Romanian Journal of Diabetes, Nutrition and Metabolic Diseases最新文献_第2页

Red Blood Cells Aggregation in the Patients with Type 2 Diabetes and T2D Associated Anemia, a Case Control Study in Bangladesh 孟加拉国2型糖尿病和T2D相关贫血患者红细胞聚集的病例对照研究

Romanian Journal of Diabetes, Nutrition and Metabolic Diseases Pub Date : 2019-12-01 DOI: 10.2478/rjdnmd-2019-0044

Amirul Kabir, Gowranga Kumar Paul, K. K. Kibria

{"title":"Red Blood Cells Aggregation in the Patients with Type 2 Diabetes and T2D Associated Anemia, a Case Control Study in Bangladesh","authors":"Amirul Kabir, Gowranga Kumar Paul, K. K. Kibria","doi":"10.2478/rjdnmd-2019-0044","DOIUrl":"https://doi.org/10.2478/rjdnmd-2019-0044","url":null,"abstract":"Abstract Background and Aims: Type 2 Diabetes (T2D) is a chronic metabolic disorder. Nowadays the number of people with diabetes mellitus is quadrupling in the world as well as in Bangladesh. It is related to different types of disease morbidity and sociodemographic parameters. The present study aimed to investigate the association of RBC aggregation (measured by ESR level) with T2D and T2D associated anemia. Material and method: A total of 234 subjects were included in the study. Sociodemographic and anthropometric information about study subjects were collected using a standard questionnaire. Blood samples were tested for random blood glucose levels, Hb percentage, and ESR. Association of these data with metabolic disorders was analyzed by statistical analysis software, SPSS. Results: This study provides a piece of evidence that anemia is highly prevalent in T2D patients than the healthy control subjects in Bangladesh (59.1% vs 22.5%; P value <0.001). The ESR values were significantly elevated in T2D patients as well as anemic and aged subjects (P value <0.001). Conclusion: The study thus suggests that anemia was prevalent in T2D patients in Bangladesh. The RBC aggregation was significantly elevated in patients with T2D as well as anemia, indicating increased inflammatory response in these diseases.","PeriodicalId":38700,"journal":{"name":"Romanian Journal of Diabetes, Nutrition and Metabolic Diseases","volume":"26 1","pages":"413 - 423"},"PeriodicalIF":0.0,"publicationDate":"2019-12-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"49452334","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Effect of Health Coaching Approach Based on Motivational Interview on Improving Undesirable Nutritional Habits of Housewives 基于动机访谈的健康辅导方法对改善家庭主妇不良营养习惯的效果

Romanian Journal of Diabetes, Nutrition and Metabolic Diseases Pub Date : 2019-12-01 DOI: 10.2478/rjdnmd-2019-0037

Esmat Abdolahpour

{"title":"Effect of Health Coaching Approach Based on Motivational Interview on Improving Undesirable Nutritional Habits of Housewives","authors":"Esmat Abdolahpour","doi":"10.2478/rjdnmd-2019-0037","DOIUrl":"https://doi.org/10.2478/rjdnmd-2019-0037","url":null,"abstract":"Abstract Background and aims: Nutrition disorders are a common risk factor for many clinical disorders, and effective methods for resolving it are motivational interviewing methods that can be useful in encouraging people to promote lifestyle. In recent years, motivational interviews have come up with community health and often people in need of a change in nutritional habits are so vast that they can maintain their health. Material and method: This interventional study was carried out on all housewives referring to Mazdak Health home. They were selected by simple sampling method. The sample size was 35 in each subgroup. Food intake was assessed by a feed frequency questionnaire (FFQ) and the energy consumption in kilocalories per day was calculated using Nutritionist 4 software. Using SPSS18 and Chi-square tests, the exact test Fisher, T and Independent Tests, Mann-Whitney, and Wilcoxon were analyzed. Results: The mean score of healthy nutrition index after intervention was significantly different in intervention and control groups (p-value = 0.004). Also, in whole grain (p-value = 0.001), dairy (p-value = 0.01) Fruits (p-value = 0.01), vegetables (p-value = 0.003) had a significant difference between the mean of intervention and control groups after intervention. There were no significant differences between the other indices after the intervention in the intervention and control groups. Conclusions: The intervention has been effective and generally increases the index of healthy nutrition index after intervention. But on components of dairy, sodium, refined grains, absent calories, proteins have not had any effect.","PeriodicalId":38700,"journal":{"name":"Romanian Journal of Diabetes, Nutrition and Metabolic Diseases","volume":"26 1","pages":"345 - 352"},"PeriodicalIF":0.0,"publicationDate":"2019-12-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"47597123","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Comparison of Efficacy of Nortriptyline Versus Transcutaneous Electrical Nerve Stimulation on Painful Peripheral Neuropathy in Patients with Diabetes 去甲替林与经皮神经电刺激治疗糖尿病患者疼痛性周围神经病变的疗效比较

