Revista de la Facultad de Ciencias Medicas de Cordoba最新文献_第6页

Effect of training on bone quality in rats with insulin resistance induce by fluoride consumption. 训练对服用氟化物导致胰岛素抵抗的大鼠骨骼质量的影响

Revista de la Facultad de Ciencias Medicas de Cordoba Pub Date : 2024-06-28 DOI: 10.31053/1853.0605.v81.n2.42505

Mercedes Lombarte, Brenda Lorena Fina, Victoria Inés García, Maela Lupo, Alfredo Rigalli

引用次数: 0

[Spanish translation, cross-cultural adaptation and validation of the ADTC scale (Atopic Dermatitis Control Tool)] [特应性皮炎控制工具（ADTC）量表的西班牙文翻译、跨文化改编和验证］

Revista de la Facultad de Ciencias Medicas de Cordoba Pub Date : 2024-06-28 DOI: 10.31053/1853.0605.v81.n2.42369

Mariana Paula Caviedes, María Valeria Angles, Paula Carolina Luna, Sergio Terrasa, Fernando Vazquez Peña, Cristina Echeverria, Margarita Larralde, Luis Daniel Mazzuoccolo

{"title":"[Spanish translation, cross-cultural adaptation and validation of the ADTC scale (Atopic Dermatitis Control Tool)]","authors":"Mariana Paula Caviedes, María Valeria Angles, Paula Carolina Luna, Sergio Terrasa, Fernando Vazquez Peña, Cristina Echeverria, Margarita Larralde, Luis Daniel Mazzuoccolo","doi":"10.31053/1853.0605.v81.n2.42369","DOIUrl":"10.31053/1853.0605.v81.n2.42369","url":null,"abstract":"Introduction: Objetives: Obtain a version to validate it in a population of adults with AD.Materials and methods: 1) Translation into Spanish and cross-cultural adaptation of the questionnaire from the original version in English, through a seven-step process. 2) Evaluation of the unidimensionality of the resulting scale by means of an exploratory factor analysis (EFA), of its reliability by means of Cronbach's alpha coefficient, and of its validity by evaluating the correlation of its score with those of the POEM and DLQI questionnaires. (external reference criteria).Results: The version resulting from the translation and cross-cultural adaptation process was well understood by the target population. The AFE of the 66 questionnaires documented the unidimensionality of the scale based on compliance with all the criteria used for its verification. Its reliability was excellent (Cronbach's Alpha: 0.917) and its score had a very high correlation with the external reference criteria (POEM: Spearman's Rho 0.85; p < 0.0001; DLQI Spearman's Rho = 0.81; p < 0 .0001).Conclusions: The version translated into Spanish and adapted for transculturation of the ADCT questionnaire has appropriate psychometric characteristics, which will contribute to optimizing the care processes of Spanish-speaking patients.","PeriodicalId":38814,"journal":{"name":"Revista de la Facultad de Ciencias Medicas de Cordoba","volume":"81 2","pages":"285-301"},"PeriodicalIF":0.0,"publicationDate":"2024-06-28","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11370881/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141471321","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

[Cirrhotic cardiomyopathy – Clinically fact or academic curiosity? Review.Part 2: ECG, functional tests, images, biomarkers, screening for coronary heart disease and differentianting diagnosis] [肝硬化性心肌病--临床事实还是学术好奇？回顾。第二部分：心电图、功能测试、图像、生物标志物、冠心病筛查和分型诊断］

Revista de la Facultad de Ciencias Medicas de Cordoba Pub Date : 2024-06-28 DOI: 10.31053/1853.0605.v81.n2.44419

Hugo Ramos, Mario Altieri

引用次数: 0

[Severe hypereosinophilia as a paraneoplastic syndrome in a patient with differentiated thyroid cancer] [严重的嗜酸性粒细胞增多症是分化型甲状腺癌患者的一种副肿瘤综合征］

