Revista Espanola de Patologia最新文献

Importance of the pathologist in sample management at the sampling site in an interventional pulmonology unit: ROSE, EBUS-TBNA and EBUS-TBLNC 介入肺科科室病理学家在采样点样本管理中的重要性：ROSE、EBUS-TBNA和EBUS-TBLNC

Revista Espanola de Patologia Pub Date : 2025-07-07 DOI: 10.1016/j.patol.2025.100833

Beatriz Agredano-Ávila , Francisco Javier Velasco-Albendea , María Jesús Gil-Belmonte , Juan José Cruz-Rueda , Andrés López-Pardo

引用次数: 0

Metastatic cellular neurothekeoma arising over a vaccination scar: A case report and literature review 转移性细胞神经瘤发生在疫苗接种疤痕：一个病例报告和文献复习

Revista Espanola de Patologia Pub Date : 2025-07-07 DOI: 10.1016/j.patol.2025.100832

Jairo Fuentes-Carrascal , Beatriz Orozco-Sebá , Esperanza Meléndez-Ramírez , Claudia Montoya-Maya , José Tovar-Berardinelli , Juan Marchán-Cárdenas , Jesús Pérez-García

{"title":"Metastatic cellular neurothekeoma arising over a vaccination scar: A case report and literature review","authors":"Jairo Fuentes-Carrascal , Beatriz Orozco-Sebá , Esperanza Meléndez-Ramírez , Claudia Montoya-Maya , José Tovar-Berardinelli , Juan Marchán-Cárdenas , Jesús Pérez-García","doi":"10.1016/j.patol.2025.100832","DOIUrl":"10.1016/j.patol.2025.100832","url":null,"abstract":"<div><div>Cellular neurothekeoma is a rare non-melanocytic skin neoplasm, considered benign and more common in children and young adults, primarily affecting the healthy skin of the head, neck, and scapular region. Based on the morphological findings of the initially reported cases, it was thought to originate from neural sheath cells. Clinical, morphological, and immunohistochemical correlation studies have demonstrated its dermal origin and the absence of neural markers, suggesting a fibrohistiocytic origin, though its histogenesis remains uncertain. They present as slow-growing, self-limiting dermal nodules with exceptional recurrence and very low metastatic potential.</div><div>We present the case of a child with a reddish, firm, asymptomatic nodule on a vaccination scar on the right shoulder, which was excised, after which an ipsilateral axillary mass developed. The histopathological examination of both lesions revealed a neoplasm with morphological and immunohistochemical characteristics consistent with metastatic cutaneous cellular neurothekeoma in a regional lymph node.</div></div>","PeriodicalId":39194,"journal":{"name":"Revista Espanola de Patologia","volume":"58 4","pages":"Article 100832"},"PeriodicalIF":0.0,"publicationDate":"2025-07-07","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144570026","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Identification of germline mutations in DICER1 through routine somatic NGS analysis in various neoplasms 通过常规体细胞NGS分析在各种肿瘤中鉴定DICER1的种系突变

Revista Espanola de Patologia Pub Date : 2025-07-07 DOI: 10.1016/j.patol.2025.100834

Leticia Gracia Sáenz , Svetlana Shalygina , Reyes Roca , Samanta Ortuño , Jose Luis Soto , Maria Tasso , Ana Beatriz Sánchez , Artemio Payá , Cristina Alenda

引用次数: 0

Walking Together Towards Commitment and Excellence in Anatomical Pathology: A Shared Future 共同走向解剖病理学的承诺和卓越：共同的未来

Revista Espanola de Patologia Pub Date : 2025-07-01 DOI: 10.1016/j.patol.2025.100835

Lola Lozano

引用次数: 0

Diagnostic utility of bronchoalveolar lavage in pulmonary disorders 支气管肺泡灌洗在肺部疾病中的诊断价值

Revista Espanola de Patologia Pub Date : 2025-06-12 DOI: 10.1016/j.patol.2025.100830

