Dental Press Journal of Orthodontics最新文献

{"title":"In vitro evaluation of biofilm formation by Streptococcus mutans and Candida albicans in orthodontic aligners.","authors":"Carolina Veronez Garbúggio Sanches, Raquel Sano Suga Terada, Adilson Luiz Ramos, Janaina de Cássia Orlandi Sardi, Maria Gabriely Malveiro Esteves, Maria Cristina Bronharo Tognim, Sheila Alexandra Belini Nishiyama","doi":"10.1590/2177-6709.30.2.e2524192.oar","DOIUrl":"10.1590/2177-6709.30.2.e2524192.oar","url":null,"abstract":"<p><strong>Introduction: </strong>Aligners have been used by the orthodontic community for approximately 20 years, but little research has been carried out on the accumulation of biofilm on the surface of these aligners, as well as their possible impact on the oral ecosystem.</p><p><strong>Methods: </strong>Ten hemi-arches of Invisalign® brand orthodontic aligners were used. The hemi-arches were placed inside sterile flasks containing 25 mL of Gibbons and Nygaard broth, with standardized suspensions of the two microorganisms on the 0.5 MacFarland scale and incubated in aerophily (C. albicans) and microaerophily (S. mutans and mixed biofilm) at 37°C for 72h. The biofilm formed was removed by the multiple rinses method to quantify the microorganisms in the biofilms in CFU/mL. A qualitative analysis with scanning electron microscopy was performed to observe the structure of the formed biofilms.</p><p><strong>Results: </strong>It was observed the accumulation of a monospecies biofilm (S. mutans - 2.55 x 106 and C. albicans - 1.62 x 107) and mixed biofilm (S. mutans - 2.21 x 105 and C. albicans - 1.06 x 107) very robust on the surface of orthodontic aligners.</p><p><strong>Conclusion: </strong>According to the results obtained, one can conclude that Invisalign® brand orthodontic aligners are susceptible to the accumulation of monospecies and mixed biofilms of S. mutans and C. albicans. Therefore, it is necessary to consider the possibility of Invisalign® users developing carious lesions associated with the biofilm formed by these two microbial species, and to guide the patient on the correct cleaning of the device during treatment.</p>","PeriodicalId":38720,"journal":{"name":"Dental Press Journal of Orthodontics","volume":"30 2","pages":"e2524192"},"PeriodicalIF":0.0,"publicationDate":"2025-05-30","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12133149/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144226996","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Developmental enamel defects: a must-know for orthodontic practice.","authors":"Marco Aurélio Benini Paschoal, Gabriele Andrade-Maia, Letícia Cristine-Silva, Aniely Ferreira Nogueira, Felícia Miranda, Daniela Garib","doi":"10.1590/2177-6709.30.2.e25spe2","DOIUrl":"10.1590/2177-6709.30.2.e25spe2","url":null,"abstract":"<p><strong>Introduction: </strong>Developmental Enamel Defects (DED) pose a significant challenge for clinicians, particularly orthodontists. These defects can lead to difficulties in differential diagnosis, orthodontic appliance adhesion, treatment planning, and overall patient management.</p><p><strong>Objective: </strong>The present review aims to provide orthodontists with a comprehensive understanding of DED and their implications for orthodontic treatment. A systematic literature search was conducted to identify relevant studies on DED and their orthodontic management.</p><p><strong>Results: </strong>The available evidence, primarily from laboratory-based studies, is of low to moderate quality. The most challenging DED cases involve structural loss, especially in molars severely affected by molar-incisor hypomineralization (MIH) and certain types of amelogenesis imperfecta.</p><p><strong>Conclusions: </strong>To address the limitations of current research, well-designed clinical studies are needed to investigate various aspects of DED management, including pre-treatment of affected enamel, adhesive techniques for bracket bonding and removal, extraction of molars affected by MIH, and interdisciplinary collaboration among dental specialists. By advancing the understanding of DED and refining treatment strategies, orthodontists can improve the outcomes for patients with these conditions.</p>","PeriodicalId":38720,"journal":{"name":"Dental Press Journal of Orthodontics","volume":"30 2","pages":"e25spe2"},"PeriodicalIF":0.0,"publicationDate":"2025-05-30","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12133151/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144226995","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Cleaning solutions for orthodontic clear aligners: a microbiological and colorimetric analysis.","authors":"Paula Cristina Henriques da Silva, Beatriz Ribeiro Ribas, Tony Vieira Faria, Janaína Habib Jorge, Luiz Gonzaga Gandini, Ary Dos Santos-Pinto, João Roberto Gonçalves, Jonas Bianchi","doi":"10.1590/2177-6709.30.2.e2524262.oar","DOIUrl":"10.1590/2177-6709.30.2.e2524262.oar","url":null,"abstract":"<p><strong>Objective: </strong>This in-vitro study aimed to evaluate the antibacterial efficacy and color changes induced by different chemical agents on the orthodontic aligners.