Revista Espanola de Patologia最新文献_第10页

Tumores de colisión en la piel: un hallazgo incidental en la mayoría de los casos. Estudio retrospectivo y revisión de la literatura 皮肤碰撞瘤：大多数病例中的偶然发现。回顾性研究和文献综述

Revista Espanola de Patologia Pub Date : 2024-01-01 DOI: 10.1016/j.patol.2023.11.004

Sonia García-Fuertes , Lucía Prieto-Torres , Mar García-García

引用次数: 0

A diagnostic algorithm for sinonasal papillary non-keratinizing squamous cell carcinoma with DEK::AFF2 fusion and mimickers 鼻窦乳头状非角化鳞状细胞癌与 DEK::AFF2 融合和模拟物的诊断算法

Revista Espanola de Patologia Pub Date : 2024-01-01 DOI: 10.1016/j.patol.2023.08.002

Juan B. Laforga , Bacem K. Othman

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Fe de errores sobre artículos publicados en la Revista Española de Patología 对发表在《西班牙病理学杂志》上的文章的更正

Revista Espanola de Patologia Pub Date : 2024-01-01 DOI: 10.1016/j.patol.2023.10.001

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Kikuchi–Fujimoto disease type lymph node reaction with increased plasmacytoid dendritic cells may appear as a side effect following COVID-19 vaccination: Report of a case and literature review 接种 COVID-19 疫苗后可能会出现副作用，即出现质体树突状细胞增多的菊池-藤本氏病类型淋巴结反应：病例报告和文献综述

Revista Espanola de Patologia Pub Date : 2024-01-01 DOI: 10.1016/j.patol.2023.01.002

Germán Moreno de Juan , Amaia Pérez Del Barrio , Eduardo Germán Herrera Romero , Mario González Ruiz , Santiago Montes Moreno

{"title":"Kikuchi–Fujimoto disease type lymph node reaction with increased plasmacytoid dendritic cells may appear as a side effect following COVID-19 vaccination: Report of a case and literature review","authors":"Germán Moreno de Juan , Amaia Pérez Del Barrio , Eduardo Germán Herrera Romero , Mario González Ruiz , Santiago Montes Moreno","doi":"10.1016/j.patol.2023.01.002","DOIUrl":"10.1016/j.patol.2023.01.002","url":null,"abstract":"<div><p>Subsequent to mass vaccination programs against COVID-19, diverse side effects have been described, both at the injection site, such as pain, redness and swelling, and systemic effects such as fatigue, headache, muscle or joint pain. On rare occasions, a lymphadenopathic syndrome may develop, raising the clinical suspicion of a lymphoproliferative disorder. We present the case of a 30-year-old woman who developed self-limiting left axillary lymphadenopathy following COVID-19 vaccination. To date, only seven similar cases with a complete clinicopathological description have been published, and fourteen cases have been notified to the European adverse events databases (Eudravigilance) in relationship with vaccination against COVID-19.</p><p>It is important to be aware of this potential complication when a lymphadenopathic syndrome develops following vaccination, to avoid unnecessary treatment.</p></div>","PeriodicalId":39194,"journal":{"name":"Revista Espanola de Patologia","volume":"57 1","pages":"Pages 42-47"},"PeriodicalIF":0.0,"publicationDate":"2024-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.sciencedirect.com/science/article/pii/S1699885523000065/pdfft?md5=51c850a7d3fd67d014a91968499c191c&pid=1-s2.0-S1699885523000065-main.pdf","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"77132909","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

¿Qué es la Patología Moderna? Notas para la formación de un residente de Anatomía Patológica contemporáneo 什么是现代病理学？现代解剖病理学住院医师培训笔记。

Revista Espanola de Patologia Pub Date : 2024-01-01 DOI: 10.1016/j.patol.2024.01.001

Jesús Machuca-Aguado , Manuel Salto-Tellez

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El enigma de la enfermedad de Enrique IV, rey de Castilla: ¿padeció síndrome de McCune-Albright/displasia fibrosa? 卡斯蒂利亚国王亨利四世疾病之谜：他患有麦考恩-奥尔布赖特综合征/纤维发育不良？

