Revue Veterinaire Clinique最新文献

{"title":"TP53 as a prognostic biomarker in canine lymphoma: Insights from a targeted next-generation sequencing approach","authors":"L. Aresu","doi":"10.1016/j.anicom.2026.06.005","DOIUrl":"10.1016/j.anicom.2026.06.005","url":null,"abstract":"","PeriodicalId":38077,"journal":{"name":"Revue Veterinaire Clinique","volume":"61 3","pages":"Pages 168-169"},"PeriodicalIF":0.0,"publicationDate":"2026-08-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"148647296","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Que penser des mutations « yeux bleus » chez le chat ?","authors":"G. Chaudieu,&nbsp;L. Siméon,&nbsp;C. Cassagnes","doi":"10.1016/j.anicom.2025.12.004","DOIUrl":"10.1016/j.anicom.2025.12.004","url":null,"abstract":"<div><div>Les yeux bleus, précisément les iris bleus, sont un caractère esthétique apprécié dans certaines races félines. Certaines particularités oculaires physiologiques associées sont révélées par l’examen clinique. Chez les chats dont le blanc est dominant dans la robe blanche ou sa panachure, la couleur bleue de l’iris est incomplètement dominante et des cas de surdité congénitale neurosensorielle sont répertoriés, en lien avec une dégénérescence cochléaire postnatale corrélée à la présence d’au moins un allèle <em>W.</em> Le patron <em>colourpoint</em> typique du Siamois est associé à des yeux obligatoirement bleus et dépend d’un allèle situé au locus C, où se trouve le gène TYR. L’une des formes alléliques peut provoquer l’albinisme. Chez certains sujets <em>c</em>^<em>s</em><em>/c</em>^<em>s</em>, l’ésotropie peut apparaître dès l’âge de 3<!--> <!-->mois en raison d’un manque de régulation de la croissance axonale des fibres ganglionnaires. L’œil bleu dominant a une pénétrance incomplète et s’accompagne d’une panachure limitée à expressivité variable dans plusieurs races. Ce phénotype peut inclure une perte auditive neurosensorielle. Trois mutations du gène <em>PAX3</em> ont été identifiées, et une quatrième est en cours d’identification. Des conseils d’élevage sont fournis dans chaque situation, le diagnostic de surdité faisant nécessairement appel à la recherche des potentiels évoqués auditifs.</div></div><div><div>Blue eye, precisely blue iris, is an appreciated aesthetic trait in some feline breeds. Some associated physiological ocular peculiarities are revealed by the clinical examination. In cats with a dominant white coat or a large white spotting, the blue color of the iris is incompletely dominant and cases of sensorineural congenital deafness have been recorded, in connection with postnatal cochlear degeneration correlated with the presence of at least one <em>W</em> allele. The typical Siamese colourpoint pattern is associated with obligatory blue eyes and depends on an allele located at the C locus, where the TYR gene is located. One of the allelic forms can cause albinism. In some <em>c</em>^<em>s</em><em>/c</em>^<em>s</em> subjects, esotropia may appear as early as 3 months of age due to a lack of regulation of axonal growth of ganglion fibers. The dominant blue eye has incomplete penetrance and is accompanied by limited white spotting with variable expressivity in several breeds. This phenotype may include sensorineural hearing loss. Three mutations in the <em>PAX3</em> gene have been identified, and a fourth is in the process of being identified. Breeding advice is provided in each situation, the diagnosis of deafness necessarily calling for the search for Brainstain Auditory Evoked Response testing.</div></div>","PeriodicalId":38077,"journal":{"name":"Revue Veterinaire Clinique","volume":"61 3","pages":"Pages 130-143"},"PeriodicalIF":0.0,"publicationDate":"2026-08-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"148647298","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Syndrome hémophagocytaire : étude rétrospective à propos de 13 cas","authors":"T. Chenal,&nbsp;A. Prieux,&nbsp;F. Granat,&nbsp;C. Trumel","doi":"10.1016/j.anicom.2026.06.004","DOIUrl":"10.1016/j.anicom.2026.06.004","url":null,"abstract":"","PeriodicalId":38077,"journal":{"name":"Revue Veterinaire Clinique","volume":"61 3","pages":"Pages 166-167"},"PeriodicalIF":0.0,"publicationDate":"2026-08-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"148647294","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Évaluation des performances diagnostiques de la bandelette urinaire pour la détection d’une protéinurie douteuse ou pathologique chez le