Open Respiratory Medicine Journal最新文献

{"title":"Female Sexual Dysfunction Among a Sample of Egyptian Patients with Asthma.","authors":"Mona Reda,&nbsp;Dina Ruby","doi":"10.2174/1874306402014010038","DOIUrl":"https://doi.org/10.2174/1874306402014010038","url":null,"abstract":"<p><strong>Background: </strong>Despite asthma being a worldwide disease, still little awareness regarding the sexual function of asthmatic patients exists. So this study attempts to assess the Female Sexual Dysfunction (FSD) amongst Egyptian females with asthma and its burden on their quality of life.</p><p><strong>Materials & methods: </strong>The sample consisted of 180 subjects, comprising 90 asthma patients and 90 healthy controls aged between 20 - 45 years old, who visited the Chest Department Outpatient Clinic of Ain Shams University Hospital between January and December 2018. We reported all the subjects' demographic and clinical data; both groups answered an Arabic version of the Female Sexual Function Index (Ar FSFI) and World Health Organization Quality of Life Questionnaire abbreviated version (WHOQL-Bref).</p><p><strong>Results: </strong>90% of asthmatic females had FSD; total Female Sexual Function Index score was 12.956 ± 10.3 in asthmatic females compared to 25.423 ± 5.521 in healthy controls; 45.6% of asthmatic females with sexual dysfunction had moderate asthma and 86.4% had uncontrolled asthma, 40.1% of them had a low educational level and 80.2% were unemployed.</p><p><strong>Conclusion: </strong>Jobless females with severe uncontrolled asthma and a low educational level had higher sexual dysfunction and a poor quality of life.</p>","PeriodicalId":39127,"journal":{"name":"Open Respiratory Medicine Journal","volume":"14 ","pages":"38-44"},"PeriodicalIF":0.0,"publicationDate":"2020-10-23","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7705956/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"38694600","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Effects of Nintedanib on Quantitative Lung Fibrosis Score in Idiopathic Pulmonary Fibrosis.","authors":"Lisa Lancaster,&nbsp;Jonathan Goldin,&nbsp;Matthias Trampisch,&nbsp;Grace Hyun Kim,&nbsp;Jonathan Ilowite,&nbsp;Lawrence Homik,&nbsp;David L Hotchkin,&nbsp;Mitchell Kaye,&nbsp;Christopher J Ryerson,&nbsp;Nesrin Mogulkoc,&nbsp;Craig S Conoscenti","doi":"10.2174/1874306402014010022","DOIUrl":"https://doi.org/10.2174/1874306402014010022","url":null,"abstract":"<p><strong>Background: </strong>Nintedanib slows disease progression in patients with Idiopathic Pulmonary Fibrosis (IPF) by reducing decline in Forced Vital Capacity (FVC). The effects of nintedanib on abnormalities on high-resolution computed tomography scans have not been previously studied.</p><p><strong>Objective: </strong>We conducted a Phase IIIb trial to assess the effects of nintedanib on changes in Quantitative Lung Fibrosis (QLF) score and other measures of disease progression in patients with IPF.</p><p><strong>Methods: </strong>113 patients were randomized 1:1 to receive nintedanib 150 mg bid or placebo double-blind for ≥6 months, followed by open-label nintedanib. The primary endpoint was the relative change from baseline in QLF score (%) at month 6. Analyses were descriptive and exploratory.</p><p><strong>Results: </strong>Adjusted mean relative changes from baseline in QLF score at month 6 were 11.4% in the nintedanib group (n=42) and 14.6% in the placebo group (n=45) (difference 3.2% [95% CI: -9.2, 15.6]). Adjusted mean absolute changes from baseline in QLF score at month 6 were 0.98% and 1.33% in these groups, respectively (difference 0.35% [95% CI: -1.27, 1.96]). Adjusted mean absolute changes from baseline in FVC at month 6 were -14.2 mL and -83.2 mL in the nintedanib (n=54) and placebo (n=54) groups, respectively (difference 69.0 mL [95% CI: -8.7, 146.8]).</p><p><strong>Conclusion: </strong>Exploratory data suggest that in patients with IPF, 6 months' treatment with nintedanib was associated with a numerically smaller degree of fibrotic change in the lungs and reduced FVC decline versus placebo. These data support previous findings that nintedanib slows the progression of IPF.