Revista Espanola de Patologia最新文献_第3页

Unravelling the enigma: A rare case of primary gastric squamous cell carcinoma with aggressive metastasis 揭开谜底一例罕见的原发性胃鳞状细胞癌伴有侵袭性转移

Revista Espanola de Patologia Pub Date : 2024-07-01 DOI: 10.1016/j.patol.2024.04.002

Adil Aziz Khan, Sana Ahuja, Sufian Zaheer

引用次数: 0

Validation of digital image slides for diagnosis in cervico-vaginal cytology 验证用于宫颈阴道细胞学诊断的数字图像切片

Revista Espanola de Patologia Pub Date : 2024-07-01 DOI: 10.1016/j.patol.2024.03.005

Francisco Tresserra , Gemma Fabra , Olga Luque , Miriam Castélla , Carla Gómez , Carmen Fernández-Cid , Ignacio Rodríguez

{"title":"Validation of digital image slides for diagnosis in cervico-vaginal cytology","authors":"Francisco Tresserra , Gemma Fabra , Olga Luque , Miriam Castélla , Carla Gómez , Carmen Fernández-Cid , Ignacio Rodríguez","doi":"10.1016/j.patol.2024.03.005","DOIUrl":"10.1016/j.patol.2024.03.005","url":null,"abstract":"<div><h3>Objective</h3><p>To test the diagnostic concordance between microscopic (MI) and digital (DG) observation of cervico-vaginal (CV) cytology in a validation study of the technique.</p></div><div><h3>Methods</h3><p>Five cytotechnologists (CT) reviewed 888 routine CV cytology cases from the Cervical Pathology Unit of our center over a 2-week period of time. The cases were first observed by MI and at the end of the day the cases were observed by DG.</p></div><div><h3>Statistical analysis used</h3><p>Agreement calculated using the Kappa index.</p></div><div><h3>Results</h3><p>Most of the diagnoses corresponded to benign (64%) or inflammatory conditions (14%) and 24% corresponded to the intraepithelial lesion or malignancy (ILM) category. The overall kappa coefficient of concordance was strong (0.87). Among the different CTs it was almost perfect in two, strong in two and moderate in one. In 18 cases (10%) there were discrepancies between techniques in the category of ILM. In 10 (56%) cases there was an overdiagnosis in DG and in 8 (44%) an overdiagnosis in MI. Only in two cases, the diagnostic discrepancy exceeded one degree of difference between lesions, and they were ASCUS or AGUS for DG and CIN 2 for MI.</p></div><div><h3>Conclusions</h3><p>In this validation test in which routine cases during a two-week period have been used, observing the cases with both techniques on the same day, we have obtained a strong degree of concordance. The discordances obtained have not been considered relevant.</p></div>","PeriodicalId":39194,"journal":{"name":"Revista Espanola de Patologia","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2024-07-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141393166","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Validation of immunohistochemical overexpression of p16 in the histologic diagnosis of cervical intraepithelial neoplasia grade 2 在宫颈上皮内瘤变 2 级的组织学诊断中验证 p16 的免疫组化过度表达

Revista Espanola de Patologia Pub Date : 2024-07-01 DOI: 10.1016/j.patol.2024.03.004

Ana Forteza , Cristina Vanrell , Gabriel Matheu , Javier Cortés

{"title":"Validation of immunohistochemical overexpression of p16 in the histologic diagnosis of cervical intraepithelial neoplasia grade 2","authors":"Ana Forteza , Cristina Vanrell , Gabriel Matheu , Javier Cortés","doi":"10.1016/j.patol.2024.03.004","DOIUrl":"10.1016/j.patol.2024.03.004","url":null,"abstract":"<div><p>An accurate cytohistologic diagnosis is important to avoid overtreatment of cervical intraepithelial lesions. The three-tiered Cervical Intraepithelial Neoplasia (CIN) classification, grades 1, 2 and 3, despite poor agreement among pathologists in diagnosing CIN2, is still being used. The College of American Pathologists recommended an alternative two-tiered classification that has not yet been universally accepted.</p><p>We review the diagnostic results of 286 biopsies performed by three pathologists using haematoxylin and eosin (H&E) and p16 to establish the level of agreement among the readers.</p><p>Agreement between pathologists in diagnosing CIN2 with H&E was around 45% and improved to 86.7% when interpreting p16 stained biopsies without H&E; agreement with pathologist 3 was lower, around 60%.</p><p>Discrepant results from one pathologist when assessing p16 highlights the decisive influence of individual criteria. P16 has shown to improve agreement between pathologists with previous good agreement, but did not correct it for the third pathologist.</p><p>In equivocal cases, protein p16 is a useful conjunctive tool for a histologic diagnosis.</p></div>","PeriodicalId":39194,"journal":{"name":"Revista Espanola de Patologia","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2024-07-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141046939","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Primary hepatic pleomorphic liposarcoma: Case report and literature review 原发性肝脏多形性脂肪肉瘤：病例报告和文献综述

Revista Espanola de Patologia Pub Date : 2024-04-01 DOI: 10.1016/j.patol.2023.10.003

Ligia Redrobán , Jorge Lara-Endara , Nelson Montalvo , Christian Armijos , Javier Rodríguez-Suárez , Frans Serpa

引用次数: 0

Análisis de la carga laboral en tiempo médico en función del grado de complejidad de las muestras y propuesta de algoritmo para la distribución equitativa del trabajo asistencial en un servicio de anatomía patológica 根据样本的复杂程度分析医疗时间的工作量，并提出在解剖病理科公平分配护理工作的算法。

Revista Espanola de Patologia Pub Date : 2024-04-01 DOI: 10.1016/j.patol.2023.12.001

