Journal of Pharmaceutical Technology, Research and Management最新文献_第2页

Phytoconstituents in Breast Cancer Prevention 预防乳腺癌的植物成分

Journal of Pharmaceutical Technology, Research and Management Pub Date : 2022-05-07 DOI: 10.15415/jptrm.2022.101005

Shreya Sood, Sushma Devi, Thakur Gurjeet Singh, A. Kaur, Vinita Singh, Prinsi Sahpuriya

{"title":"Phytoconstituents in Breast Cancer Prevention","authors":"Shreya Sood, Sushma Devi, Thakur Gurjeet Singh, A. Kaur, Vinita Singh, Prinsi Sahpuriya","doi":"10.15415/jptrm.2022.101005","DOIUrl":"https://doi.org/10.15415/jptrm.2022.101005","url":null,"abstract":"Background: In today’s developing nations, breast cancer (BC) is among the foremost risk factor for women. The causes of mortality are still unclear, yet they are frequently related to socioeconomic level and way of life. Numerous clinical therapies have been employed up to this point, i.e., radiotherapy, hormonal treatment, targeted treatment, mastectomy, and treatment with drugs etc. Purpose: However, resistance development to chemotherapeutic drugs, radiation and hormonal therapy is one of the common problems for many of the patients with BC. Numerous studies have looked at the anti-cancer potential of natural products due to the fact that they are generally safe. Researchers’ interest is being drawn by phytochemicals from plants that are thought to be bioactive. In this review the formation and progression of breast cancer were also studied, along with the mode’s of activity and regulatory function of these phytoconstituents in major signalling networks within the cell. Conclusion: Phytoconstituents in Breast Cancer Prevention have potential future as well as the difficulties. So, need more study and instructions for experimental animals, medical research, and experimental in vitro and in vivo methods are critically evaluated.","PeriodicalId":382729,"journal":{"name":"Journal of Pharmaceutical Technology, Research and Management","volume":"177 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2022-05-07","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"116164975","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Pharmacovigilance in India: Present and Future Prospects 印度的药物警戒:现在和未来展望

Journal of Pharmaceutical Technology, Research and Management Pub Date : 2022-05-07 DOI: 10.15415/jptrm.2022.101001

T. G. Singh

引用次数: 0

Scary Truth of Medical Personnel in India 印度医务人员的可怕真相

Journal of Pharmaceutical Technology, Research and Management Pub Date : 2022-05-07 DOI: 10.15415/jptrm.2022.101009

Amit Sharma, Ian Osoro, Ruby Gangwar

引用次数: 0

A Coherent Analytical Review of Indapamide 吲达帕胺的相关分析综述

Journal of Pharmaceutical Technology, Research and Management Pub Date : 2022-05-07 DOI: 10.15415/jptrm.2022.101004

A. P. Rajput, A. P. Edlabadkar

{"title":"A Coherent Analytical Review of Indapamide","authors":"A. P. Rajput, A. P. Edlabadkar","doi":"10.15415/jptrm.2022.101004","DOIUrl":"https://doi.org/10.15415/jptrm.2022.101004","url":null,"abstract":"Background: Indapamide is a diuretic of particular importance in an antihypertensive therapeutic regime that is profoundly applied to treat hypertension. Besides using as an individual drug for its diuretic and thereby antihypertensive effect, the drug is also a part of crucial combinations with Angiotensin-Converting Enzyme inhibitors. The recent combinations of Indapamide with Perindopril and Delapril work as the best therapies for heart patients. Purpose: Considering the therapeutic and pharmaceutical importance of the drug molecule and its potential to be explored in future drug discovery and delivery, we made efforts to portray the pharmaceutical analytical profile of the drug molecule at ease. Method: The present article is a composition entailing the comparative and critical evaluation of the various analytical approaches explored for the pharmaceutical estimation ofIndapamide as a particular drug in combinations and pharmaceutical as well as biological matrices. The analyses are reviewed for the specificapplications of analytical methods tested Indapamide alone or with other medications. Result: The anticipated study revealed the comparative usage of different research techniques for Indapamide estimation. The study influences the possibility of constraints and focuses on the recent trend in Indapamide analysis. The article also provides an understanding of sample processing, drug extraction method, validation protocols/approaches, and stability studies, including but not limited to the bioanalytical perspectives. Conclusion: This review can be explored thoroughly for the future analytical and pharmaceutical insights of Indapamide to the fullest.","PeriodicalId":382729,"journal":{"name":"Journal of Pharmaceutical Technology, Research and Management","volume":"29 6","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2022-05-07","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"134555558","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Mechanistic role of herbals as alternative therapy for epilepsy 草药作为癫痫替代疗法的机制作用

