{"title":"Associations between adverse childhood experiences and insomnia: The moderating role of social capital in a three-year longitudinal study from the Japan Gerontological Evaluation Study","authors":"Nao Tomono , Masamichi Hanazato , Katsunori Kondo , Kazushige Ide , Atsushi Nakagomi","doi":"10.1016/j.pmedr.2025.103319","DOIUrl":"10.1016/j.pmedr.2025.103319","url":null,"abstract":"<div><h3>Objective</h3><div>Adverse childhood experiences (ACEs) are linked to sleep disturbances later in life. Social capital may promote better sleep among older adults, but its moderating role remains unclear. We examined whether social capital modifies the ACE–insomnia association.</div></div><div><h3>Methods</h3><div>Longitudinal data from the Japan Gerontological Evaluation Study (2013–2016, Japan) included 8890 adults aged 65 years and older. Insomnia in 2016 was assessed with the Athens Insomnia Scale. ACEs were measured retrospectively in 2016, and social capital in 2013 across civic participation, social cohesion and reciprocity. Poisson regression estimated relative risks (RR) of insomnia. Effect-measure modification (EMM) was evaluated on multiplicative and additive scales.</div></div><div><h3>Results</h3><div>More ACEs were associated with a higher probability of insomnia (per +1 ACE: RR = 1.19; 95 % CI = 1.15, 1.23). Higher civic participation, social cohesion, and reciprocity were inversely associated with insomnia (RRs = 0.87–0.94). EMM was limited: civic participation showed a small interaction in the amplifying direction (multiplicative RR = 1.04; <em>p</em> = 0.03), whereas social cohesion and reciprocity showed no interaction.</div></div><div><h3>Conclusions</h3><div>Social capital showed limited modification of the ACE–insomnia association. Social cohesion remained independently protective, while civic participation slightly amplified the association. Fostering cohesive, supportive communities may promote sleep health in later life, including among those with ACE histories.</div></div>","PeriodicalId":38066,"journal":{"name":"Preventive Medicine Reports","volume":"60 ","pages":"Article 103319"},"PeriodicalIF":2.4,"publicationDate":"2025-12-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145615122","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"First consumption of alcohol and drugs: When does it start, in which occasions and what can we do to prevent it?","authors":"Ivona Vrkić Boban , Marijan Saraga","doi":"10.1016/j.pmedr.2025.103296","DOIUrl":"10.1016/j.pmedr.2025.103296","url":null,"abstract":"<div><h3>Objectives</h3><div>The prevalence of alcohol use among adolescents in Croatia is high. The aim of this study was to determine the age and circumstances of first alcohol and drug consumption among adolescents.</div></div><div><h3>Methods</h3><div>An online questionnaire survey was conducted among final-year high school students in Split-Dalmatia County, Croatia, between June 6 and December 28, 2020. Statistical analyses were performed using chi-square test, with a <em>P</em>-value <0.05 considered as statistically significant.</div></div><div><h3>Results</h3><div>Among 1030 respondents, 92.33 % reported having consumed alcohol at least once, with 33 % initiating use at ≤14 years of age. The youngest age of the first alcohol consumption was three years, and the median age was 15 years (IQR = 14.00–16.00). Most participants first tasted beer (34.38 %), primarily out of curiosity (63.93 %), at their own home (28.29 %) friend's homes (27.44 %), or in nightclubs or café bars (27.23 %). A total of 24.27 % reported having tried drugs, most commonly marijuana (92.40 %), usually with friends (88.80 %). The youngest age of the first drug use was six years, and the median age was 16 years (IQR = 15.00–17.00).</div></div><div><h3>Conclusions</h3><div>First use of alcohol and drugs occurs at an early age, often in familiar environments. Enhanced educational and preventive measures beginning in early childhood are essential to prevent engagement in risky behaviors among children.