Revista Espanola de Patologia Pub Date : 2023-10-01 DOI: 10.1016/j.patol.2023.06.003

M. Teresa Tuñón Álvarez , Adolfo Ruiz Calleja , Guiomar Pérez de Nanclares

{"title":"El enigma de la enfermedad de Enrique IV, rey de Castilla: ¿padeció síndrome de McCune-Albright/displasia fibrosa?","authors":"M. Teresa Tuñón Álvarez , Adolfo Ruiz Calleja , Guiomar Pérez de Nanclares","doi":"10.1016/j.patol.2023.06.003","DOIUrl":"https://doi.org/10.1016/j.patol.2023.06.003","url":null,"abstract":"<div><h3>Background</h3><p>Henry IV King of Castile, last king of the Trastámara dynasty, was the brother of Isabella the Catholic. He is known as “the impotent”. Based on previous descriptions by historians and biographers, Gregorio Marañón in 1922 described him as “eunuchoid dysplastic with acromegalic reaction and clear schizoid features”.</p></div><div><h3>Methods</h3><p>In 1946, a post-mortem inspection was carried out on the mummified corpse found in the Monastery of Guadalupe. A written document and some photographs were recorded. We have collected the signs and symptoms described and applied the international classification of diseases recommended by the World Health Organisation, ICD11-2023. We have relied on the coins issued in the money of Henry IV, on which we have identified enlargement of the thyroid gland.</p></div><div><h3>Results</h3><p>With the data available at this time, we suggest that Henry IV most probably suffered from: facial and polyostotic bone dysplasia, kyphosis, limb limping, multiple endocrine disorders, acromegaly with macrognatia, nodular thyroid disease, malodorous diaphoresis, erectile dysfunction, hypospadias, abnormal sexual development, “feminoid pelvis”, abdominal colic, oligodontia and dental displacement. It is possible that he also suffered from: precocious puberty, renal lithiasis with debilitating phosphaturia, carpal tunnel, thrombopenia and growth hormone-producing pituitary hyperplasia or adenoma.</p></div><div><h3>Conclusion</h3><p>We suggest that Henry IV may have suffered from McCune–Albrigth syndrome associated with fibrous dysplasia, a rare disease due to gain-of-function mutations in the <em>GNAS</em> gene.</p></div>","PeriodicalId":39194,"journal":{"name":"Revista Espanola de Patologia","volume":"56 4","pages":"Pages 243-251"},"PeriodicalIF":0.0,"publicationDate":"2023-10-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"67739319","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

JUNTOS, FORMAMOS UN GRAN EQUIPO, LA SEAP!! 我们一起组成了一个伟大的团队，La Seap！！

Revista Espanola de Patologia Pub Date : 2023-10-01 DOI: 10.1016/j.patol.2023.09.001

Dr. Santiago Ramón, Cajal Agüeras

引用次数: 0

Estudio de variantes genéticas en 169 pacientes de cáncer de pulmón no microcítico 169例非小细胞肺癌患者的遗传变异研究

Revista Espanola de Patologia Pub Date : 2023-10-01 DOI: 10.1016/j.patol.2023.06.002

Lydia Formanti Alonso , Lidia Atienza Cuevas , Raquel Romero García , Javier Mohigefer Barrera , Juan Jesús del Río Ignacio , Antonio Santisteban Espejo , Irene Bernal Florindo , Inmaculada Catalina Fernández , Marcial García Rojo

