Neurologia Argentina最新文献

{"title":"Disparidades de salud en el mundo real de los pacientes con esclerosis múltiple","authors":"Roberto Rotta Escalante ,&nbsp;Osvaldo Fustinoni ,&nbsp;María Elisa Barone ,&nbsp;José R. Elli ,&nbsp;María del Carmen Martínez Perea ,&nbsp;Grupo de trabajo de Bioética de la Sociedad Neurológica Argentina","doi":"10.1016/j.neuarg.2023.02.001","DOIUrl":"10.1016/j.neuarg.2023.02.001","url":null,"abstract":"<div><h3>Introduction</h3><p>Many countries, developed or not, endure social, economic, cultural, ethnic, environmental and also health disparities.</p></div><div><h3>Objective</h3><p>To point out health disparities occurring in the real world care of patients with multiple sclerosis.</p></div><div><h3>Development</h3><p>Recently published data increasingly mention health disparities in multiple sclerosis obtained from real world data and not from randomized clinical trials. The most prevalent include limited access to specific medication, magnetic resonance imaging, other essential diagnostic studies, neurorehabilitation. Disregard of the various handicaps caused by the disease (poor quality of life, difficulties of daily living), age, gender, ethnicity, socioeconomic status, environment, dwelling and employment are also mentioned. Analyzed with adequate instruments, these data might have hard evidence value on health disparities, at present underestimated when assessing the care of patients with this disease, and consequently allowing for more scientifically rigorous diagnostic and therapeutic decisions.</p></div><div><h3>Conclusions</h3><p>Health disparities are relevant evidence in multiple sclerosis patients and should be included in the assessment and decision making of their management. Correcting them would contribute to a better equity in health care.</p></div>","PeriodicalId":39051,"journal":{"name":"Neurologia Argentina","volume":"15 1","pages":"Pages 37-46"},"PeriodicalIF":0.0,"publicationDate":"2023-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"46977629","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Migraña y ritmo delta intermitente de máximo anterior (FIRDA): un reporte de caso y revisión de tema","authors":"Andrés Felipe Morcillo Muñoz ,&nbsp;Daniel S. Marín-Medina ,&nbsp;Juan Camilo Castro-Rubio ,&nbsp;Pablo Lorenzana Pombo","doi":"10.1016/j.neuarg.2022.04.003","DOIUrl":"10.1016/j.neuarg.2022.04.003","url":null,"abstract":"<div><h3>Introduction</h3><p>Migraine sometimes coexist with epilepsy. The electroencephalography correlation about the migraine patients had found the presence of frontal intermittent rhythmic delta activity (FIRDA) its recognition has diagnostic and therapeutic implications.</p></div><div><h3>Clinical case</h3><p>38 years old women with a history of migraine with aura with an increase of its frequency and intensity in association with episodes of anterograde amnesia, confusion and temporal and spatial disorientation besides paresthesias, a 4 hours video-electroencephalograph showed FIRDA trains.</p></div><div><h3>Conclusions</h3><p>The relation among migraine and FIRDA has been controversial, recently it is stablished as a cortical dysfunction of medial structures associated with attention and awareness state.</p></div>","PeriodicalId":39051,"journal":{"name":"Neurologia Argentina","volume":"15 1","pages":"Pages 47-51"},"PeriodicalIF":0.0,"publicationDate":"2023-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"45909115","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Salud mental de cuidadores de niños con trastornos del neurodesarrollo durante la pandemia","authors":"Jorge Emiro Restrepo ,&nbsp;Tatiana Castañeda-Quirama ,&nbsp;Mónica Gómez-Botero ,&nbsp;David Molina-González","doi":"10.1016/j.neuarg.2022.12.004","DOIUrl":"10.1016/j.neuarg.2022.12.004","url":null,"abstract":"<div><p>Caregivers are especially likely to be more psychologically affected during the social and health care system constraints generated by the COVID-19 pandemic. Caregivers of children with neurodevelopmental disorders (i.e., autism, intellectual disability, attention deficit, hyperactivity, motor disability) have a more essential role than caregivers of healthy children. A quantitative cross-sectional study was designed, using descriptive, comparative and correlational statistical techniques to analyze health-related quality of life, emotional distress and overload in four subgroups of caregivers, classified according to the child's diagnosis. A total of 132 caregivers (86.4% women) were included. In group<!--> <!-->1 (cognitive disability), 28 caregivers participated; in group<!--> <!-->2 (ADHD), 51 were included; in group<!--> <!-->3 (autism spectrum disorder), 33 caregivers participated, and in group<!--> <!-->4 (motor disability), 20 were included. The main findings of this study were: i)<!