Preventive Medicine Reports最新文献

{"title":"Behavioral economics, lifestyle, and health-related factors associated with participation in breast and cervical cancer screenings: A cross-sectional analysis of Japanese women","authors":"Miho Satoh ,&nbsp;Naoko Sato ,&nbsp;Mizuki Sekino","doi":"10.1016/j.pmedr.2025.103249","DOIUrl":"10.1016/j.pmedr.2025.103249","url":null,"abstract":"<div><h3>Objective</h3><div>This study investigated factors influencing Japanese women's participation in breast and cervical cancer screenings, with a focus on health behaviors, behavioral economics characteristics, socioeconomic status, and physical and mental health.</div></div><div><h3>Methods</h3><div>Using secondary data from the Japan Household Panel Survey (Wave 2021, collected February 2021), we analyzed responses from 410 women aged ≤70 years. Key variables included risk aversion, time preference, exercise frequency, smoking status, alcohol consumption, nutritional intake, subjective and mental health, body mass index, and sociodemographic factors such as education, employment, and municipality type.</div></div><div><h3>Results</h3><div>The participants' mean age was 52.92 years (standard deviation = 9.17 years). Of the women, 15.9 % underwent cervical cancer screening and 16.8 % underwent breast cancer screening. A logistic regression analysis revealed that, for both breast and cervical cancer screenings, high psychological distress, risk aversion, and smoking were associated with lower participation, whereas regular exercise, permanent employment, and residence in towns and villages were associated with higher participation. Smoking was significantly associated with breast cancer screening participation, and utilization of medical services was significantly associated with cervical cancer screening participation.</div></div><div><h3>Conclusion</h3><div>Interventions incorporating behavioral economics approaches, such as addressing risk perception and promoting health behaviors, may enhance Japanese women's cancer screening participation.</div></div>","PeriodicalId":38066,"journal":{"name":"Preventive Medicine Reports","volume":"59 ","pages":"Article 103249"},"PeriodicalIF":2.4,"publicationDate":"2025-09-15","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145098669","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Feasibility and preliminary effectiveness of a patient-centered self-care intervention for adults with coronary heart disease in a low resource setting","authors":"Rukhsana Perveen ,&nbsp;Muhammad Saqib Rabbani ,&nbsp;Samina Kausar ,&nbsp;Kainat Asmat","doi":"10.1016/j.pmedr.2025.103246","DOIUrl":"10.1016/j.pmedr.2025.103246","url":null,"abstract":"<div><h3>Objective</h3><div>Coronary heart disease (CHD) remains a leading cause of global morbidity and mortality, with disproportionate impact in low resource contexts. Despite the importance of effective self-care in improving outcomes, existing interventions are often fragmented, disease-focused, and lack contextual relevance. This study aimed to evaluate the feasibility and preliminary effectiveness of a nurse-led, patient-centered self-care intervention (PCSI) for individuals with CHD in Pakistan.</div></div><div><h3>Methods</h3><div>A mixed-methods study was conducted between May 17 to August 16, 2024 in inpatient department of public hospital in Pakistan. The intervention, developed through literature review and stakeholder input, involved a 2-h individualized education and counselling session delivered one day before discharge. Effectiveness was evaluated using a one-group pretest-posttest design, assessing self-efficacy and self-care behaviors at baseline and four weeks post-discharge. Feasibility was explored through post-intervention interviews with 12 participants. Quantitative data were analyzed using descriptive statistics and Wilcoxon signed-rank test in SPSS, while qualitative data were analyzed manually through content analysis.</div></div><div><h3>Results</h3><div>Thirty-seven participants (mean age 50.67 ± 6.04 years; 32 men) completed the study. Self-efficacy improved significantly, with mean scores increasing from 76.75 ± 19.65 to 99.86 ± 0.82 (Z = −4.864, <em>p</em> &lt; 0.001). Significant improvements were observed in self-care behaviors across all domains (p &lt; 0.001). Qualitative findings confirmed the intervention's feasibility, relevance and acceptability, while suggesting family engagement, and ongoing support.</div></div><div><h3>Conclusion</h3><div>The PCSI demonstrated promising effectiveness and feasibility, supporting its potential integration into routine care. Future adaptations could enhance sustained self-care and clinical outcomes in low-resource settings.