</p><p><strong>Methods: </strong>The sample consisted of Invisalign® aligners materials and seven solutions were tested: sodium hypochlorite (HYP), sodium bicarbonate (BIC), neutral detergent (DET), chlorhexidine gluconate (CX), white vinegar (VIN) diluted in water (1:3), Corega Tabs® effervescent tablets (COR), and distilled water (DW, control group). The microbiological control was evaluated by analyzing cell proliferation (CFU/ml) and cell metabolism (AlamarBlue® test), and the VITA EasyShade® Advance spectrophotometer was used for color change analysis, using multiple Mann-Whitney tests.</p><p><strong>Results: </strong>All solutions significantly reduced S. mutans biofilm (CFU/mL), except for the control group. The AlamarBlue® analysis showed a significant reduction in cell viability, except for the BIC solution (p=0.183). After 7 days, HYP showed significant color variation, compared to all the other solutions, except for the control group (p=0.095). After 14 days, BIC and CX showed significantly greater color variation than the control group (p=0.007). DET showed a large difference compared to BIC and CX (p=0.007), and a statistically significant difference compared to VIN and COR (p=0.015).</p><p><strong>Conclusion: </strong>The disinfectant solutions HYP, DET, CX, VIN, and COR significantly reduced the bacterial colonies of S. mutans and cellular metabolism. In addition, HYP, BIC, CX, and COR significantly affected the material color.</p>","PeriodicalId":38720,"journal":{"name":"Dental Press Journal of Orthodontics","volume":"30 2","pages":"e2524262"},"PeriodicalIF":0.0,"publicationDate":"2025-05-30","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12133152/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144226994","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Impact of parental oral health literacy on orthodontic treatment need in schoolchildren.","authors":"Gélica Lima Granja, Larissa Chaves Morais de Lima, Tiago Ribeiro Leal, Veruska Medeiros Martins Bernardino, Érick Tássio Barbosa Neves, Saul Martins Paiva, Ana Flávia Granville-Garcia","doi":"10.1590/2177-6709.30.2.e2524238.oar","DOIUrl":"10.1590/2177-6709.30.2.e2524238.oar","url":null,"abstract":"<p><strong>Introduction: </strong>Malocclusion is a global health problem and when not treated in childhood, can persist throughout one's lifetime.</p><p><strong>Objective: </strong>As children are dependent on their parents/caregivers for health care, the aim of the present study was to investigate the association between parental oral health literacy and orthodontic treatment need in schoolchildren.</p><p><strong>Methods: </strong>A descriptive, analytical, cross-sectional study with a representative sample of children eight to ten years of age was conducted. Sociodemographic questionnaire, the Sleep Disturbance Scale for Children and the Oral Health Literacy - Adult Questionnaire were sent for parents/caregivers. Children answered the Revised Children's Manifest Anxiety Scale. For the diagnosis of orthodontic treatment need, the Dental Aesthetic Index was used. Data analysis included multinomial logistic regression analyses (OR) (p < 0.05).</p><p><strong>Results: </strong>Treatment need was identified for 55.2% of participants. Children with anxiety were 53% more likely to have mandatory treatment needs (OR = 1.53; 95% CI: 1.16-2.57; p = 0.04), children with sleep disturbances were 1.94 times more likely to have mandatory treatment needs (OR = 1.94; 95% CI: 1.29-2.91; p = 0.01). Children whose parents/caregivers had an insufficient level of oral health literacy were 77% more likely to have mandatory treatment needs (OR = 1.77; 95% CI: 1.04-2.99; p = 0.03).</p><p><strong>Conclusions: </strong>Orthodontic treatment need was greater among schoolchildren from families with a lower income, who lived in homes with more than five residents, whose mothers were younger, whose parents/caregivers had an insufficient level of oral health literacy, and those with sleep disorders and with anxiety.</p>","PeriodicalId":38720,"journal":{"name":"Dental Press Journal of Orthodontics","volume":"30 2","pages":"e2524238"},"PeriodicalIF":0.0,"publicationDate":"2025-05-23","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12101834/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144175181","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Comparative evaluation of bonding failure rate with two light cure orthodontic adhesives: a cross-arch split-mouth prospective study.","authors":"Dhruv Jain, Sukhbir Singh Chopra, Vivek Kumar Thakur, Surendra Kumar Sewda","doi":"10.1590/2177-6709.30.2.e2524214.oar","DOIUrl":"10.1590/2177-6709.30.2.e2524214.oar","url":null,"abstract":"<p><strong>Introduction: </strong>Continuous improvements in the field of adhesive dentistry have led to the introduction of various materials that have the potential to be used as orthodontic adhesives. One such light-cure orthodontic adhesive is the U-Bond™ Ortho, which clinically exhibits optimum bonding strength.