Preventive Medicine Reports最新文献

{"title":"Inequalities in breast cancer incidence and mortality in women with and without disabilities in South Korea: A population-based cohort study","authors":"Hee-Yeon Kang ,&nbsp;Eunjung Park ,&nbsp;Thi Tra Bui ,&nbsp;Byungmi Kim ,&nbsp;Jin-Kyoung Oh","doi":"10.1016/j.pmedr.2025.103242","DOIUrl":"10.1016/j.pmedr.2025.103242","url":null,"abstract":"<div><h3>Objective</h3><div>Women with disabilities often face functional limitations and comorbidities that increase cancer risk. This study investigated breast cancer incidence and mortality among women with and without disabilities in South Korea.</div></div><div><h3>Methods</h3><div>We analyzed 2.87 million cancer-free women aged ≥30 who participated in the 2002–2003 national health screening program, linking the National Health Insurance Database, Cancer Registry, and cause-of-death records (2003–2019). Standardized incidence ratios (SIRs), standardized mortality ratios (SMRs), and mortality-to-incidence (M/I) ratios were calculated by disability status. Cox proportional hazards models with piecewise follow-up estimated adjusted hazard ratios (aHRs) for breast cancer outcomes.</div></div><div><h3>Results</h3><div>Among 296,689 women with disabilities, 3579 developed breast cancer and 465 died from it; among 2.58 million without disabilities, 46,267 developed it and 3779 died. Women with disabilities had lower incidence (SIR ratio 0.86, 95 % CI 0.83, 0.90) but comparable breast cancer-specific mortality (SMR ratio 1.00, 95 % CI 0.89, 1.13). Cox models showed consistently lower aHRs for breast cancer incidence and mortality early on, but aHRs for all-cause mortality increased over time.</div></div><div><h3>Conclusions</h3><div>Despite lower incidence, women with disabilities experienced similar breast cancer-specific mortality and higher long-term all-cause mortality. These findings underscore persistent inequalities and highlight the need for timely, equitable cancer care.</div></div>","PeriodicalId":38066,"journal":{"name":"Preventive Medicine Reports","volume":"59 ","pages":"Article 103242"},"PeriodicalIF":2.4,"publicationDate":"2025-09-12","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145098663","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"A pilot study of high-intensity interval training and continuous positive airway pressure on vascular health in Thai adults with obesity, obstructive sleep apnea, and type 2 diabetes","authors":"Kanpiraya Nithitsutthibuta ,&nbsp;Sureeporn Uthaikhup ,&nbsp;Nuntigar Sonsuwan ,&nbsp;Jaruta Kunritt ,&nbsp;Khajornsak Tragoolpua ,&nbsp;Arisa Parameyong ,&nbsp;Pongson Yaicharoen ,&nbsp;Sainatee Pratanaphon","doi":"10.1016/j.pmedr.2025.103238","DOIUrl":"10.1016/j.pmedr.2025.103238","url":null,"abstract":"<div><h3>Objective</h3><div>This pilot study compared the effects of high-intensity interval training (HIIT) and continuous positive airway pressure (CPAP) on vascular health in Thai adults with obesity, obstructive sleep apnea (OSA), and type 2 diabetes mellitus.</div></div><div><h3>Methods</h3><div>Participants were recruited from a university hospital in Chiang Mai, Thailand (July 2023–April 2024). Thirty participants were age-matched and sequentially assigned to CPAP, HIIT, or usual care groups. The HIIT group completed four 4-min treadmill intervals at 85 %–95 % of maximum heart rate, three times weekly for 12 weeks. The CPAP group used CPAP ≥ four hours/night. Primary outcomes were flow-mediated dilation (FMD) and carotid intima-media thickness (CIMT). Secondary outcomes included sleep indices, blood biomarkers, and body composition.</div></div><div><h3>Results</h3><div>Adherence was high in both HIIT (97.78 %) and CPAP (95.89 %) groups. The HIIT group showed lower CIMT than controls (<em>p</em> = 0.05) and improved FMD and CIMT from baseline (<em>p</em> &lt; 0.01). Both HIIT and CPAP groups reduced apnea-hypopnea index and body mass index compared with controls and baseline (<em>p</em> ≤ 0.01). Only the CPAP group improved oxygen saturation (p ≤ 0.01). No significant changes were observed in blood biomarkers (<em>p</em> &gt; 0.05).</div></div><div><h3>Conclusions</h3><div>HIIT may benefit vascular health and OSA severity. Both HIIT and CPAP improved body mass index. Larger trials are warranted.