</div></div>","PeriodicalId":38066,"journal":{"name":"Preventive Medicine Reports","volume":"59 ","pages":"Article 103246"},"PeriodicalIF":2.4,"publicationDate":"2025-09-15","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145098662","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Glucagon-like peptide-1 receptor agonists and suicide risk in individuals with diabetes and Cannabis use disorder","authors":"Yesh Dhruva ,&nbsp;Erick Messias ,&nbsp;Ping-I Lin","doi":"10.1016/j.pmedr.2025.103244","DOIUrl":"10.1016/j.pmedr.2025.103244","url":null,"abstract":"<div><h3>Objective</h3><div>The current study is to examine the association between GLP-1 receptor agonist (GLP-1 RA) use and suicide attempt risk in individuals with type 2 diabetes mellitus (T2DM), including those with comorbid cannabis use disorder (CUD).</div></div><div><h3>Methods</h3><div>We conducted a retrospective study using the TriNetX Research Network. Adults aged 30–85 years with a diagnosis of T2DM were categorized by GLP-1 RA exposure and CUD sourced from over 20 countries across the Americas, Europe-Middle East-Africa, and Asia-Pacific from 2003 to 2023. Individuals with a prior diagnosis of suicidal ideation were excluded. The primary outcome was a new diagnosis of suicide attempt within one year. Cox proportional hazards models were used to estimate adjusted hazard ratios (aHRs), controlling for age, sex, depression, body mass index, and glycated hemoglobin A1c (HbA1c) levels. Kaplan-Meier curves were used to visualize cumulative risk.</div></div><div><h3>Results</h3><div>Among 6,424,228 individuals with T2DM, GLP-1 RA use was associated with significantly lower risk of suicide attempt compared to unexposed individuals (aHR: 0.63; 95 % CI: 0.47,0.85). In contrast, patients with CUD exhibited markedly elevated risk (aHR: 5.50; 95 % CI: 4.39,6.89). This elevated risk persisted among those concurrently using GLP-1 RAs and diagnosed with CUD (aHR: 5.75; 95 % CI: 3.42,9.69). No significant risk reduction was observed among CUD patients using GLP-1 RAs compared to those not using them (aHR: 1.00; 95 % CI 0.37–2.69).</div></div><div><h3>Conclusions</h3><div>The inverse association between GLP-1 RAs and suicide attempt was attenuated among cannabis users. These findings underscore the importance of addressing substance use when assessing psychiatric risk in diabetes care.</div></div>","PeriodicalId":38066,"journal":{"name":"Preventive Medicine Reports","volume":"58 ","pages":"Article 103244"},"PeriodicalIF":2.4,"publicationDate":"2025-09-12","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145049278","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Learning needs and experiences of hospital nurses in genetic medicine in a rural area of Japan: A cross-sectional questionnaire survey in Oita prefecture","authors":"Nobue Tsukatani ,&nbsp;Yumi Shimada ,&nbsp;Masanori Inoue ,&nbsp;Akiko Hatanaka ,&nbsp;Shizuyo Tominaga ,&nbsp;Kenji Ihara","doi":"10.1016/j.pmedr.2025.103239","DOIUrl":"10.1016/j.pmedr.2025.103239","url":null,"abstract":"<div><div><em>Objective:</em> This study aimed to investigate hospital nurses' experiences in providing care to patients with genetic diseases and their families and to identify their educational needs regarding genetic medicine and genetic counseling in Oita Prefecture, a representative rural region of Japan.</div><div><em>Methods:</em> This cross-sectional questionnaire survey was conducted at ten cancer treatment hospitals in Oita Prefecture, including two central hospitals for cancer genomic medicine and eight regional hospitals, from October 11, 2021 to January 20, 2022. Of 1881 invited nurses, 1001 valid responses were analyzed. Data were collected using an anonymous self-administered questionnaire covering demographics, understanding of genetic terms, care experiences, and learning needs.</div><div><em>Results:</em> The respondents showed limited understanding of clinical genetics terminology, with fewer than 5 % having received genetics-related training. Only 8.6 % had experience in caring for patients and their families concerns about genetic diseases, and over 80 % of those felt inadequate. More than 70 % expressed a strong desire to learn about genetic medicine.</div><div><em>Conclusions:</em> Hospital nurses in rural Japan have significant learning needs in genetic medicine and genetic counseling. Educational programs tailored to regional backgrounds, along with collaboration with clinical genetic specialists, especially certified genetic counselors, could contribute to ensuring equitable and high-quality genetic healthcare service.