{"title":"Eating behaviors among chinese older adults: A qualitative study using the capability, opportunity, motivation, and behavior model","authors":"Qian Wang, Qian Li","doi":"10.1016/j.pmedr.2025.103156","DOIUrl":"10.1016/j.pmedr.2025.103156","url":null,"abstract":"<div><h3>Objective</h3><div>This study explored the mechanisms underlying eating behaviors among Chinese older adults using the COM-B model, which conceptualizes behavior through Capability, Opportunity, and Motivation components.</div></div><div><h3>Methods</h3><div>A qualitative descriptive design was adopted. Semi-structured interviews were conducted with 20 community-dwelling older adults in Zhenjiang, Jiangsu Province, China, from October to December 2024. Thematic analysis was employed to analyze the data.</div></div><div><h3>Results</h3><div>Four major themes were identified: Restrictive Eating, Emotional Eating, Nutritional Literacy, and External Eating. Dietary patterns were influenced by physical health conditions, emotional states, family dynamics, and digital barriers to food information access.</div></div><div><h3>Conclusions</h3><div>Eating behaviors among older adults are shaped by complex and interconnected factors across individual, social, and environmental domains. Interventions promoting healthy aging should integrate strategies to enhance capability, optimize opportunity, and strengthen motivation.</div></div>","PeriodicalId":38066,"journal":{"name":"Preventive Medicine Reports","volume":"56 ","pages":"Article 103156"},"PeriodicalIF":2.4,"publicationDate":"2025-06-29","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144535090","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Katelin M. Alfaro Hudak , Lindsey Breunig-Rodriguez , Renda J. Nelson , Elizabeth F. Racine
{"title":"A Fresh Start to a Healthier You! program improves fruit and vegetable consumption and risk of food insecurity: Findings from Texas","authors":"Katelin M. Alfaro Hudak , Lindsey Breunig-Rodriguez , Renda J. Nelson , Elizabeth F. Racine","doi":"10.1016/j.pmedr.2025.103158","DOIUrl":"10.1016/j.pmedr.2025.103158","url":null,"abstract":"<div><h3>Objective</h3><div>The goal of Supplemental Nutrition Assistance Program Education (SNAP-Ed) is to increase the likelihood that individuals with lower incomes who are eligible for SNAP benefits will choose healthy foods within a limited budget and be physically active. This study aimed to evaluate how participation in a Texas SNAP-Ed program <em>A Fresh Start to a Healthier You!</em> (<em>Fresh Start</em>) was associated with participants' fruit and vegetable consumption, use of food resource management strategies, and risk of food insecurity.</div></div><div><h3>Methods</h3><div>The study used survey data collected February 2021–September 2023 from counties across Texas. This single group pre/post evaluation used generalized linear models to assess changes in outcomes from baseline to program completion. Models adjusted for age, sex, race/ethnicity, and educational attainment.</div></div><div><h3>Results</h3><div>Participants who completed <em>Fresh Start</em> were 18–20 percentage points more likely to utilize food resource management strategies (average marginal effect [AME]: 18.2–20.0, <em>p</em> < 0.0001). The average change in being at risk of food insecurity decreased 3 percentage points (AME: 3.2, <em>p</em> = 0.012) following completion of <em>Fresh Start.</em> Measures of F&V intake significantly increased (AME: 6.7–36.3, <em>p</em> < 0.001), and the average number of days participants engaged in physical activity each week increased by 0.7 (AME: 0.7, <em>p</em> < 0.0001). Participation in <em>Fresh Start</em> was associated with improved food security, greater utilization of food resource management strategies, and increased fruit and vegetable consumption and physical activity.</div></div><div><h3>Conclusion</h3><div>This study supports the use of SNAP-Ed and other nutrition education programs as one avenue to improve food security and diet behavior in households with lower incomes.</div></div>","PeriodicalId":38066,"journal":{"name":"Preventive Medicine Reports","volume":"56 ","pages":"Article 103158"},"PeriodicalIF":2.4,"publicationDate":"2025-06-29","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144523309","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Changes in public awareness of racial, economic, and educational health disparities between 2007 and 2023 among Wisconsin adults","authors":"Stephanie A. Robert, Amy Yinan Liu","doi":"10.1016/j.pmedr.2025.103159","DOIUrl":"10.1016/j.pmedr.2025.103159","url":null,"abstract":"<div><h3>Objective</h3><div>To investigate 15-year changes in public awareness of racial, economic, and educational health disparities between 2007 and 2023.</div></div><div><h3>Methods</h3><div>Surveys of Wisconsin, U.S. adults in 2007 and 2023 were compared. Respondents in both surveys were randomized into panels to examine opinions about specific health disparities—Black/White, economic, or educational health disparities. Bivariate and logistic regression analyses examine how demographic factors differentiate awareness of disparities and changes in awareness over 15 years.