</div></div>","PeriodicalId":38066,"journal":{"name":"Preventive Medicine Reports","volume":"58 ","pages":"Article 103238"},"PeriodicalIF":2.4,"publicationDate":"2025-09-11","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145049275","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Socioeconomic inequalities in waist circumference and its 12-year change: Moderation by neighbourhood population density","authors":"Sungkavi Selvakumaran ,&nbsp;Manoj Chandrabose ,&nbsp;Nyssa Hadgraft ,&nbsp;Neville Owen ,&nbsp;Takemi Sugiyama","doi":"10.1016/j.pmedr.2025.103236","DOIUrl":"10.1016/j.pmedr.2025.103236","url":null,"abstract":"<div><h3>Objective</h3><div>Reducing socioeconomic inequalities in obesity is a public health priority. We examined whether population density, a key environmental characteristic associated with obesity, moderates the associations of area-level socioeconomic status (SES) with waist circumference and its rate of change.</div></div><div><h3>Methods</h3><div>Data from adults in an Australian national study, collected across three waves (1999–2000, 2005–06, 2011–12), were used. Outcomes were objectively measured baseline waist circumference (<em>N</em> = 4835) and its rate of change (<em>N</em> = 1158). Exposure was baseline area-level SES. Baseline population density was calculated within a 1 km buffer around residences. Multilevel regression models were used.</div></div><div><h3>Results</h3><div>Higher area-level SES was associated with smaller baseline waist circumference (−1.45, 95 % CI [−2.28, −0.12]) but not with change over time (0.04, 95 % CI [−0.02, 0.09]). In stratified cross-sectional analyses, this association was significant in lower- (−5.00, 95 % CI -7.73, −2.28]) and medium-density (−2.61, 95 % CI [−4.55, −0.67]), but not in higher-density areas (−0.54, 95 % CI [−1.73,0.65]). In longitudinal analyses, lower SES was linked to smaller increases in waist circumference in lower- (0.16, 95 % CI [0.03, 0.29]) and medium-density (0.17, 95 % CI [0.05, 0.30]) areas, suggesting a narrowing of socioeconomic inequalities in obesity. However, annual changes were modest and unlikely to offset baseline inequalities.</div></div><div><h3>Conclusions</h3><div>Population density moderated associations of area-level SES with waist circumference and its change. Inequalities in baseline obesity were pronounced in lower density areas but not higher density areas. While the longitudinal findings of the moderation patterns were different from baseline results, they suggest persistent socioeconomic inequalities in obesity in lower density areas.</div></div>","PeriodicalId":38066,"journal":{"name":"Preventive Medicine Reports","volume":"59 ","pages":"Article 103236"},"PeriodicalIF":2.4,"publicationDate":"2025-09-11","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145098665","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Global prevalence of barriers and facilitators to physical activity in children and adolescents: A systematic review with meta-analysis","authors":"Bruno Oliveira Amorim Sampaio ,&nbsp;Armando Rodrigues de Alencar Santos ,&nbsp;Marcus Vinícius Nascimento-Ferreira ,&nbsp;Augusto César Ferreira De Moraes","doi":"10.1016/j.pmedr.2025.103230","DOIUrl":"10.1016/j.pmedr.2025.103230","url":null,"abstract":"<div><h3>Objectives</h3><div>This study systematically reviewed the literature on the prevalence of barriers and facilitators to physical activity in children and adolescents and provided global prevalence estimates through meta-analysis.</div></div><div><h3>Methods</h3><div>Articles published in PubMed (1966–), Scopus (1970–), and Web of Science (1900–) were searched from database inception through May 30, 2024. The search was conducted between May 15 and May 30, 2024. Sixteen studies were included, with 14 pooled for adolescents and 2 for children. The protocol was registered in PROSPERO (ID: CRD42024512962).</div></div><div><h3>Results</h3><div>In children, the prevalence of barriers to physical activity ranged from 12 % to 26 %, with a pooled prevalence of 23 % (95 % CI, 19 %, 27 %). Facilitators in children ranged from 12 % to 33 %, with a pooled prevalence of 28 % (95 % CI, 24 %, 33 %). Among adolescents, barriers ranged from 3 % to 65 %, with a pooled prevalence of 32 % (95 % CI, 20 %, 44 %). Facilitators in adolescents ranged from 9 % to 21 %, with a pooled prevalence of 10 % (95 % CI, 8 %, 11 %).</div></div><div><h3>Conclusions</h3><div>Barriers are more prevalent in adolescents, while facilitators are more prevalent in children. These findings highlight the need for targeted interventions and reveal research gaps, particularly regarding barriers in children and facilitators in adolescents.