</div></div>","PeriodicalId":38066,"journal":{"name":"Preventive Medicine Reports","volume":"59 ","pages":"Article 103239"},"PeriodicalIF":2.4,"publicationDate":"2025-09-12","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145108252","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Human papillomavirus awareness in a digital world: The intersection of faith and online media","authors":"Alfu Laily ,&nbsp;Soojung Jo ,&nbsp;Robert J. Duncan ,&nbsp;Randolph D. Hubach ,&nbsp;Kathryn J. LaRoche ,&nbsp;Natalia M. Rodriguez ,&nbsp;Monica L. Kasting","doi":"10.1016/j.pmedr.2025.103241","DOIUrl":"10.1016/j.pmedr.2025.103241","url":null,"abstract":"<div><div>Objective: This study examines the association between Human Papillomavirus (HPV) awareness and internet use, social media use, and trust in health information from religious leaders.</div><div>Methods: We analyzed national data, collected March–November 2022 in the U.S. The final sample included 3444 adults ages 18–65 years. The outcome was HPV awareness (being aware of both HPV and the HPV vaccine). Weighted chi square and multivariable logistics regression were used to assess the outcome and each predictor, including internet and social media use, trust in health information from religious leaders, and demographic factors.</div><div>Results: Among respondents, 62.3 % were aware of HPV. Those who used the internet had higher odds of HPV awareness (aOR = 2.31, 95 %CI = 1.58,3.39), whereas those reporting perceived online health information from social media as accurate had lower odds of HPV awareness (aOR = 0.40, 95 %CI = 0.16,0.98). Social media use and trust in health information from religious leaders were not significantly associated with HPV awareness.</div><div>Conclusion: Internet use, but not social media use or trust in health information from religious leaders, may improve HPV awareness. This highlights the need for interventions to guide individuals find reliable sources online and for future research to assess accuracy of online HPV information to facilitate vaccination decisions.</div></div>","PeriodicalId":38066,"journal":{"name":"Preventive Medicine Reports","volume":"58 ","pages":"Article 103241"},"PeriodicalIF":2.4,"publicationDate":"2025-09-12","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145060237","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Inequalities in breast cancer incidence and mortality in women with and without disabilities in South Korea: A population-based cohort study","authors":"Hee-Yeon Kang ,&nbsp;Eunjung Park ,&nbsp;Thi Tra Bui ,&nbsp;Byungmi Kim ,&nbsp;Jin-Kyoung Oh","doi":"10.1016/j.pmedr.2025.103242","DOIUrl":"10.1016/j.pmedr.2025.103242","url":null,"abstract":"<div><h3>Objective</h3><div>Women with disabilities often face functional limitations and comorbidities that increase cancer risk. This study investigated breast cancer incidence and mortality among women with and without disabilities in South Korea.</div></div><div><h3>Methods</h3><div>We analyzed 2.87 million cancer-free women aged ≥30 who participated in the 2002–2003 national health screening program, linking the National Health Insurance Database, Cancer Registry, and cause-of-death records (2003–2019). Standardized incidence ratios (SIRs), standardized mortality ratios (SMRs), and mortality-to-incidence (M/I) ratios were calculated by disability status. Cox proportional hazards models with piecewise follow-up estimated adjusted hazard ratios (aHRs) for breast cancer outcomes.</div></div><div><h3>Results</h3><div>Among 296,689 women with disabilities, 3579 developed breast cancer and 465 died from it; among 2.58 million without disabilities, 46,267 developed it and 3779 died. Women with disabilities had lower incidence (SIR ratio 0.86, 95 % CI 0.83, 0.90) but comparable breast cancer-specific mortality (SMR ratio 1.00, 95 % CI 0.89, 1.13). Cox models showed consistently lower aHRs for breast cancer incidence and mortality early on, but aHRs for all-cause mortality increased over time.</div></div><div><h3>Conclusions</h3><div>Despite lower incidence, women with disabilities experienced similar breast cancer-specific mortality and higher long-term all-cause mortality. These findings underscore persistent inequalities and highlight the need for timely, equitable cancer care.</div></div>","PeriodicalId":38066,"journal":{"name":"Preventive Medicine Reports","volume":"59 ","pages":"Article 103242"},"PeriodicalIF":2.4,"publicationDate":"2025-09-12","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145098663","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"A pilot study of high-intensity interval training and continuous positive airway pressure on vascular health in Thai adults with obesity, obstructive sleep apnea, and type 2 diabetes","authors":"Kanpiraya Nithitsutthibuta ,&nbsp;Sureeporn Uthaikhup ,&nbsp;Nuntigar Sonsuwan ,&nbsp;Jaruta Kunritt ,&nbsp;Khajornsak Tragoolpua ,&nbsp;Arisa Parameyong ,&nbsp;Pongson Yaicharoen ,&nbsp;Sainatee Pratanaphon","doi":"10.1016/j.pmedr.2025.103238","DOIUrl":"10.1016/j.pmedr.2025.103238","url":null,"abstract":"<div><h3>Objective</h3><div>This pilot study compared the effects of high-intensity interval training (HIIT) and continuous positive airway pressure (CPAP) on vascular health in Thai adults with obesity, obstructive sleep apnea (OSA), and type 2 diabetes mellitus.