Braulio Martínez-Burbano, Joselyn Miño Zambrano, Francisco Caiza-Zambrano
{"title":"¿La prevalencia de aneurismas cerebrales cambia con la altitud geográfica? Estudio retrospectivo en Ecuador","authors":"Braulio Martínez-Burbano, Joselyn Miño Zambrano, Francisco Caiza-Zambrano","doi":"10.1016/j.neuarg.2023.04.001","DOIUrl":"10.1016/j.neuarg.2023.04.001","url":null,"abstract":"<div><h3>Introduction</h3><p>The prevalence of cerebral aneurysms varies between 2% and 4% in the general population. Studies suggest that living in high altitude regions (>2500<!--> <!-->m) reduces the risk of developing a stroke. However, the prevalence of cerebral aneurysms and the risk of their rupture in high-altitude populations have not yet been determined.</p></div><div><h3>Objective</h3><p>To estimate the prevalence of cerebral aneurysms in the population treated at neurology department of the Carlos Andrade Marín Hospital in Quito (city located at 2850<!--> <!-->m).</p></div><div><h3>Patients and methods</h3><p>Retrospective observational study, in patients older than 18 years with a diagnosis of cerebral aneurysm treated between January 1, 2010 and December 31, 2018, with ICD-10 codes I67.1 and I60.0. Demographic and imaging variables were analyzed.</p></div><div><h3>Results</h3><p>A total of 8390 patients were attended, of which 450 were diagnosed with cerebral aneurysm. The prevalence in the 9-year period was 5.3%, it was higher in women and in ages between 50 and 59 years. A single aneurysm was identified in 76.5% of cases, 4.3% were ruptured aneurysms and 1.04% were unruptured. Small aneurysms (<7<!--> <!-->mm) were the most frequent.</p></div><div><h3>Conclusion</h3><p>The prevalence and characteristics of cerebral aneurysms in patients treated in Quito, a high-altitude city, were similar to those reported in the literature. Further investigations are needed to determine the influence of high altitudes on the epidemiology of this disease.</p></div>","PeriodicalId":39051,"journal":{"name":"Neurologia Argentina","volume":"15 3","pages":"Pages 170-176"},"PeriodicalIF":0.0,"publicationDate":"2023-07-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"48988744","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Isabel Soto , Jorge Correa , María Florencia Villafañe Fioti , Fernando Messina , Gabriela Santiso , Marcelo Corti
{"title":"Meningoencefalitis por Histoplasma capsulatum. Una complicación infrecuente de la histoplasmosis diseminada","authors":"Isabel Soto , Jorge Correa , María Florencia Villafañe Fioti , Fernando Messina , Gabriela Santiso , Marcelo Corti","doi":"10.1016/j.neuarg.2023.03.002","DOIUrl":"10.1016/j.neuarg.2023.03.002","url":null,"abstract":"<div><p>Histoplasmosis is a common endemic in the Americas, that is caused by the dimorphic fungi, <em>Histoplasma capsulatum</em>. Pulmonary involvement is the most frequent clinical presentation of the disease, but disseminated acute or subacute infection, with skin and oral mucosal lesions, can happen in association with impaired cellular immunity, particulary human immunodeficiency virus (HIV) infection. Central nervous system infection occurs in only 5% to 10% of patients with disseminated histoplasmosis. The most common clinical form is a subacute or chronic basal meningitis. The diagnosis should be considered in all patients with chronic lymphocytic meningitis in endemic regions.</p></div>","PeriodicalId":39051,"journal":{"name":"Neurologia Argentina","volume":"15 3","pages":"Pages 226-230"},"PeriodicalIF":0.0,"publicationDate":"2023-07-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"46829030","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Astrid Torres Jaimes , Loida Camargo , Norman Lopez
