Journal of the American Society of Cytopathology最新文献

{"title":"Interdisciplinary and inter-personnel issues during rapid on-site evaluation: an analysis of 2025 American Society of Cytopathology survey results.","authors":"Abha Goyal, Susan A Alperstein, Valentina Robila, Jeffrey K Mito, Vanda Torous, Jennifer Kernodle, Kristen E Natale, Jinous Saremian, Aziza Nassar","doi":"10.1016/j.jasc.2026.09.001","DOIUrl":"https://doi.org/10.1016/j.jasc.2026.09.001","url":null,"abstract":"<p><strong>Introduction: </strong>This study aimed to explore the interdisciplinary and interpersonnel issues that may arise in the setting of rapid on-site evaluation (ROSE) of fine-needle aspiration/core biopsy specimens.</p><p><strong>Materials and methods: </strong>A 17-question survey was distributed electronically to the members of the American Society of Cytopathology and the American Society for Cytology in 2025. The responses were obtained through SurveyMonkey and further analyzed.</p><p><strong>Results: </strong>A total of 280 unique responses were received per question. Majority participants were cytologists/cytology supervisors (60.3%) and pathologists/laboratory directors (35.2%). ROSE was performed by majority (96.1%) and was most often carried out by \"both cytologist and pathologist\" (45.5%) or by \"cytologist only\" (33.2%). Telecytology was utilized by 43.1% for ROSE. Frequently occurring preanalytic issues included mistiming of contacting cytology (71.4%) and inadequate clinical information (55.2%). Main analytic difficulties were space constraints (63.6%) and multiple passes already procured before cytology team's arrival (44.9%). Lack of respectful behavior towards cytology personnel was reported by 32.4%. The lack of understanding of the administrative personnel regarding the time spent on ROSE was reported by 40.2%. Issues largely associated with telecytology included: difficulty in visualizing crowded cell groups and on-site individual failing to show diagnostic cells to remote pathologist.</p><p><strong>Conclusions: </strong>This American Society of Cytopathology survey highlighted important interpersonnel/interdisciplinary issues that may arise in the current landscape of ROSE where cytologists have taken on an important role. Increased awareness of these issues may foster a more professional and collaborative work environment and drive improvements in current practice.</p>","PeriodicalId":38262,"journal":{"name":"Journal of the American Society of Cytopathology","volume":" ","pages":""},"PeriodicalIF":2.7,"publicationDate":"2026-09-23","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"149225202","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Treatment-related changes in cytopathology and small biopsies: an increasing array of morphological findings with expanding therapeutic options","authors":"Sara E. Monaco MD,&nbsp;Zahra Maleki MD,&nbsp;Erika F. Rodriguez MD, PhD","doi":"10.1016/j.jasc.2026.04.001","DOIUrl":"10.1016/j.jasc.2026.04.001","url":null,"abstract":"&lt;div&gt;&lt;ul&gt;&lt;li&gt;&lt;span&gt;•&lt;/span&gt;&lt;span&gt;&lt;div&gt;Small biopsies are ideal to obtain tissue in cancer patients undergoing treatment.&lt;/div&gt;&lt;/span&gt;&lt;/li&gt;&lt;li&gt;&lt;span&gt;•&lt;/span&gt;&lt;span&gt;&lt;div&gt;There are key patterns of changes to consider when evaluating these specimens.&lt;/div&gt;&lt;/span&gt;&lt;/li&gt;&lt;li&gt;&lt;span&gt;•&lt;/span&gt;&lt;span&gt;&lt;div&gt;The morphological changes seen can be important to explain treatment response.&lt;/div&gt;&lt;/span&gt;&lt;/li&gt;&lt;/ul&gt;&lt;/div&gt;&lt;div&gt;&lt;h3&gt;Introduction&lt;/h3&gt;&lt;div&gt;Minimally invasive biopsies are ideal for procuring tumor tissue for cancer patients at various stages. With an expanding array of therapeutic agents and variable response of tumors to these agents, these small samples can also be valuable during or after treatment to determine response, residual disease, or new diagnosis.