</div></div>","PeriodicalId":38066,"journal":{"name":"Preventive Medicine Reports","volume":"58 ","pages":"Article 103230"},"PeriodicalIF":2.4,"publicationDate":"2025-09-10","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145049272","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Disentangling unobserved heterogeneity: Novel application of a statistical method to evaluate a multilevel healthcare intervention for hispanic individuals living on the United States-Mexico border with comorbid diabetes and hypertension","authors":"MinJae Lee ,&nbsp;Juliana Z. Lopez ,&nbsp;Natalia I. Heredia ,&nbsp;Maria Zolezzi ,&nbsp;Soo Kyung Park ,&nbsp;Paul G. Yeh ,&nbsp;Lisa Mitchell-Bennett ,&nbsp;Belinda M. Reininger","doi":"10.1016/j.pmedr.2025.103237","DOIUrl":"10.1016/j.pmedr.2025.103237","url":null,"abstract":"<div><h3>Objective</h3><div>Individuals with diabetes and hypertension represent a high-risk population with poor prognosis and high healthcare costs. Clinicians recognize the complexities of treating patients with multiple chronic conditions; however, the research literature shows little attention to characterizing change patterns in hypertension outcomes for participants of health interventions. The aim of this study was to characterize individual-level longitudinal trajectories of heterogeneity in blood pressure among a Hispanic population with uncontrolled type II diabetes and hypertension enrolled in a multi-level intervention.</div></div><div><h3>Methods</h3><div>This study was implemented along the US-Mexico border. Using blood pressure results collected longitudinally between 2013 and 2020 from 2476 participants with diabetes and high blood pressure at baseline, we conducted group-based trajectory modeling to identify latent groups for systolic blood pressure (SBP). We evaluated participant engagement characteristics and other individual-level characteristics and elucidated how these factors were associated with group membership.</div></div><div><h3>Results</h3><div>We identified four distinct SBP trajectory groups. Three groups demonstrated improvement, two of which had clinically significant changes in SBP that were maintained through 24 months. One group was resistant to SBP improvements despite the intervention. While all groups maintained higher than normal SBP levels, the group characteristics elucidate factors that contribute to improvement or lack thereof.</div></div><div><h3>Conclusion</h3><div>Understanding SBP trajectories in the context of population heterogeneity can inform tailoring approaches undertaken by interventions. These findings inform approaches for clinics to more effectively match screening of non-medical drivers of health to individual patient needs.</div></div>","PeriodicalId":38066,"journal":{"name":"Preventive Medicine Reports","volume":"58 ","pages":"Article 103237"},"PeriodicalIF":2.4,"publicationDate":"2025-09-08","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145027007","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Knowledge, attitude, and practice towards postmenopausal osteoporosis among postmenopausal women: A cross-sectional study","authors":"Feng Xiong ,&nbsp;Aoqi Zang ,&nbsp;Zhe Xu ,&nbsp;Qingyi Cao ,&nbsp;Ziquan Shen ,&nbsp;Feng Qian ,&nbsp;Hui Xu","doi":"10.1016/j.pmedr.2025.103234","DOIUrl":"10.1016/j.pmedr.2025.103234","url":null,"abstract":"<div><h3>Objective</h3><div>Postmenopausal osteoporosis, affecting 33 % of women over 60 in China, increases fracture risks and significantly impacts quality of life. This condition leads to physical disability and psychological distress, underscoring the need for targeted interventions. This study aimed to assess the knowledge, attitude, and practice (KAP) of postmenopausal women concerning postmenopausal osteoporosis and explore associated factors.</div></div><div><h3>Methods</h3><div>A cross-sectional study was conducted from June 29 to September 8, 2024, at the First People's Hospital of Bengbu City using a self-administered questionnaire to assess KAP, and data were analyzed using descriptive statistics and nonparametric tests.</div></div><div><h3>Results</h3><div>A total of 459 valid participants in the study, of whom 166 (36.17 %) were diagnosed with postmenopausal osteoporosis. Among those diagnosed with osteoporosis, 65 (39.16 %) received systematic treatment. The mean scores for knowledge, attitude, and practice were 10.03 ± 5.47 (range: 0–28), 28.03 ± 3.07 (range: 8–40), and 21.87 ± 5.10 (range: 7–35), respectively.</div></div><div><h3>Conclusion</h3><div>While postmenopausal women demonstrated insufficient knowledge and inadequate practices, targeted educational efforts may help improve osteoporosis-related behaviors and outcomes. These findings highlight the need for targeted educational interventions to improve osteoporosis-related knowledge and encourage proactive behaviors in managing the disease.