</div></div><div><h3>Methods</h3><div>Participants were recruited from a university hospital in Chiang Mai, Thailand (July 2023–April 2024). Thirty participants were age-matched and sequentially assigned to CPAP, HIIT, or usual care groups. The HIIT group completed four 4-min treadmill intervals at 85 %–95 % of maximum heart rate, three times weekly for 12 weeks. The CPAP group used CPAP ≥ four hours/night. Primary outcomes were flow-mediated dilation (FMD) and carotid intima-media thickness (CIMT). Secondary outcomes included sleep indices, blood biomarkers, and body composition.</div></div><div><h3>Results</h3><div>Adherence was high in both HIIT (97.78 %) and CPAP (95.89 %) groups. The HIIT group showed lower CIMT than controls (<em>p</em> = 0.05) and improved FMD and CIMT from baseline (<em>p</em> &lt; 0.01). Both HIIT and CPAP groups reduced apnea-hypopnea index and body mass index compared with controls and baseline (<em>p</em> ≤ 0.01). Only the CPAP group improved oxygen saturation (p ≤ 0.01). No significant changes were observed in blood biomarkers (<em>p</em> &gt; 0.05).</div></div><div><h3>Conclusions</h3><div>HIIT may benefit vascular health and OSA severity. Both HIIT and CPAP improved body mass index. Larger trials are warranted.</div></div>","PeriodicalId":38066,"journal":{"name":"Preventive Medicine Reports","volume":"58 ","pages":"Article 103238"},"PeriodicalIF":2.4,"publicationDate":"2025-09-11","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145049275","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Socioeconomic inequalities in waist circumference and its 12-year change: Moderation by neighbourhood population density","authors":"Sungkavi Selvakumaran ,&nbsp;Manoj Chandrabose ,&nbsp;Nyssa Hadgraft ,&nbsp;Neville Owen ,&nbsp;Takemi Sugiyama","doi":"10.1016/j.pmedr.2025.103236","DOIUrl":"10.1016/j.pmedr.2025.103236","url":null,"abstract":"<div><h3>Objective</h3><div>Reducing socioeconomic inequalities in obesity is a public health priority. We examined whether population density, a key environmental characteristic associated with obesity, moderates the associations of area-level socioeconomic status (SES) with waist circumference and its rate of change.</div></div><div><h3>Methods</h3><div>Data from adults in an Australian national study, collected across three waves (1999–2000, 2005–06, 2011–12), were used. Outcomes were objectively measured baseline waist circumference (<em>N</em> = 4835) and its rate of change (<em>N</em> = 1158). Exposure was baseline area-level SES. Baseline population density was calculated within a 1 km buffer around residences. Multilevel regression models were used.</div></div><div><h3>Results</h3><div>Higher area-level SES was associated with smaller baseline waist circumference (−1.45, 95 % CI [−2.28, −0.12]) but not with change over time (0.04, 95 % CI [−0.02, 0.09]). In stratified cross-sectional analyses, this association was significant in lower- (−5.00, 95 % CI -7.73, −2.28]) and medium-density (−2.61, 95 % CI [−4.55, −0.67]), but not in higher-density areas (−0.54, 95 % CI [−1.73,0.65]). In longitudinal analyses, lower SES was linked to smaller increases in waist circumference in lower- (0.16, 95 % CI [0.03, 0.29]) and medium-density (0.17, 95 % CI [0.05, 0.30]) areas, suggesting a narrowing of socioeconomic inequalities in obesity. However, annual changes were modest and unlikely to offset baseline inequalities.</div></div><div><h3>Conclusions</h3><div>Population density moderated associations of area-level SES with waist circumference and its change. Inequalities in baseline obesity were pronounced in lower density areas but not higher density areas. While the longitudinal findings of the moderation patterns were different from baseline results, they suggest persistent socioeconomic inequalities in obesity in lower density areas.