Revista de la Facultad de Ciencias Medicas de Cordoba Pub Date : 2024-06-28 DOI: 10.31053/1853.0605.v81.n2.44472

Elizabeth Karen Videla, Bertha De la Torre, Pablo Ferrada, Jorge Miller, Eduardo Torres, Analía Álvarez, Javier Herrera

{"title":"[Severe hypereosinophilia as a paraneoplastic syndrome in a patient with differentiated thyroid cancer]","authors":"Elizabeth Karen Videla, Bertha De la Torre, Pablo Ferrada, Jorge Miller, Eduardo Torres, Analía Álvarez, Javier Herrera","doi":"10.31053/1853.0605.v81.n2.44472","DOIUrl":"10.31053/1853.0605.v81.n2.44472","url":null,"abstract":"In solid tumors, hypereosinophilia is a rare phenomenon and is mainly associated with mucin-secreting carcinomas. Thyroid tumors associated with neutrophilia and/or eosinophilia have been described exclusively in patients with anaplastic thyroid cancer. Eosinophilia associated with papillary thyroid cancer is extremely rare and there are very few cases currently described. It has been suggested that three cytokines, namely interleukin-3 (IL-3), interleukin-5 (IL-5), and granulocyte-macrophage colony-stimulating factor (GM-CSF), may act as a peptide potential eosinophilic. To date, only three patients with differentiated thyroid cancer associated with eosinophilia have been reported, two of the papillary type and one of the medullary type. A 48-year-old patient consulted in 2022 due to bilateral cervical lymphadenopathy of 3 years' duration associated with wasting syndrome and hypereosinophilia. PET CT was requested, which showed hypermetabolic focus in the right thyroid lobe and lymph node, lung, bone, and liver metastases; Thyroid ultrasound showing a nodule of high suspicion of malignancy and a conglomerate of lymphadenopathy in the right lobe with positive needle wash for thyroglobulin. Hypereosinophilia was evaluated with initial leukocytosis values of GB 30,310/mm3 (10,608/mm3 of eosinophils) to maximum values of GB 77,090/mm3 (eosinophils 20,814/mm3). It was interpreted as paraneoplastic syndrome and corticosteroid therapy was started at immunosuppressive doses without response. Our observations presented in this article are in line with most studies reflecting that paraneoplastic hypereosinophilia is characterized by more advanced disease and poor prognosis.","PeriodicalId":38814,"journal":{"name":"Revista de la Facultad de Ciencias Medicas de Cordoba","volume":"81 2","pages":"403-414"},"PeriodicalIF":0.0,"publicationDate":"2024-06-28","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11370870/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141471320","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

[Off-label use of intravenous immunoglobulin g in a highly complex pediatric hospital in Argentina. A prospective observational study] [阿根廷一家高度复杂的儿科医院在标签外使用静脉注射免疫球蛋白 g。前瞻性观察研究］

Revista de la Facultad de Ciencias Medicas de Cordoba Pub Date : 2024-06-28 DOI: 10.31053/1853.0605.v81.n2.42261

Roxana Rivero, Ingrid Strusberg, Silvia Joekes, Silvana Yori, Carolina Barros Herrero, Marcela Noemí Rousseau, Daniela Fontana

