P A Maguire, T Bastiampillai, S Allison, F Wilkes, J C L Looi
{"title":"Rivastigmine for treatment-refractory posttraumatic stress disorder: a systematic review.","authors":"P A Maguire, T Bastiampillai, S Allison, F Wilkes, J C L Looi","doi":"10.12809/eaap2353","DOIUrl":"10.12809/eaap2353","url":null,"abstract":"<p><p>We conducted a systematic review evaluating the efficacy of rivastigmine augmentation for treatment-refractory posttraumatic stress disorder (PTSD). The Preferred Reporting Items for Systematic Reviews and Meta-Analyses guidelines were followed. The databases Ovid MEDLINE, PubMed, CINAHL, and EMBASE were searched using key words: 'rivastigmine' OR 'Exelon' OR 'rivastigmine augmentation' OR 'Exelon augmentation' AND 'posttraumatic stress disorder*' OR 'post-traumatic stress disorder*' OR 'PTSD' OR 'combat disorder*' OR 'post-traumatic symptoms'. The asterisk specified plural forms of the relevant word. Four papers were identified, comprising one double-blind randomised controlled trial, one non-controlled open trial, one case series (presenting three case studies), and one paper with two case studies. The randomised controlled trial found no statistically significant difference in efficacy, using the PTSD CheckList-Military Version as the relevant outcomes measure, between the active add-on rivastigmine interventions and placebo or treatment as usual. The open trial, although reporting relatively positive outcomes, had a weak study design and lacked reporting of key information, including participant sex and age and pre-rivastigmine PTSD measures. The assessment of efficacy was based on participants' reporting of subjective benefits, and clinician-rating using a Clinical Global Impression, rather than established PTSD assessments scales. Although the five case studies reported improvement in PTSD symptoms, there were confounding factors and limitations in clinical and demographic data, warranting caution regarding attributed benefits. There is a lack of methodologically robust evidence supporting the efficacy of add-on rivastigmine for the treatment of refractory PTSD. Additional research may help in further evaluating its possible clinical efficacy.</p>","PeriodicalId":39171,"journal":{"name":"East Asian Archives of Psychiatry","volume":"34 2","pages":"29-36"},"PeriodicalIF":0.0,"publicationDate":"2024-06-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141493851","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Developing the Youth Mental Health Clinic in Hong Kong: refocus and revisit of clinical practice for youth in the new millennium.","authors":"K T Chan, C W Law, E Y H Chen","doi":"10.12809/eaap2412","DOIUrl":"https://doi.org/10.12809/eaap2412","url":null,"abstract":"","PeriodicalId":39171,"journal":{"name":"East Asian Archives of Psychiatry","volume":"34 2","pages":"37-42"},"PeriodicalIF":0.0,"publicationDate":"2024-06-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141493847","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Normal pressure hydrocephalus disguising psychosis: a case report.","authors":"P M Manoj, M R Alam","doi":"10.12809/eaap2357","DOIUrl":"https://doi.org/10.12809/eaap2357","url":null,"abstract":"","PeriodicalId":39171,"journal":{"name":"East Asian Archives of Psychiatry","volume":"34 2","pages":"45-47"},"PeriodicalIF":0.0,"publicationDate":"2024-06-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141493849","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Ivabradine-induced delirium in a patient taking clozapine for treatment-resistant schizophrenia: a case report","authors":"S. Nath, S. Padhy, S. Kumari","doi":"10.12809/eaap2338","DOIUrl":"https://doi.org/10.12809/eaap2338","url":null,"abstract":"","PeriodicalId":39171,"journal":{"name":"East Asian Archives of Psychiatry","volume":"2019 40","pages":""},"PeriodicalIF":0.0,"publicationDate":"2024-03-13","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"140246088","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Prazosin for trauma-related nightmares in civilians at a Singapore hospital: a case series","authors":"Keng Chuan Soh, Yi Hang Tay","doi":"10.12809/eaap2344","DOIUrl":"https://doi.org/10.12809/eaap2344","url":null,"abstract":"","PeriodicalId":39171,"journal":{"name":"East Asian Archives of Psychiatry","volume":"14 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2024-03-13","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"140245753","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Prevalence of depressive and anxiety symptoms and perceived stress in hospitalised patients with COVID-19","authors":"Velayudhan Rajmohan, NM Aparna","doi":"10.12809/eaap2346","DOIUrl":"https://doi.org/10.12809/eaap2346","url":null,"abstract":"","PeriodicalId":39171,"journal":{"name":"East Asian Archives of Psychiatry","volume":"175 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2024-03-13","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"140246213","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Jalal Doufik, Laila Lahlou, Mustafa al’Absi, Jamaleddine Benhamida, Hicham Laaraj, Mina Ouhamou, Omar El oumary, Zineb Salehddine, Khalid Mouhadi, Ismail Rammouz