</div></div>","PeriodicalId":38066,"journal":{"name":"Preventive Medicine Reports","volume":"60 ","pages":"Article 103296"},"PeriodicalIF":2.4,"publicationDate":"2025-12-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145468242","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Utilization of youth-friendly sexual and reproductive health care services among secondary school students in southern Ethiopia","authors":"Yonas Abebe , Daniel Yehualashet","doi":"10.1016/j.pmedr.2025.103287","DOIUrl":"10.1016/j.pmedr.2025.103287","url":null,"abstract":"<div><h3>Objective</h3><div>This study assesses the utilization of Youth-Friendly Sexual and Reproductive Health Care Services and associated factors among secondary school students in Southern Ethiopia, 2024.</div></div><div><h3>Methods</h3><div>An institution-based cross-sectional study was conducted among 365 students in Dilla Town from August to December 2024. Participants were selected from all six secondary schools using a stratified random sampling method. Binary logistic regression was employed to identify factors associated with youth-friendly sexual and reproductive health services. Statistical significance was defined as <em>p</em> < 0.05. Data were analyzed using SPSS version 26.</div></div><div><h3>Results</h3><div>The prevalence of youth friendly sexual and reproductive health care utilization was 38.6 % (95 % CI: 33.6, 43.8). Factors significantly associated with utilization included urban residency (AOR = 1.96, 95 % CI: 1.03, 3.71), acceptance of service confidentiality (AOR = 5.95, 95 % CI: 3.04, 11.65), absence of stigma (AOR = 3.99, 95 % CI: 2.04,7.78), proximity of service centers (AOR = 2.58, 95 % CI: 1.27, 5.22), social media use (AOR = 3.09, 95 % CI: 1.13, 8.50), and open family communication on SRH (AOR = 5.99, 95 % CI: 2.16, 16.64).</div></div><div><h3>Conclusions</h3><div>Utilization of youth-friendly sexual and reproductive health services was low. Strengthening confidentiality, reducing stigma, and promoting family communication are critical for improving uptake and supporting informed health choices<strong>.</strong></div></div>","PeriodicalId":38066,"journal":{"name":"Preventive Medicine Reports","volume":"60 ","pages":"Article 103287"},"PeriodicalIF":2.4,"publicationDate":"2025-12-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145468244","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Comment on “Association between the dietary index for gut microbiota and osteoporosis among middle-aged and older adults in the United States”","authors":"Xiaoling Xu","doi":"10.1016/j.pmedr.2025.103303","DOIUrl":"10.1016/j.pmedr.2025.103303","url":null,"abstract":"<div><div>The recent NHANES-based study by Zhan et al. (2025) investigated the association between the dietary index for gut microbiota (DI-GM) and osteoporosis, reporting that higher DI-GM scores were linked to lower osteoporosis prevalence. While the study provides valuable exploratory evidence, several limitations may affect its clinical and public health implications. First, residual confounding may remain, as weight-bearing exercise, vitamin D status, calcium/phosphate metabolism, sex hormones, and family history were not incorporated. Second, generalizability is constrained: the sample was predominantly White and higher-income, dietary cultures shape gut microbiota composition, and osteopenia—a key prevention target—was excluded. Third, the absence of subgroup analyses may obscure heterogeneity across high-risk groups, especially postmenopausal women, in whom pathophysiological drivers and intervention effects differ. Finally, the outcome definition (femoral neck DXA T-score ≤ −2.5) does not fully align with clinical decision-making, which primarily relies on fragility fractures and FRAX-estimated 10-year probabilities. Future research should integrate broader metabolic and behavioral determinants, validate DI-GM across diverse populations and dietary contexts, include osteopenic individuals, and align outcomes with fracture risk to enhance clinical and public health utility.</div></div>","PeriodicalId":38066,"journal":{"name":"Preventive Medicine Reports","volume":"60 ","pages":"Article 103303"},"PeriodicalIF":2.4,"publicationDate":"2025-12-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145736045","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Max R. O'Reilly , Thomas J. Stopka , Ric Bayly , Olivia Lewis , Shikhar Shrestha , Jack Cordes , Alexander Y. Walley , Sumeeta Srinivasan