chat","authors":"É. Postic,&nbsp;A. Bertin,&nbsp;B. Reynolds,&nbsp;C. Trumel,&nbsp;R. Lavoué","doi":"10.1016/j.anicom.2026.06.003","DOIUrl":"10.1016/j.anicom.2026.06.003","url":null,"abstract":"","PeriodicalId":38077,"journal":{"name":"Revue Veterinaire Clinique","volume":"61 3","pages":"Pages 161-162"},"PeriodicalIF":0.0,"publicationDate":"2026-08-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"148647395","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Médecine vétérinaire intégrative","authors":"G. Chaudieu","doi":"10.1016/j.anicom.2026.06.001","DOIUrl":"10.1016/j.anicom.2026.06.001","url":null,"abstract":"","PeriodicalId":38077,"journal":{"name":"Revue Veterinaire Clinique","volume":"61 3","pages":"Pages 157-158"},"PeriodicalIF":0.0,"publicationDate":"2026-08-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"148646816","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Intervalles de référence des ratios métanéphrines/créatinine urinaire chez le chien : comparaison des ratios sur échantillons acidifiés et non acidifiés collectés par cystocentèse","authors":"S. Niederlender,&nbsp;K. Museux,&nbsp;S. Valentin","doi":"10.1016/j.anicom.2026.06.007","DOIUrl":"10.1016/j.anicom.2026.06.007","url":null,"abstract":"","PeriodicalId":38077,"journal":{"name":"Revue Veterinaire Clinique","volume":"61 3","pages":"Pages 159-160"},"PeriodicalIF":0.0,"publicationDate":"2026-08-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"148647301","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Étude comparative de 2 techniques d’étalements de prélèvement de moelle osseuse : étalement direct et étalement après enrichissement","authors":"L. Thouvenin,&nbsp;P. Bernard,&nbsp;A. Bertin,&nbsp;F. Granat,&nbsp;C. Trumel","doi":"10.1016/j.anicom.2026.06.008","DOIUrl":"10.1016/j.anicom.2026.06.008","url":null,"abstract":"","PeriodicalId":38077,"journal":{"name":"Revue Veterinaire Clinique","volume":"61 3","pages":"Pages 170-172"},"PeriodicalIF":0.0,"publicationDate":"2026-08-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"148647297","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Les parasites des carnivores domestiques, stop aux idées reçues !","authors":"M. Gharbi","doi":"10.1016/j.anicom.2025.12.003","DOIUrl":"10.1016/j.anicom.2025.12.003","url":null,"abstract":"<div><div>Les parasites sont des êtres vivants qui vivent aux dépens d’autres êtres vivants sans objectif de les tuer. Environ, 40 % des espèces animales décrites répondent à cette définition. Plusieurs d’entre elles affectent les animaux domestiques. Depuis quelques années, deux grandes nouvelles demandes sociétales se sont exprimées : que les animaux de compagnie soient exempts de toute parasitose avec l’objectif prioritaire de préserver les trois santés. Pour réussir ce défi, le vétérinaire doit avoir une connaissance fine des parasites et des parasitoses, notamment leur épidémiologie locale. Il doit également respecter certaines recommandations comme : ne pas avoir automatiquement l’objectif d’éliminer totalement les parasites chez les animaux, prendre en considération les trois santés (approche « Une seule santé ») et non deux (approche « Une seule médecine » qui considère la relation entre la médecine humaine et la médecine vétérinaire sans prise en compte de la santé des écosystèmes), cibler les parasites à plusieurs niveaux en adoptant une approche de lutte intégrée, considérer les expressions cliniques inhabituelles des parasitoses… En d’autres termes, penser autrement l’approche d’étude et de lutte contre les parasites.</div></div><div><div>Parasites are living beings that live at the expense of other living beings without aiming killing them. Approximately, 40% of described animal species are under this definition. Many of them affect domestic animals. Since the past few years, two new societal requests were expressed: companion animals should be exempt of parasites with a priority objective to preserve the three health. In order to succeed in this challenge, the veterinarian could have a fine knowledge of parasites and parasitic diseases, mainly the local epidemiology. He could also respect some recommendations like: not having systematically to aim total elimination of the parasites in animals, consider the three health (“One Health” approach) and not two (“One Medicine” approach that consider the relation between human health and animal health without considering the ecosystem health), target parasites at several levels by adopting an integrated control approach, consider the unusual clinical expression of parasitic diseases… In other words, think differently the study and control approach of parasites.