{"title":"[Off-label use of intravenous immunoglobulin g in a highly complex pediatric hospital in Argentina. A prospective observational study]","authors":"Roxana Rivero, Ingrid Strusberg, Silvia Joekes, Silvana Yori, Carolina Barros Herrero, Marcela Noemí Rousseau, Daniela Fontana","doi":"10.31053/1853.0605.v81.n2.42261","DOIUrl":"10.31053/1853.0605.v81.n2.42261","url":null,"abstract":"Introduction: The World Health Organization recommends prioritizing safe and effective drugs proven by clinical or epidemiological studies. However, in population groups with little research, a drug can be used for an indication or pharmaceutical form different from that approved by the regulatory agency (off-label), extrapolating data from studies in adults and exposing pediatric patients. to develop an Adverse Drug Reaction (ADR) due to safety considerations that have not been systematically studied. Intravenous immunoglobulin (IVIg), a high-cost drug, is used with scant evidence in some low-prevalence pathologies. This paper describes and analyzes the off-label use of IVIg at the J. P. Garrahan Pediatric Hospital.Methods: Observational, descriptive, prospective study on off-label indications of IVIg. The sampling technique was non-probabilistic and for convenience during 7 months.Results: 305 IVIg infusions were studied, corresponding to 111 patients. The indication classification showed that 22% (n=67) of the infusions were off-label. In neurology there was a higher percentage of off-label indications (46%) and within them 45% corresponded to the use in neurological disorders. 81% of the doses indicated off-label were in the range 0.8-1g/kg. The off-label infusions presented 61.5% (n=8) of the ADRs. Those from the Neurology service represented 87.5%; 75% being from the \"Neurological disorders\" group.Conclusion: In some cases, IVIg was indicated in an off-label manner, finding a statistically significant relationship with the appearance of ADR. This finding motivates the proposition of new hypotheses to carry out more studies.","PeriodicalId":38814,"journal":{"name":"Revista de la Facultad de Ciencias Medicas de Cordoba","volume":"81 2","pages":"254-269"},"PeriodicalIF":0.0,"publicationDate":"2024-06-28","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11370868/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141471316","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

[Primary immune thrombocytopenia linked to the ingestion of guinea pigs (Cavia porcellus)causality or coincidence?] [原发性免疫性血小板减少症与摄入豚鼠（Cavia porcellus）有关，是因果关系还是巧合？］

Revista de la Facultad de Ciencias Medicas de Cordoba Pub Date : 2024-06-28 DOI: 10.31053/1853.0605.v81.n2.44592

Héctor Chiang Wong, María Del Carmen González Guzmán, Patricio González Saldaña

引用次数: 0

[Cerebral gas embolism as a complication of diffuse interstitial lung disease] [作为弥漫性间质性肺病并发症的脑气体栓塞］

Revista de la Facultad de Ciencias Medicas de Cordoba Pub Date : 2024-06-28 DOI: 10.31053/1853.0605.v81.n2.42414

Juan Ramon Y Cajal Calvo, Laura Perez Abad, Victoria Mayoral Campos, Beatriz Carro Alonso

{"title":"[Cerebral gas embolism as a complication of diffuse interstitial lung disease]","authors":"Juan Ramon Y Cajal Calvo, Laura Perez Abad, Victoria Mayoral Campos, Beatriz Carro Alonso","doi":"10.31053/1853.0605.v81.n2.42414","DOIUrl":"10.31053/1853.0605.v81.n2.42414","url":null,"abstract":"Introduction: Cerebral gas embolism is an unusual but extremely serious condition that occurs when air is introduced into the arterial or venous circulation of the brain. Although rare, it can lead to significant neurological deficits and even the death of the patient.Clinical case: 76-year-old patient with pre-existing diffuse interstitial lung disease, who experienced a massive stroke due to spontaneous pneumomediastinum. Her presentation included confusion, seizures, and motor weakness. Imaging tests revealed air bubbles in the cerebral sulci and hypodense areas in the cerebellum and parietooccipitals. In addition, pneumothorax and air in the upper mediastinum were noted on chest radiographs and chest CT scan. Despite therapeutic measures such as hyperbaric oxygen, the patient unfortunately died due to multiple organ failure.Discussion: The diagnosis of cerebral gas embolism generally involves performing a cerebral computed tomography, which is highly sensitive for detecting the presence of air in the cerebral vessels. Management includes monitoring of vital and neurological signs, as well as specific measures such as airway closure, venous catheter aspiration, Trendelenburg positioning, and hyperbaric oxygen.Conclusion: Cerebral gas embolism is a potentially fatal condition that requires a brain computed tomography for diagnosis and it is vitally important to know the prevention measures to avoid the appearance of this complication and also to know the general measures to adopt when it occurs.","PeriodicalId":38814,"journal":{"name":"Revista de la Facultad de Ciencias Medicas de Cordoba","volume":"81 2","pages":"381-390"},"PeriodicalIF":0.0,"publicationDate":"2024-06-28","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11370872/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141471346","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

