A. Forestier , M. Guehl , E. Lyon , E. Reyes-Gomez , S. Besnard , C. Benzimra , C. Escriou , S. Blot
{"title":"Un cas d’encéphalite limbique féline","authors":"A. Forestier , M. Guehl , E. Lyon , E. Reyes-Gomez , S. Besnard , C. Benzimra , C. Escriou , S. Blot","doi":"10.1016/j.anicom.2025.03.002","DOIUrl":"10.1016/j.anicom.2025.03.002","url":null,"abstract":"<div><div>Un chat mâle castré de 4,5 ans a été présenté pour des manifestations récurrentes évoquant des crises épileptiques focales associées à une modification du comportement. L’examen IRM de l’encéphale, l’analyse du liquide cérébrospinal, et l’examen électroencéphalographique étaient évocateurs d’une encéphalite limbique, sans pour autant permettre de l’affirmer avec certitude. L’encéphalite limbique a pu être confirmer avec certitude grâce à l’examen anatomopathologique post-mortem couplé au dosage sérique spécifique des anticorps anti-LGI1. L’encéphalite limbique féline à anticorps anti-LGI1 (EL-LGI1) est une forme d’encéphalite auto-immune, récemment reconnue chez les chats, possiblement causée par des anticorps ciblant la protéine LGI1. Similaire à sa forme humaine, l’EL-LGI1 chez les chats se manifeste par des crises épileptiques focales, souvent accompagnées d’automatismes orofaciaux et de changement de comportement comme l’agressivité. Le diagnostic repose sur la détection des anticorps anti-LGI1, bien que ce dosage ne soit pas disponible en routine en médecine vétérinaire et particulièrement en France. Ce cas illustre un cas typique d’encéphalite limbique pour lequel un diagnostic a été établi avec certitude en post-mortem et souligne la difficulté du diagnostic pré-mortem.</div></div><div><div>A 4.5-year-old neutered male cat was presented with recurrent manifestations suggesting focal seizures associated with behavioral changes. MRI of the brain, analysis of cerebrospinal fluid, and electroencephalographic examination were suggestive of limbic encephalitis, although they could not confirm it with certainty. Limbic encephalitis was definitively confirmed through post-mortem histopathological examination combined with specific serum testing for anti-LGI1 antibodies. Feline limbic encephalitis with anti-LGI1 (EL-LGI1) is a form of autoimmune encephalitis recently recognized in cats, possibly caused by antibodies targeting the LGI1 protein. Similar to its human form, EL-LGI1 in cats manifests as focal seizures, often accompanied by oro-facial automatisms and behavioral changes such as aggression. The diagnosis relies on the detection of anti-LGI1 antibodies, although this test is not routinely available in veterinary medicine, especially in France. This case illustrates a typical example of limbic encephalitis for which a definitive diagnosis was established post-mortem and highlights the challenges of pre-mortem diagnosis.</div></div>","PeriodicalId":38077,"journal":{"name":"Revue Veterinaire Clinique","volume":"60 3","pages":"Pages 121-129"},"PeriodicalIF":0.0,"publicationDate":"2025-08-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144679983","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Stabilisation d’une instabilité atlanto-axiale associée à une dysplasie atlanto-occipitale par plaque dorsale imprimée en 3D : 3 chiens","authors":"M. Guichard, F. Sager","doi":"10.1016/j.anicom.2025.06.005","DOIUrl":"10.1016/j.anicom.2025.06.005","url":null,"abstract":"","PeriodicalId":38077,"journal":{"name":"Revue Veterinaire Clinique","volume":"60 3","pages":"Pages 172-174"},"PeriodicalIF":0.0,"publicationDate":"2025-08-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144680037","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Rôle du microbiote intestinal dans la pathogénie de la maladie lithiasique chez le chat","authors":"P. Joubran, F. Roux, J.-Y. Deschamps","doi":"10.1016/j.anicom.2025.06.008","DOIUrl":"10.1016/j.anicom.2025.06.008","url":null,"abstract":"","PeriodicalId":38077,"journal":{"name":"Revue Veterinaire Clinique","volume":"60 3","pages":"Pages 180-181"},"PeriodicalIF":0.0,"publicationDate":"2025-08-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144679485","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Atrophies progressives de la rétine du chien, rétinopathies pigmentaires de l’homme : similitudes et différences","authors":"G. Chaudieu","doi":"10.1016/j.anicom.2025.02.002","DOIUrl":"10.1016/j.anicom.2025.02.002","url":null,"abstract":"<div><div>Les rétinopathies pigmentaires de l’homme et les atrophies progressives de la rétine du chien, dont les classifications sont initialement rappelées, sont homologues à beaucoup d’égards. Leur phénotype est dominé par une perte progressive de vision avec une cécité terminale très fréquente. Elles présentent une triple hétérogénéité : clinique, génétique et moléculaire. Les données cliniques sont rappelées, comparativement dans les deux espèces, pour les formes isolées et les formes syndromiques. Leur transmission mendélienne est majoritairement autosomique récessive, surtout chez le chien où ce mode est quasi-exclusif. Des gènes communs sont impliqués, leurs mutations sont plus nombreuses chez l’homme, chez qui le pourcentage de cas sporadiques est élevé, alors que le suivi d’une lignée affectée offre une facilité d’étude propre à la structuration génétique de l’espèce canine en races sélectionnées. Ces facteurs contribuent à faire du chien un modèle privilégié transposable à l’homme dans la recherche en thérapie génique rétinienne.