{"title":"Meningioma de la convexidad en placa: reporte de caso y revisión de la literatura","authors":"Astrid Torres Jaimes , Loida Camargo , Norman Lopez","doi":"10.1016/j.neuarg.2022.07.001","DOIUrl":"10.1016/j.neuarg.2022.07.001","url":null,"abstract":"<div><p>Plaque meningioma is a rare subtype of tumor located primarily in the sphenoorbital region characterized by a hyperostotic and invasive architecture of the dura mater with unique diagnostic and treatment considerations. We present a case of plaque meningioma of the convexity in a 44-year-old patient with an adequate response to palliative surgical resection and adjuvant radiotherapy.</p></div>","PeriodicalId":39051,"journal":{"name":"Neurologia Argentina","volume":"15 3","pages":"Pages 203-205"},"PeriodicalIF":0.0,"publicationDate":"2023-07-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"42246027","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Síndrome de Cogan asociado a vasculitis sistémica con evolución tórpida","authors":"Lucia Varela , Pablo Sosa , Agustina Moroni , Facundo Silveira , Ariel Luzzi , Alejandra Heriz","doi":"10.1016/j.neuarg.2023.01.002","DOIUrl":"10.1016/j.neuarg.2023.01.002","url":null,"abstract":"<div><h3>Introduction</h3><p>Cogan's syndrome is a rare autoimmune disease characterized by ocular and auditory manifestations. The key symptoms are interstitial keratitis and sudden hearing loss. Many patients also present systemic compromise, vasculitis being a rare manifestation of the disease.</p></div><div><h3>Case report</h3><p>62-year-old female patient who consulted for transient brachial dysesthesias and after a complete evaluation the diagnosis of ischemic cerebrovascular accident (CVA) of undetermined cause was made. Later, she presented a new cerebrovascular event, for which she was studied again, without pathological findings. In the following two months, the presence of systemic symptoms (headache, weight loss), bilateral hearing loss, episodes of vertigo and a new stroke were added to the clinical picture. Due to suspicion of systemic vasculitis, positron emission tomography was performed with evidence of aortic and femoral vasculitis. The condition was interpreted as Cogan's syndrome and immunosuppressive treatment was started with daily oral meprednisone and monthly cyclophosphamide. Despite treatment, the patient evolved with a new extensive stroke associated with thrombosis of both carotid arteries. Plasmapheresis was performed, with no response since the patient died 4 months after the clinical picture began.</p></div><div><h3>Conclusion</h3><p>The presentation of systemic manifestations of Cogan's syndrome prior to visual and auditory involvement represent a rare onset of the disease. Likewise, stroke as an initial manifestation is extremely rare, so it should be suspected in cases of repetitive events in patients with no other apparent causes.</p></div>","PeriodicalId":39051,"journal":{"name":"Neurologia Argentina","volume":"15 3","pages":"Pages 221-225"},"PeriodicalIF":0.0,"publicationDate":"2023-07-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"42841272","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Jessica Cuesta Bernal , Paula Martínez Micolta , Luz Helena Castaño Torres , Mónica Alexandra Zúñiga-Núñez , Juliana Vargas Osorio
{"title":"Fe de errores de «Efectos de la dieta cetogénica en pacientes adultos con epilepsia refractaria» [Neurol Arg. 2021;13(4):221-227]","authors":"Jessica Cuesta Bernal , Paula Martínez Micolta , Luz Helena Castaño Torres , Mónica Alexandra Zúñiga-Núñez , Juliana Vargas Osorio","doi":"10.1016/j.neuarg.2023.07.005","DOIUrl":"https://doi.org/10.1016/j.neuarg.2023.07.005","url":null,"abstract":"","PeriodicalId":39051,"journal":{"name":"Neurologia Argentina","volume":"15 3","pages":"Page 251"},"PeriodicalIF":0.0,"publicationDate":"2023-07-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"49901906","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Estudio neurosonológico en el ictus isquémico agudo por disección carotídea: a propósito de un caso","authors":"Iago García Díaz , Esperanza Ortegón Aguilar","doi":"10.1016/j.neuarg.2023.07.003","DOIUrl":"10.1016/j.neuarg.2023.07.003","url":null,"abstract":"","PeriodicalId":39051,"journal":{"name":"Neurologia Argentina","volume":"15 3","pages":"Pages 252-253"},"PeriodicalIF":0.0,"publicationDate":"2023-07-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"46718811","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Emilse Vazquez , Diego Nicita , Daniela Masini , Mario Matteo , Nora Costa , Osvaldo Franze , Norberto Trione , Marcelo Corti
