares , Yessica Paulina Rodríguez Velandia , Begoña Aguiar Losada , Iraide Bernal Simón , Paloma Cobas Lozano , Irune Ruiz Díaz

{"title":"Müllerian adenosarcoma with sarcomatous overgrowth and heterologous elements: A case report and literature review","authors":"Miguel Ángel Resano Abarzuza , Saúl De Burgos González , Marta Rezola Bajineta , Manuel Moreno Valladares , Yessica Paulina Rodríguez Velandia , Begoña Aguiar Losada , Iraide Bernal Simón , Paloma Cobas Lozano , Irune Ruiz Díaz","doi":"10.1016/j.patol.2024.03.003","DOIUrl":"https://doi.org/10.1016/j.patol.2024.03.003","url":null,"abstract":"<div><p>Uterine mullerian adenosarcoma (MA) is a rare biphasic tumour that accounts for less than 0.5% of uterine neoplasms. The age range of presentation is wide, with the median age in the 5th decade of life. It usually has a good prognosis; however, it worsens when it presents with sarcomatous overgrowth, heterologous elements or infiltrates the myometrium.</p><p>We report the case of a 63-year-old woman presenting with abnormal vaginal bleeding and a sensation of solid material coming out of the cervical canal who was diagnosed with mullerian adenosarcoma with sarcomatous overgrowth (MASO) and presence of heterologous elements after performing a mass biopsy and subsequent hysterectomy.</p><p>We reviewed the literature, focusing especially on the differential diagnoses to be evaluated, as well as the differences in prognosis and treatment according to whether or not they present histologic features of poor prognosis.</p></div>","PeriodicalId":39194,"journal":{"name":"Revista Espanola de Patologia","volume":"57 3","pages":"Pages 176-181"},"PeriodicalIF":0.0,"publicationDate":"2024-07-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141543341","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

In memoriam Dr. Gabriel Toro González (1932-2024) 纪念加布里埃尔-托罗-冈萨雷斯博士（1932-2024 年）

Revista Espanola de Patologia Pub Date : 2024-07-01 DOI: 10.1016/j.patol.2024.06.003

Julio A. Diaz-Perez

引用次数: 0

Duodenitis con cuerpos de Russell. Revisión de la entidad y posibles asociaciones más allá del H. pylori 罗素体十二指肠炎。对幽门螺杆菌以外的实体和可能的关联进行回顾。

Revista Espanola de Patologia Pub Date : 2024-07-01 DOI: 10.1016/j.patol.2024.02.001

Juan José Domínguez Cañete , Irene Platas Moreno

引用次数: 0

Unravelling the enigma: A rare case of primary gastric squamous cell carcinoma with aggressive metastasis 揭开谜底一例罕见的原发性胃鳞状细胞癌伴有侵袭性转移

Revista Espanola de Patologia Pub Date : 2024-07-01 DOI: 10.1016/j.patol.2024.04.002

Adil Aziz Khan, Sana Ahuja, Sufian Zaheer

引用次数: 0

Validation of digital image slides for diagnosis in cervico-vaginal cytology 验证用于宫颈阴道细胞学诊断的数字图像切片

Revista Espanola de Patologia Pub Date : 2024-07-01 DOI: 10.1016/j.patol.2024.03.005

Francisco Tresserra , Gemma Fabra , Olga Luque , Miriam Castélla , Carla Gómez , Carmen Fernández-Cid , Ignacio Rodríguez

{"title":"Validation of digital image slides for diagnosis in cervico-vaginal cytology","authors":"Francisco Tresserra , Gemma Fabra , Olga Luque , Miriam Castélla , Carla Gómez , Carmen Fernández-Cid , Ignacio Rodríguez","doi":"10.1016/j.patol.2024.03.005","DOIUrl":"10.1016/j.patol.2024.03.005","url":null,"abstract":"<div><h3>Objective</h3><p>To test the diagnostic concordance between microscopic (MI) and digital (DG) observation of cervico-vaginal (CV) cytology in a validation study of the technique.</p></div><div><h3>Methods</h3><p>Five cytotechnologists (CT) reviewed 888 routine CV cytology cases from the Cervical Pathology Unit of our center over a 2-week period of time. The cases were first observed by MI and at the end of the day the cases were observed by DG.</p></div><div><h3>Statistical analysis used</h3><p>Agreement calculated using the Kappa index.</p></div><div><h3>Results</h3><p>Most of the diagnoses corresponded to benign (64%) or inflammatory conditions (14%) and 24% corresponded to the intraepithelial lesion or malignancy (ILM) category. The overall kappa coefficient of concordance was strong (0.87). Among the different CTs it was almost perfect in two, strong in two and moderate in one. In 18 cases (10%) there were discrepancies between techniques in the category of ILM. In 10 (56%) cases there was an overdiagnosis in DG and in 8 (44%) an overdiagnosis in MI. Only in two cases, the diagnostic discrepancy exceeded one degree of difference between lesions, and they were ASCUS or AGUS for DG and CIN 2 for MI.</p></div><div><h3>Conclusions</h3><p>In this validation test in which routine cases during a two-week period have been used, observing the cases with both techniques on the same day, we have obtained a strong degree of concordance. The discordances obtained have not been considered relevant.</p></div>","PeriodicalId":39194,"journal":{"name":"Revista Espanola de Patologia","volume":"57 3","pages":"Pages 182-189"},"PeriodicalIF":0.0,"publicationDate":"2024-07-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141393166","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Validation of immunohistochemical overexpression of p16 in the histologic diagnosis of cervical intraepithelial neoplasia grade 2 在宫颈上皮内瘤变 2 级的组织学诊断中验证 p16 的免疫组化过度表达