--> <!-->alterations in physical role, bodily pain, general health and vitality; ii)<!--> <!-->very low percentages of depression, anxiety, stress and overload symptomatology; iii)<!--> <!-->differences in social functioning between the motor disability and ADHD groups; and in stress and overload between the autism and motor disability groups; and iv)<!--> <!-->moderate correlations between the dimensions of bodily pain and emotional role and depression, anxiety, stress and overload. It was concluded that there is more impairment in variables associated with physical health than with mental health.</p></div>","PeriodicalId":39051,"journal":{"name":"Neurologia Argentina","volume":"15 1","pages":"Pages 28-36"},"PeriodicalIF":0.0,"publicationDate":"2023-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"46000392","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Melanosis neurocutánea: a propósito de dos casos","authors":"Rosmery Villa Delgado ,&nbsp;Carlos Campo Ternera ,&nbsp;Dagoberto Cabrera Nicanor","doi":"10.1016/j.neuarg.2022.07.006","DOIUrl":"10.1016/j.neuarg.2022.07.006","url":null,"abstract":"<div><p>Neurocutaneous melanosis is a congenital disorder of the development of melanocytic cells that involves the central nervous system. The neuraxis MRI is mandatory in every newborn with a high-risk congenital melanocytic nevus to rule out neurological involvement so that adequate follow-up by a pediatric neurologist can be offered. Our objective is to report two cases of children with giant congenital melanocytic nevus with trunk distribution, one of them associated with myelomeningocele. MRI showed multiple hyperintense lesions of the brain parenchyma and leptomeninges confirming the diagnosis.</p></div>","PeriodicalId":39051,"journal":{"name":"Neurologia Argentina","volume":"15 1","pages":"Pages 61-65"},"PeriodicalIF":0.0,"publicationDate":"2023-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"46500099","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Hemimegalencefalia como hallazgo incidental: presentación de un caso","authors":"Esteban Spadaro ,&nbsp;Silvina Rubiolo ,&nbsp;Ricardo Theaux ,&nbsp;Manuel Albarenque","doi":"10.1016/j.neuarg.2022.10.001","DOIUrl":"10.1016/j.neuarg.2022.10.001","url":null,"abstract":"<div><p>Hemimegalencephaly is a rare and severe malformation of a cerebral hemisphere whose usual clinical presentation is refractory epilepsy, mental retardation and hemiparesis.</p><p>This work describes the case of a 51-year-old woman with normal cognitive development, a secondary school teacher with migraines, who consults due to changes in the characteristics of her headache, after a covid infection. In the study by nuclear magnetic resonance (MRI) of the brain, the presence of a hemimegalencephaly is discovered.</p><p>The objective of this work is to present an asymptomatic patient, in whom an incidental diagnosis of hemimegalencephaly is made.</p></div>","PeriodicalId":39051,"journal":{"name":"Neurologia Argentina","volume":"14 4","pages":"Pages 263-265"},"PeriodicalIF":0.0,"publicationDate":"2022-10-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"43158208","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Efectos de la pandemia por COVID-19 con relación al ACV isquémico. ¿La pandemia realmente lo cambió todo? Un estudio comparativo pre-post COVID-19 con revisión de la literatura","authors":"Julián Fernández Boccazzi,&nbsp;Xavier Merchán del Hierro,&nbsp;Gabriel Persi,&nbsp;Josefina Seguí,&nbsp;Victoria Aldinio,&nbsp;Santiago Muniagurria,&nbsp;Jonathan Cubas Guillen,&nbsp;Emilia M. Gatto,&nbsp;Afra Gilbert,&nbsp;Nahuel Pereira de Silva","doi":"10.1016/j.neuarg.2022.08.004","DOIUrl":"https://doi.org/10.1016/j.neuarg.2022.08.004","url":null,"abstract":"<div><h3>Introduction and objectives</h3><p>Ischemic stroke is the third leading cause of death and the first cause of disability in the world. Since March 2020, the COVID-19 pandemic has generated changes in daily medical practice, as well as an impact on access to health centers.</p><p>The objective of this study is to evaluate the effect of the COVID-19 pandemic on the number of admissions, consultation time and treatment rates of stroke in our center.</p></div><div><h3>Materials and methods</h3><p>Descriptive and retrospective study, with 115 patients between March 2019 and March 2021. Clinical characteristics, admissions time, severity and treatment rates pre-pandemic and during the same were compared.</p></div><div><h3>Results</h3><p>Both groups presented mild events (71% vs. 59%, <em>P</em> <!-->&gt;<!--> <!-->.05). There was an increase in the time from consultation to initiation of thrombolysis therapy during the pandemic (median 2.1 vs. 3.5<!--> <!-->h, <em>P</em> <!-->=<!--> <!