{"title":"Mycobacterium genavense: una causa infrecuente de lesión cerebral ocupante de espacio","authors":"Emilse Vazquez , Diego Nicita , Daniela Masini , Mario Matteo , Nora Costa , Osvaldo Franze , Norberto Trione , Marcelo Corti","doi":"10.1016/j.neuarg.2022.03.001","DOIUrl":"10.1016/j.neuarg.2022.03.001","url":null,"abstract":"<div><h3>Introduction</h3><p>Patients with advanced HIV/AIDS disease are at high risk to developing opportunistic infections. Non-tuberculous mycobacterias (NTM), as <em>Mycobacterium genavense</em>, has been found to cause disseminated infection in patients with AIDS. These organisms are transmitted through inhalation and ingestion and cause serious infections in both, immunocompromised and immunocompetent hosts. We describe an unusual case of a patient with AIDS who presented with a cerebral mass lesion, which was found to be caused by infection with <em>M. genavense</em>.</p></div><div><h3>Clinical case</h3><p>A 49-year-old man, with a large history of advanced HIV/AIDS disease, and a background of disseminated infection due to a mycobacteria, not identify, two years before, with digestive tract, bone marrow and central nervous system involvement. He was started on antituberculous treatment extended to NTM. He was discharged but interrupted the controls and the treatment. Several months later, he returned with left omalgia without neurological symptoms. A computed tomography of the brain showed a right temporo-parietal mass with surrounding vasogenic edema, concerning for an abscess. Microbiological examination of the surgical piece showed the development of <em>M. genavense</em>.</p></div><div><h3>Conclusions</h3><p>We report a case of <em>M. genavense</em> brain abscess in a patient with advanced HIV/AIDS disease. Advanced HIV disease represents the most common risk factor for NTM infections. <em>M. genavense</em> is a very rare etiological agent of brain mass lesions in immunocompromised hosts. Stereotactic brain biopsy or neurosurgical exeresis of the brain abscess followed by the direct and culture examination of the material obtained are necessary to reach the etiological diagnosis and an adequate treatment according to the antibiogram. Additionally, we discuss the microbiology of this organism and review the literature on <em>M. genavense</em> infections.</p></div>","PeriodicalId":39051,"journal":{"name":"Neurologia Argentina","volume":"15 3","pages":"Pages 198-202"},"PeriodicalIF":0.0,"publicationDate":"2023-07-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"44962806","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Otto Vega , Facundo Escandón , Rocío Márquez , Juan Pablo Rodríguez , José Zuñiga , Natalia Balian , Alejandra Heriz
{"title":"Lesiones cerebrales limítrofes asociadas a síndrome de hipereosinofilia como causa infrecuente de accidente cerebrovascular isquémico: presentación de 3 casos","authors":"Otto Vega , Facundo Escandón , Rocío Márquez , Juan Pablo Rodríguez , José Zuñiga , Natalia Balian , Alejandra Heriz","doi":"10.1016/j.neuarg.2023.05.003","DOIUrl":"10.1016/j.neuarg.2023.05.003","url":null,"abstract":"<div><h3>Introduction</h3><p>Watershed infarcts are ischemic lesions that occur in a conjunction area between two principal arteries. The presence of bilateral strokes has been reported as an infrequent complication of hypereosinophilia, both in relation to an idiopathic hypereosinophilic syndrome or due to a parasite infection.</p></div><div><h3>Clinical case</h3><p>We present 3 patients with ischemic lesions in magnetic resonance (MRI), with findings of hypereosinophilia during workup study and bone marrow biopsies with eosinophilic hyperplasia.</p></div><div><h3>Conclusions</h3><p>It is relevant to remember the importance of a comprehensive study of the patients during etiological workup and to have in mind, especially in watershed strokes, the need not only to rule out the most frequent causes of ischemic strokes but also, in this cases, less common causes and the importance of performing an appropriate interpretation of initial studies such as a hemogram.</p></div>","PeriodicalId":39051,"journal":{"name":"Neurologia Argentina","volume":"15 3","pages":"Pages 235-240"},"PeriodicalIF":0.0,"publicationDate":"2023-07-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"44676442","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Camila Andrea Acosta Pérez , Luisa Ivonne Guerra Guerra , Ledmar Jovanny Vargas Rodríguez , Benjamín Alexander Márquez Rosales , María Teresa Alvarado
