International Journal of Science, Technology & Management最新文献

{"title":"Phytochemical Screening And Test For Reducing Uric Acid Levels In Male Rats After Administration Of Ethanol Extract Of The Herb Binara (Artemisia vulgaris L.)","authors":"Novidawati Boru Situmorang, U. Harahap, P. Hasibuan","doi":"10.46729/ijstm.v4i4.868","DOIUrl":"https://doi.org/10.46729/ijstm.v4i4.868","url":null,"abstract":"Hyperuricemia is a metabolic disease generally characterized by high uric acid levels in the blood. The general treatment strategy for hyperuricemia is to decrease uric acid production using xanthine oxidation reductase inhibitors such as allopurinol and uricosuric agents. However, the drugs showed side effects, including skin rashes, diarrhoea and liver damage. To overcome the side effects of synthetic drugs, alternatives are used, namely by researching to find plants that have activity in reducing uric acid levels. The activity of reducing uric acid levels in plants is likely due to the presence of flavonoid compounds as antioxidants. Flavonoids active in reducing uric acid levels are kaempferol through xanthine oxidase inhibitors. Quercetin also has the potential to reduce uric acid levels through inhibition of the xanthine oxidase enzyme. Binara plant (Artemisia vulgaris L.) has flavonoids, tannins, alkaloids, glycosides and saponins which have potential as antioxidants and analgesics, anti-inflammatory, immunomodulating, and hepatoprotective, through secondary metabolites of flavonoids, terpenes, and phenolic acids. The Karo people have traditionally used Binara leaves to treat wounds, diarrhoea and heartburn by chewing some of the leaves and then placing them on the wounds outside the body, such as cuts and for diarrhoea and stomach ulcers and placing them around the sick stomach. This study was conducted to know the anti-hyperuricemia effect of the Ethanol Extract of Herba Binara (Artemisia vulgaris L.) on gout rats; phytochemical screening was carried out first to determine the content of Herba Binara (Artemisia vulgaris L.) compounds. The results showed that Herb Binara fulfilled the simplicia characterization requirements and contained secondary metabolites such as alkaloids, flavonoids, tannins, glycosides, saponins and steroids. Herb Binara Ethanol Extract has been shown to reduce uric acid levels in hyperuricemia rats, with the best concentrations being 400 and 800 mg/kg body weight. This was based on significantly different results p>0.05 compared to the positive control group.","PeriodicalId":384527,"journal":{"name":"International Journal of Science, Technology & Management","volume":"137 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2023-07-23","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"121239205","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Application Of The Sol-Gel Hydroxhapatite Synthesis Method From Green Clam Shell","authors":"L. Edahwati, S. Sutiyono, Aninda Ikaputri, Moh Nur Fuadzi","doi":"10.46729/ijstm.v4i4.864","DOIUrl":"https://doi.org/10.46729/ijstm.v4i4.864","url":null,"abstract":"Hydroxyapatite is the main mineral that makes up bones and teeth so that it has a level of similarity with the mineral parts of bones and can be used as an alternative bone substitute material. As an alternative material for bone substitution, hydroxyapatite has a fairly high economic value and is still dominated by imports from foreign countries. In an effort to reduce the level of imports of hydroxyapatite, research was carried out on green mussel shells as a source of calcium for the synthesis of hydroxyapatite. The synthesis of hydroxyapatite was carried out using the sol-gel method with raw materials for calcium precursors obtained from green mussel shells and varied concentrations of phosphoric acid (0.1 M, 0.5 M, 1 M; 1.5 M; and 2 M). Based on the analysis of the hydroxyapatite product produced using Atomic Absorption Spectrophotometry analysis, it was found that the ratio of Calcium-Phosphate (Ca/P) for H3PO4 concentrations was 0.1 M, 0.5 M, 1 M; 1.5M; and 2 M respectively by 1.73; 1.70; 1.67; 1.63; and 1.61. In addition, based on the results of the Fourier Transform Infra Red analysis, a random sample also found a Ca-O group; PO43; and OH- which is the main group of Hydroxyapatite and from SEM analysis the crystal morphology is known to be spherical, uneven and agglomerated so that in this study the synthesis of Hydroxyapatite using the sol-gel method was successfully carried out..","PeriodicalId":384527,"journal":{"name":"International Journal of Science, Technology & Management","volume":"47 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2023-07-23","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"123312156","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"The Impact Of Product Quality And Service Quality On Consumer Satisfaction At Kedai Falsafah Ngopi