Romanian Journal of Diabetes, Nutrition and Metabolic Diseases Pub Date : 2019-12-01 DOI: 10.2478/rjdnmd-2019-0043

Mehrnoosh Zakerkish, Davood Raeisi, Shahram Rafie, M. Yazdi, Zahra Kosarian, Shirin Rahimzadeh Telegrafchi, Saeed Hesam

{"title":"Comparison of Efficacy of Nortriptyline Versus Transcutaneous Electrical Nerve Stimulation on Painful Peripheral Neuropathy in Patients with Diabetes","authors":"Mehrnoosh Zakerkish, Davood Raeisi, Shahram Rafie, M. Yazdi, Zahra Kosarian, Shirin Rahimzadeh Telegrafchi, Saeed Hesam","doi":"10.2478/rjdnmd-2019-0043","DOIUrl":"https://doi.org/10.2478/rjdnmd-2019-0043","url":null,"abstract":"Abstract Background and aims: Diabetic peripheral neuropathic pain (DPNP) is one of the most common complications of diabetes and is difficult to treat. Existing treatments are often inadequate at controlling pain and limited by side-effects and drug tolerance. This study assessed the efficacy of nortriptyline versus Transcutaneous Electrical Nerve Stimulation (TENS) in patients with DPNP. Material and method: This is a randomized clinical trial study conducted on 39 patients with DPNP referring to Golestan Hospital in Ahvaz in 2017. Patients were randomly treated with TENS (18 sessions, each session 30 minutes; n=20) or nortriptyline (25 to 75 mg, once daily; n=19) for 6 weeks. Patients were evaluated for side effects and pain relief using visual analog scale (VAS). Results: There was a significant improvement in pain with both treatments compared with baseline (p˂0.001). The patients in nortriptyline group experienced more pain relief (7.21±1.51 to 0.84±1.34) than the TENS group (7.6±1.47 to 2.75 ±2.43) (P=0.001). The 50% pain relief was observed in 14 patients (73%) in nortriptyline group, 6 patients (30%) in TENS group. Moreover, the side effects were seen in 15% of TENS and 55% of patients in nortriptyline groups (P=0.019). Conclusion: Both TENS and nortriptyline were effective and safe in the management of DPNP. But nortriptyline showed a better performance on pain relief.","PeriodicalId":38700,"journal":{"name":"Romanian Journal of Diabetes, Nutrition and Metabolic Diseases","volume":"26 1","pages":"401 - 411"},"PeriodicalIF":0.0,"publicationDate":"2019-12-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"44466372","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 4

Hypoglycemia and the Risk of Cardiovascular Events: Causality or (Just) an Epidemiological Association?! 低血糖与心血管事件的风险：因果关系还是（仅仅）流行病学关联？！

Romanian Journal of Diabetes, Nutrition and Metabolic Diseases Pub Date : 2019-12-01 DOI: 10.2478/rjdnmd-2019-0036