{"title":"Patients with schizophrenia in Morocco during the COVID-19 pandemic: a longitudinal observational study","authors":"Jalal Doufik, Laila Lahlou, Mustafa al’Absi, Jamaleddine Benhamida, Hicham Laaraj, Mina Ouhamou, Omar El oumary, Zineb Salehddine, Khalid Mouhadi, Ismail Rammouz","doi":"10.12809/eaap2255","DOIUrl":"https://doi.org/10.12809/eaap2255","url":null,"abstract":"","PeriodicalId":39171,"journal":{"name":"East Asian Archives of Psychiatry","volume":"15 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2024-03-13","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"140245956","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Parental Psychological Model for Children With Asthma and Its Mediating Role for Child Anxiety.","authors":"M Parvane, F Rezaei","doi":"10.12809/eaap2336","DOIUrl":"https://doi.org/10.12809/eaap2336","url":null,"abstract":"<p><strong>Background: </strong>Asthma is a common respiratory disease in children. Family factors play a role in its incidence and severity. This study investigated the effect of parental psychological flexibility, parental psychological adjustment to the child's illness, and parental psychological distress on the severity of asthma symptoms of children through mediating child anxiety.</p><p><strong>Methods: </strong>A total of 216 parents of children with asthma were asked to complete the Acceptance and Action Questionnaire, the Parent Experience of Child Illness, the Depression, Anxiety and Stress Scale - 21 Items, and the parent-report Spence Children's Anxiety Scale. Severity of asthma symptoms was assessed by spirometry.</p><p><strong>Results: </strong>The highest path coefficient was between parental psychological flexibility and the severity of paediatric asthma symptoms (β = 0.34). Parental psychological distress was found to affect the severity of asthma symptoms of children (β = -0.21) and also mediate child anxiety and then affect the severity of asthma symptoms of children (β = -0.25).</p><p><strong>Conclusion: </strong>Parental psychological flexibility, parental psychological adjustment to the child's illness, and parental psychological distress had significant effects on the severity of asthma symptoms of children through mediating child anxiety.</p>","PeriodicalId":39171,"journal":{"name":"East Asian Archives of Psychiatry","volume":"33 4","pages":"107-113"},"PeriodicalIF":0.0,"publicationDate":"2023-12-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141493845","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Resolution of Auditory Hallucinations After Right Temporal Haemorrhagic Stroke in a Patient With Clozapine-Resistant Schizoaffective Disorder: a Case Report.","authors":"Y Y C Tsang, N Y Hui, S K W Chan","doi":"10.12809/eaap2340","DOIUrl":"https://doi.org/10.12809/eaap2340","url":null,"abstract":"<p><p>We present a young woman with clozapine-resistant schizoaffective disorder who was treated with maintenance electroconvulsive therapy and multiple antipsychotics but continued to have auditory hallucinations. She had a haemorrhagic stroke secondary to a ruptured arteriovenous malformation at the right superior temporal gyrus, which was excised during emergency craniotomy. Despite having neurological deficits after the stroke, she reported cessation of auditory hallucinations. Magnetic resonance imaging of the brain showed Wallerian degeneration over the right temporal region. Personalised neuromodulation intervention may be a more effective treatment option for clozapine-resistant schizophrenia.</p>","PeriodicalId":39171,"journal":{"name":"East Asian Archives of Psychiatry","volume":"33 4","pages":"126-130"},"PeriodicalIF":0.0,"publicationDate":"2023-12-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141493846","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
K Kawai, H Yamada, H Tomioka, A Iwanami, A Inamoto
{"title":"Factors Associated With Physical Restraints in a Psychiatric Unit in Japan: a Retrospective Study.","authors":"K Kawai, H Yamada, H Tomioka, A Iwanami, A Inamoto","doi":"10.12809/eaap2334","DOIUrl":"https://doi.org/10.12809/eaap2334","url":null,"abstract":"<p><strong>Objective: </strong>To identify factors associated with the use and duration of physical restraint (PR) in a psychiatric unit in Japan.</p><p><strong>Methods: </strong>Medical records of 1308 patients admitted first time to the psychiatric emergency unit of Showa University Northern Yokohama Hospital between 1 January 2014 and 31 December 2021 were retrospectively reviewed. Data collected included patient age, sex, outpatient treatment, living arrangements, disability pension status, diagnosis (based on ICD-10), and psychotropic medication use at admission (chlorpromazine equivalent dose, imipramine equivalent dose, diazepam equivalent dose, and number of mood stabilisers administered). Logistic regression analysis and multiple regression analysis were used to identify factors associated with the use and duration of PR, respectively.</p><p><strong>Results: </strong>Of 1308 patients, 399 (30.5%) were subjected to PR and 909 (69.5%) were not. Among the 399 patients subjected to PR, 54 were excluded from the multiple regression analysis for duration of PR as they remained subject to PR on the day of discharge. The remaining 345 patients were subject to PR for a median of 10 days. PR utilisation was associated with male sex (odds ratio [OR] = 1.420), treatment at our hospital (OR = 0.260), treatment at other hospitals (OR = 0.645), F3 diagnosis (depression) [OR = 0.290], F4-9 diagnosis (OR = 0.309), and imipramine equivalent dose at admission (unit OR = 0.994). The log-transformed duration of PR was independently associated with the age group of 50 to 69 years (β = 0.248), the age group of ≥70 years (β = 0.274), receiving a disability pension (β = 0.153), an F1 diagnosis (β = -0.187), an F4-9 diagnosis (β = -0.182), chlorpromazine equivalent dose at admission (β = 0.0004), and number of mood stabilisers administered at admission (β = -0.270).</p><p><strong>Conclusion: </strong>Identifying factors associated with the use and duration of PR may lead to reduction in the use and duration of PR.</p>","PeriodicalId":39171,"journal":{"name":"East Asian Archives of Psychiatry","volume":"33 4","pages":"120-125"},"PeriodicalIF":0.0,"publicationDate":"2023-12-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141493788","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}