[Characterization and risk prediction of cardiovascular surgeries with cardiopulmonary bypass: a cross-sectional study] [心肺旁路心血管手术的特征和风险预测：一项横断面研究］

Revista de la Facultad de Ciencias Medicas de Cordoba Pub Date : 2024-06-28 DOI: 10.31053/1853.0605.v81.n2.42432

Maria Teresa Politi, Sarah Di Benedetto, Raúl Ferreyra, Guillermo Bortman, Antonio Piazza, Claudia Capurro

{"title":"[Characterization and risk prediction of cardiovascular surgeries with cardiopulmonary bypass: a cross-sectional study]","authors":"Maria Teresa Politi, Sarah Di Benedetto, Raúl Ferreyra, Guillermo Bortman, Antonio Piazza, Claudia Capurro","doi":"10.31053/1853.0605.v81.n2.42432","DOIUrl":"10.31053/1853.0605.v81.n2.42432","url":null,"abstract":"Introduction: Cardiovascular surgery risk prediction models are widely applied in medical practice. However, they have been criticized for their low methodological quality and scarce external validation. An additional limitation added in Latin America is that most of these models have been developed in the United States or Europe, which present marked geographical differences. The objective of this study is to characterize the postoperative clinical events of cardiovascular surgeries with the use of cardiopulmonary bypass pump in a local setting and to evaluate the prediction of postoperative mortality using the EuroSCORE II predictive model.Methods: Cross-sectional study in an urban university hospital in Buenos Aires. Patients ≥21 years of age were included, with a clinical indication for on-pump cardiovascular surgery. Patients with incomplete clinical data regarding EuroSCORE II variables or in-hospital survival, ≥95 years of age, or undergoing heart transplantation were excluded.Results: 195 patients were enrolled. Postoperative mortality estimated by EuroSCORE II presented a clear underestimation of risk (3.0% vs 7.7%). Discrimination (AUC = 0.82; 95% CI 0.74-0.92) and goodness of fit of the model were adequate (χ2 = 7.91; p = 0.4418). The most frequent postoperative complications were postoperative heart failure (35.9%), vasoplegic shock (13.3%), and cardiogenic shock (10.26%).Conclusion: The EuroSCORE II is an appropriate tool to discriminate between different risk categories in patients undergoing on-pump cardiovascular surgery, although it underestimates the risk.","PeriodicalId":38814,"journal":{"name":"Revista de la Facultad de Ciencias Medicas de Cordoba","volume":"81 2","pages":"233-253"},"PeriodicalIF":0.0,"publicationDate":"2024-06-28","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11370882/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141471347","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

[The Metabolic syndrome and metabolic characteristics in blood donors] [献血者的代谢综合征和代谢特征］

Revista de la Facultad de Ciencias Medicas de Cordoba Pub Date : 2024-06-28 DOI: 10.31053/1853.0605.v81.n2.42446

Pedro Aro, Rodrigo Paredes, Grace Tello, Christian Lezama, Ana Oyola, Lesly Talavera, Max Acosta, Milton Tello

