Phytoconstituents in Breast Cancer Prevention

Shreya Sood, Sushma Devi, Thakur Gurjeet Singh, A. Kaur, Vinita Singh, Prinsi Sahpuriya
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Abstract

Background: In today’s developing nations, breast cancer (BC) is among the foremost risk factor for women. The causes of mortality are still unclear, yet they are frequently related to socioeconomic level and way of life. Numerous clinical therapies have been employed up to this point, i.e., radiotherapy, hormonal treatment, targeted treatment, mastectomy, and treatment with drugs etc. Purpose: However, resistance development to chemotherapeutic drugs, radiation and hormonal therapy is one of the common problems for many of the patients with BC. Numerous studies have looked at the anti-cancer potential of natural products due to the fact that they are generally safe. Researchers’ interest is being drawn by phytochemicals from plants that are thought to be bioactive. In this review the formation and progression of breast cancer were also studied, along with the mode’s of activity and regulatory function of these phytoconstituents in major signalling networks within the cell. Conclusion: Phytoconstituents in Breast Cancer Prevention have potential future as well as the difficulties. So, need more study and instructions for experimental animals, medical research, and experimental in vitro and in vivo methods are critically evaluated.
预防乳腺癌的植物成分
背景:在当今的发展中国家,乳腺癌(BC)是女性最重要的危险因素之一。死亡原因尚不清楚,但往往与社会经济水平和生活方式有关。到目前为止,已经采用了许多临床治疗方法,如放疗、激素治疗、靶向治疗、乳房切除术、药物治疗等。目的:然而,对化疗药物、放疗和激素治疗的耐药是许多BC患者的共同问题之一。许多研究都着眼于天然产品的抗癌潜力,因为它们通常是安全的。研究人员的兴趣被从被认为具有生物活性的植物中提取的植物化学物质所吸引。本文还对乳腺癌的形成和发展进行了研究,并对这些植物成分在细胞内主要信号网络中的活性模式和调节功能进行了研究。结论:植物成分在乳腺癌防治中的应用前景广阔,但存在一定的困难。因此,需要对实验动物进行更多的研究和指导,进行医学研究,并对实验的体外和体内方法进行批判性的评估。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
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