-->.02). No significant differences were observed in reperfusion rates, consultation time and door-to-needle time.</p></div><div><h3>Conclusion</h3><p>In our study, a significant difference was observed between the time of symptom onset and treatment with thrombolysis during the pandemic. On the other hand, no significant differences were observed in relation to the number of admissions, consultation time and door-to-needle time or treatment rate of patients with stroke during the COVID-19 pandemic.</p><p>We believe that this work can provide an approach to epidemiology in the private regional setting and a potential basis for further analysis of the collateral damage and long-term consequences generated by the COVID-19 pandemic.</p></div>","PeriodicalId":39051,"journal":{"name":"Neurologia Argentina","volume":"14 4","pages":"Pages 244-250"},"PeriodicalIF":0.0,"publicationDate":"2022-10-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.sciencedirect.com/science/article/pii/S1853002822000507/pdfft?md5=0e49d4861a5a4e2d483ba51e5c6d4d45&pid=1-s2.0-S1853002822000507-main.pdf","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"136513517","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Síndrome del acento extranjero secundario a resección de glioblastoma; reporte de caso y revisión de la literatura","authors":"Jose Ricardo Muñoz-Zuñiga ,&nbsp;Valeria Valencia-Cifuentes ,&nbsp;Alberto Masaru Shinchi-Tanaka","doi":"10.1016/j.neuarg.2022.07.009","DOIUrl":"10.1016/j.neuarg.2022.07.009","url":null,"abstract":"<div><p>Foreign accent syndrome is a speech disorder where the person articulates their native language with an accent that is perceived as non-native. It is characterized by contrasting segmental and prosodic deficits in normal phonological parameters without violating grammatical rules. Until 2015 there were only 105 reported cases: mostly English related cases. We present the case of a Spanish user, who after a tumor resection, presents a foreign accent syndrome of neurogenic origin, with subsequent review of the topic and complementary multimedia material.</p></div>","PeriodicalId":39051,"journal":{"name":"Neurologia Argentina","volume":"14 4","pages":"Pages 260-262"},"PeriodicalIF":0.0,"publicationDate":"2022-10-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"48349307","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Caracterización del síndrome de Guillain-Barré en pacientes atendidos en un hospital en Colombia entre el año 2009 y el 2019","authors":"Benjamín Alexander Márquez Rosales ,&nbsp;Ledmar Jovanny Vargas Rodríguez ,&nbsp;Luisa Ivonne Guerra Guerra","doi":"10.1016/j.neuarg.2021.10.003","DOIUrl":"10.1016/j.neuarg.2021.10.003","url":null,"abstract":"<div><h3>Introduction</h3><p>Guillain-Barré syndrome (GBS) is an acute inflammatory polyradiculoneuropathy in which there is a state of autoimmunity towards the myelin sheath of peripheral nerves, generating a distinctive clinical picture. This pathology is associated with multiple factors.</p></div><div><h3>Objective</h3><p>To characterize the patients with GBS treated at the San Rafael de Tunja University Hospital between 2009 and 2019.</p></div><div><h3>Methods</h3><p>Analytical observational study, in patients older than 18 years with GBS treated between January 1, 2009 and September 17, 2019, with ICD-10 code G610. Sociodemographic, clinical, paraclinical, imaging, electrophysiological and therapeutic variables were evaluated.</p></div><div><h3>Results</h3><p>Eighty-six patients were included, 51 of them were men, presenting more frequently in people of urban origin (63.9%), low socioeconomic status (67.4%), with a history of gastrointestinal (65.1%) or respiratory disease (30.2%). Electromyography was abnormal electromyography in 84.8% of cases, 97.6% presented hyperproteinorrachia and 96.5% had cytological albumine dissociation. The evolution time was different according to the variant: 7 days for AMAN and AMSAN, 77 days for Miller Fisher and 113 days for AIDP, among others.</p></div><div><h3>Conclusions</h3><p>This is a pathological entity that is associated with different etiological factors such as infectious conditions, trauma, etc. It occurs most often in the male sex. The diagnostic criteria are clear and have good operational characteristics. Currently there are no studies that explain how each factor favors the presentation of GBS, so it is recommended to conduct studies of greater hierarchy to evaluate this association.