Revista Espanola de Patologia最新文献

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In memoriam. Andrés Ribas Barceló (1941-2024) 悼念安德烈斯-里瓦斯-巴塞洛(1941-2024)
Revista Espanola de Patologia Pub Date : 2024-10-01 DOI: 10.1016/j.patol.2024.05.004
Rafael Martínez Girón
{"title":"In memoriam. Andrés Ribas Barceló (1941-2024)","authors":"Rafael Martínez Girón","doi":"10.1016/j.patol.2024.05.004","DOIUrl":"10.1016/j.patol.2024.05.004","url":null,"abstract":"","PeriodicalId":39194,"journal":{"name":"Revista Espanola de Patologia","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2024-10-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141714640","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Unicentric Castleman disease masquerading as a gluteal mass: A diagnostic challenge 伪装成臀部肿块的单中心 Castleman 病:诊断难题
Revista Espanola de Patologia Pub Date : 2024-10-01 DOI: 10.1016/j.patol.2024.06.001
Sana Ahuja , Adil Aziz Khan , Saifullah Khalid , Sufian Zaheer
{"title":"Unicentric Castleman disease masquerading as a gluteal mass: A diagnostic challenge","authors":"Sana Ahuja ,&nbsp;Adil Aziz Khan ,&nbsp;Saifullah Khalid ,&nbsp;Sufian Zaheer","doi":"10.1016/j.patol.2024.06.001","DOIUrl":"10.1016/j.patol.2024.06.001","url":null,"abstract":"<div><div>Castleman disease, a rare lymphoproliferative disorder characterized by non-neoplastic lymph node enlargement, typically presents as nodal involvement, while extranodal manifestations are uncommon. We present a unique case of unicentric Castleman disease localized to the gluteal region in a 27-year-old female. Initially mistaken for a neurogenic or vascular tumour, fine needle aspiration cytology (FNAC) revealed a polymorphous population of lymphoid cells with numerous traversing capillaries suggestive of reactive hyperplasia, possibly Castleman disease, which was later confirmed by histopathology. This case highlights the diagnostic challenges posed by rare extranodal presentations of Castleman disease and underscores the importance of interdisciplinary collaboration in accurate diagnosis and management.</div></div>","PeriodicalId":39194,"journal":{"name":"Revista Espanola de Patologia","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2024-10-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141840069","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Possible benefits, challenges, pitfalls, and future perspective of using ChatGPT in pathology 在病理学中使用 ChatGPT 可能带来的益处、挑战、隐患和未来展望
Revista Espanola de Patologia Pub Date : 2024-07-01 DOI: 10.1016/j.patol.2024.04.003
Durre Aden , Sufian Zaheer , Sabina Khan
{"title":"Possible benefits, challenges, pitfalls, and future perspective of using ChatGPT in pathology","authors":"Durre Aden ,&nbsp;Sufian Zaheer ,&nbsp;Sabina Khan","doi":"10.1016/j.patol.2024.04.003","DOIUrl":"10.1016/j.patol.2024.04.003","url":null,"abstract":"<div><p>The much-hyped artificial intelligence (AI) model called ChatGPT developed by Open AI can have great benefits for physicians, especially pathologists, by saving time so that they can use their time for more significant work. Generative AI is a special class of AI model, which uses patterns and structures learned from existing data and can create new data. Utilizing ChatGPT in Pathology offers a multitude of benefits, encompassing the summarization of patient records and its promising prospects in Digital Pathology, as well as its valuable contributions to education and research in this field. However, certain roadblocks need to be dealt like integrating ChatGPT with image analysis which will act as a revolution in the field of pathology by increasing diagnostic accuracy and precision. The challenges with the use of ChatGPT encompass biases from its training data, the need for ample input data, potential risks related to bias and transparency, and the potential adverse outcomes arising from inaccurate content generation. Generation of meaningful insights from the textual information which will be efficient in processing different types of image data, such as medical images, and pathology slides. Due consideration should be given to ethical and legal issues including bias.