&lt;/div&gt;&lt;/div&gt;&lt;div&gt;Minimally invasive biopsies are ideal for procuring tumor tissue for cancer patients at various stages. With an expanding array of therapeutic agents and variable response of tumors to these agents, these small samples can also be valuable during or after treatment to determine response, residual disease, or new diagnosis.&lt;/div&gt;&lt;div&gt;&lt;h3&gt;Materials and methods&lt;/h3&gt;&lt;div&gt;In this narrative review, cytology and core biopsy cases mentioning therapy or treatment related changes were reviewed to look at different patterns that can arise with illustrative examples to provide morphologic clues to help when evaluating these specimens.&lt;/div&gt;&lt;/div&gt;&lt;div&gt;In this narrative review, cytology and core biopsy cases mentioning therapy or treatment related changes were reviewed to look at different patterns that can arise with illustrative examples to provide morphologic clues to help when evaluating these specimens.&lt;/div&gt;&lt;div&gt;&lt;h3&gt;Results&lt;/h3&gt;&lt;div&gt;The main patterns of morphological changes include epithelial atypia, epithelial and cellular degeneration, stromal changes, amorphous/foreign material, histiocytic and granulomatous inflammation, high-grade transformations, and immunophenotypic changes. Careful review of these cases with illustrative examples can help to maximize concordance between preliminary diagnoses at rapid on-site evaluation and final interpretations, in addition to providing guidance to the proceduralist during the procedure and helping to explain indeterminate imaging findings for cancer patients undergoing therapy.&lt;/div&gt;&lt;/div&gt;&lt;div&gt;The main patterns of morphological changes include epithelial atypia, epithelial and cellular degeneration, stromal changes, amorphous/foreign material, histiocytic and granulomatous inflammation, high-grade transformations, and immunophenotypic changes. Careful review of these cases with illustrative examples can help to maximize concordance between preliminary diagnoses at rapid on-site evaluation and final interpretations, in addition to providing guidance to the proceduralist during the procedure and helping to explain indeterminate imaging findings for cancer patients undergoing therapy.&lt;/div&gt;&lt;div&gt;&lt;h3&gt;Conclusions&lt;/h3&gt;&lt;div&gt;Given the increased use of novel therap","PeriodicalId":38262,"journal":{"name":"Journal of the American Society of Cytopathology","volume":"15 5","pages":"Pages 315-330"},"PeriodicalIF":2.7,"publicationDate":"2026-09-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"147843940","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"When hrHPV Misses the Mark: The Critical Role of Cytology in Detecting Cervical High-Grade Squamous Intraepithelial Lesion (HGSIL) and Squamous Cell Carcinoma (SCC)","authors":"Afreen Karimkhan MD,&nbsp;Hadel Go MD,&nbsp;Wei Sun MD,&nbsp;Absia Jabbar MD,&nbsp;Osvaldo Hernandez MD,&nbsp;Yan Shi MD, PhD,&nbsp;Negin Shafizadeh MD,&nbsp;Esther Adler MD,&nbsp;Aylin Simsir MD,&nbsp;Rong Xia MD, PhD","doi":"10.1016/j.jasc.2026.08.074","DOIUrl":"10.1016/j.jasc.2026.08.074","url":null,"abstract":"","PeriodicalId":38262,"journal":{"name":"Journal of the American Society of Cytopathology","volume":"15 5","pages":"Pages S41-S42"},"PeriodicalIF":2.7,"publicationDate":"2026-09-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"149010740","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"The Utility of Pap Testing in Women Outside Standard Screening Age Guidelines","authors":"Israh Akhtar MD, FIAC,&nbsp;Kassaye Firde MD,&nbsp;Olabisi Afolayan-Oloye MD, MPH","doi":"10.1016/j.jasc.2026.08.080","DOIUrl":"10.1016/j.jasc.2026.08.080","url":null,"abstract":"","PeriodicalId":38262,"journal":{"name":"Journal of the American Society of Cytopathology","volume":"15 5","pages":"Page