Journal of Pharmaceutical Technology, Research and Management Pub Date : 2022-05-07 DOI: 10.15415/jptrm.2022.101003

Diksha Sharma, Veerta Sharma, Gaaminepreet Singh, T. G. Singh, A. Grewal

引用次数: 0

Therapeutic Implication of Herbal Phytoconstituents in Stroke 中草药植物成分对中风的治疗意义

Journal of Pharmaceutical Technology, Research and Management Pub Date : 2021-11-08 DOI: 10.15415/jptrm.2021.92006

H. Khan, Vivek Rihal, T. G. Singh, A. Grewal

{"title":"Therapeutic Implication of Herbal Phytoconstituents in Stroke","authors":"H. Khan, Vivek Rihal, T. G. Singh, A. Grewal","doi":"10.15415/jptrm.2021.92006","DOIUrl":"https://doi.org/10.15415/jptrm.2021.92006","url":null,"abstract":"Introduction: Ischemic stroke is a prominent global cause of death and disability. Other than employingischemic stroke treatment with recombinant tissue plasminogen activator, which must be administered within 3 hours of an acute incident and carries a high risk of hemorrhagic complications, there is currentlya few effective stroke treatment should be done. Herbal medicines, mainly derived from plants, are an excellent source for developing novel therapeutic agents for a wide range of human illnesses. In additionally, the multifaceted influence of herbal medicine and its active ingredients on stroke aetiology may indicate a bright future for natural medicine in stroke therapy. Objective: Herbal medications are effective in stroke therapy because of their anti apoptotic, neuroprotective, anti inflammatory, and vascular protecting effects. Although herbal remedies are often thought of as safe and effective, there is a frequent misconception that if a treatment is effective, it must have side effects. As a result, herbal remedies are either useless or have undesirable side effects as medications. A sizeable portion of the populations in many developed countries relies on traditional healers and their supply of medicinal plants to suit their medical needs. Conclusion: Even after due to historical and cultural factors, herbal medicines have typically retained their popularity despite the advent of modern medicine alongside such ancient therapies. Additionally, herbal remedies are more advantageous for chronic health issues like stroke. This review looks at the possible mechanism of Action for the Valuable Effects of Herbal Medicines in stroke patients.","PeriodicalId":382729,"journal":{"name":"Journal of Pharmaceutical Technology, Research and Management","volume":"23 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2021-11-08","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"123438828","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 2

Low Dose Aspirin as Prophylaxis Reduces the Incidence of Preeclampsia in Women at High Risk – A Review 低剂量阿司匹林预防可降低高危妇女先兆子痫的发生率

Journal of Pharmaceutical Technology, Research and Management Pub Date : 2021-11-08 DOI: 10.15415/jptrm.2021.92010

Riya M Cherian, Parminder Nain, Sanjana Mehta, S. Chauhan, Jaspreet Kaur

引用次数: 0

Therapeutic Implication of Herbal Phytoconstituents in Alzheimer’s Disease 草药成分对阿尔茨海默病的治疗意义

Journal of Pharmaceutical Technology, Research and Management Pub Date : 2021-11-08 DOI: 10.15415/jptrm.2021.92007

Vivek Rihal, H. Khan, T. G. Singh, A. Grewal

{"title":"Therapeutic Implication of Herbal Phytoconstituents in Alzheimer’s Disease","authors":"Vivek Rihal, H. Khan, T. G. Singh, A. Grewal","doi":"10.15415/jptrm.2021.92007","DOIUrl":"https://doi.org/10.15415/jptrm.2021.92007","url":null,"abstract":"Introduction: Herbal plants have been widely used in traditional medicines for improving cognitive decline and age-related loss of memory since ancient times. Medicinal plants, it is claimed, contain various active components, and they have a widely used synthetic medication option for treating cognitive and associated issues. Herbal medicines have aided in advancing medicine, and several innovative pharmaceuticals have already developed. For example, much research has backed the use of phytoconstituents in herbal medicines to treat Alzheimer’s disease (AD). Progressive memory loss, linguistic difficulties, melancholy, anxiety, mood swings, and psychosis are some of these symptoms. Objective: A systemic literature review of Bentham, Scopus, PubMed, Medline, and EMBASE (Elsevier) database was carried out to understand the study till March 2021. Conclusion: Although neurofibrillary tangle and cholinergic dysfunction, -amyloid plaquesdevelopment are critical features of AD, it is also linked to oxidative damage, disruption of other neurotransmitters, high levels of AGEs, neuroinflammation, hereditary and environmental variables. On the one hand, because of this complex etiology, responses to routinely used medications like memantine, donepezil, galantamine, and rivastigmine are unpredictable and frequently poor. On the other hand, their nonspecific anti-inflammatory and antioxidant effect and particular cholinesterase inhibitory activity support the use of herbal medications. Herbal drugs are also gaining popularity as a result of their supposed efficacy, safety, and accessibility.","PeriodicalId":382729,"journal":{"name":"Journal of Pharmaceutical Technology, Research and Management","volume":"4 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2021-11-08","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"117247584","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 1