</p><p><strong>Objective: </strong>The aim of this cross-arch split-mouth prospective study was to evaluate the bonding failure rate along with the bracket survival time of U-Bond™ Ortho as compared with Transbond™ XT adhesive material, over an observation period of six months.</p><p><strong>Material and methods: </strong>36 consecutive patients (16 males and 20 females; mean age 22.44 years) fulfilling the selection criteria were included in the study. A total of 720 brackets were bonded equally using Transbond™ XT and U-Bond™ adhesive, which were analyzed for bracket failure rate, using the Chi-square test or Fischer test, and mean bracket survival time using Kaplan-Meier analysis.</p><p><strong>Results: </strong>The overall bracket failure rate was 3.6% (2.8% and 4.4% for Transbond™ XT and U-Bond™ respectively). The results were statistically non-significant when both adhesive materials were compared for differences in bonding failure rate and mean bracket survival time in the maxillary and mandibular arches, and anterior and posterior segments, although gender-based differences were statistically significant.</p><p><strong>Conclusion: </strong>Both Transbond™ XT and U-Bond™ Ortho exhibited similar clinically acceptable performances in terms of bonding failure rate and bracket survival time.</p>","PeriodicalId":38720,"journal":{"name":"Dental Press Journal of Orthodontics","volume":"30 2","pages":"e2524214"},"PeriodicalIF":0.0,"publicationDate":"2025-05-23","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12101833/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144175122","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Does the need for refinement sets of orthodontic clear aligners correlate with professional experience?","authors":"Victor de Miranda Ladewig, Kamila de Oliveira Novais Machado, Thaís Maria Freire Fernandes, Renata Rodrigues de Almeida-Pedrin, Paula Vanessa Pedron Oltramari, Márcio Rodrigues de Almeida, Ana Cláudia de Castro Ferreira Conti","doi":"10.1590/2177-6709.30.2.e2524248.oar","DOIUrl":"10.1590/2177-6709.30.2.e2524248.oar","url":null,"abstract":"<p><strong>Objective: </strong>To assess how often orthodontists request additional aligners and correlate this need with professional's experience.</p><p><strong>Methods: </strong>A questionnaire was sent by instant messaging app (WhatsApp) to 188 orthodontists who answered it voluntarily. Respondents were grouped by experience, including time of orthodontic training (OT), training with aligners (TA) and number of cases treated with aligners (TC). They were also surveyed about the cases in which they recommend aligners. Chi-square tests were used to analyze associations between experience categories and the need for 1 or 2+ refinements, with a significance level set at 5%.</p><p><strong>Results: </strong>At least one refinement was requested in 70.31% of cases. More experienced specialists and those with longer use of aligners requested refinements more often. A second refinement was required in 21.95% of cases, primarily requested by professionals with less experience as specialists and fewer cases treated with aligners. Mild and moderate crowding were the most indicated malocclusions, while extractions and presurgical treatments were the least.</p><p><strong>Conclusion: </strong>Refinements were needed in most cases treated with aligners. Its need is not related to the lack of experience or knowledge of the technique, being mostly requested by more experienced professionals.</p>","PeriodicalId":38720,"journal":{"name":"Dental Press Journal of Orthodontics","volume":"30 2","pages":"e2524248"},"PeriodicalIF":0.0,"publicationDate":"2025-05-23","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12101830/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144175179","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Comparative evaluation of the efficiency of segmental maxillary canine retraction using Burstone T-loops versus elastomeric chains: a split-mouth randomized clinical trial.","authors":"Mohammed Abd-Elaziz Abd-Elaziz Younes, Nehal Fouad Albelasy, Ahmed Maher Fouda","doi":"10.1590/2177-6709.30.2.e2524233.oar","DOIUrl":"10.1590/2177-6709.30.2.e2524233.oar","url":null,"abstract":"<p><strong>Objective: </strong>The aim of this study was to evaluate and compare the effectiveness of elastomeric power chains and T-loop springs in retracting the maxillary canine with a time frame of four months.