S44"},"PeriodicalIF":2.7,"publicationDate":"2026-09-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"149010745","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Where Are We Going Wrong? Challenges in Recruiting Cytopathology Fellows: A Multi Factor Institutional Review","authors":"Israh Akhtar MD, FIAC","doi":"10.1016/j.jasc.2026.08.040","DOIUrl":"10.1016/j.jasc.2026.08.040","url":null,"abstract":"","PeriodicalId":38262,"journal":{"name":"Journal of the American Society of Cytopathology","volume":"15 5","pages":"Page S21"},"PeriodicalIF":2.7,"publicationDate":"2026-09-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"149010796","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Cervical Cytology Screening in the Arab World: A Scoping Review of Program Status, Bethesda System Findings, and Barriers Across All 22 Arab League Member States","authors":"Aisha Al Abri MSc","doi":"10.1016/j.jasc.2026.08.084","DOIUrl":"10.1016/j.jasc.2026.08.084","url":null,"abstract":"","PeriodicalId":38262,"journal":{"name":"Journal of the American Society of Cytopathology","volume":"15 5","pages":"Page S46"},"PeriodicalIF":2.7,"publicationDate":"2026-09-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"149010802","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Atypical Glandular Cells Correlated with Clinical Variables and Outcomes: A 5-Year Retrospective Analysis from a Safety-Net Hospital","authors":"Amr Soliman MD,&nbsp;Genesys Santana MPhil, MSc,&nbsp;Chandini Madeswaran MD,&nbsp;Devereaux Sellers MD, MBA,&nbsp;Santhi Ganesan MD","doi":"10.1016/j.jasc.2026.08.087","DOIUrl":"10.1016/j.jasc.2026.08.087","url":null,"abstract":"","PeriodicalId":38262,"journal":{"name":"Journal of the American Society of Cytopathology","volume":"15 5","pages":"Page S47"},"PeriodicalIF":2.7,"publicationDate":"2026-09-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"149010917","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"HPV PCR Testing on Head & Neck Fine Needle Aspiration Samples Using PreservCyt, An Institutional Experience","authors":"Nicholas Stanzione MD,&nbsp;Karime Gonzalez Lupercio,&nbsp;Po Chu Fung MBA, SCT(ASCP),&nbsp;Shangxin Yang PhD, D(ABMM)","doi":"10.1016/j.jasc.2026.08.089","DOIUrl":"10.1016/j.jasc.2026.08.089","url":null,"abstract":"","PeriodicalId":38262,"journal":{"name":"Journal of the American Society of Cytopathology","volume":"15 5","pages":"Page S48"},"PeriodicalIF":2.7,"publicationDate":"2026-09-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"149011009","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Optimizing Slide Utilization during ROSE: Evaluating Pass Efficiency in EBUS-Guided Lymph Node Staging for Primary Lung Cancer","authors":"Arkar Htoo MD,&nbsp;Erika Doxtader MD,&nbsp;Juan Xing MD,&nbsp;Sangi Goel MD,&nbsp;James Bena BS,&nbsp;Dawn Underwood MEd, CT(ASCP),&nbsp;Akeesha Shah MD","doi":"10.1016/j.jasc.2026.08.049","DOIUrl":"10.1016/j.jasc.2026.08.049","url":null,"abstract":"","PeriodicalId":38262,"journal":{"name":"Journal of the American Society of Cytopathology","volume":"15 5","pages":"Pages S27-S28"},"PeriodicalIF":2.7,"publicationDate":"2026-09-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"149011017","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Detection of Endometrial Cells (EMs) in Prospective Rescreening Post Genius™ Digital Diagnostics System (GDDS) Implementation","authors":"Joelle Tarquinio CT(ASCP),&nbsp;Kayleigh Bucci CT(ASCP)CM,&nbsp;Dawn Underwood MEd, CT(ASCP),&nbsp;Jennifer Brainard MD","doi":"10.1016/j.jasc.2026.08.035","DOIUrl":"10.1016/j.jasc.2026.08.035","url":null,"abstract":"","PeriodicalId":38262,"journal":{"name":"Journal of the American Society of Cytopathology","volume":"15 5","pages":"Page S18"},"PeriodicalIF":2.7,"publicationDate":"2026-09-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"149010696","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}