</p></div>","PeriodicalId":39194,"journal":{"name":"Revista Espanola de Patologia","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2024-07-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141415570","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Giant thigh hemosiderotic/aneurysmal dermatofibroma: Case report with radiologic–pathologic correlation 巨大的大腿血纤维瘤/动脉瘤性皮纤维瘤:病例报告与放射学病理学相关性
Revista Espanola de Patologia Pub Date : 2024-07-01 DOI: 10.1016/j.patol.2024.04.001
Eva Manuela Pena-Burgos , Carolina D’Angelo , María Cristina Díez-Corral , Elena Sánchez Villanueva , Mar Tapia-Viñe , Jose Juan Pozo-Kreilinger , Dolores Vélez Velázquez
{"title":"Giant thigh hemosiderotic/aneurysmal dermatofibroma: Case report with radiologic–pathologic correlation","authors":"Eva Manuela Pena-Burgos ,&nbsp;Carolina D’Angelo ,&nbsp;María Cristina Díez-Corral ,&nbsp;Elena Sánchez Villanueva ,&nbsp;Mar Tapia-Viñe ,&nbsp;Jose Juan Pozo-Kreilinger ,&nbsp;Dolores Vélez Velázquez","doi":"10.1016/j.patol.2024.04.001","DOIUrl":"10.1016/j.patol.2024.04.001","url":null,"abstract":"<div><p>Hemosiderotic/aneurysmal variant of dermatofibroma (DF) is infrequent and may be misdiagnosed with malignant lesions. We report the case of a giant (7.6<!--> <!-->cm) subcutaneous hemosiderotic/aneurysmal DF (H/ADF) of the thigh in a 53-year-old female patient. Internal arterial and venous hypervascularity was seen by spectral Doppler ultrasound. Magnetic resonance image showed a discrete homogeneous hypointense in T1-weighted images (WI) and T2-WI mass, with hyperintense areas in fat-suppressed T2-WI. The histology revealed a monotonous fusocelular proliferation without atypia, positive for CD163, factor XIIIa and CD10. Widely distributed hemosiderin pigment and two blood-filled pseudovascular spaces lacking endothelial lining were present. H/ADF was diagnosed. The mass was removed but surgical margins were affected. The patient did not present local relapse or distant metastasis. H/ADF are unusual cutaneous soft tissue tumours that can be clinically, radiologically and histopathologically confused with malignant lesions such as melanomas, vascular lesions or sarcomas, especially in giant cases.</p></div>","PeriodicalId":39194,"journal":{"name":"Revista Espanola de Patologia","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2024-07-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141141767","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Characterization of spinal hemangioblastomas in patients with and without von Hippel-Lindau, and YAP expression 有冯-希佩尔-林道和无冯-希佩尔-林道患者脊柱血管母细胞瘤的特征及 YAP 表达
Revista Espanola de Patologia Pub Date : 2024-07-01 DOI: 10.1016/j.patol.2024.03.002
Ana-Laura Calderón-Garcidueñas , Steven-Andrés Piña-Ballantyne , Eunice-Jazmín Espinosa-Aguilar , Rebeca de Jesús Ramos-Sánchez