</p>","PeriodicalId":39127,"journal":{"name":"Open Respiratory Medicine Journal","volume":"14 ","pages":"22-31"},"PeriodicalIF":0.0,"publicationDate":"2020-09-22","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7539538/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"38518855","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Evaluation of Prognostic Factors Associated with Postoperative Complications Following Pulmonary Hydatid Cyst Surgery.","authors":"Mojtaba Ahmadinejad,&nbsp;Mozaffar Hashemi,&nbsp;Nasim Azizallahi","doi":"10.2174/1874306402014010016","DOIUrl":"https://doi.org/10.2174/1874306402014010016","url":null,"abstract":"<p><strong>Background: </strong>Hydatid cysts are one of the serious complications following echinococcus infection. The liver and the lungs are the most affected organs, respectively. The severity of the disease is associated with the increase in the number and the size of the cysts, cysts rupture, and systemic effects. The aim of this study is to evaluate prognostic factors that are associated with the increased incidence of postoperative complications following pulmonary hydatid cyst surgery.</p><p><strong>Methods: </strong>Patients referred to Madani hospital from 2014-2018, presenting pulmonary hydatid cysts were included in this study. All the patients were evaluated based on the following parameters: age, gender, location and size of the cysts, rupture status of the cysts (intact or perforated), type of surgical intervention (capitonnage or segmentectomy) and Erythrocyte Sedimentation Rate (ESR). The factors were then compared with postoperative complications. Statistical analysis of the data obtained was conducted using R-software.</p><p><strong>Results: </strong>Of 76 patients enrolled in our study, 52.63% were males and 47.36% were female. Air leak complication was reported in 13.15% of the patients and 3.94% of the patients were presented with pleural effusion. Postoperative complications were significantly associated with the perforated (ruptured) cysts p= 0.001, segmentectomy p= 0.013, giant hydatid cysts p= 0.007 and ESR p= 0.014. However, the side of the lung was not significantly related to postoperative complications.</p><p><strong>Conclusion: </strong>Our study reports that perforated cysts, increased size, segmentectomy and abnormal ESR are likely to increase postoperative complications following pulmonary hydatid cysts surgery. Prospective studies with perioperative parameters and greater sample size can help to deduce better inferences.</p>","PeriodicalId":39127,"journal":{"name":"Open Respiratory Medicine Journal","volume":"14 ","pages":"16-21"},"PeriodicalIF":0.0,"publicationDate":"2020-07-21","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7372731/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"38220206","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"The True Challenges of the Covid-19 Epidemics: The Need for Essential Levels of Care for All.","authors":"Mauro Giovanni Carta,&nbsp;Ferdinando Romano,&nbsp;Germano Orrù","doi":"10.2174/1874306402014010008","DOIUrl":"https://doi.org/10.2174/1874306402014010008","url":null,"abstract":"In the last decades, biomedical research and funding supporting it have given a relevant impulse to developing socalled “Personalized Medicine” (PM) and “precision medicine” (the latter definition with emphasis on the usefulness of dividing patients into target groups). This perspective has increased knowledge on how we can predict disease susceptibility and prognosis in a person or how we can define a tailor-made treatment on specific individual immune-genomic characteristics and disease and thus improve the health of such a person [1].","PeriodicalId":39127,"journal":{"name":"Open Respiratory Medicine Journal","volume":"14 ","pages":"8-9"},"PeriodicalIF":0.0,"publicationDate":"2020-03-16","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7254820/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"38022668","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Respiratory Symptoms and Diminished Lung Functions Associated with Occupational Dust Exposure Among Iron Ore Mine Workers in Iran.","authors":"Abdollah Gholami,&nbsp;Reza Tajik,&nbsp;Khaula Atif,&nbsp;Amin Allah Zarei,&nbsp;Sedigheh Abbaspour,&nbsp;Gholamheidar Teimori-Boghsani,&nbsp;Mohsen Attar","doi":"10.2174/1874306402014010001","DOIUrl":"https://doi.org/10.2174/1874306402014010001","url":null,"abstract":"<p><strong>Background: </strong>Dust exposure at quarry mines is inevitable and can result in poor air quality. This research aimed to assess pulmonary symptoms and lung functions of dust-exposed workers at an iron-ore mine in eastern Iran.