</div></div>","PeriodicalId":38066,"journal":{"name":"Preventive Medicine Reports","volume":"58 ","pages":"Article 103234"},"PeriodicalIF":2.4,"publicationDate":"2025-09-08","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145049274","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Factors associated with healthcare personnel uptake of updated COVID-19 vaccine doses in the United States","authors":"Eric Kontowicz ,&nbsp;Kari K. Harland ,&nbsp;Amy Stubbs ,&nbsp;David Beiser ,&nbsp;Ian Plumb ,&nbsp;Anusha Krishnadasan ,&nbsp;David A. Talan ,&nbsp;Nicholas M. Mohr","doi":"10.1016/j.pmedr.2025.103233","DOIUrl":"10.1016/j.pmedr.2025.103233","url":null,"abstract":"<div><h3>Objective</h3><div>Evaluate factors associated with United States (US) healthcare personnel (HCP) uptake of an updated COVID-19 vaccine.</div></div><div><h3>Methods</h3><div>We analyzed data from 887 US HCP enrolled between September 25, 2023, and April 17, 2024, in a multisite case-control COVID-19 vaccine effectiveness study. Sociodemographic and attitudinal data were collected via standardized surveys, and vaccination status was verified using source documentation.</div></div><div><h3>Results</h3><div>Overall, 188 (21.2 %) HCP received the updated vaccine. HCP aged 50–64 years (adjusted odds ratio [aOR] 2.02, 95 % CI: 1.11–3.67) versus ages 18–29, and HCP with undergraduate (aOR 3.75, 95 % CI: 1.97–7.12) or graduate degrees (aOR 7.73, 95 % CI: 4.10–14.55) versus high school/some college had higher odds of vaccination. Nurses and nurse assistants had lower odds (aOR 0.48, 95 % CI: 0.30–0.76) versus other job roles. Vaccinated HCP were more likely than unvaccinated HCP to cite concerns about personal infection (89.9 % vs. 44.6 %), infecting family/friends (96.3 % vs. 56.0 %), vaccine availability (63.3 % vs. 18.9 %), and peer-reviewed literature (56.4 % vs. 28.3 %) as important influences. These factors remained consistent with findings from a prior vaccine season.</div></div><div><h3>Conclusions</h3><div>Vaccine access, education, and peer-reviewed information remain drivers of HCP vaccine uptake. Strategies should address occupational disparities and emphasize transmission risks.</div></div>","PeriodicalId":38066,"journal":{"name":"Preventive Medicine Reports","volume":"58 ","pages":"Article 103233"},"PeriodicalIF":2.4,"publicationDate":"2025-09-08","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145049273","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"A telehealth lifestyle change program for rural Wisconsin, U.S. families at risk for diabetes: feasibility pilot results","authors":"Susan J. Andreae ,&nbsp;Emily Hickey ,&nbsp;Carol Van Hulle ,&nbsp;Angela J. Flickinger","doi":"10.1016/j.pmedr.2025.103240","DOIUrl":"10.1016/j.pmedr.2025.103240","url":null,"abstract":"<div><h3>Objectives</h3><div>Family-based programs acknowledge that health behaviors are shaped by familial and environmental contexts. Since family history increases the risk for type-2 diabetes (T2DM), focusing on families may reduce modifiable risks in adults while promoting healthy habits in children. We conducted a 12-week telehealth pilot study with rural Wisconsin families to improve family health climate and reduce diabetes risk.</div></div><div><h3>Methods</h3><div>While caregiver-child dyads with a family history of T2DM were enrolled spring 2023 and 2024, all family members were included in the intervention. Primary outcomes related to feasibility were assessed through semi-structured interviews. Secondary outcomes, collected pre- and post-intervention, included objective measures of physical activity and self-reported global health, physical activity, and social support.</div></div><div><h3>Results</h3><div>Seventeen dyads (<em>N</em> = 34) enrolled, fifteen completed the study with 86 % adherence. Interviews indicated the program was feasible and well-received, with participants offering suggestions for improvement. At post-intervention caregivers increased weekly physical activity by 42.4 min (<em>p</em> = .01), and children's mean daily step counts increased by 1226.3 steps (<em>p</em> = .08).</div></div><div><h3>Conclusions</h3><div>This telehealth, family-focused lifestyle change program was feasible, with promising results in physical activity and social support. Including caregivers and children may positively influence adult health while fostering healthier habits in youth at elevated risk for T2DM.