{"title":"Public transit and methadone – Spatial analyses of opioid treatment program access in Greater Boston, 2020–2022","authors":"Max R. O'Reilly , Thomas J. Stopka , Ric Bayly , Olivia Lewis , Shikhar Shrestha , Jack Cordes , Alexander Y. Walley , Sumeeta Srinivasan","doi":"10.1016/j.pmedr.2025.103317","DOIUrl":"10.1016/j.pmedr.2025.103317","url":null,"abstract":"<div><h3>Objective</h3><div>Methadone, an FDA-approved medication, can effectively treat opioid use disorder (OUD). However, long travel times to opioid treatment programs (OTPs) commonly present barriers to initiating and continuing methadone treatment. We utilized geographic information systems to identify areas with unmet OTP access needs via public transportation and walking in Boston, Massachusetts.</div></div><div><h3>Methods</h3><div>We created public transit-time and walk-time catchment areas around OTPs. We assessed spatial overlap between the catchment areas and locations of opioid-related overdose decedent residences from 2020 to 2022 in Boston, and inequities in OTP access by decedent race/ethnicity using logistic regression.</div></div><div><h3>Results</h3><div>In Greater Boston, 50.1% of fatal opioid-related overdose decedent residences were within 30 min of an OTP via public transit at the time of death. In Boston, 80.4% of fatal opioid-related overdose decedent residences were within 30-min transit times of an OTP. In the early morning, access to OTPs on public transit is limited. Differences in OTP access based on decedent race/ethnicity were inconsistent.</div></div><div><h3>Conclusion</h3><div>Many areas in Greater Boston have unmet OTP access needs on public transit. Our results can inform decision-making to improve OTP access in Boston, such as increased early-morning transit service, expanding access to methadone beyond existing OTPs, or broadening non-emergent medical transit.</div></div>","PeriodicalId":38066,"journal":{"name":"Preventive Medicine Reports","volume":"60 ","pages":"Article 103317"},"PeriodicalIF":2.4,"publicationDate":"2025-12-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145615066","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Improving preventive screening efficiency: A population-based model of age-specific mammographic density for breast Cancer detection in Saudi Arabia","authors":"Sahal Alotaibi","doi":"10.1016/j.pmedr.2025.103321","DOIUrl":"10.1016/j.pmedr.2025.103321","url":null,"abstract":"<div><h3>Objective</h3><div>Current age-based breast cancer screening protocols may not be optimally effective as they overlook mammographic density as a key risk factor. This study developed a personalized risk stratification model by analyzing age-specific mammographic density patterns to improve screening accuracy and reduce false-positive rates.</div></div><div><h3>Methods</h3><div>A cross-sectional analysis was performed on mammographic data from 2584 women aged 32–90 years from October 2023–December 2024. Breast Imaging Reporting and Data System (BI-RADS) density classifications were analyzed using polynomial regression and changepoint analysis to identify critical age thresholds. Four age-density clusters were derived, and a gradient boosting model was developed to evaluate predictive accuracy.</div></div><div><h3>Results</h3><div>The analysis identified three significant age thresholds (42.3, 51.7, and 65.2 years) where mammographic density patterns shifted. Four risk clusters were established, and the model achieved high predictive accuracy (Area Under the Curve [AUC] = 0.83). Simulations projected that personalized screening protocols could increase cancer detection by 14.7 % and reduce false positives by 9.7 % compared to traditional age-only approaches.</div></div><div><h3>Conclusions</h3><div>Age-specific mammographic density screening offers a data-driven method to advance breast cancer prevention. It provides a framework for developing more effective screening policies that can decrease morbidity, supporting a shift toward risk-based screening as standard care.</div></div>","PeriodicalId":38066,"journal":{"name":"Preventive Medicine Reports","volume":"60 ","pages":"Article 103321"},"PeriodicalIF":2.4,"publicationDate":"2025-12-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145615147","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Jesper Mulder , Anne K. Smit , Mirte Boelens , Jessica C. Kiefte-de Jong