Bogor, Indonesia","authors":"Ismartaya Ismartaya, Lucky Hikmat Maulana, Wildaria Simanjuntak, T. Kartini","doi":"10.46729/ijstm.v4i4.899","DOIUrl":"https://doi.org/10.46729/ijstm.v4i4.899","url":null,"abstract":"In the current era of globalization the business world is growing day by day so companies will not be separated from competition and are required to provide a good marketing system. The problem of product quality, service quality and customer satisfaction is the determining factor so it needs to be investigated. The sampling technique used was purposive sampling with a total sample of 60. The data collection technique used a questionnaire that had been tested for validity, reliability test, and classical assumption test. The data analysis method used was multiple linear regression analysis, correlation coefficient analysis, and coefficient of determination analysis. A hypothesis test was also conducted using the F test method and the t test. The results showed that simultaneously and partially product quality, service quality had a positive and significant effect on consumer satisfaction. It is recommended to evaluate to find information that makes consumers comfortable and satisfied.","PeriodicalId":384527,"journal":{"name":"International Journal of Science, Technology & Management","volume":"126 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2023-07-23","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"116179703","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Analysis of Relation Between Risk-Based Work Breakdown Structure (WBS) on Integrated Design and Construction Works of Design and Build Contract on Mechanical and Electrical Works of High Rise Building for Improving Safety Performance","authors":"Mariana Feronica Damanik, Y. Latief, Danang Budi Nugroho","doi":"10.46729/ijstm.v4i4.860","DOIUrl":"https://doi.org/10.46729/ijstm.v4i4.860","url":null,"abstract":"The construction industry has had the highest accident rate worldwide for decades. Identifying risks as early as feasible during the pre-construction or design phase is essential to preventing construction accidents. To generate a structured list of risks, a Work Breakdown Structure (WBS) is used to identify risks. Although numerous studies have proposed using Work Breakdown Structure (WBS) to identify risks, no one has analyzed the relationship between Work Breakdown Structure (WBS) and risk to reduce construction accidents. Consequently, this study aimed to investigate the impact of Work Breakdown Structure (WBS) risk during the design and construction phases on construction safety performance. The analysis of relationships will be conducted using statistical methodologies. The study's findings will demonstrate that Work Breakdown Structure (WBS) risk affects construction safety performance.","PeriodicalId":384527,"journal":{"name":"International Journal of Science, Technology & Management","volume":"1 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2023-07-23","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"126928986","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Effect Of Seft Giving (Spiritual Emotional Freedom Technique) On The Level Of Anxiety Of Covid 19 Patients In The Edelweis Isolation,Orthopedic Hospital Prof. Dr. R. Soeharsosurakarta","authors":"Erwi Rochma, Rohman Rohman, Wahid Ansori, Ferry Aiyanto, Qowiyatul Muthmainah, Putri Dewi Suciningtyas","doi":"10.46729/ijstm.v4i4.895","DOIUrl":"https://doi.org/10.46729/ijstm.v4i4.895","url":null,"abstract":"Coronavirus Disease (covid-19) is a disease caused by the Severe AcuteRespiratory Syndrome Coronavirus-2(SARS-COV-2) virus. Coronavirus Disease(covid-19) has become a worldwide pandemic. This study aims to determine theEffect of Giving SEFT (Spiritual Emotional Freedom Technique) Regarding the Anxiety Level of Covid-19 Patients in the Edelweis Isolation Ward, Prof. Orthopedic Hospital. Dr. R. Soeharso Surakarta. Thisresearch is a quantitativestudy, with the experimental method of one group pre and post test design (withoutcontrol group), which is done to reveal causal relationships or influences by involving one group of subjects.This research was conducted on 30 respondents in the Edelweis Isolation Ward, Prof. Orthopedic Hospital. Dr. R. Soeharso Surakarta, with female sex as much as 60% and the most age range 45-55 years asmuch as 36.7%, most jobs are private as much as 20% and most education is S1 as many as 33.3%. Respondents with comorbidities were 43.3% and 23.3% were patients with pneumonia. From the results of the analysis using the Wilcoxon test, the p-value = 0.00001 (<0.05). There is an effect of giving SEFT (Spiritual EmotionalFreedom Technique) therapy on the anxiety level of Covid-19 patients in the Edelweis ward of Prof.Orthopedic Hospital. Dr. R. Soeharso Surakarta.","PeriodicalId":384527,"journal":{"name":"International Journal of Science, Technology &amp; Management","volume":"1 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2023-07-23","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"132495004","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Antibiofilm Formation Activities of Ethanol Extract of Curcuma domestica Val. Rhizome Against Multidrug-resistant Acinetobacter baumannii","authors":"Halimah Raina Nasution, Yuandani, A. Septama, S. E. Nugraha, Sufitni","doi":"10.46729/ijstm.v4i4.883","DOIUrl":"https://doi.org/10.46729/ijstm.v4i4.883","url":null,"abstract":"Abstract. \u0000  \u0000Multidrug resistance is still a major health problem worldwide. Biofilm formation was related to the resistance of bacteria mechanism. Acinetobacter baumannii, one of the bacteria that cause nosocomial infections, is given particular attention due to its high prevalence of resistance. The current study address observing the antibacterial activity and antibiofilm formation activity of Curcuma domestica rhizome extract against multidrug-resistant Acinetobacter baumannii (MDR A.baumannii). Curcuma domestica rhizome was macerated by ethanol 96%. Determination of Minimum Inhibitory Concentration (MIC) was carried out by the microdilution method. Antibiofilm formation analysis was determined by standard quantitative using crystal violet-stained assay. Ethanol extract of C. domestica possesses antibacterial activity against MDR A. baumannii with MIC value 250 µg/mL. Additionally, the ethanol extract of C. domestica could inhibit the biofilm formation of MDR A.baumannii, thus percentage of biofilm formed only 23.7% and significance different with control after analyzed using ANOVA post hoc test Tukey. According to these results, ethanol extract of C. domestica revealed antibacterial activity and had the potency in suppressing the biofilm formation of MDR A.baumannii, thus could be utilized in clinical application, especially in MDR A.baumannii infection. \u0000  \u0000Keywords: Antibiofilm, antibacterial, Curcuma domestica, multidrug-resistant, Acinetobacter baumannii \u0000  \u0000  \u0000 ","PeriodicalId":384527,"journal":{"name":"International Journal of Science, Technology &amp; Management","volume":"415 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2023-07-23","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"124164858","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"A Study of Managed Care Health System During Pandemic","authors":"Gebyar Ayu, Hari Fermansyah, Erlina Puspitaloka Mahadewi","doi":"10.46729/ijstm.v4i4.846","DOIUrl":"https://doi.org/10.46729/ijstm.v4i4.846","url":null,"abstract":"The present study reports the comprehensive study on managed care during the pandemic, regarding to the cases of the covid-19 outbreak increased every day, even reaching 2,000 cases per day in Indonesia. The surge in the cost of handling covid-19 patients and delays in payment of covid-19 claims by the Indonesian Ministry of Health have worsened the situation and the handling of the quality of services by health service providers. For this reason, the role of managed care is needed in these conditions. The purpose of this study is to analyze and find out the pattern and course of managed care in Indonesia by comparing it with several countries that have also been infected with covid-19. This research method is a literature review study with an online database search strategy or search engine in the form of related research journals from the year 2020-2023. The results obtained by researchers are the lack of health human resources, medical devices and \"pandemic fatigue\" which are problems that contribute to the course of managed care in almost every region in Indonesia. The role of society and government policies affect the overall implementation of managed care programs. When the community complies with the policies that apply in the pandemic era and the government provides policies in collaboration with health experts. Managed care program one of prospective plan for Indonesia healthcare industry development in the future.","PeriodicalId":384527,"journal":{"name":"International Journal of Science, Technology &amp; Management","volume":"27 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2023-07-23","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"124282084","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Revolutionizing Journal Publishing: Unleashing The Power Of Web-Based Chatbot Development With Dialogflow And Natural Language Processing","authors":"J. Setiawan, R. Ng","doi":"10.46729/ijstm.v4i4.893","DOIUrl":"https://doi.org/10.46729/ijstm.v4i4.893","url":null,"abstract":"The chatbot is a manifestation of Artificial Intelligence that can replace humans in engaging in conversational interactions and providing information services to users or visitors. Chatbots generally interact through text messages, voice, images, and other