{"title":"Caracterización de los abscesos cerebrales en pacientes atendidos en un hospital universitario de alta complejidad","authors":"Camila Andrea Acosta Pérez , Luisa Ivonne Guerra Guerra , Ledmar Jovanny Vargas Rodríguez , Benjamín Alexander Márquez Rosales , María Teresa Alvarado","doi":"10.1016/j.neuarg.2023.04.002","DOIUrl":"10.1016/j.neuarg.2023.04.002","url":null,"abstract":"<div><h3>Introduction</h3><p>Cerebral or encephalic abscess, a focal infection of the brain parenchymal tissue that causes inflammation and necrosis, which leads to a circumscribed collection of purulent exudate.</p></div><div><h3>Objective</h3><p>To determine the clinical and sociodemographic characteristics of patients with brain abscesses treated in a high complexity hospital.</p></div><div><h3>Methods</h3><p>A descriptive observational study was carried out, which included people over 18 years of age with brain abscesses treated at the San Rafael de Tunja University Hospital who were identified by ICD 10 codes related to brain abscesses (A066, B431, and G060). Sociodemographic, clinical, paraclinical and therapeutic variables are included.</p></div><div><h3>Results</h3><p>Forty-three patients were included. 76.74% male, mean age 49.46 years (±22.49). The clinical presentation on admission is evaluated by the presence of headache and/or involvement of some mental sphere. The most frequent tomographic finding was in the frontal lobe in 37.2%.</p></div><div><h3>Conclusions</h3><p>It is a serious central nervous system (CNS) infection that can have great repercussions. They can be prevented if possible sources of initial infection are treated promptly. Once it is established, it is important to carry out therapeutic measures as soon as possible in order to quickly control the infection and reduce the sequelae.</p></div>","PeriodicalId":39051,"journal":{"name":"Neurologia Argentina","volume":"15 3","pages":"Pages 177-182"},"PeriodicalIF":0.0,"publicationDate":"2023-07-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"49462781","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Joselyn Miño , Alejandra Heriz , Rodrigo Sanjinez , Rocío Márquez , Juan Pablo Rodríguez , Otto Vega , José Zuñiga , Marcelo Rugiero
{"title":"Neuropatía craneana múltiple extensa rápidamente progresiva como variante de síndrome de Guillain-Barré: reporte de un caso","authors":"Joselyn Miño , Alejandra Heriz , Rodrigo Sanjinez , Rocío Márquez , Juan Pablo Rodríguez , Otto Vega , José Zuñiga , Marcelo Rugiero","doi":"10.1016/j.neuarg.2023.05.002","DOIUrl":"10.1016/j.neuarg.2023.05.002","url":null,"abstract":"<div><h3>Introduction</h3><p>The clinical presentation of Guillain-Barré syndrome can be heterogeneous due to its multiple variants, some defined and others that are part of the spectrum of the disease.</p></div><div><h3>Clinical case</h3><p>Thirty-five-year-old female who presented with multiple cranial neuropathy, with no other findings. Determination of antiganglioside antibodies in cerebrospinal fluid, positive for GD1b and GQ1b, was performed. Treatment with gamma globulin was performed with good response.</p></div><div><h3>Conclusion</h3><p>Multiple cranial neuropathy can occur in the context of Guillain-Barré variants, in relation to the case presented, the distribution of GD1b and GQ1b antibodies would explain the clinical presentation of the patient.</p></div>","PeriodicalId":39051,"journal":{"name":"Neurologia Argentina","volume":"15 3","pages":"Pages 231-234"},"PeriodicalIF":0.0,"publicationDate":"2023-07-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"42183153","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}