Angels Quera , Víctor Torres-Padrosa , Adrián Nieto Ortiz

{"title":"Análisis de la carga laboral en tiempo médico en función del grado de complejidad de las muestras y propuesta de algoritmo para la distribución equitativa del trabajo asistencial en un servicio de anatomía patológica","authors":"Angels Quera , Víctor Torres-Padrosa , Adrián Nieto Ortiz","doi":"10.1016/j.patol.2023.12.001","DOIUrl":"10.1016/j.patol.2023.12.001","url":null,"abstract":"<div><h3>Introduction</h3><p>In a pathological anatomy service, the workload in medical time is analyzed based on the complexity of the samples received and its distribution among pathologists is assessed, presenting a new computer algorithm that favors an equitable distribution.</p></div><div><h3>Methods</h3><p>Following the second edition of the Spanish guidelines for the estimation of workload in cytopathology and histopathology (medical time) according to the Spanish Pathology Society-International Academy of Pathology (SEAP-IAP) catalog of samples and procedures, we determined the workload units (UCL) per pathologist and the overall UCL of the service, the average workload of the service (MU factor), the time dedicated by each pathologist to healthcare activity and the optimal number of pathologists according to the workload of the service.</p></div><div><h3>Results</h3><p>We determined 12 197 total annual UCL for the chief pathologist, as well as 14 702 and 13 842 UCL for associate pathologists, with an overall of 40 742 UCL for the whole service. The calculated MU factor is 4.97. The chief pathologist devoted 72.25% of his working day to healthcare activity while associate pathologists dedicated 87.09% and 82.01% of their working hours. The optimal number of pathologists for the service is found to be 3.55.</p></div><div><h3>Conclusions</h3><p>The results demonstrate medical work overload and a non-equitable distribution of UCLs among pathologists. We propose a computer algorithm capable of distributing the workload in an equitable manner. It would be associated with the laboratory information system and take into account the type of specimen, its complexity and the dedication of each pathologist to healthcare activity.</p></div>","PeriodicalId":39194,"journal":{"name":"Revista Espanola de Patologia","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2024-04-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"139888896","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Esofagitis disecante superficial: dos casos de una misma entidad poco frecuente 表层剥离性食道炎：两例罕见病例

Revista Espanola de Patologia Pub Date : 2024-04-01 DOI: 10.1016/j.patol.2023.11.002

Leticia Ollero Domenche, María Elena del Valle Sánchez, Emilio Ignacio Abecia Martínez, Carlos Hörndler Argárate

引用次数: 0

Metastasizing pleomorphic adenoma of the parotid gland: A common tumour with a very unusual presentation 腮腺转移性多形性腺瘤：一种表现非常不寻常的常见肿瘤

Revista Espanola de Patologia Pub Date : 2024-04-01 DOI: 10.1016/j.patol.2023.10.002

Sherrin Jacob, Sana Ahuja, Sufian Zaheer, Mukul Singh

引用次数: 0

ChatGPT es un estudiante por encima de la media en la Facultad de Medicina de la Universidad de Zaragoza y un colaborador excelente en la elaboración de material docente ChatGPT 是萨拉戈萨大学医学院一名成绩优异的学生，也是教材编写的优秀合作者。

Revista Espanola de Patologia Pub Date : 2024-04-01 DOI: 10.1016/j.patol.2024.01.003

Clara Cabañuz , Mar García-García

{"title":"ChatGPT es un estudiante por encima de la media en la Facultad de Medicina de la Universidad de Zaragoza y un colaborador excelente en la elaboración de material docente","authors":"Clara Cabañuz , Mar García-García","doi":"10.1016/j.patol.2024.01.003","DOIUrl":"10.1016/j.patol.2024.01.003","url":null,"abstract":"<div><h3>Introduction and objective</h3><p>Artificial intelligence is fully present in our lives. In education, the possibilities of its use are endless, both for students and teachers.</p></div><div><h3>Material and methods</h3><p>The capacity of ChatGPT has been explored when solving multiple choice questions based on the exam of the subject «Anatomopathological Diagnostic and Therapeutic Procedures» of the first call of the 2022-23 academic year. In addition, to comparing their results with those of the rest of the students presented the probable causes of incorrect answers have been evaluated. Finally, its ability to formulate new test questions based on specific instructions has been evaluated.</p></div><div><h3>Results</h3><p>ChatGPT correctly answered 47 out of 68 questions, achieving a grade higher than the course average and median. Most failed questions present negative statements, using the words «no», «false» or «incorrect» in their statement. After interacting with it, the program can realize its mistake and change its initial response to the correct answer. Finally, ChatGPT can develop new questions based on a theoretical assumption or a specific clinical simulation.</p></div><div><h3>Conclusions</h3><p>As teachers we are obliged to explore the uses of artificial intelligence and try to use it to our benefit. Carrying out tasks that involve significant consumption, such as preparing multiple-choice questions for content evaluation, is a good example.</p></div>","PeriodicalId":39194,"journal":{"name":"Revista Espanola de Patologia","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2024-04-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"140270811","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Enteric duplication cysts in paediatric population along with literature review 儿科肠重复囊肿及文献综述

Revista Espanola de Patologia Pub Date : 2024-04-01 DOI: 10.1016/j.patol.2023.12.003

Sana Ahuja, Rashi Maheshwari, Saba Naaz, Sufian Zaheer

引用次数: 0

Diffuse coexpression of thyroid transcription factor-1 and p40 in a non-small cell carcinoma of the lung: Second case in the female population 非小细胞肺癌中甲状腺转录因子-1和p40的弥漫共表达：女性人群中的第二例

Revista Espanola de Patologia Pub Date : 2024-04-01 DOI: 10.1016/j.patol.2023.09.003

Marta Segado Martínez, Gema Ruiz García

引用次数: 0