mediums. In this study, a web-based chatbot application was developed for a journal website called the Journal of Multidisciplinary Issues, aiming to relieve site administrators from having to repeatedly answer the same visitor questions. The development of the chatbot application followed the Rapid Application Development method, involving several stages including planning, design, system development, implementation, and testing. The application was built using Google Dialogflow services, employing Natural Language Processing techniques, along with the integration feature called Dialogflow Messenger, which offers a wide range of response options for journal websites utilizing Open Journal Systems. The chatbot application was evaluated using Alpha and Closed Beta Testing methodologies, which yielded promising results. The chatbot demonstrated the ability to provide appropriate responses after being tested with various question scenarios, achieving a score of 85.25% in the questionnaire-based assessment, which aimed to gauge visitor perspectives on the developed chatbot application. Future research endeavors should focus on integrating the chatbot with popular social media platforms such as Facebook, WhatsApp, or LINE.","PeriodicalId":384527,"journal":{"name":"International Journal of Science, Technology &amp; Management","volume":"17 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2023-07-23","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"126476591","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Development Of Risk-Based Work Breakdown Structure (WBS) Standards For Integrated Design And Construction Phase On Design-Build Method Of Architectural Works Of High-Rise Building To Improve Construction Safety Performance","authors":"Gabby Andina Ganesdhi, Y. Latief, Danang Budi Nugroho","doi":"10.46729/ijstm.v4i4.896","DOIUrl":"https://doi.org/10.46729/ijstm.v4i4.896","url":null,"abstract":"Design-build methods are one of the options in carrying out the construction of high-rise buildings with a high level of uncertainty from design phase to construction, which also affects the safety performance of the project itself. Therefore, a prevention standard for a high-risk event is needed based on project activities. This research was prepared using a descriptive qualitative method with expert validation process through Delphi method and completed with a questionnaire survey to conduct a risk assessment. The output in this research is a development of risk-based standard work breakdown structure for architectural work, which generated from 39 high level risk. Based on the results of the mapping of preventive and corrective actions at high-level risks, 5 types of WBS development can be carried out at levels 3 to 6 of the WBS to prevent and minimize the impact of risk so that safety performance could be improved. The novelty in this research lies in the form of design-build project delivery activities which has not been widely discussed in previous work breakdown structure research and risk identification based on the activities listed on the WBS.","PeriodicalId":384527,"journal":{"name":"International Journal of Science, Technology &amp; Management","volume":"13 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2023-07-23","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"129905960","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Optimization of Trigona Honey and Coating Material Formulations for Antioxidants and Physical Properties of Microencapsulation of Coriander Seed Extract Using the D-Optimal Mixture Method","authors":"Irfan Muttaqin, Y. Taufik, Yusep Ikrawani","doi":"10.46729/ijstm.v4i4.870","DOIUrl":"https://doi.org/10.46729/ijstm.v4i4.870","url":null,"abstract":"The purpose of this study was to produce an optimal formulation of coriander seed extract microencapsulation products using the Mixture D-Optimal Design Expert program.The study consists of two stages. The first stage was the analysis of the coriander seed extract powder using the spray drying method without the use of coating materials and honey. The second stage was to determine the optimal formula using the D-Optimal Mixture method of Design Expert program through measurement of chemical responses (antioxidant activity, and water content), physical response. (particle size). The optimum formula obtained based on the Design Expert program with the D-Optimal Mixture method has a desirability value of 1 with the prediction value of each response being 395.124 ppm antioxidant activity, 2.329 % water content, and 2.967 µm particle size.","PeriodicalId":384527,"journal":{"name":"International Journal of Science, Technology &amp; Management","volume":"26 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2023-07-23","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"129382692","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}