Presentación atípica en resonancia de cerebro de la enfermedad de Creutzfeldt-Jakob: reporte de un caso

Introduction

Creutzfeldt-Jakob disease is a rare, progressive and fatal spongiform encephalopathy that is caused by a prion. In 2010, the MRI findings were included in the criteria for diagnosing the disease. We describe a patient with an atypical presentation in images.

Clinical case

73-year-old patient with rapidly progressive dementia and brain MRI with hyperintensity in the limbic system. The patient evolves with akinetic mutism and death 5 months after the onset of the clinical picture.

Conclusions

Magnetic resonance imaging is a fundamental pillar in the diagnostic evaluation of patients with rapidly progressive dementia and, in particular, in the differential diagnosis between Creutzfeldt-Jakob disease and autoimmune encephalitis.