{"title":"A 50-week walking intervention for type 2 diabetes mellitus: A pilot study to improve fitness, BMI, and quality of life outcomes","authors":"Jesper Mulder , Anne K. Smit , Mirte Boelens , Jessica C. Kiefte-de Jong","doi":"10.1016/j.pmedr.2025.103299","DOIUrl":"10.1016/j.pmedr.2025.103299","url":null,"abstract":"<div><h3>Objective</h3><div>This study investigated whether a multicomponent 50-week walking intervention, including guidance from lifestyle professionals, improved physical fitness, body mass index (BMI), and quality of life (QoL).</div></div><div><h3>Methods</h3><div>Forty-five Dutch individuals with or at high risk of type 2 diabetes mellitus (T2DM) participated in this pilot study between April 2023 and March 2024. Total intervention duration was 50 weeks, of which 30 weeks with guidance and 20 weeks without guidance. Physical fitness (6MWT), BMI, and QoL were assessed at week 0 (T0), 30 (T1), and 50 (T2). The experience of participants and professionals (<em>n</em> = 17) was also inventoried.</div></div><div><h3>Results</h3><div>Linear mixed models on all 45 participants indicated no significant changes over time. Participants with complete data (<em>n</em> = 12) indicated a significant change in EQ-VAS (β = 4.792, CI = 1.439, 8.145) over time, while 6MWT, BMI, and EQ-index did not change.</div></div><div><h3>Conclusion</h3><div>This pilot study elicited positive responses by participants and professionals. However, adherence to the intervention could not be assessed based on the questionnaire responses. A multicomponent walking intervention with lifestyle coaching could be used to optimize lifestyle interventions in T2DM, although the current study showed that individual differences, motivation, and adherence to changes should be considered.</div></div>","PeriodicalId":38066,"journal":{"name":"Preventive Medicine Reports","volume":"60 ","pages":"Article 103299"},"PeriodicalIF":2.4,"publicationDate":"2025-12-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145468261","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Yonghwan Moon , Min Seung Choi , Soo Jin Kim , Hyekyung Woo
{"title":"The association of workload during healthcare service disruption with the mental health of prehospital emergency medical service providers in Korea","authors":"Yonghwan Moon , Min Seung Choi , Soo Jin Kim , Hyekyung Woo","doi":"10.1016/j.pmedr.2025.103311","DOIUrl":"10.1016/j.pmedr.2025.103311","url":null,"abstract":"<div><h3>Objective</h3><div>In 2024, a large-scale healthcare service disruption occurred in Korea due to ongoing conflict between the government and medical professionals over the proposed expansion of medical school admissions. This study examined how workload burdens experienced by prehospital emergency medical service (EMS) providers during the disruption affected their mental health.</div></div><div><h3>Methods</h3><div>We analyzed associations between workload factors, including delayed return to base, urgent administrative tasks, and missed meals, and mental-health outcomes, including depressive symptoms, burnout, and sleep problems, in a sample of 851 prehospital EMS providers.</div></div><div><h3>Results</h3><div>The results show that EMS providers who experienced delayed return to base were more likely to report depressive symptoms (OR = 2.22, 95 % CI: 1.52, 3.23), those involved in urgent administrative tasks reported higher levels of burnout (OR = 1.83, 95 % CI: 1.28, 2.61), and those who frequently missed meals were more likely to experience sleep problems (OR = 1.89, 95 % CI: 1.33, 2.67).</div></div><div><h3>Conclusions</h3><div>These findings imply that different types of workload burdens during healthcare service disruptions are significantly associated with mental health outcomes among prehospital EMS providers, highlighting the need for institutional strategies to protect their psychological well-being during similar crisis situations.</div></div>","PeriodicalId":38066,"journal":{"name":"Preventive Medicine Reports","volume":"60 ","pages":"Article 103311"},"PeriodicalIF":2.4,"publicationDate":"2025-12-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145520289","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Implementation of the whole school, whole community, whole child model in Makkah schools, Saudi Arabia: association with students' body mass index and academic achievement","authors":"Mohamed O. Nour","doi":"10.1016/j.pmedr.2025.103308","DOIUrl":"10.1016/j.pmedr.2025.103308","url":null,"abstract":"<div><h3>Objective</h3><div>To assess the implementation of the Whole School, Whole Community, Whole Child (WSCC) model in public elementary schools in Makkah, Saudi Arabia, and examine its association with students<strong>'</strong> body mass index (BMI) and academic achievement.