Sanitizer: Corona and Boom in the Market 消毒剂:市场上的电晕和繁荣

Journal of Pharmaceutical Technology, Research and Management Pub Date : 2021-11-08 DOI: 10.15415/jptrm.2021.92008

Malkiet Kaur, Vivekanand Vishvakarma, M. Nagpal

{"title":"Sanitizer: Corona and Boom in the Market","authors":"Malkiet Kaur, Vivekanand Vishvakarma, M. Nagpal","doi":"10.15415/jptrm.2021.92008","DOIUrl":"https://doi.org/10.15415/jptrm.2021.92008","url":null,"abstract":"Background: Hand hygiene is a simple and efficient strategy for minimizing illness transmission in public and clinical settings. The development of SARS-CoV-2 has created enormous challenge to global public health. Currently, the efforts to prevent COVID-19 are supportive with a goal of minimizing transmission. Method: In this review, an extensive literature search was performed with help of various search engines such as Google, Google Scholar, sci-hub, Science direct, Pub med. The authors have summarized the active ingredients and mechanism of action of benzalkonium chloride and alcohol against bacteria and viruses. Various research reports and patents that have been formulated hand sanitizers to prevent virus has been compiled in this article. Results: From the literature, it was observed that alcohol-based hand sanitizers can efficiently disturb the activity of encapsulated bacteria’s or viruses. Researchers found that there are various forms of hand sanitizer’s i.e. liquid, gel, foam, spray and wipes and recommending best method of delivery out of these is difficult. Two basic requirements of hand sanitizers for maintaining hand hygiene is its compliance and its coverage to the whole hand. Conclusions: The viruses and bacteria’s causing disease should be successful in eliminating them with the help of current hand hygiene solutions. After reviewing the literature, it is concluded that there is a vast scope in development of hand hygiene products.","PeriodicalId":382729,"journal":{"name":"Journal of Pharmaceutical Technology, Research and Management","volume":"128 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2021-11-08","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"132424815","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Importance of Pharmacovigilance in Ayurveda 阿育吠陀药物警戒的重要性

Journal of Pharmaceutical Technology, Research and Management Pub Date : 2021-11-08 DOI: 10.15415/jptrm.2021.92009

Susheel Kumar, R. Arora, R. Babbar, Rajwinder Kaur

{"title":"Importance of Pharmacovigilance in Ayurveda","authors":"Susheel Kumar, R. Arora, R. Babbar, Rajwinder Kaur","doi":"10.15415/jptrm.2021.92009","DOIUrl":"https://doi.org/10.15415/jptrm.2021.92009","url":null,"abstract":"Introduction: Ayurveda has been introduced in India around 1500 BC. Ayurvedic medicines are more accepted these days as people are looking out for the natural medications. The major function of this system is to preserve the normal wellness of people and to cure the patient. These medicines, which are generally considered as safer, are now in the aura of doubt, due to some of the recent incidences of Adverse Drug Reaction (ADR), during their usage. Objective: Pharmacovigilance is an important step in Ayurveda to overcome and continuously monitor the ADR. Pharmacovigilance is the law and regulations for pharma industries, which deal with the detection, assessment, monitoring, understanding, prevention and reporting of adverse effects of medicines. Thus, this is the recurrent theme of ayurvedic pharmacology (dravyagunavigyan) and healing (chikitsa). The most important aim of pharmacovigilance, that is to enhance patient care and safety of the drug use, and as a result elevate rational drug use are recurring premise of ayurvedic pharmacology cology (dravyagunavigyan) and therapeutics (chikitsa). Methods: The data was collected from different websites and databases such as PubMed, Biomedical Sciences, Science Direct, Wiley Online Library, Google Scholar, WHO, Bentham science etc. A total of 80 articles were downloaded, studied, categorized and 52 were selected to write the manuscript. Results and Conclusion: There is requirement of an appropriate post-clinical surveillance program for ayurvedic drugs based on its quality, safety, and efficacy, for public health and disease management, which is now accessible in National Pharmacovigilance Programme for ASU (Ayurveda, Siddha, Unani) drugs, Ayurveda has explained a broad hypothesis on homeopathy medicines, in relation with its usage, causal ADR, treatment and its prevention. Spontaneous reporting of ADR related to Ayurveda plays an essential role in the identification and detection of new signals and communicating novel research questions.","PeriodicalId":382729,"journal":{"name":"Journal of Pharmaceutical Technology, Research and Management","volume":"41 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2021-11-08","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"121651035","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0