Revisiting the Role of Vitamin C in Sepsis. Is it a Forlorn Hope or is there Still Dearth of data?

Abstract

This editorial intends to succinctly discuss the outcomes of a recent study by Fowler AA III et al. regarding the effects of intravenous (IV) vitamin C in patients with sepsis and Acute Respiratory Distress Syndrome (ARDS) [1]. Despite the advancement in diagnostic and therapeutic modalities, adoption of protocol-based management strategies and a better understanding of the pathophysiology of sepsis, the burden of mortality and morbidity from sepsis remains humongous [2 4]. In a relentless effort to add to the current repertoire of therapeutic options in sepsis, potential beneficial effects of Vitamin C have been tested in the study by Fowler AA III et al. [1]. The results of this study have garnered a huge deal of interest in the medical fraternity.