</div></div><div><h3>Results</h3><div>Overall awareness of Black/White and educational health disparities rose between 2007 and 2023; awareness of economic health disparities remained at a similar high level both years. Despite overall increases in awareness of health disparities, some demographic differences in awareness persisted between years by age, gender, race, education, and party identification. There are particularly large differences between Republicans and Democrats in awareness of each type of health disparity. The increase in awareness of Black/White health disparities grew much faster over 15 years for Democrats than Republicans.</div></div><div><h3>Conclusions</h3><div>The overall increase in awareness of health disparities is encouraging if improvement in public awareness helps drive initiatives to address the disparities. However, the large and even growing political divide on health disparity awareness is concerning and our results support calls for deep attention to how to bridge huge partisan divides in understanding and addressing health disparities to improve health and health equity in the U.S.</div></div>","PeriodicalId":38066,"journal":{"name":"Preventive Medicine Reports","volume":"56 ","pages":"Article 103159"},"PeriodicalIF":2.4,"publicationDate":"2025-06-29","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144535091","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Dana Mowls Carroll , Andy Tan , Mackenzie Differding , Olivia A. Wackowski , Dana Rubenstein , Dorothy K. Hatsukami , Devon Noonan , F. Joseph McClernon
{"title":"Beliefs regarding nicotine replacement therapy among rural residing people who smoke: a step towards promoting uptake","authors":"Dana Mowls Carroll , Andy Tan , Mackenzie Differding , Olivia A. Wackowski , Dana Rubenstein , Dorothy K. Hatsukami , Devon Noonan , F. Joseph McClernon","doi":"10.1016/j.pmedr.2025.103155","DOIUrl":"10.1016/j.pmedr.2025.103155","url":null,"abstract":"<div><h3>Objective</h3><div>Rural areas in the United States (U.S.) have a higher smoking prevalence than urban areas. This disparity is influenced by lower odds of quitting smoking in rural versus urban areas, and lower use of evidence-based treatments, including nicotine replacement therapy (NRT). To inform strategies for promoting NRT, this qualitative study elicited and ranked NRT beliefs among rural people who smoke cigarettes.</div></div><div><h3>Methods</h3><div>In 2023, we conducted an online, semi-qualitative, elicitation survey with US rural residing adults (ages 21+) who smoke (<em>n</em> = 52), using open-ended questions to probe about: perceived advantages/disadvantages of using NRT to quit smoking and facilitators/barriers towards using NRT. Responses were coded based on belief themes and the frequencies of these themes were tabulated.</div></div><div><h3>Results</h3><div>Leading perceived advantages of NRT for a quit attempt included help with cravings (42 %), making quitting easier (23 %) and easing withdrawal (17 %), while perceived disadvantages were concerns about becoming addicted to another product (29 %), high cost (23 %), side effects (19 %), and being ineffective (13–17 %). Leading perceived barriers to NRT use referred to high cost (52 %), negative taste (19 %), not enough nicotine (13 %), and lack of access (11 %), while leading perceived facilitators to use were free or lower cost (54 %) and better access/availability (13 %) and flavors/taste (13 %).</div></div><div><h3>Conclusions</h3><div>Boosting NRT use among rural communities could be achieved by (1) adopting approaches to enhance the affordability and accessibility of NRT, (2) rectifying NRT misperceptions, and (3) offering guidance on the proper use of NRT and managing side effects.</div></div>","PeriodicalId":38066,"journal":{"name":"Preventive Medicine Reports","volume":"56 ","pages":"Article 103155"},"PeriodicalIF":2.4,"publicationDate":"2025-06-28","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144514225","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Takuya Yamada , Kumi Sugimoto , Hanae Nagata , Yoshiharu Fukuda , Koryu Sato , Naoki Kondo
{"title":"Heterogeneous effects on body mass index in the “checkup championship”: A behavioral science-based health promotion program by health interest level","authors":"Takuya Yamada , Kumi Sugimoto , Hanae Nagata , Yoshiharu Fukuda , Koryu Sato , Naoki Kondo","doi":"10.1016/j.pmedr.2025.103153","DOIUrl":"10.1016/j.pmedr.2025.103153","url":null,"abstract":"<div><h3>Objective</h3><div>Behavioral science principles, including approaches such as gamification, commitment strategies, and nudges, are widely used in health promotion programs to prevent non-communicable diseases. These approaches are expected to influence behavior change regardless of health interest; however, their effectiveness remains unclear. This study evaluated the impact of a behavioral science-based health promotion program on body mass index (BMI) reduction across different levels of health interest.</div></div><div><h3>Methods</h3><div>This study evaluated the “Checkup Championship,” a program that applies various behavioral science strategies to improve health checkup results for employees at Hakuhodo DY Group in Japan. Participants in the program in 2020 were compared with non-participants. Health interest was classified as low, middle, or high based on a single-question assessment. A linear regression model analyzed BMI changes between 2019 and 2020, using the inverse probability weighting of propensity scores to adjust for background differences between groups.