</p><p><strong>Material and methods: </strong>The study included 16 patients (8 women and 8 men), with a mean age of 19.06±2.22 years. These patients were recommended to bilateral maxillary first premolars extraction. A split-mouth design was used to randomly assign opposing quadrants to either power chains or T-loops. Study models and panoramic radiographs were acquired before and after canines retraction. The rate of canine retraction, rotation, tipping (primary outcome), and molar anchorage loss (secondary outcome) were measured using study models and panoramic radiograph, after retraction. All data was subjected to appropriate statistical analysis.</p><p><strong>Results: </strong>The average retraction for T-loops was 4.76 ± 1.02 mm, while for power chains it was 4.28 ± 0.81 mm. T-loops showed faster canine retraction (1.19 ± 0.08 mm/month) than power chains (1.07 ± 0.06 mm/month). T-loops had a significantly higher canine rotation (17.28±2.62°) than power chains (10.62±4.15°) (p<0.005). The sliding side showed greater tipping than the loop side, with statistically significant difference. Anchorage loss was not statistically different between both mechanics.</p><p><strong>Conclusion: </strong>T-loops offered the highest degree of canine retraction with minimal tipping, while power chains used for sectional canine retraction resulted in less canine rotation. However, there was no significant difference in the amount of anchorage loss between both mechanics.</p>","PeriodicalId":38720,"journal":{"name":"Dental Press Journal of Orthodontics","volume":"30 2","pages":"e2524233"},"PeriodicalIF":0.0,"publicationDate":"2025-05-23","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12101828/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144175175","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Cone-beam computed tomography prescription by Brazilian orthodontists.","authors":"Karine Evangelista, Grasielle Di Manoel Caiado, Maria do Carmo Matias Freire, José Valladares-Neto, Maria Alves Garcia Silva","doi":"10.1590/2177-6709.30.2.e252486.oar","DOIUrl":"10.1590/2177-6709.30.2.e252486.oar","url":null,"abstract":"<p><strong>Objective: </strong>To investigate the factors that influence Cone-beam computed tomography (CBCT) imaging prescription in Brazilian orthodontics practice.</p><p><strong>Methods: </strong>This cross-sectional study was performed in 2020 using an online survey sent to all Brazilian orthodontists registered at the Federal Council of Dentistry. The variables were the orthodontists' demographic features and the CBCT prescription in clinical practice. A descriptive and comparative analysis was implemented using frequencies and the chi-square test, respectively.</p><p><strong>Results: </strong>The sample consisted of 939 respondents. CBCT prescription and the use of guidelines for imaging in orthodontics were confirmed by 81.9% and 52.6% of the sample, respectively. Training for CBCT was reported by 37.0%, mainly during specialization programs in orthodontics (50.0%), about one to five years ago (64.7%), with a duration of 4 to 8 hours (53.4%). The CBCT prescription was indicated predominantly for specific cases (71.0%), and was generally related to impacted teeth (74.7%), orthognathic surgical patients (46.2%), and root resorption (41.9%). The results indicated differences in CBCT prescription between the Brazilian macro-regions, regarding the criteria for prescription, use of guidelines, reasons for not recommending the exam, diagnostic purposes, voxel size, and training for the use of CBCT (p<0.05).</p><p><strong>Conclusion: </strong>The prescription of CBCT was adequate by most Brazilian orthodontists for cases involving impacted teeth, surgical interventions, and root resorption. However, adherence to imaging prescription guidelines was observed in less than 50% of the sample. There is a deficiency in understanding technical parameters and a lack of specific training on CBCT. Disparities were evident among the Brazilian macro-regions, particularly concerning CBCT costs and other variables analyzed.</p>","PeriodicalId":38720,"journal":{"name":"Dental Press Journal of Orthodontics","volume":"30 2","pages":"e252486"},"PeriodicalIF":0.0,"publicationDate":"2025-05-23","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12101827/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144175177","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Oral health-related quality of life and pain perception among adult patients treated with clear aligners: a longitudinal prospective study.","authors":"Sonia Patricia Plaza-Ruíz, Judith Patricia Barrera-Chaparro, Alejandra Echeverría-Zarama, Melissa Paola Rojas-Román, Keila Stefania Susa-Valencia","doi":"10.1590/2177-6709.30.2.e2524169.oar","DOIUrl":"10.1590/2177-6709.30.2.e2524169.oar","url":null,"abstract":"<p><strong>Objective: </strong>To compare the impact on Oral Health Related Quality of Life (OHRQoL) and pain perception between adult patients undergoing fixed conventional bracket treatment (FCBT) and those undergoing clear aligner treatment (CAT) during the first three months of orthodontic treatment (OT).