</div></div>","PeriodicalId":38066,"journal":{"name":"Preventive Medicine Reports","volume":"59 ","pages":"Article 103236"},"PeriodicalIF":2.4,"publicationDate":"2025-09-11","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145098665","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Global prevalence of barriers and facilitators to physical activity in children and adolescents: A systematic review with meta-analysis","authors":"Bruno Oliveira Amorim Sampaio ,&nbsp;Armando Rodrigues de Alencar Santos ,&nbsp;Marcus Vinícius Nascimento-Ferreira ,&nbsp;Augusto César Ferreira De Moraes","doi":"10.1016/j.pmedr.2025.103230","DOIUrl":"10.1016/j.pmedr.2025.103230","url":null,"abstract":"<div><h3>Objectives</h3><div>This study systematically reviewed the literature on the prevalence of barriers and facilitators to physical activity in children and adolescents and provided global prevalence estimates through meta-analysis.</div></div><div><h3>Methods</h3><div>Articles published in PubMed (1966–), Scopus (1970–), and Web of Science (1900–) were searched from database inception through May 30, 2024. The search was conducted between May 15 and May 30, 2024. Sixteen studies were included, with 14 pooled for adolescents and 2 for children. The protocol was registered in PROSPERO (ID: CRD42024512962).</div></div><div><h3>Results</h3><div>In children, the prevalence of barriers to physical activity ranged from 12 % to 26 %, with a pooled prevalence of 23 % (95 % CI, 19 %, 27 %). Facilitators in children ranged from 12 % to 33 %, with a pooled prevalence of 28 % (95 % CI, 24 %, 33 %). Among adolescents, barriers ranged from 3 % to 65 %, with a pooled prevalence of 32 % (95 % CI, 20 %, 44 %). Facilitators in adolescents ranged from 9 % to 21 %, with a pooled prevalence of 10 % (95 % CI, 8 %, 11 %).</div></div><div><h3>Conclusions</h3><div>Barriers are more prevalent in adolescents, while facilitators are more prevalent in children. These findings highlight the need for targeted interventions and reveal research gaps, particularly regarding barriers in children and facilitators in adolescents.</div></div>","PeriodicalId":38066,"journal":{"name":"Preventive Medicine Reports","volume":"58 ","pages":"Article 103230"},"PeriodicalIF":2.4,"publicationDate":"2025-09-10","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145049272","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Disentangling unobserved heterogeneity: Novel application of a statistical method to evaluate a multilevel healthcare intervention for hispanic individuals living on the United States-Mexico border with comorbid diabetes and hypertension","authors":"MinJae Lee ,&nbsp;Juliana Z. Lopez ,&nbsp;Natalia I. Heredia ,&nbsp;Maria Zolezzi ,&nbsp;Soo Kyung Park ,&nbsp;Paul G. Yeh ,&nbsp;Lisa Mitchell-Bennett ,&nbsp;Belinda M. Reininger","doi":"10.1016/j.pmedr.2025.103237","DOIUrl":"10.1016/j.pmedr.2025.103237","url":null,"abstract":"<div><h3>Objective</h3><div>Individuals with diabetes and hypertension represent a high-risk population with poor prognosis and high healthcare costs. Clinicians recognize the complexities of treating patients with multiple chronic conditions; however, the research literature shows little attention to characterizing change patterns in hypertension outcomes for participants of health interventions. The aim of this study was to characterize individual-level longitudinal trajectories of heterogeneity in blood pressure among a Hispanic population with uncontrolled type II diabetes and hypertension enrolled in a multi-level intervention.</div></div><div><h3>Methods</h3><div>This study was implemented along the US-Mexico border. Using blood pressure results collected longitudinally between 2013 and 2020 from 2476 participants with diabetes and high blood pressure at baseline, we conducted group-based trajectory modeling to identify latent groups for systolic blood pressure (SBP). We evaluated participant engagement characteristics and other individual-level characteristics and elucidated how these factors were associated with group membership.</div></div><div><h3>Results</h3><div>We identified four distinct SBP trajectory groups. Three groups demonstrated improvement, two of which had clinically significant changes in SBP that were maintained through 24 months. One group was resistant to SBP improvements despite the intervention. While all groups maintained higher than normal SBP levels, the group characteristics elucidate factors that contribute to improvement or lack thereof.</div></div><div><h3>Conclusion</h3><div>Understanding SBP trajectories in the context of population heterogeneity can inform tailoring approaches undertaken by interventions. These findings inform approaches for clinics to more effectively match screening of non-medical drivers of health to individual patient needs.</div></div>","PeriodicalId":38066,"journal":{"name":"Preventive Medicine Reports","volume":"58 ","pages":"Article 103237"},"PeriodicalIF":2.4,"publicationDate":"2025-09-08","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145027007","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}