Revista Espanola de Patologia Pub Date : 2024-07-01 DOI: 10.1016/j.patol.2024.03.004

Ana Forteza , Cristina Vanrell , Gabriel Matheu , Javier Cortés

{"title":"Validation of immunohistochemical overexpression of p16 in the histologic diagnosis of cervical intraepithelial neoplasia grade 2","authors":"Ana Forteza , Cristina Vanrell , Gabriel Matheu , Javier Cortés","doi":"10.1016/j.patol.2024.03.004","DOIUrl":"10.1016/j.patol.2024.03.004","url":null,"abstract":"<div><p>An accurate cytohistologic diagnosis is important to avoid overtreatment of cervical intraepithelial lesions. The three-tiered Cervical Intraepithelial Neoplasia (CIN) classification, grades 1, 2 and 3, despite poor agreement among pathologists in diagnosing CIN2, is still being used. The College of American Pathologists recommended an alternative two-tiered classification that has not yet been universally accepted.</p><p>We review the diagnostic results of 286 biopsies performed by three pathologists using haematoxylin and eosin (H&E) and p16 to establish the level of agreement among the readers.</p><p>Agreement between pathologists in diagnosing CIN2 with H&E was around 45% and improved to 86.7% when interpreting p16 stained biopsies without H&E; agreement with pathologist 3 was lower, around 60%.</p><p>Discrepant results from one pathologist when assessing p16 highlights the decisive influence of individual criteria. P16 has shown to improve agreement between pathologists with previous good agreement, but did not correct it for the third pathologist.</p><p>In equivocal cases, protein p16 is a useful conjunctive tool for a histologic diagnosis.</p></div>","PeriodicalId":39194,"journal":{"name":"Revista Espanola de Patologia","volume":"57 3","pages":"Pages 169-175"},"PeriodicalIF":0.0,"publicationDate":"2024-07-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141046939","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Primary hepatic pleomorphic liposarcoma: Case report and literature review 原发性肝脏多形性脂肪肉瘤：病例报告和文献综述

Revista Espanola de Patologia Pub Date : 2024-04-01 DOI: 10.1016/j.patol.2023.10.003

Ligia Redrobán , Jorge Lara-Endara , Nelson Montalvo , Christian Armijos , Javier Rodríguez-Suárez , Frans Serpa

引用次数: 0

Análisis de la carga laboral en tiempo médico en función del grado de complejidad de las muestras y propuesta de algoritmo para la distribución equitativa del trabajo asistencial en un servicio de anatomía patológica 根据样本的复杂程度分析医疗时间的工作量，并提出在解剖病理科公平分配护理工作的算法。

Revista Espanola de Patologia Pub Date : 2024-04-01 DOI: 10.1016/j.patol.2023.12.001

Angels Quera , Víctor Torres-Padrosa , Adrián Nieto Ortiz

{"title":"Análisis de la carga laboral en tiempo médico en función del grado de complejidad de las muestras y propuesta de algoritmo para la distribución equitativa del trabajo asistencial en un servicio de anatomía patológica","authors":"Angels Quera , Víctor Torres-Padrosa , Adrián Nieto Ortiz","doi":"10.1016/j.patol.2023.12.001","DOIUrl":"10.1016/j.patol.2023.12.001","url":null,"abstract":"<div><h3>Introduction</h3><p>In a pathological anatomy service, the workload in medical time is analyzed based on the complexity of the samples received and its distribution among pathologists is assessed, presenting a new computer algorithm that favors an equitable distribution.</p></div><div><h3>Methods</h3><p>Following the second edition of the Spanish guidelines for the estimation of workload in cytopathology and histopathology (medical time) according to the Spanish Pathology Society-International Academy of Pathology (SEAP-IAP) catalog of samples and procedures, we determined the workload units (UCL) per pathologist and the overall UCL of the service, the average workload of the service (MU factor), the time dedicated by each pathologist to healthcare activity and the optimal number of pathologists according to the workload of the service.</p></div><div><h3>Results</h3><p>We determined 12 197 total annual UCL for the chief pathologist, as well as 14 702 and 13 842 UCL for associate pathologists, with an overall of 40 742 UCL for the whole service. The calculated MU factor is 4.97. The chief pathologist devoted 72.25% of his working day to healthcare activity while associate pathologists dedicated 87.09% and 82.01% of their working hours. The optimal number of pathologists for the service is found to be 3.55.</p></div><div><h3>Conclusions</h3><p>The results demonstrate medical work overload and a non-equitable distribution of UCLs among pathologists. We propose a computer algorithm capable of distributing the workload in an equitable manner. It would be associated with the laboratory information system and take into account the type of specimen, its complexity and the dedication of each pathologist to healthcare activity.</p></div>","PeriodicalId":39194,"journal":{"name":"Revista Espanola de Patologia","volume":"57 2","pages":"Pages 77-83"},"PeriodicalIF":0.0,"publicationDate":"2024-04-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"139888896","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Esofagitis disecante superficial: dos casos de una misma entidad poco frecuente 表层剥离性食道炎：两例罕见病例

Revista Espanola de Patologia Pub Date : 2024-04-01 DOI: 10.1016/j.patol.2023.11.002

Leticia Ollero Domenche, María Elena del Valle Sánchez, Emilio Ignacio Abecia Martínez, Carlos Hörndler Argárate

引用次数: 0