Journal of the American Society of Cytopathology最新文献_第2页

Cytomorphology and Clinicopathologic Correlation of Lung Adenocarcinoma with Hepatoid Features 肺腺癌与肝样特征的细胞形态学及临床病理相关性

Journal of the American Society of Cytopathology Pub Date : 2025-09-01 DOI: 10.1016/j.jasc.2025.07.050

Xiaoqi Lin MD, PhD

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PD-L1 Expression Associated with EGFR Wild-Type Non-Small Cell Lung Carcinoma in Asian Patients 亚洲患者中PD-L1表达与EGFR野生型非小细胞肺癌相关

Journal of the American Society of Cytopathology Pub Date : 2025-09-01 DOI: 10.1016/j.jasc.2025.07.043

Nikka Khorsandi MD, MPH , Amanda Borgen MD , Poonam Vohra MD , Peyman Samghabadi MD , Carlo De la Sancha MD , Autumn Mullins BS , Steven Long MD

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Cytologic-Histologic Correlation of Thyroid FNA Specimens: A Retrospective Study from a Single Institution 甲状腺FNA标本的细胞学-组织学相关性：来自单一机构的回顾性研究

Journal of the American Society of Cytopathology Pub Date : 2025-09-01 DOI: 10.1016/j.jasc.2025.07.038

Konara Mudiyanselage Maduhasi Bandara MD, Valerica Mateescu MD

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Next Generation Sequencing on Fine Needle Aspirate Smears of Non-Small Cell Lung Cancers: An Institutional Validation Study 非小细胞肺癌细针抽吸涂片的新一代测序：一项机构验证研究

Journal of the American Society of Cytopathology Pub Date : 2025-09-01 DOI: 10.1016/j.jasc.2025.07.115

Rebecca Crowther MD, PhD , None Alnoor MD , Hannah Krigman MD , Suzanne Crumley MD , Lulu Sun MD, PhD

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Cytology-Histology Correlation of Peritoneal Washings: A Review of 363 Cases 363例腹膜冲洗的细胞学-组织学相关性分析

Journal of the American Society of Cytopathology Pub Date : 2025-09-01 DOI: 10.1016/j.jasc.2025.07.082

Diane Carr DO, Sana Tabbara MD, Atousa Ordobazari MD, Ardeshir Hakam MD, Nini Khin MD

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Cytologic Features of Extramammary Paget's Disease on Cervico-Vaginal Cytology 乳腺外佩吉特病的宫颈阴道细胞学特征

Journal of the American Society of Cytopathology Pub Date : 2025-09-01 DOI: 10.1016/j.jasc.2025.07.064

Justin Burk DO, Suzanne Crumley MD, Ryan Mckinney CT(ASCP), Hannah Krigman MD

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Assessment of New and Evolving Technology for Rapid On-Site Evaluation (ROSE) by Telecytology 基于电信技术的快速现场评估（ROSE）新技术评估

Journal of the American Society of Cytopathology Pub Date : 2025-09-01 DOI: 10.1016/j.jasc.2025.07.124

Patrick Morse MD, Cody Weimholt DO, Cory Bernadt MD, PhD, Hannah Krigman MD, Suzanne Crumley MD

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Utilization of a TRBC1 and CD3 Double Stain for the Diagnosis of T-Cell Lymphoma in Cytology Specimens TRBC1和CD3双染色在细胞学标本中诊断t细胞淋巴瘤中的应用

Journal of the American Society of Cytopathology Pub Date : 2025-09-01 DOI: 10.1016/j.jasc.2025.07.052

Sarah Wu MD, PhD, Geraldine Pinkus MD, Jeffrey Mito MD, PhD

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Assessment of reprocessed ThinPrep cytology cases after glacial acetic acid wash procedure using the Hologic Genius Digital Diagnostics System 使用Hologic Genius数字诊断系统评估冰醋酸洗涤后再处理的ThinPrep细胞学病例。

Journal of the American Society of Cytopathology Pub Date : 2025-09-01 DOI: 10.1016/j.jasc.2025.05.008

Lakshmi Harinath MD, MPH , Jonee Matsko SCT, MB , Amy Colaizzi SCT , Xianxu Zeng PhD, MD , Esther Elishaev MD , Rohit Bhargava MD , Liron Pantanowitz MD, PhD, MHA , Chengquan Zhao MD