C. Bala

{"title":"Hypoglycemia and the Risk of Cardiovascular Events: Causality or (Just) an Epidemiological Association?!","authors":"C. Bala","doi":"10.2478/rjdnmd-2019-0036","DOIUrl":"https://doi.org/10.2478/rjdnmd-2019-0036","url":null,"abstract":"Since the early termination of the Action to Control Cardiovascular Risk in Diabetes (ACCORD) trial in 2008 due to higher mortality in the intensive glucose arm, the relationship between hypoglycemia, mainly severe hypoglycemic episodes (SHE), and negative outcomes (with focus on cardiovascular [CV] events and mortality, and all-cause mortality) started to be more carefully scrutinized by scientific researchers and avoidance of hypoglycemia has been included in all diabetes guidelines among the targets set for the management of hyperglycemia. Numerous randomized clinical trials and epidemiological studies found a robust association between SHE and incident major CV events and mortality, as well as all-cause deaths but this association was not found for non-severe hypoglycemia. Two recent reports suggest that a “frail” T2D phenotype, characterized by older age, longer diabetes duration, lower glomerular filtration rate, who were more frequently non-White, insulin treated, and had prior CV or heart failure events, increased susceptibility to both SHEs and CV events and that SHEs do not cause deleterious CV outcomes. Nevertheless, other researchers claim that the causality exists between SHEs and increased risk for subsequent CV events and mortality. Avoidance of hypoglycemia remains a target of antihyperglycemic strategies while efforts to attain and maintain individualized glucose targets should be done from the time of diagnosis and throughout all diabetes duration.","PeriodicalId":38700,"journal":{"name":"Romanian Journal of Diabetes, Nutrition and Metabolic Diseases","volume":"26 1","pages":"341 - 344"},"PeriodicalIF":0.0,"publicationDate":"2019-12-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"49437017","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Beneficial Effect of Pachyrhizus erosus Fiber as a Supplemental Diet to Counteract High Sugar-Induced Fatty Liver Disease in Mice 绿脓杆菌纤维作为补充日粮对抗高糖诱导的小鼠脂肪肝的有益作用

Romanian Journal of Diabetes, Nutrition and Metabolic Diseases Pub Date : 2019-12-01 DOI: 10.2478/rjdnmd-2019-0038

P. Santoso, R. Maliza, Q. Fadhilah, S. J. Insani

{"title":"Beneficial Effect of Pachyrhizus erosus Fiber as a Supplemental Diet to Counteract High Sugar-Induced Fatty Liver Disease in Mice","authors":"P. Santoso, R. Maliza, Q. Fadhilah, S. J. Insani","doi":"10.2478/rjdnmd-2019-0038","DOIUrl":"https://doi.org/10.2478/rjdnmd-2019-0038","url":null,"abstract":"Abstract Background and aims: Edible fiber isolated from the tuber of yam bean (Pachyrhizus erosus, Leguminosae) has been suggested to prevent the development of metabolic diseases caused by excessively consuming sugary foods. However, it is unclarified whether P. erosus fiber (PEF) is also capable of preventing liver diseases. This study aimed to determine the effectivity of PEF in counteracting the development of non-alcoholic fatty liver disease (NAFLD) caused by excessive intake of high-sugar diet (HSD). Material and method: 25% of PEF in HSD (w/w) was fed in BALB/c mice for eight weeks followed by subsequent morphological and histological examinations of the liver at the end of treatment in comparing with HSD alone. Results: We found that supplementation of 25% PEF sustained the normal morphological feature of the liver in HSD-fed mice. Moreover, PEF also prevented the development of microvesicles in the liver tissue, nuclear shrinkage, and hepatolysis as indicators of liver disease. Macrophages infiltration as a marker of liver inflammation was also less observed in PEF-treated mice. Conclusions: PEF could effectively elicit a beneficial effect against NAFLD caused by HSD. Hence, PEF is suggested to be used as a potent supplemental diet to preclude the metabolic diseases caused by HSD.","PeriodicalId":38700,"journal":{"name":"Romanian Journal of Diabetes, Nutrition and Metabolic Diseases","volume":"26 1","pages":"353 - 360"},"PeriodicalIF":0.0,"publicationDate":"2019-12-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"49343072","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 3

Micronutrients and Oral Health an Opportunity to Prevent Oral Diseases 微量营养素与口腔健康——预防口腔疾病的机会

Romanian Journal of Diabetes, Nutrition and Metabolic Diseases Pub Date : 2019-09-01 DOI: 10.2478/rjdnmd-2019-0032

P. Shetty, A. Shetty, S. Kumari

引用次数: 1

Complexity of Cardiac Autonomic Modulation in Diabetes Mellitus: A New Technique to Perceive Autonomic Dysfunction 糖尿病患者心脏自主神经调节的复杂性:一种感知自主神经功能障碍的新技术

Romanian Journal of Diabetes, Nutrition and Metabolic Diseases Pub Date : 2019-09-01 DOI: 10.2478/rjdnmd-2019-0029

D. Garner, Naiara Maria de Souza, V. Valenti, L. Vanderlei

引用次数: 0

The Effect of Thymoquinone Toward Tooth Disorder Prevention in Postnatal Rat offspring Born from Hyperglycemia Pregnant Rats 百里醌对高血糖妊娠大鼠胎鼠牙障碍的预防作用

