原发性肝脏多形性脂肪肉瘤:病例报告和文献综述

Q4 Medicine
Ligia Redrobán , Jorge Lara-Endara , Nelson Montalvo , Christian Armijos , Javier Rodríguez-Suárez , Frans Serpa
{"title":"原发性肝脏多形性脂肪肉瘤:病例报告和文献综述","authors":"Ligia Redrobán ,&nbsp;Jorge Lara-Endara ,&nbsp;Nelson Montalvo ,&nbsp;Christian Armijos ,&nbsp;Javier Rodríguez-Suárez ,&nbsp;Frans Serpa","doi":"10.1016/j.patol.2023.10.003","DOIUrl":null,"url":null,"abstract":"<div><p>Primary hepatic liposarcoma is an extremely rare malignant tumour derived from adipocytes and is part of the group of mesenchymal tumours. We present the case of a 43-year-old Hispanic male patient with a pleomorphic hepatic liposarcoma and absence of MDM2 gene amplification. Two years and six months after surgery, the patient is asymptomatic. The present case is the first report of this entity with positive immunohistochemical testing for p16, p53, S100, vimentin and absence of MDM2 gene amplification.</p></div>","PeriodicalId":39194,"journal":{"name":"Revista Espanola de Patologia","volume":null,"pages":null},"PeriodicalIF":0.0000,"publicationDate":"2024-04-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.sciencedirect.com/science/article/pii/S1699885523000703/pdfft?md5=125776b3886ce590a6c432e80c3c7e77&pid=1-s2.0-S1699885523000703-main.pdf","citationCount":"0","resultStr":"{\"title\":\"Primary hepatic pleomorphic liposarcoma: Case report and literature review\",\"authors\":\"Ligia Redrobán ,&nbsp;Jorge Lara-Endara ,&nbsp;Nelson Montalvo ,&nbsp;Christian Armijos ,&nbsp;Javier Rodríguez-Suárez ,&nbsp;Frans Serpa\",\"doi\":\"10.1016/j.patol.2023.10.003\",\"DOIUrl\":null,\"url\":null,\"abstract\":\"<div><p>Primary hepatic liposarcoma is an extremely rare malignant tumour derived from adipocytes and is part of the group of mesenchymal tumours. We present the case of a 43-year-old Hispanic male patient with a pleomorphic hepatic liposarcoma and absence of MDM2 gene amplification. Two years and six months after surgery, the patient is asymptomatic. The present case is the first report of this entity with positive immunohistochemical testing for p16, p53, S100, vimentin and absence of MDM2 gene amplification.</p></div>\",\"PeriodicalId\":39194,\"journal\":{\"name\":\"Revista Espanola de Patologia\",\"volume\":null,\"pages\":null},\"PeriodicalIF\":0.0000,\"publicationDate\":\"2024-04-01\",\"publicationTypes\":\"Journal Article\",\"fieldsOfStudy\":null,\"isOpenAccess\":false,\"openAccessPdf\":\"https://www.sciencedirect.com/science/article/pii/S1699885523000703/pdfft?md5=125776b3886ce590a6c432e80c3c7e77&pid=1-s2.0-S1699885523000703-main.pdf\",\"citationCount\":\"0\",\"resultStr\":null,\"platform\":\"Semanticscholar\",\"paperid\":null,\"PeriodicalName\":\"Revista Espanola de Patologia\",\"FirstCategoryId\":\"1085\",\"ListUrlMain\":\"https://www.sciencedirect.com/science/article/pii/S1699885523000703\",\"RegionNum\":0,\"RegionCategory\":null,\"ArticlePicture\":[],\"TitleCN\":null,\"AbstractTextCN\":null,\"PMCID\":null,\"EPubDate\":\"\",\"PubModel\":\"\",\"JCR\":\"Q4\",\"JCRName\":\"Medicine\",\"Score\":null,\"Total\":0}","platform":"Semanticscholar","paperid":null,"PeriodicalName":"Revista Espanola de Patologia","FirstCategoryId":"1085","ListUrlMain":"https://www.sciencedirect.com/science/article/pii/S1699885523000703","RegionNum":0,"RegionCategory":null,"ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"","PubModel":"","JCR":"Q4","JCRName":"Medicine","Score":null,"Total":0}
引用次数: 0

摘要

原发性肝脂肪肉瘤是一种极其罕见的源自脂肪细胞的恶性肿瘤,属于间充质肿瘤。我们介绍了一例 43 岁的西班牙裔男性患者,他患有多形性肝脂肪肉瘤,且没有 MDM2 基因扩增。术后两年零六个月,患者无任何症状。本病例是首例免疫组化检测 p16、p53、S100、波形蛋白阳性且无 MDM2 基因扩增的此类肿瘤。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
Primary hepatic pleomorphic liposarcoma: Case report and literature review

Primary hepatic liposarcoma is an extremely rare malignant tumour derived from adipocytes and is part of the group of mesenchymal tumours. We present the case of a 43-year-old Hispanic male patient with a pleomorphic hepatic liposarcoma and absence of MDM2 gene amplification. Two years and six months after surgery, the patient is asymptomatic. The present case is the first report of this entity with positive immunohistochemical testing for p16, p53, S100, vimentin and absence of MDM2 gene amplification.

求助全文
通过发布文献求助,成功后即可免费获取论文全文。 去求助
来源期刊
Revista Espanola de Patologia
Revista Espanola de Patologia Medicine-Pathology and Forensic Medicine
CiteScore
0.90
自引率
0.00%
发文量
53
审稿时长
34 days
×
引用
GB/T 7714-2015
复制
MLA
复制
APA
复制
导出至
BibTeX EndNote RefMan NoteFirst NoteExpress
×
提示
您的信息不完整,为了账户安全,请先补充。
现在去补充
×
提示
您因"违规操作"
具体请查看互助需知
我知道了
×
提示
确定
请完成安全验证×
copy
已复制链接
快去分享给好友吧!
我知道了
右上角分享
点击右上角分享
0
联系我们:info@booksci.cn Book学术提供免费学术资源搜索服务,方便国内外学者检索中英文文献。致力于提供最便捷和优质的服务体验。 Copyright © 2023 布克学术 All rights reserved.
京ICP备2023020795号-1
ghs 京公网安备 11010802042870号
Book学术文献互助
Book学术文献互助群
群 号:481959085
Book学术官方微信