</div></div>","PeriodicalId":38077,"journal":{"name":"Revue Veterinaire Clinique","volume":"61 3","pages":"Pages 144-150"},"PeriodicalIF":0.0,"publicationDate":"2026-08-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"148646817","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Intérêt de l’électrophorèse des protéines urinaires en gel d’agarose (SDS-AGE) chez les chiens atteints de maladie rénale chronique protéinurique : un potentiel outil prédictif de la progression et de la survie","authors":"C. Benoit,&nbsp;Anne Geffre,&nbsp;C. TrumeL,&nbsp;B. Reynolds,&nbsp;R. Lavoue","doi":"10.1016/j.anicom.2026.06.006","DOIUrl":"10.1016/j.anicom.2026.06.006","url":null,"abstract":"","PeriodicalId":38077,"journal":{"name":"Revue Veterinaire Clinique","volume":"61 3","pages":"Pages 163-165"},"PeriodicalIF":0.0,"publicationDate":"2026-08-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"148647295","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Comparative evaluation of generalist and veterinary specialized large language models for clinical reasoning support in veterinary medicine: A blinded multi-expert assessment","authors":"T. Audouin,&nbsp;E. Asimus,&nbsp;C. Béata,&nbsp;G. Blanchard,&nbsp;B. Michaud,&nbsp;J. Monot,&nbsp;H. Pouliquen,&nbsp;D. Sayag,&nbsp;J.L. Cadoré,&nbsp;J. Hernandez","doi":"10.1016/j.anicom.2026.05.001","DOIUrl":"10.1016/j.anicom.2026.05.001","url":null,"abstract":"<div><h3>Background</h3><div>Large language models (LLMs) are now being used in veterinary practice, but their clinical reasoning capabilities remain poorly assessed in this context.</div></div><div><h3>Material and methods</h3><div>Ten LLMs (six general-purpose models and four specialised in veterinary medicine) were compared across ten real-world clinical cases spanning eight specialities. Certified veterinary specialists, working in a blinded manner, assessed the responses using a six-dimensional scoring grid (content and form, maximum 240 points per case).</div></div><div><h3>Results</h3><div>Overall performance was judged to be equivalent to that of a final-year student. Generalist models outperformed specialist models (12.45<!--> <!-->±<!--> <!-->3.59 vs. 10.88<!--> <!-->±<!--> <!-->3.75; <em>P</em> <!-->&lt;<!--> <!-->0.001; r<!--> <!-->=<!--> <!-->0.22). Form scores consistently exceeded content scores (mean difference: 1.40 points). Hallucinations were consistently identified.</div></div><div><h3>Conclusions</h3><div>Specialised LLMs do not currently offer any advantage in clinical reasoning. The quality of the responses’ wording, which is superior to their clinical substance, may foster overconfidence in users. These results call for rigorous supervision of the use of LLMs in veterinary medicine.</div></div><div><h3>Propos</h3><div>Les grands modèles de langage (LLM) sont désormais utilisés en pratique vétérinaire, mais leurs capacités de raisonnement clinique restent mal évaluées dans ce contexte.</div></div><div><h3>Matériel et méthodes</h3><div>Dix LLM (six généralistes, quatre spécialisés en médecine vétérinaire) ont été comparés sur dix cas cliniques authentiques couvrant huit spécialités. Des vétérinaires spécialistes certifiés, en aveugle, ont évalué les réponses selon une grille structurée en six dimensions (contenu et forme, maximum 240 points/cas).</div></div><div><h3>Résultats</h3><div>Les performances globales sont jugées équivalentes à celles d’un étudiant en dernière année. Les modèles généralistes surpassent les modèles spécialisés (12,45<!--> <!-->±<!--> <!-->3,59 vs 10,88<!--> <!-->±<!--> <!-->3,75 ; <em>p</em> <!-->&lt;<!--> <!-->0,001 ; r<!--> <!-->=<!--> <!-->0,22). Les scores de forme excèdent systématiquement ceux de contenu (différence moyenne : 1,40 point). Des hallucinations ont systématiquement été recensées.</div></div><div><h3>Conclusions</h3><div>Les LLM spécialisés ne confèrent à ce jour pas d’avantage en raisonnement clinique. La qualité de rédaction des réponses, supérieure au fond clinique, représente un risque d’excès de confiance par les utilisateurs. Ces résultats appellent à un encadrement rigoureux de l’usage des LLM en médecine vétérinaire.</div></div>","PeriodicalId":38077,"journal":{"name":"Revue Veterinaire Clinique","volume":"61 3","pages":"Pages 119-129"},"PeriodicalIF":0.0,"publicationDate":"2026-08-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"148646815","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}