</div></div><div><h3>Methods</h3><div>A cross-sectional study was conducted in 2022 across 20 elementary schools in Makkah using multistage cluster sampling. Participants included 385 students and 32 school staff from health-promoting schools (HPSs) and non-HPSs. Implementation of four WSCC domains; community involvement, family engagement, physical environment, and counseling services, was assessed using validated self-administered questionnaires. Academic scores, BMI, and sociodemographic data were collected. Data analysis utilized descriptive statistics, bivariate tests, Spearman correlations, and multivariable linear regression.</div></div><div><h3>Results</h3><div>Students in HPSs reported higher WSCC implementation and academic achievement than those in non-HPSs (median score: 687 vs. 665, <em>p</em> = 0.009). In multivariable models, WSCC implementation remained an independent predictor of academic achievement after adjustment (B = 1.63, <strong>95 %</strong> CI: 0.90, 2.35), whereas its association with BMI was not significant (B = 0.36, <strong>95 %</strong> CI: <strong>−</strong>0.32, 1.04). A dual burden of underweight and overweight was observed.</div></div><div><h3>Conclusions</h3><div>Strengthening WSCC implementation, especially mental health support, family and community engagement, and equitable policy adoption, may enhance students<strong>'</strong> learning and well-being.</div></div>","PeriodicalId":38066,"journal":{"name":"Preventive Medicine Reports","volume":"60 ","pages":"Article 103308"},"PeriodicalIF":2.4,"publicationDate":"2025-12-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145520871","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Morgan Johnson , Amy Ratcliff , Linda Chia , Carol Callaway-Lane , Mary S. Dietrich , Deonni P. Stolldorf , Todd Hulgan , Christianne L. Roumie
{"title":"Sexual health assessments, testing, and pre-exposure prophylaxis referrals among veterans with a sexually transmitted infection","authors":"Morgan Johnson , Amy Ratcliff , Linda Chia , Carol Callaway-Lane , Mary S. Dietrich , Deonni P. Stolldorf , Todd Hulgan , Christianne L. Roumie","doi":"10.1016/j.pmedr.2025.103307","DOIUrl":"10.1016/j.pmedr.2025.103307","url":null,"abstract":"<div><h3>Objective</h3><div>Describe sexual history completion among U.S. Veterans with a sexually transmitted infection (STI) and its association with number of ordered STI laboratory tests and offer of human immunodeficiency virus (HIV) pre-exposure prophylaxis (PrEP).</div></div><div><h3>Methods</h3><div>We assembled a retrospective cohort of Veterans with a STI seen at five sites in the southern United States and excluded those with diagnosis of HIV. We conducted a systematic chart review of sexual history using Centers for Disease Control and Prevention's five ‘Ps.’ The outcome was STI testing and PrEP offer. Charts were reviewed between December 2021 and May 2022.</div></div><div><h3>Results</h3><div>No sexual history was documented in 43 % of the 278 encounters with differences across sites (<em>p</em> < 0.001). Missing documentation occurred for: partners (67 %); practices (93 %); protection (75 %); pregnancies (24 %, 14/58 females) and prior STIs (78 %). No association was observed between sexual history and complete STI testing (<em>p</em> = 0.42) but a positive association between sexual history components and individual STI tests, except HIV, was present (<em>p</em> ≤ 0.001). PrEP was offered to 1.4 % (4/278) of Veterans.</div></div><div><h3>Conclusions</h3><div>Low sexual history documentation were associated with less STI tests ordered. PrEP referrals were low. Improvements in sexual history taking and PrEP offerings are essential.</div></div>","PeriodicalId":38066,"journal":{"name":"Preventive Medicine Reports","volume":"60 ","pages":"Article 103307"},"PeriodicalIF":2.4,"publicationDate":"2025-12-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145520874","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}