{"title":"Characterization of spinal hemangioblastomas in patients with and without von Hippel-Lindau, and YAP expression","authors":"Ana-Laura Calderón-Garcidueñas ,&nbsp;Steven-Andrés Piña-Ballantyne ,&nbsp;Eunice-Jazmín Espinosa-Aguilar ,&nbsp;Rebeca de Jesús Ramos-Sánchez","doi":"10.1016/j.patol.2024.03.002","DOIUrl":"10.1016/j.patol.2024.03.002","url":null,"abstract":"<div><h3>Introduction</h3><p>Hemangioblastoma (HB) is a benign tumor of the central nervous system, associated with von Hippel-Lindau disease (VHL), or sporadic. The aim of this study was to compare and examine the clinical–pathological profile of patients with spinal hemangioblastoma and YAP expression.</p></div><div><h3>Methods</h3><p>A retrospective, descriptive, comparative study. All patients who underwent surgery for spinal HB between 2016 and 2023 were included. Clinical and radiological data were collected and analyzed. An immunohistochemistry panel including NeuN, neurofilaments (NF), and YAP-1, was performed.</p></div><div><h3>Results</h3><p>Nine patients were studied, six women and three men. Four patients had previously diagnosed VHL. The tumor location included: four cervical (44.44%), two thoracic (22.22%), two pontine with cervical extension (22.22%) and one patient with two lesions, one cervical and one thoracic (11.11%). Non-significant clinical differences were identified between VHL and sporadic patients. Imaging evidenced seven extramedullary and three intramedullary tumors.</p><p>Histologically, intra-tumoral and perivascular axonal tracts were observed in all cases. One third of the tumors (two with VHL and one sporadic) presented extramedullary hematopoiesis. Seven cases (77.8%) expressed nuclear YAP (three with VHL and four sporadic HBs). The surgical outcome was good and only one patient with VHL undergoing subtotal resection had recurrence.</p></div><div><h3>Conclusions</h3><p>Spinal HBs can be associated with VHL or be sporadic. To the best of our knowledge, this is the first study to describe YAP expression in HB. It is important to investigate the involvement of the Hippo pathway in HBs as a possible therapeutic target.</p></div>","PeriodicalId":39194,"journal":{"name":"Revista Espanola de Patologia","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2024-07-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"140791654","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Telangiectatic osteosarcoma of the mandible—A rare case report and an insight into differential diagnosis 下颌骨的扩张性骨肉瘤--罕见病例报告和鉴别诊断启示
Revista Espanola de Patologia Pub Date : 2024-07-01 DOI: 10.1016/j.patol.2024.05.001
Priya Kumar , Bhaskar Narayan , Aadithya B. Urs , Sujata Mohanty , Jeyaseelan Augustine , Paminder Singh , Nita Khurana
{"title":"Telangiectatic osteosarcoma of the mandible—A rare case report and an insight into differential diagnosis","authors":"Priya Kumar ,&nbsp;Bhaskar Narayan ,&nbsp;Aadithya B. Urs ,&nbsp;Sujata Mohanty ,&nbsp;Jeyaseelan Augustine ,&nbsp;Paminder Singh ,&nbsp;Nita Khurana","doi":"10.1016/j.patol.2024.05.001","DOIUrl":"10.1016/j.patol.2024.05.001","url":null,"abstract":"<div><p>Telangiectatic osteosarcoma (TOS) is a rare variant of osteosarcoma that typically affects young individuals and long bones. The case under discussion was seen in the mandible of a 57-year-old female and had rapidly grown in size within a week. Microscopically, the tumour was characterised by large vascular cavities surrounded by anaplastic cells. Thin lacy tumour osteoid was observed at various foci. Abundant multinucleated osteoclastic giant cells along with areas of necrosis were also noted. The tumour cells were positive for SATB2, while negative for Cytokeratin AE1/3, CD 34. Ki-67 positivity was observed in more than 50% of tumour cells. A diagnosis of high grade telangiectatic osteosarcoma was thus made.</p></div>","PeriodicalId":39194,"journal":{"name":"Revista Espanola de Patologia","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2024-07-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141396881","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Ser jefe, ¿vale la pena? 担任首席执行官,你觉得值得吗?