</p><p><strong>Methods: </strong>An environmental cross-sectional study sampled 174 dust-exposed mine workers and 93 unexposed administrative employees as the reference group. A standardized questionnaire on respiratory symptoms was completed in accordance with recommendations of the American Thoracic Society(ATS). Calibrated spirometer measured Pulmonary Function Tests (PFTs). Data were analyzed <i>via</i> SPSS-21, integrating independent samples t-test, Chi-square and linear or logistic-regression models.</p><p><strong>Results: </strong>There was no significant variation between dust-exposed and reference groups in terms of age, weight, height, work experience and the number of smokers (<i>P</i>>0.05). Mean levels of exposure to inhalable and respirable mineral-dust were 15.09±2.34 and 3.45±2.57 mg/m³ respectively. Pulmonary capacities of dust-exposed group were considerably decreased as compared to others (Forced Vital Capacity [FVC] 86.55±13.77 <i>vs</i>. 105.05±21.5; Forced Expiratory Volume in 1 second [FEV1] 88.06±16.8 <i>vs</i>. 105.81±21.55; FEV1/FVC 103.03±18.17 <i>vs</i>. 93.3±12.49; and Peak Expiratory Flow [PEF] 89.82±22.58 <i>vs</i>. 98.09±20.60) (<i>P</i><0.001); with a higher prevalence of cough (<i>P</i>=0.041), wheezing (<i>P</i>=0.032), and dyspnea (<i>P</i>=0.035) among formers. Age along with exposure to respirable-dust significantly reduced FVC, FEV1 and FEV1/FVC. Cigarette consumption attenuated FVC and FEV1 on an average of 5 to 9 units.</p><p><strong>Conclusion: </strong>Controlled occupational dust-exposure is a definitive pre-requisite to reduce respiratory problems among quarry workers, with an explicit consideration towards mineral- mine workers. Modifiable accomplices like smoking and non-compliance of PPEs usage should be amicably resolved.</p>","PeriodicalId":39127,"journal":{"name":"Open Respiratory Medicine Journal","volume":"14 ","pages":"1-7"},"PeriodicalIF":0.0,"publicationDate":"2020-01-23","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7254822/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"38022667","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Revisiting the Role of Vitamin C in Sepsis. Is it a Forlorn Hope or is there Still Dearth of data?","authors":"Salim Surani,&nbsp;Munish Sharma","doi":"10.2174/1874306401913010055","DOIUrl":"https://doi.org/10.2174/1874306401913010055","url":null,"abstract":"This editorial intends to succinctly discuss the outcomes of a recent study by Fowler AA III et al. regarding the effects of intravenous (IV) vitamin C in patients with sepsis and Acute Respiratory Distress Syndrome (ARDS) [1]. Despite the advancement in diagnostic and therapeutic modalities, adoption of protocol-based management strategies and a better understanding of the pathophysiology of sepsis, the burden of mortality and morbidity from sepsis remains humongous [2 4]. In a relentless effort to add to the current repertoire of therapeutic options in sepsis, potential beneficial effects of Vitamin C have been tested in the study by Fowler AA III et al. [1]. The results of this study have garnered a huge deal of interest in the medical fraternity.","PeriodicalId":39127,"journal":{"name":"Open Respiratory Medicine Journal","volume":"13 ","pages":"55-57"},"PeriodicalIF":0.0,"publicationDate":"2019-12-31","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://ftp.ncbi.nlm.nih.gov/pub/pmc/oa_pdf/2a/55/TORMJ-13-55.PMC7040467.pdf","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"37739700","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Treatment Outcomes of Tuberculosis Retreatment Case and Its Determinants in West Ethiopia.","authors":"Mohammed Gebre Dedefo,&nbsp;Meti Teressa Sirata,&nbsp;Balisa Mosisa Ejeta,&nbsp;Getu Bayisa Wakjira,&nbsp;Ginenus Fekadu,&nbsp;Busha Gamachu Labata","doi":"10.2174/1874306401913010058","DOIUrl":"https://doi.org/10.2174/1874306401913010058","url":null,"abstract":"<p><strong>Background: </strong>Tuberculosis (TB) is a major public health concern in the developing world. World Health Organization's (WHO's) list of 30 high TB burden countries accounted for 87% of the world's cases. The annual infection rate in developing countries reached 2% or more; where as in developed countries this figure is 0.5%.