</p><p><strong>Method: </strong>OHRQoL was measured by the Oral Health Impact Profile (OHIP-S14 Ortho), pain perception was evaluated by the visual analog scale (VAS). The on-line questionnaires were administered immediately before OT (T0), 24-48 hours (T1), one month (T2), and three months (T3) after appliance installation. Group 1 (n = 48; 31.21 ± 11.47 years) was comprised of patients with FCBT from an orthodontic program. Group 2 (n=44; 38.30 ± 11.91 years) was comprised of patients with CAT from a private office. Chi-squared, Mann-Whitney U and Friedman tests were used for analysis.</p><p><strong>Results: </strong>In the comparison between the groups, a statistically significant difference was observed at T0, with the CAT group showing higher OHIP-S14 Ortho scores than the FCBT group (P=0.0237). However, no significant differences were found at T1, T2, or T3. OHIP-S14 Ortho scores in the FCBT group increased significantly (P<0.05) at T1-T0 and T3-T0, while CAT scores decreased. However, this trend reversed at T2-T1. Pain perceptions were lower in the CAT group at T0, T1, and T3 and at T2-T1 (P<0.01).</p><p><strong>Conclusions: </strong>In the early stages of OT, the CAT group demonstrated improvements in QoL compared to baseline, while the FCBT group showed a decrease. The negative impact on OHRQoL and pain perception over the three months of follow-up tended to decrease after 24-48 hours in both the FCBT and CAT groups. Pain perception was more negatively affected in FCBT than in the CAT group.</p>","PeriodicalId":38720,"journal":{"name":"Dental Press Journal of Orthodontics","volume":"30 2","pages":"e2524169"},"PeriodicalIF":0.0,"publicationDate":"2025-05-23","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12101829/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144175183","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Comparative evaluation of antimicrobial properties of silver nanoparticles and chlorhexidine mouthwashes on the colonization of microflora and oral health during orthodontic treatment: a double-blind randomized controlled trial.","authors":"Pradeep Raghav, Amit Kumar Khera, Shrestha Bisht","doi":"10.1590/2177-6709.30.1.e2524112.oar","DOIUrl":"10.1590/2177-6709.30.1.e2524112.oar","url":null,"abstract":"<p><strong>Introduction: </strong>Fixed orthodontic appliances facilitate microbial adhesion and plaque accumulation. Although chlorhexidine has proven to be the most effective antiplaque and antigingivitis agent, it has several side effects.</p><p><strong>Objective: </strong>The present study aims to evaluate and compare the effectiveness of silver nanoparticles (SNP) and Chlorhexidine (CHX) mouthwash on reducing the microbial count and improving oral health during fixed orthodontic treatment.</p><p><strong>Trial design: </strong>4-arm parallel, placebo-controlled, double-blind randomized clinical trial with an allocation ratio of 1:1:1:1.</p><p><strong>Methods: </strong>Microbial count of Streptococcus spp., Plaque Index, Gingival Index, Gingival Bleeding Index and Pocket Probing Depth were evaluated in 80 orthodontic patients at T0 (Pretreatment), T1 (four weeks after bonding) and T2 (four weeks after mouthwash prescription). Then patients were randomized into four groups: G1) NanOlife (containing SNP), G2) Chlorhex (containing 0.2% chlorhexidine), G3) Placebo, and G4) negative control (no mouthwash prescription) (n=20 each group). The effects of orthodontic treatment and mouthwashes were analyzed statistically.</p><p><strong>Results: </strong>The microbial count and all the four indices increased between T0 and T1 (P<0.05). They decreased below the baseline levels in Gp2, and back to baseline levels in Gp1 at T2 (P<0.05), except Gingival Bleeding index and Pocket Probing Depth. Both mouthwashes showed significantly improved therapeutic effects compared to placebo and negative control.</p><p><strong>Conclusions: </strong>Although SNP mouthwash was effective in the reduction of all the assessed parameters, it could not decrease them to the baseline levels, suggesting its limited efficacy. CHX mouthwash proved to be extremely effective by decreasing the microbial count, plaque index and gingival index below the baseline level.</p>","PeriodicalId":38720,"journal":{"name":"Dental Press Journal of Orthodontics","volume":"30 1","pages":"e2524112"},"PeriodicalIF":0.0,"publicationDate":"2025-04-07","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11980642/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143804052","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}