Niti Sureka, Smriti Sharan, Charanjeet Ahluwalia, Sana Ahuja, Sunil Ranga

{"title":"Diagnostic utility of bronchoalveolar lavage in pulmonary disorders","authors":"Niti Sureka, Smriti Sharan, Charanjeet Ahluwalia, Sana Ahuja, Sunil Ranga","doi":"10.1016/j.patol.2025.100830","DOIUrl":"10.1016/j.patol.2025.100830","url":null,"abstract":"<div><h3>Background</h3><div>Pulmonary diseases represent a significant global health challenge, underscoring the need for accurate diagnostic methods to ensure effective management. Bronchoalveolar lavage (BAL) is an essential diagnostic tool, providing valuable insights into various lung conditions. However, despite its widespread application in pulmonology, limited studies have thoroughly evaluated its diagnostic value.</div></div><div><h3>Materials and methods</h3><div>A retrospective cohort study was conducted over one year to assess the diagnostic utility of BAL. Samples were obtained from patients undergoing BAL as part of their diagnostic workup. Demographic and clinicoradiological data were documented. The BAL fluids were processed and evaluated cytologically, with samples classified into diagnostic categories. In malignant cases, histopathological correlation was performed.</div></div><div><h3>Results</h3><div>A total of 187 BAL fluid samples were analysed, yielding diagnoses that included malignancy (7%), specific infections (6%), inflammatory conditions (43%), and others. BAL demonstrated high efficacy in identifying malignancies (PPV: 85%) and specific infections such as tuberculosis and fungal pneumonia. Histological correlation confirmed the diagnostic accuracy of BAL in malignancies, with a concordance rate of 78%.</div></div><div><h3>Conclusion</h3><div>BAL has proven to be a reliable method for detecting both neoplastic and non-neoplastic lung lesions. Its minimally invasive nature makes it a preferred alternative to needle biopsies, particularly in critically ill patients. Even when findings are nonspecific, BAL helps narrow down differential diagnoses. Additionally, the samples obtained can be used for molecular and microbiological analyses, further enhancing its diagnostic capabilities.</div></div>","PeriodicalId":39194,"journal":{"name":"Revista Espanola de Patologia","volume":"58 3","pages":"Article 100830"},"PeriodicalIF":0.0,"publicationDate":"2025-06-12","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144262540","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Next generation sequencing unravels a gliosarcoma mimicking cerebral osteosarcoma 下一代测序揭示了一种模拟脑骨肉瘤的胶质肉瘤

Revista Espanola de Patologia Pub Date : 2025-05-10 DOI: 10.1016/j.patol.2025.100825

Clara Marti-Macia , Lara Navarro , Teresa San-Miguel , Javier Megias , Javier Carbonell-Zamorano , Moisés Sanchez-Pardo , Esther Roselló-Sastre

引用次数: 0

Papillary thyroid carcinoma with fibromatosis/fasciitis-like/desmoid-type stroma: When to suspect and how to diagnose 甲状腺乳头状癌合并纤维瘤病/筋膜炎样/硬纤维瘤样间质：何时怀疑及如何诊断

Revista Espanola de Patologia Pub Date : 2025-04-19 DOI: 10.1016/j.patol.2025.100819

Judith González-López, Luis Rubio-Martínez, Carlos Zac-Romero, Mireya Prieto-Rodríguez, Nuria Mancheño-Franch

引用次数: 0

Multidisciplinary approach to reach a foetal diagnosis of Walker-Warburg syndrome: From autopsy to genetics and back 多学科方法达到胎儿诊断沃克-沃堡综合征：从尸检到遗传学和背部

Revista Espanola de Patologia Pub Date : 2025-04-18 DOI: 10.1016/j.patol.2025.100827

Anna Sifre-Ruiz , Cristina Esquina-Rodriguez , Africa Manero-Azua , Iñigo Gorostiaga , Guiomar Perez de Nanclares

引用次数: 0

Pathological insights into small cell osteosarcoma: A rare case report highlighting diagnostic approaches with a literature review 病理洞察小细胞骨肉瘤：一个罕见的病例报告强调诊断方法与文献回顾

Revista Espanola de Patologia Pub Date : 2025-04-18 DOI: 10.1016/j.patol.2025.100822

Bhaskar Narayan, Kuldeep Singh, Jeyaseelan Augustine, Aadithya B. Urs

引用次数: 0

Bilateral primary ovarian clear cell carcinoma in a multiparous perimenopausal woman 多产围绝经期妇女双侧原发性卵巢透明细胞癌1例

Revista Espanola de Patologia Pub Date : 2025-04-18 DOI: 10.1016/j.patol.2025.100823

Adil Aziz Khan, Neeti Nagar, Charanjeet Ahluwalia, Sana Ahuja

{"title":"Bilateral primary ovarian clear cell carcinoma in a multiparous perimenopausal woman","authors":"Adil Aziz Khan, Neeti Nagar, Charanjeet Ahluwalia, Sana Ahuja","doi":"10.1016/j.patol.2025.100823","DOIUrl":"10.1016/j.patol.2025.100823","url":null,"abstract":"<div><div>Primary ovarian clear cell carcinoma (OCCC) is a rare subtype of epithelial ovarian carcinoma (EOC), accounting for 5–10% of EOCs in the U.S., with a higher prevalence in East Asia. It is characterized by clear cells forming solid, tubular, or papillary patterns, and presents diagnostic challenges due to its resemblance to renal clear cell carcinomas. Typically affecting nulliparous postmenopausal women, OCCC is associated with high recurrence rates and low sensitivity to platinum-based chemotherapy. We report a case of bilateral primary OCCC in a 45-year-old multiparous woman with no history of endometriosis. She presented with lower abdominal pain and swelling persisting for 7–8 months. Imaging revealed a large, heterogeneous abdominopelvic mass. Surgery included total abdominal hysterectomy with bilateral salpingo-oophorectomy. Histopathological and immunohistochemical analyses confirmed bilateral OCCC, with positive staining for AMACR, Napsin A, and PAX8, and negative results for WT1, ER, and PR. This case highlights the importance of thorough diagnostic evaluation in atypical presentations. The postoperative course was uneventful, and she subsequently received adjuvant therapy.</div></div>","PeriodicalId":39194,"journal":{"name":"Revista Espanola de Patologia","volume":"58 3","pages":"Article 100823"},"PeriodicalIF":0.0,"publicationDate":"2025-04-18","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143843812","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0