</p></div>","PeriodicalId":39051,"journal":{"name":"Neurologia Argentina","volume":"14 4","pages":"Pages 208-214"},"PeriodicalIF":0.0,"publicationDate":"2022-10-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"46159543","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Utilización de ventilación no invasiva en pacientes con esclerosis lateral amiotrófica","authors":"Eduardo Borsini ,&nbsp;Magalí Blanco ,&nbsp;Glenda Ernst ,&nbsp;Josefina Pascua ,&nbsp;Alejandro Salvado ,&nbsp;Ricardo Reisin","doi":"10.1016/j.neuarg.2022.04.004","DOIUrl":"10.1016/j.neuarg.2022.04.004","url":null,"abstract":"<div><h3>Introduction</h3><p>Patients with amyotrophic lateral sclerosis need a multidimensional approach to alleviate their decreased respiratory performance. In order to describe the ventilatory support (NIV) implemented in a day hospital and health resources consumption, we review our experience during 4 years.</p></div><div><h3>Patients and methods</h3><p>We included 27 patients; 19 men (70.4%), mean age 62.0<!--> <!-->±<!--> <!-->14.1 years. A percentage of 48.1 debuted due to bulbar symptoms (ELA_B) and the spinal form (ELA_S) represented 51.9%.</p></div><div><h3>Results</h3><p>Sixteen received NIV on the first visit and 7 during follow-up. Four (14.8%) accepted the tracheostomy. The most used ventilatory mode was barometric with backup rate (S/T) without supplemental O₂. Expiratory positive pressure was 5.6 cmH₂O (25-75 percentile of 5-7) and inspiratory positive pressure was 14.7 cmH₂O (25-75 percentile of 12-17). Oronasal masks were used predominantly. Compliance of NIV was 8.7<!--> <!-->±<!--> <!-->2.6<!--> <!-->h/day. PaCO₂ in the first 3 visits (9 months with NIV) was maintained stable (47.5 vs. 49.0 vs. 38.5 mmHg; <em>P</em> <!-->=<!--> <!-->.27). Twenty-four hospitalizations were recorded (1.1<!--> <!-->±<!--> <!-->1.4 episodes/patient) without differences between previous year and follow-up (<em>P</em> <!-->=<!--> <!-->.78), although the hospital stay was reduced (<em>P</em> <!-->=<!--> <!-->.03) without differences between ELA_B and ELA_S. We registered 12 deaths during follow-up (mortality 52.2%), 10 of them at home due to advance directives.</p></div><div><h3>Conclusions</h3><p>This population showed acceptance of NIV and the hospitalization days were reduced in the follow-up. Compliance was adequate and related to gasometric stability in the medium term.</p></div>","PeriodicalId":39051,"journal":{"name":"Neurologia Argentina","volume":"14 4","pages":"Pages 221-228"},"PeriodicalIF":0.0,"publicationDate":"2022-10-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"41694381","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Caracterizando al enemigo: Infecciones oportunistas en el sistema nervioso central en pacientes con VIH, una serie de casos colombiana","authors":"Carlos Castro-Vásquez ,&nbsp;Diana C. Maldonado ,&nbsp;Paula Arboleda ,&nbsp;Manuel Camargo ,&nbsp;Omar Chavarro ,&nbsp;Gustavo Díaz ,&nbsp;Andrea C. Buitrago ,&nbsp;Habib Georges Moutran","doi":"10.1016/j.neuarg.2021.10.004","DOIUrl":"10.1016/j.neuarg.2021.10.004","url":null,"abstract":"<div><h3>Introduction</h3><p>The opportunistic infections continue to be one of the main causes of morbidity and mortality in HIV-positive; additionally, the central nervous system is one of the most frequently compromised systems. Despite this and the high AIDS mortality rate in Colombia, there are only a few studies that characterize the opportunistic infections of the central nervous system in HIV-positive patients in the country.</p></div><div><h3>Objective</h3><p>To describe the opportunistic infections in the central nervous system and its associated demographic factors in HIV-positive patients, treated in a public hospital of Bogotá.</p></div><div><h3>Materials and methods</h3><p>This study is a retrospective case series study of HIV-AIDS patients hospitalized at Santa Clara Hospital in 2015-2016. Both clinical, paraclinical and demographic variables were collected and a description was made by etiologic agent using the Chi2 test, student t, Mann-Whitney U, ANOVA or Kruskal Wallis (statistical significance of <em>P</em> <!-->&lt;<!--> <!-->0.05)</p></div><div><h3>Results</h3><p>From 538 HIV-AIDS patients, 56 had an opportunistic infection of the central nervous system. Most of them were men, with a mean age of 37,96 (SD 9,96). The average CD4 count was 74<!--> <!-->cells/μL and the most prevalent neuroinfection was cerebral Toxoplasmosis.</p></div><div><h3>Conclusions</h3><p>Central nervous system infections, diagnosed at Hospital Santa Clara, were associated with more than one etiologic agent in some of the patients. The most frequently found infections were caused by <em>Toxoplasma gondii</em> and <em>Cryptococcus neoformans</em>; which had high percentages of mortality and clinical associated complications.</p></div>","PeriodicalId":39051,"journal":{"name":"Neurologia Argentina","volume":"14 4","pages":"Pages 215-220"},"PeriodicalIF":0.0,"publicationDate":"2022-10-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"47278047","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}