{"title":"[The Metabolic syndrome and metabolic characteristics in blood donors]","authors":"Pedro Aro, Rodrigo Paredes, Grace Tello, Christian Lezama, Ana Oyola, Lesly Talavera, Max Acosta, Milton Tello","doi":"10.31053/1853.0605.v81.n2.42446","DOIUrl":"10.31053/1853.0605.v81.n2.42446","url":null,"abstract":"Introduction: Metabolic syndrome (MS) is associated with increased cardiovascular risk. Blood donors are an apparently healthy population in which certain cardiometabolic characteristics are not evaluated in their selection, and there is limited information on their presence.Aim: To determine the frequency of metabolic syndrome and its metabolic characteristics in blood donors. Materials and methods: Cross-sectional study was carried in a population of 244 blood donors between 18 and 55 years of age who attended the Hemotherapy and Blood Bank Service of the Cayetano Heredia Hospital in Lima, Perú during the month of May 2023. The diagnosis of MS was made according to the Adult Treatment Panel III (ATP III) criteria. A bivariate analysis was performed between MS and metabolic characteristics with sex and a significance level of 5% was considered.Results: 63.9% of blood donors were male. 43.6% of the population had MS. The most frequent characteristics found were hypertriglyceridemia (54.5%), abdominal obesity (51.2%) and high-density lipoprotein (HDL) low (48.8%). The age range of 40 to 49 years presented the highest frequency of MS (14.3%). Hypertriglyceridemia and high blood pressure were associated with male sex (p=0.003 and p=0.019 respectively), while low HDL was associated with female sex (p<0.001).Conclusions: Blood donors present an elevated frequency of MS. The detection of MS in apparently healthy populations as part of primary care could allow the formulation of strategies for early detection of cardiovascular risk factors.","PeriodicalId":38814,"journal":{"name":"Revista de la Facultad de Ciencias Medicas de Cordoba","volume":"81 2","pages":"302-317"},"PeriodicalIF":0.0,"publicationDate":"2024-06-28","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11370876/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141471323","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

[Food consumption patterns and risk of gallstone disease (GD): Case and Control Study in Rosario Argentina.] [食物消费模式与胆石症（GD）风险：阿根廷罗萨里奥的病例与对照研究]

Revista de la Facultad de Ciencias Medicas de Cordoba Pub Date : 2024-06-28 DOI: 10.31053/1853.0605.v81.n2.36961

Agustina Bertola Compagnucci, Herman A Perroud, Stella M Batallés, Roberto Villavicencio, Daniel E Berli, Stella M Pezzotto

{"title":"[Food consumption patterns and risk of gallstone disease (GD): Case and Control Study in Rosario Argentina.]","authors":"Agustina Bertola Compagnucci, Herman A Perroud, Stella M Batallés, Roberto Villavicencio, Daniel E Berli, Stella M Pezzotto","doi":"10.31053/1853.0605.v81.n2.36961","DOIUrl":"10.31053/1853.0605.v81.n2.36961","url":null,"abstract":"Introduction: Nutritional exposure is considered the main environmental influence that contributes to gallstone disease (GD).Aim: The aim of this study was to determine food intakes patters and estimate risk of GD.Methods: A nested case-control study was carried out within the framework of a previous screening study conducted on a representative sample in Rosario, Argentina. Participants underwent a personal interview. Average amount of each food intake and quantity nutrients were estimated applying a food-frequency questionnaire. Food consumption patterns were identified by principal component analysis, and logistic regression analysis was used to estimate risks.Results: The sample was conformed by 51 cases and 69 controls. Two dietary patterns were identified. Cases were characterised by the unhealthy intake pattern (high intakes of animal fats, sugar, cereals, grains, cold cuts, processed meats, chicken with skin, fat beef and low intake of red vegetables and yellows, cabbages, fruits and fish).Conclusion: Controls were characterised by the healthy intake pattern (high intake of skinless chicken, nuts, lean beef, vitamin A and C rich fruits, and low consumption of chicken with skin, green leaves vegetables and sprouts). The unhealthy pattern showed an increased risk of developing GD while healthy patter behaved as a protective factor.","PeriodicalId":38814,"journal":{"name":"Revista de la Facultad de Ciencias Medicas de Cordoba","volume":"81 2","pages":"353-369"},"PeriodicalIF":0.0,"publicationDate":"2024-06-28","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11370879/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141471351","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0