</p><p><strong>Objective: </strong>The objective of this study is to assess treatment outcomes of tuberculosis retreatment case and its determinants at Nekemte Referral Hospital (NRH), West Ethiopia.</p><p><strong>Methods: </strong>A retrospective cross-sectional study was conducted. All registered adult TB patients under retreatment regimen who were treated at NRH TB clinics from January 2014 to December 2017 were included in this study. A multiple logistic regression was used to assess the significance and strength of association. A P-value <0.05 was used as statistically significant.</p><p><strong>Results: </strong>The prevalence of retreatment case was 12.12%. Of 219 study participants 159(72.6%) were patients with relapse, 43(19.6%) were with retreatment after failure and 17(7.8%) were patients who return after loss to follow-up. On multivariable logistic analysis poor treatment outcome was more likely to occur among patients with positive Acid Fast Bacilli (AFB) result at 5^th month (Adjusted odds ratio (AOR =4.3, 95%, (1.8-10.0) p=0.001) and patients taking category 1 (2ERHZ/4RH) drugs (AOR=2.1, 95% CI= (1.1-4.5) p=0.048).</p><p><strong>Conclusion: </strong>This study showed that treatment outcomes of TB retreatment case were below standard set by the WHO. Factors that were significantly associated with poor treatment outcome were positive AFB resulting at 5^th month and patients on category 1(2ERHZ/4RH).</p>","PeriodicalId":39127,"journal":{"name":"Open Respiratory Medicine Journal","volume":"13 ","pages":"58-64"},"PeriodicalIF":0.0,"publicationDate":"2019-12-31","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://ftp.ncbi.nlm.nih.gov/pub/pmc/oa_pdf/45/09/TORMJ-13-58.PMC7040470.pdf","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"37739702","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Is Obesity Hypoventilation Syndrome A Postmenopausal Disorder?","authors":"Ahmed S BaHammam,&nbsp;Aljohara S Almeneessier","doi":"10.2174/1874306401913010051","DOIUrl":"https://doi.org/10.2174/1874306401913010051","url":null,"abstract":"<p><p>Previous studies have assessed the role of gender and menopause in Obstructive Sleep Apnea (OSA). It is well known that menopause is a major risk factor for OSA. However, analogous studies on obesity Hypoventilation Syndrome (OHS) are limited. Recent studies have suggested that OHS is more prevalent in postmenopausal women. Moreover, women with OHS seem to have excess comorbidities, including hypothyroidism, hypertension, pulmonary hypertension, and diabetes mellitus, compared to men. In the present perspective, we discuss recent data on the prevalence and comorbidities associated with OHS in women, as well as the use of noninvasive ventilation in women with OHS, and try to answer the question, \"Is OHS a disorder of postmenopausal women?\"</p>","PeriodicalId":39127,"journal":{"name":"Open Respiratory Medicine Journal","volume":"13 ","pages":"51-54"},"PeriodicalIF":0.0,"publicationDate":"2019-11-15","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://ftp.ncbi.nlm.nih.gov/pub/pmc/oa_pdf/a1/9a/TORMJ-13-51.PMC6952852.pdf","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"37559374","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Is it Time to Replace Direct Laryngoscopy with Video Laryngoscopy in Airway Management in Training Facilities?","authors":"Salim Surani,&nbsp;Joseph Varon","doi":"10.2174/1874306401913010048","DOIUrl":"https://doi.org/10.2174/1874306401913010048","url":null,"abstract":"Endotracheal Intubation (EI) remains an essential procedure to protect the airway and maintain means for oxygenation and ventilation in acutely ill patients as well as those undergoing