</div></div><div><div>Human pigmentary retinopathies and canine progressive retinal atrophies, whose classifications are initially recalled, are homologous in many aspects. Their phenotype is dominated by a progressive vision loss with very frequent terminal blindness. They present a triple heterogeneity: clinical, genetic and molecular. Clinical data are reviewed comparatively in these two species for isolated and syndromic forms. Their mendelian transmission is mostly autosomal recessive, especially in dogs, where this mode is almost exclusive. Common genes are involved, their mutations are most numerous in humans, in whom the percentage of sporadic cases is high, while an affected breeding line following offers an ease of study specific to the genetic structuring of the canine species into selected breeds. These factors contribute to making the dog a privileged model that can be transposed to humans in retina gene therapy research.</div></div>","PeriodicalId":38077,"journal":{"name":"Revue Veterinaire Clinique","volume":"60 2","pages":"Pages 64-82"},"PeriodicalIF":0.0,"publicationDate":"2025-06-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143882050","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"L’impact de la rétraction du nerf vague sur la paralysie laryngée unilatérale gauche postopératoire après fermeture chirurgicale du canal artériel persistant chez le chien","authors":"S. Manzoni, M. Santos, N. Van Israël, A. Bongartz","doi":"10.1016/j.anicom.2025.01.008","DOIUrl":"10.1016/j.anicom.2025.01.008","url":null,"abstract":"","PeriodicalId":38077,"journal":{"name":"Revue Veterinaire Clinique","volume":"60 2","pages":"Pages 118-120"},"PeriodicalIF":0.0,"publicationDate":"2025-06-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143881338","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"À propos de 10 cas de shunts intrahépatiques traités par chirurgie endovasculaire","authors":"H. Brissot, P. Degail, T. Larcher","doi":"10.1016/j.anicom.2025.01.005","DOIUrl":"10.1016/j.anicom.2025.01.005","url":null,"abstract":"","PeriodicalId":38077,"journal":{"name":"Revue Veterinaire Clinique","volume":"60 2","pages":"Pages 110-111"},"PeriodicalIF":0.0,"publicationDate":"2025-06-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143881340","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"L’utilité des parasites ou l’utilité de l’inutile","authors":"M. Gharbi","doi":"10.1016/j.anicom.2024.12.006","DOIUrl":"10.1016/j.anicom.2024.12.006","url":null,"abstract":"<div><div>Les parasites sont des êtres vivants qui vivent aux dépens d’autres sans les tuer. Certains sont à l’origine de problèmes de santé chez l’homme et les animaux poussant les praticiens de santé à recourir aux antiparasitaires médicamenteux. Néanmoins, environ 40 % des espèces animales vivantes sont des parasites. On oublie souvent qu’ils rendent plusieurs services écosystémiques et que plusieurs d’entre eux sont peu ou pas pathogènes. Le vétérinaire doit développer une connaissance fine des parasites, de l’épidémiologie parasitaire et des méthodes modernes de lutte contre ces parasites, qui devrait reposer sur la mise en place d’un « panier d’options de lutte » et ne pas se limiter aux antiparasitaires médicamenteux classiques. Un débat doit être initié pour faire réussir cette mutation des pratiques vétérinaires.</div></div><div><div>Parasites live on other animals without killing them. Some of these parasites generate health problems for humans and animals pushing health practitioners to use antiparasitic chemical drugs. Nevertheless, approximately 40% of the living animal species are parasites and we forget that these parasites have several ecosystem services and many of them are lightly or not pathogenic. Veterinary doctor should develop his knowledge on parasites, on the epidemiology of parasitic diseases and the modern methods of fighting these parasites that could be performed using a “basket of control options” and not limited to chemical antiparasitic drugs. A debate should be initiated to succeed the mutations of veterinary practice.</div></div>","PeriodicalId":38077,"journal":{"name":"Revue Veterinaire Clinique","volume":"60 2","pages":"Pages 83-88"},"PeriodicalIF":0.0,"publicationDate":"2025-06-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143882048","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Étude clinique portant sur 30 cas de torsion de lobe hépatique chez le lapin (Oryctolagus cuniculus) entre janvier 2021 et février 2024","authors":"C. Louvard , L. Mathieu","doi":"10.1016/j.anicom.2025.01.007","DOIUrl":"10.1016/j.anicom.2025.01.007","url":null,"abstract":"","PeriodicalId":38077,"journal":{"name":"Revue Veterinaire Clinique","volume":"60 2","pages":"Pages 115-117"},"PeriodicalIF":0.0,"publicationDate":"2025-06-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143881337","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
J.-L. Hardy, G. Guyon, M. Cambournac, C. Damoiseaux, C. Bismuth
{"title":"Apport de l’échographie transœsophagienne dans le traitement des shunts intrahépatiques portosystémiques par voie endovasculaire chez le chien : étude préliminaire","authors":"J.-L. Hardy, G. Guyon, M. Cambournac, C. Damoiseaux, C. Bismuth","doi":"10.1016/j.anicom.2025.01.006","DOIUrl":"10.1016/j.anicom.2025.01.006","url":null,"abstract":"","PeriodicalId":38077,"journal":{"name":"Revue Veterinaire Clinique","volume":"60 2","pages":"Pages 112-114"},"PeriodicalIF":0.0,"publicationDate":"2025-06-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143881336","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}