Romanian Journal of Diabetes, Nutrition and Metabolic Diseases Pub Date : 2019-09-01 DOI: 10.2478/rjdnmd-2019-0025

S. N. Rachmawati, Nuzulul Hikmah, T. Indriana, Mei Syafriadi

{"title":"The Effect of Thymoquinone Toward Tooth Disorder Prevention in Postnatal Rat offspring Born from Hyperglycemia Pregnant Rats","authors":"S. N. Rachmawati, Nuzulul Hikmah, T. Indriana, Mei Syafriadi","doi":"10.2478/rjdnmd-2019-0025","DOIUrl":"https://doi.org/10.2478/rjdnmd-2019-0025","url":null,"abstract":"Abstract Background and aims. Hyperglycemia in pregnancy was caused by reduced insulin production that led to tooth germ growth disorder. Thymoquinone could increase insulin production through pancreatic β-cells regeneration. The purpose of this study was to determine the effect of thymoquinone to prevent tooth disorder in rat offspring born from hyperglycemia pregnant rat. Material and method. Wistar rat offspring used in this research taken from pregnant rat induced hyperglycemia with streptozotocin 40 mg/kgBW divided into four groups. Rat offspring observation had been done on 3rd, 5th, and 7th day postnatal. The histological image of first maxillary molar tooth germ stained with Haematoxilin Eosin and Mallory’s Trichrome. The parameters of rat offspring were body weight, blood glucose levels, tooth growth stages, tooth dimension width, and tooth germ enamel matrix. Results. Thymoquinone group had the widest tooth germ dimension compare to other groups. All rat offspring tooth germs were at the appositioncalcification stage in matrix enamel (pre-enamel). The analysis showed that no statistical differences between thymoquinone group and metformin group (p>0.05). Conclusions. Thymoquinone has same function with metformin to prevent tooth disorder in rat offspring born from pregnant rat induced hyperglycemia.","PeriodicalId":38700,"journal":{"name":"Romanian Journal of Diabetes, Nutrition and Metabolic Diseases","volume":"26 1","pages":"243 - 252"},"PeriodicalIF":0.0,"publicationDate":"2019-09-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"44681160","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 1

Early Renal Dysfunction in Obese Patients with Insulin Resistance 胰岛素抵抗的肥胖患者早期肾功能异常

Romanian Journal of Diabetes, Nutrition and Metabolic Diseases Pub Date : 2019-09-01 DOI: 10.2478/rjdnmd-2019-0027

N. Pertseva, M. Rokutova

引用次数: 0

Euglycemic Ketoacidosis Diagnosis and Treatment Protocol in Type 1 Diabetes Patient 1型糖尿病正糖酮症酸中毒的诊断与治疗方案

Romanian Journal of Diabetes, Nutrition and Metabolic Diseases Pub Date : 2019-09-01 DOI: 10.2478/rjdnmd-2019-0034

A. Dumitru, M. Posea

{"title":"Euglycemic Ketoacidosis Diagnosis and Treatment Protocol in Type 1 Diabetes Patient","authors":"A. Dumitru, M. Posea","doi":"10.2478/rjdnmd-2019-0034","DOIUrl":"https://doi.org/10.2478/rjdnmd-2019-0034","url":null,"abstract":"Abstract Introduction. The introduction of sodium glucose cotransporter 2 inhibitors in the management of diabetes was an innovation in the treatment of this disease, considering the protective cardiovascular effect not only the ability of decreasing the plasma glucose. In Europe, this class of medication is approved for the treatment of type 2 diabetes and some of them (dapagliflozin and sotagliflozin) are also approved for use in certain patients with type 1 diabetes mellitus. These patients must have inadequate control of their blood glucose levels despite optimal insulin therapy. One of the adverse effects is diabetic ketoacidosis. Case report. This case report presents a diabetic patient whose treatment was changed from insulin therapy to oral therapy. Within 10 days after the initiation of the new treatment her condition gradually worsened and she arrived at the emergency room with nausea, vomiting and altered general condition. She was admitted for euglycemic ketoacidosis and treated according to the protocol. Conclusions. This case reveals the importance of continuing the insulin therapy when adding a sodium glucose cotransporter 2 inhibitor in type 1 diabetes patients.","PeriodicalId":38700,"journal":{"name":"Romanian Journal of Diabetes, Nutrition and Metabolic Diseases","volume":"26 1","pages":"323 - 326"},"PeriodicalIF":0.0,"publicationDate":"2019-09-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"44280384","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0