</div></div>","PeriodicalId":38066,"journal":{"name":"Preventive Medicine Reports","volume":"58 ","pages":"Article 103240"},"PeriodicalIF":2.4,"publicationDate":"2025-09-07","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145049276","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"The association of Gastro-esophageal reflux disease and self-reported myocardial-infarction among World Trade Center disaster exposed persons","authors":"Robert Brackbill,&nbsp;Ayda Ahmadi,&nbsp;Howard Alper,&nbsp;Jiehui Li,&nbsp;Shengchao Yu","doi":"10.1016/j.pmedr.2025.103232","DOIUrl":"10.1016/j.pmedr.2025.103232","url":null,"abstract":"<div><h3>Objective</h3><div>Gastroesophageal reflux disease (GERD) is the third most prevalent condition among responders and survivors who are monitored and treated in World Trade Center Health Program. Given the evidence of a potential association between GERD and myocardial-infarction, this study used observational data from the World Trade Center Health Registry (WTCHR) located in New York City Department of Health and Mental Hygiene, to evaluate the risk of myocardial-infarction from GERD.</div></div><div><h3>Methods</h3><div>The study used five waves of survey data from 2003 to 2020 of the WTCHR to estimate the hazard ratio for persons who reported both GERD and gastroesophageal symptoms (GERS) compared to those with no-GERD in relation to a self-reported myocardial infarction. GERD cases and no-GERD controls were matched by age and sex; pairs of cases and controls were assigned index GERD diagnosis year for start of observation.</div></div><div><h3>Results</h3><div>With a final sample of 13,234, proportional hazard analysis yielded an unadjusted HR = 2.0 (95 % CI, 1.67, 2.49) and HR = 1.7 (95 % CI, 1.32, 2.19) after adjusting for putative confounders.</div></div><div><h3>Conclusions</h3><div>A nearly two-fold risk of myocardial-infarction among those with 9/11 disaster related GERD is concerning given the high prevalence of GERD among persons who were exposed to the 9/11 disaster.</div></div>","PeriodicalId":38066,"journal":{"name":"Preventive Medicine Reports","volume":"58 ","pages":"Article 103232"},"PeriodicalIF":2.4,"publicationDate":"2025-09-06","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145027019","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Socioeconomic differences in prevalence and patterns of non-communicable disease multimorbidity and its impact on depression in rural Southwest China","authors":"Lan Liu ,&nbsp;Guo-hui Li ,&nbsp;Xia Wu ,&nbsp;Bo Lv ,&nbsp;Allison Rabkin Golden ,&nbsp;Ling-Li Dong ,&nbsp;Le Cai","doi":"10.1016/j.pmedr.2025.103235","DOIUrl":"10.1016/j.pmedr.2025.103235","url":null,"abstract":"<div><h3>Objective</h3><div>This study aimed to uncover socioeconomic variations in the prevalence and patterns of noncommunicable disease (NCD) multimorbidity including seven common chronic conditions, and to investigate its association with depression symptoms.</div></div><div><h3>Methods</h3><div>A cross-sectional survey was conducted including 7509 adults aged ≥35 years in rural Yunnan Province, China from 2023 to 2024. Association rule mining was used to identify the NCD multimorbidity patterns of seven common chronic conditions. Multivariable logistic regression analysis was employed to examine the relationship between NCD multimorbidity and depression symptoms.</div></div><div><h3>Results</h3><div>The prevalence of NCD multimorbidity was 18.8 %. NCD multimorbidity was more prevalent among participants with lower education, lower annual household income, and better access to medical care (<em>P</em> &lt; 0.05). NCD multimorbidity and their patterns of chronic obstructive pulmonary disease + asthma, diabetes + coronary heart disease, hypertension + stroke, and hypertension + coronary heart disease + diabetes were associated with a greater risk of depression symptoms (<em>P</em> &lt; 0.05).</div></div><div><h3>Conclusions</h3><div>There are socioeconomic disparities in prevalence and patterns of NCD multimorbidity across rural southwest China. NCD multimorbidity was positively associated with depressive symptoms. Future measures to prevention NCD multimorbidity should be strengthened and targeted at lower socioeconomic populations, with greater focus on managing depression in NCD multimorbid patients.</div></div>","PeriodicalId":38066,"journal":{"name":"Preventive Medicine Reports","volume":"58 ","pages":"Article 103235"},"PeriodicalIF":2.4,"publicationDate":"2025-09-04","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145010005","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}