{"title":"Assessment of reprocessed ThinPrep cytology cases after glacial acetic acid wash procedure using the Hologic Genius Digital Diagnostics System","authors":"Lakshmi Harinath MD, MPH , Jonee Matsko SCT, MB , Amy Colaizzi SCT , Xianxu Zeng PhD, MD , Esther Elishaev MD , Rohit Bhargava MD , Liron Pantanowitz MD, PhD, MHA , Chengquan Zhao MD","doi":"10.1016/j.jasc.2025.05.008","DOIUrl":"10.1016/j.jasc.2025.05.008","url":null,"abstract":"<div><h3>Introduction</h3><div>This study focuses on ThinPrep Pap tests with a low to borderline number of cells and the performance of AI-assisted digital systems in cases that have undergone the acetic acid wash procedure (AAW).</div></div><div><h3>Materials and methods</h3><div>Four hundred sixty-two cases initially interpreted as unsatisfactory and finally interpreted as satisfactory after AAW procedure were included in the study. These ThinPrep Pap slides were scanned using the Genius Digital Diagnostic System (GDDS).</div></div><div><h3>Results</h3><div><span>Overall agreement between GDDS and Original ThinPrep Interpretation (OTPI) was 63.2% for diagnostic match (Negative for Intraepithelial Lesion, ASCUS, Low Grade Squamous Intraepithelial Lesion, Atypical Squamous Cells, High Grade, Atypical Glandular Cells, or unsatisfactory), and 66.0% when ASCUS + diagnoses are grouped. Out of the 462 cases, 364 (78.8%) were called Negative for Intraepithelial Lesion based upon the manual OTPI, as opposed to 310 (67.1%) reviewed using the GDDS. There were 17.5%, 1.3%, 0.9% and 1.5% cases called Atypical Squamous Cells of Undetermined Significance, Low Grade Squamous Intraepithelial Lesion, Atypical Squamous Cells, High Grade Cannot be Excluded, and Atypical Glandular Cells respectively on OTPI, as opposed to 24.7%, 3.0%, 0.6% and 1.5% respectively by the GDDS. Only 3.0% of the cases were deemed unsatisfactory by GDDS. All the cases with high grade results in the subsequent cervical biopsy were diagnosed as at least Atypical Squamous Cells of Undetermined Significance and above by the GDDS. The diagnostic agreement between GDDS and biopsy was 65.2% compared to 58.7% for OTPI, although this is not statistically significantly different, (χ</span><sup>2</sup> (1) = 0.415, <em>P</em> = 0.519).</div></div><div><h3>Conclusions</h3><div>Our results demonstrate that the GDDS can be successfully used to screen ThinPrep Pap Tests that have undergone the AAW procedure.</div></div>","PeriodicalId":38262,"journal":{"name":"Journal of the American Society of Cytopathology","volume":"14 5","pages":"Pages 347-357"},"PeriodicalIF":0.0,"publicationDate":"2025-09-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144561441","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Outcome of atypical urothelial cells (AUC) in patients without prior history of urothelial carcinoma 非典型性尿路上皮细胞（AUC）在无既往尿路上皮癌患者中的预后。

Journal of the American Society of Cytopathology Pub Date : 2025-09-01 DOI: 10.1016/j.jasc.2025.06.001

Emily Van Tassel BS, CT(ASCP) , Josh Howell MAOL, SCT(ASCP) , Kaitlin Walls BS, CT(ASCP) , William Crabtree PhD, SCT(ASCP)

{"title":"Outcome of atypical urothelial cells (AUC) in patients without prior history of urothelial carcinoma","authors":"Emily Van Tassel BS, CT(ASCP) , Josh Howell MAOL, SCT(ASCP) , Kaitlin Walls BS, CT(ASCP) , William Crabtree PhD, SCT(ASCP)","doi":"10.1016/j.jasc.2025.06.001","DOIUrl":"10.1016/j.jasc.2025.06.001","url":null,"abstract":"<div><h3>Introduction</h3><div>An “atypical” diagnosis is subjective in any cytologic specimen, and the interpretation is often problematic. To mitigate this issue, The Paris System for Reporting Urinary Cytology was released in 2016. Its goal was to standardize the criteria for urine cytology specimens. Atypical urothelial cells (AUC) can be a difficult diagnosis for clinicians to utilize, as it does not give a definitive answer as to whether a patient has a urothelial malignancy or not. However, a diagnosis of AUC is an acceptable option for a urine specimen that has characteristics that are clearly abnormal but fall short of malignancy.</div></div><div><h3>Materials and methods</h3><div>Voided urine specimens signed out as AUC in 2019 and 2020 from patients without a history of urothelial carcinoma were identified using the laboratory information system. Patient history, clinical history, and follow-up through April of 2024 were recorded. Selected cases were reviewed microscopically for the AUC diagnosis on the voided urine specimen.</div></div><div><h3>Results</h3><div>Of 151 cases identified, 50 (33.0%) cases included biopsy follow-up, and one case had follow-up of a ureteral brushing. Of those 51 cases, 33 (64.7%) cases had a positive follow-up, 12 (23.5%) cases had a negative follow-up, and 6 (11.8%) cases had a follow-up that showed a nonurothelial malignancy.</div></div><div><h3>Conclusions</h3><div>Previous similar studies have evaluated the outcome of AUC diagnoses, but it is common for those patients to have had a prior history of urothelial carcinoma. In this study, the diagnosis of AUC correlates to an eventual diagnosis of malignancy in 63.0% of cases without a known history of urothelial carcinoma. Based upon these results and previous studies, AUC appears to be a beneficial diagnosis for the patient but may lead to variable outcomes in patient follow-up.</div></div>","PeriodicalId":38262,"journal":{"name":"Journal of the American Society of Cytopathology","volume":"14 5","pages":"Pages 334-340"},"PeriodicalIF":0.0,"publicationDate":"2025-09-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144812546","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0