Revista Espanola de Patologia Pub Date : 2024-07-01 DOI: 10.1016/j.patol.2024.06.002
Aurelio Ariza
{"title":"Ser jefe, ¿vale la pena?","authors":"Aurelio Ariza","doi":"10.1016/j.patol.2024.06.002","DOIUrl":"https://doi.org/10.1016/j.patol.2024.06.002","url":null,"abstract":"","PeriodicalId":39194,"journal":{"name":"Revista Espanola de Patologia","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2024-07-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141543428","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Müllerian adenosarcoma with sarcomatous overgrowth and heterologous elements: A case report and literature review 伴有肉瘤过度生长和异种成分的缪勒氏腺肉瘤:病例报告和文献综述
Revista Espanola de Patologia Pub Date : 2024-07-01 DOI: 10.1016/j.patol.2024.03.003
Miguel Ángel Resano Abarzuza , Saúl De Burgos González , Marta Rezola Bajineta , Manuel Moreno Valladares , Yessica Paulina Rodríguez Velandia , Begoña Aguiar Losada , Iraide Bernal Simón , Paloma Cobas Lozano , Irune Ruiz Díaz
{"title":"Müllerian adenosarcoma with sarcomatous overgrowth and heterologous elements: A case report and literature review","authors":"Miguel Ángel Resano Abarzuza ,&nbsp;Saúl De Burgos González ,&nbsp;Marta Rezola Bajineta ,&nbsp;Manuel Moreno Valladares ,&nbsp;Yessica Paulina Rodríguez Velandia ,&nbsp;Begoña Aguiar Losada ,&nbsp;Iraide Bernal Simón ,&nbsp;Paloma Cobas Lozano ,&nbsp;Irune Ruiz Díaz","doi":"10.1016/j.patol.2024.03.003","DOIUrl":"https://doi.org/10.1016/j.patol.2024.03.003","url":null,"abstract":"<div><p>Uterine mullerian adenosarcoma (MA) is a rare biphasic tumour that accounts for less than 0.5% of uterine neoplasms. The age range of presentation is wide, with the median age in the 5th decade of life. It usually has a good prognosis; however, it worsens when it presents with sarcomatous overgrowth, heterologous elements or infiltrates the myometrium.</p><p>We report the case of a 63-year-old woman presenting with abnormal vaginal bleeding and a sensation of solid material coming out of the cervical canal who was diagnosed with mullerian adenosarcoma with sarcomatous overgrowth (MASO) and presence of heterologous elements after performing a mass biopsy and subsequent hysterectomy.</p><p>We reviewed the literature, focusing especially on the differential diagnoses to be evaluated, as well as the differences in prognosis and treatment according to whether or not they present histologic features of poor prognosis.</p></div>","PeriodicalId":39194,"journal":{"name":"Revista Espanola de Patologia","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2024-07-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141543341","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
In memoriam Dr. Gabriel Toro González (1932-2024) 纪念加布里埃尔-托罗-冈萨雷斯博士(1932-2024 年)
Revista Espanola de Patologia Pub Date : 2024-07-01 DOI: 10.1016/j.patol.2024.06.003
Julio A. Diaz-Perez
{"title":"In memoriam Dr. Gabriel Toro González (1932-2024)","authors":"Julio A. Diaz-Perez","doi":"10.1016/j.patol.2024.06.003","DOIUrl":"https://doi.org/10.1016/j.patol.2024.06.003","url":null,"abstract":"","PeriodicalId":39194,"journal":{"name":"Revista Espanola de Patologia","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2024-07-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.sciencedirect.com/science/article/pii/S1699885524000527/pdfft?md5=c3f351c55fa6e3479440822af94ce5c1&pid=1-s2.0-S1699885524000527-main.pdf","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141543429","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Duodenitis con cuerpos de Russell. Revisión de la entidad y posibles asociaciones más allá del H. pylori 罗素体十二指肠炎。对幽门螺杆菌以外的实体和可能的关联进行回顾。
Revista Espanola de Patologia Pub Date : 2024-07-01 DOI: 10.1016/j.patol.2024.02.001
Juan José Domínguez Cañete , Irene Platas Moreno
{"title":"Duodenitis con cuerpos de Russell. Revisión de la entidad y posibles asociaciones más allá del H. pylori","authors":"Juan José Domínguez Cañete ,&nbsp;Irene Platas Moreno","doi":"10.1016/j.patol.2024.02.001","DOIUrl":"10.1016/j.patol.2024.02.001","url":null,"abstract":"<div><p>Plasma cells known as “Mott cells” present non-secretable accumulations of immunoglobulins called “Russell bodies”. Its presence is related to hematological neoplasms, but it can appear in chronic inflammatory processes. The most common occurrence within the digestive tract is the gastric antrum associated with <em>H. pylori</em> infection. Our patient is added the rare extragastric cases where the association with <em>H. pylori</em> is inconsistent. We have found a frequent appearance of lower digestive and urological neoplasms in relation to these cases, justified by the expression of circulating cytokines in the tumor area that lead to the overactivation of plasma cells. This possible association could lead us to know data about the tumor environment and serve us for early diagnosis or future therapeutic targets.</p></div>","PeriodicalId":39194,"journal":{"name":"Revista Espanola de Patologia","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2024-07-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"140783050","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
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