general anesthesia during surgical procedures [1 3]. Outside the operation room, it carries significant hazard, as it is fre-quently performed by inexperienced healthcare providers and often physicians-in-training [4 6]. In some institutions, midlevel providers and respiratory therapists also manage the airway in emergency circumstances. This has led to a significant risk of complications when airway management is performed outside the confines of the operating room.","PeriodicalId":39127,"journal":{"name":"Open Respiratory Medicine Journal","volume":"13 ","pages":"48-50"},"PeriodicalIF":0.0,"publicationDate":"2019-09-30","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://ftp.ncbi.nlm.nih.gov/pub/pmc/oa_pdf/5e/a5/TORMJ-13-48.PMC6918540.pdf","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"37518176","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Prevalence and Predictors of Ocular Complications in Obstructive Sleep Apnea Patients: A Cross-sectional Case-control Study.","authors":"Nesreen E Morsy,&nbsp;Badawi E Amani,&nbsp;Ahmad A Magda,&nbsp;Awadalla J Nabil,&nbsp;Seithikurippu R Pandi-Perumal,&nbsp;Ahmed S BaHammam,&nbsp;David Warren Spence,&nbsp;Per O Lundmark,&nbsp;Nevin Fw Zaki","doi":"10.2174/1874306401913010019","DOIUrl":"https://doi.org/10.2174/1874306401913010019","url":null,"abstract":"<p><strong>Purpose: </strong>This study sought to identify the magnitude and the possible risk factors of ocular complications in patients with Obstructive Sleep Apnea (OSA).</p><p><strong>Methods: </strong>A hospital-based cross-sectional study with a nested case-control design was conducted. Qualifying study subjects were patients who had been diagnosed with moderate to severe OSA (AHI index of ≥ 5, n=80), and control subjects (n=20) who had an AHI index of ≤ 5 (\"normal\"). Study participants were recruited from Mansoura University Hospital's Sleep Disorders Clinic in Mansoura, Egypt.Selected subjects were assessed for ocular complications at Mansoura Univerity Hospital Ophthalmic Center, (Mansoura), Egypt. An ophthalmic history was recorded, and opthalmic testing was carried out. The testing included unaided visual acuity measurement, refraction, best-corrected visual acuity measurement, slit lamp bio-microscopic evaluation of the anterior segment and anterior segment photography, dilated fundus examination, intraocular pressure measurement, fundus photo, and fluorescein angiography, and visual field assessment. Various tests of OSA symptoms were also monitored, including the AHI, lowest oxygen concentrations and desaturation index plus the overall severity index. .</p><p><strong>Results: </strong>It was found that OSA patients n=28 (35%), n=24 (30%), n=4 (5%) had senile cataract, normal tension glaucoma, and retinal ischemia, respectively, with an overall prevalence of 45%. Additionally, the OSA group had seven times greater risk (OR=7.36, 95%CI: 1.6-33.86) of vision-threatening disorders compared to the controls. OSA patients were observed to be at a greater risk of senile cataract 28 (35%), normal tension glaucoma 24 (30%), retinal ischemia 4 (5%) and conjunctival hyperemia and dry eye (OR=3.77, 95%CI: 1.02-13.95, OR=4.36, 95%CI: 1.26-17.08). Also, multivariate logistic regression analysis testing showed that the lowest oxygen saturation index was the only significant predictor negatively associated with vision-threatening disorders (OR=0.84, 95%CI: 0.75-0.93).</p><p><strong>Conclusion: </strong>The risk of vision-threatening and non-threatening ocular disorders is higher among OSA cases. The lowest oxygen saturation index was the only significant predictor of vision-threatening disorders. These findings support the recommendation that a full ophthalmic examination should be carried out on patients with confirmed OSA.</p>","PeriodicalId":39127,"journal":{"name":"Open Respiratory Medicine Journal","volume":"13 ","pages":"19-30"},"PeriodicalIF":0.0,"publicationDate":"2019-07-31","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://ftp.ncbi.nlm.nih.gov/pub/pmc/oa_pdf/5f/4a/TORMJ-13-19.PMC6918538.pdf","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"37518250","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}