{"title":"Estudio de variantes genéticas en 169 pacientes de cáncer de pulmón no microcítico","authors":"Lydia Formanti Alonso , Lidia Atienza Cuevas , Raquel Romero García , Javier Mohigefer Barrera , Juan Jesús del Río Ignacio , Antonio Santisteban Espejo , Irene Bernal Florindo , Inmaculada Catalina Fernández , Marcial García Rojo","doi":"10.1016/j.patol.2023.06.002","DOIUrl":"10.1016/j.patol.2023.06.002","url":null,"abstract":"<div><h3>Introduction</h3><p>Lung cancer is the leading cause of cancer death in our country. Non-small cell lung cancer (NSCLC) represents the paradigm of personalized medicine. The main objective of this study is analysing the distribution of the most frequently described clinically significant variants in NSCLC, in our environment.</p></div><div><h3>Material and methods</h3><p>We studied the immunohistochemical expression of TTF1, p40 and PD-L1 and the genetic variants frequency using Next-Generation Sequencing (NGS) with a panel of 52 genes, in 174 NSCLC paraffin-embedded samples in 169 patients (111 men and 52 women) from the province of Cádiz.</p></div><div><h3>Results</h3><p>The immunohistochemical expression of TTF1, p40 and PD-L1 was positive in 87%, 0% and 46% in adenocarcinoma, and 0%, 100% and 41% in squamous cell carcinoma. In NGS, the most common single nucleotide variants (SNVs) were KRAS (36%), EGFR (14%), BRAF (10%), PIK3CA (8%), and MET (3%). The most frequent copy number variants (CNVs) were amplifications in NF1 (30%), EGFR (18%), CCND1 (9%), MYC (9%) and KRAS (7%). In women, SNV in EGFR are more frequent than in men (<em>P</em>  =.007361) or in EGFR (<em>P</em>  <!-->.0001). Gene fusions were detected in 16 patients (9.47%), in 9 cases in the MET gene.</p></div><div><h3>Conclusions</h3><p>We detected associations, not described so far, between immunohistochemical expression and specific gene variants, which could have an impact on the treatment of NSCLC patients.</p></div>","PeriodicalId":39194,"journal":{"name":"Revista Espanola de Patologia","volume":"56 4","pages":"Pages 233-242"},"PeriodicalIF":0.0,"publicationDate":"2023-10-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"47649897","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

The value of SOX10 expression in predicting perineural invasion in gastric cancer SOX10表达在预测胃癌神经周围浸润中的价值

Revista Espanola de Patologia Pub Date : 2023-10-01 DOI: 10.1016/j.patol.2023.05.003

Seyed Amir Miratashi Yazdi , Atieh Moghtadaie , Elham Nazar

{"title":"The value of SOX10 expression in predicting perineural invasion in gastric cancer","authors":"Seyed Amir Miratashi Yazdi , Atieh Moghtadaie , Elham Nazar","doi":"10.1016/j.patol.2023.05.003","DOIUrl":"10.1016/j.patol.2023.05.003","url":null,"abstract":"<div><h3>Background</h3><p>SRY-related HMG-box 10 (SOX10) protein has a confirmed role in the regulation of neural cell proliferation and differentiation. It is now suggested that the changes in SOX10 expression may be linked to neural invasion by cancer cells. We aimed to assess the value of SOX10 expression in predicting perineural invasion in gastric cancer.</p></div><div><h3>Methods</h3><p>A cross-sectional study was performed on 40 patients with gastric cancer. To assess perineural invasion, Hematoxylin & Eosin stained slides were examined. The expression of SOX10 was also examined by immunohistochemistry.</p></div><div><h3>Results</h3><p>Our study showed higher perineural invasion in those with SOX10 positivity as compared to those without SOX10 expression (64.0% vs. 6.7%, <em>p</em>  <!-->0.001). No association was revealed between other baseline variables and SOX10 positivity. The expression of this marker increased the chance of neural invasion up to 17 times as indicated by the multivariable regression modeling. Multivariable regression modeling indicated that the chance of neural invasion increased up to 17 times in cases of SOX10 positivity.</p></div><div><h3>Conclusion</h3><p>Overexpression of SOX10 is closely associated with the risk of perineural invasion in gastric cancer.</p></div>","PeriodicalId":39194,"journal":{"name":"Revista Espanola de Patologia","volume":"56 4","pages":"Pages 227-232"},"PeriodicalIF":0.0,"publicationDate":"2023-10-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"48714434","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

An incidental traditional serrated adenoma of the gallbladder: A case report 胆囊偶发传统锯齿状腺瘤1例

Revista Espanola de Patologia Pub Date : 2023-10-01 DOI: 10.1016/j.patol.2022.12.002

Emilio I. Abecia Martínez, Guillermo Ríos Ballestín, Jennifer Castillo Malla, Neus Martínez Arnau, Carlos Hörndler Argarate

引用次数: 0