</div></div><div><h3>Results</h3><div>A total of 410 participants and 390 non-participants were included in the study. BMI reduction was greater among participants than non-participants (−0.36 kg/m<sup>2</sup> vs. −0.12 kg/m<sup>2</sup>). A significant BMI reduction was observed in the middle (average treatment effect [ATE]: −0.30 kg/m<sup>2</sup>, 95 % confidence interval [CI]: −0.55, −0.06) and low health interest groups (ATE: −0.34 kg/m<sup>2</sup>, 95 % CI: −0.61, −0.08); however, no clear BMI reduction was seen in the high health interest group.</div></div><div><h3>Conclusions</h3><div>The “Checkup Championship” demonstrated effectiveness, particularly among individuals with a lower health interest. Health programs incorporating diverse behavioral science strategies may help reduce health disparities.</div></div>","PeriodicalId":38066,"journal":{"name":"Preventive Medicine Reports","volume":"56 ","pages":"Article 103153"},"PeriodicalIF":2.4,"publicationDate":"2025-06-28","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144556749","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Factors predicting renal impairment associated with Tenofovir Disoproxil fumarate: Focus on patients with HIV and pre-existing metabolic abnormalities under the Thai National Health Security Scheme","authors":"Duangjai Duangrithi , Kwandaw Silathong","doi":"10.1016/j.pmedr.2025.103154","DOIUrl":"10.1016/j.pmedr.2025.103154","url":null,"abstract":"<div><h3>Objective</h3><div>The incidence of nephrotoxicity is reported as 20 % among Thai patients with HIV receiving tenofovir disoproxil fumarate (TDF). It can occur as early as 24 weeks after initiating TDF therapy. Metabolic abnormalities are the major comorbidities in patients with HIV receiving antiretrovirals. However, close monitoring for renal function and metabolic abnormalities is not possible under Thai National Health Security Scheme for either HIV or AIDS patients due to the significant budget constraints. This study aims to investigate the predictive factors of TDF associated with renal impairment in patients with HIV and pre-existing metabolic abnormalities.</div></div><div><h3>Methods</h3><div>This longitudinal study was conducted at a university hospital in Bangkok, Thailand from January 2015 to December 2018. All participants were followed until the first occurrence of an estimated glomerular filtration rate (eGFR) ≤ 90 mL/min/1.73 m<sup>2</sup>.</div></div><div><h3>Results</h3><div>Among 315 patients with pre-existing metabolic abnormalities, elevated low-density lipoprotein was the most common (47.3 %) while TDF/emtricitabine/efavirenz was the most common (75.2 %) regimen of highly active antiretroviral therapy. In addition, the body mass index (BMI) < 18.5 kg/m<sup>2</sup> (odds ratio [OR] = 9.20, 95 % confidence interval [CI]: 1.11, 76.50) and baseline eGFR (OR = 0.92, 95 % CI: 0.89, 0.94) were predictive factors of renal impairment.</div></div><div><h3>Conclusions</h3><div>For patients with HIV and pre-existing metabolic abnormalities in resource limited settings, maintaining a normal BMI and adjusting antiretroviral treatment dose according to renal function are recommended, especially in those with abnormal baseline eGFR.</div></div>","PeriodicalId":38066,"journal":{"name":"Preventive Medicine Reports","volume":"56 ","pages":"Article 103154"},"PeriodicalIF":2.4,"publicationDate":"2025-06-27","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144535089","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Camila Carla Souza do Prado , Maria Cláudia Bernardes Spexoto , Wanderson Roberto da Silva , Deise Bresan , Bruna Menegassi
{"title":"Sociocultural pressures and appearance ideal internalization: Their impact on body dissatisfaction in Brazilian adults","authors":"Camila Carla Souza do Prado , Maria Cláudia Bernardes Spexoto , Wanderson Roberto da Silva , Deise Bresan , Bruna Menegassi","doi":"10.1016/j.pmedr.2025.103149","DOIUrl":"10.1016/j.pmedr.2025.103149","url":null,"abstract":"<div><h3>Objective</h3><div>To analyze the relationship between internalization of appearance ideals, sociocultural pressures, and body dissatisfaction among Brazilian adults.</div></div><div><h3>Methods</h3><div>A cross-sectional study was conducted in Mato Grosso do Sul, Brazil, between January and December 2023. Using convenience sampling, data were collected from 290 adults (18–64 years old; median age = 24.0, IQR25 = 21.0, and IQR75 = 34.0; 69.3 % female) through an online self-report questionnaire. The dependent variables included socioeconomic, demographic, and anthropometric data. Sociocultural pressures and the internalization of appearance ideals were measured using the SATAQ-4, with body dissatisfaction as the independent variable. Statistical analyses involved non-parametric tests (Kolmogorov-Smirnov, Mann-Whitney U, Kruskal-Wallis, Dunn's post hoc tests) and Spearman's correlation, with a significance level set at <em>p</em> < .05.</div></div><div><h3>Results</h3><div>Body dissatisfaction was 84.5 % prevalent. Dissatisfaction related to excess weight was associated with pressure from family (<em>p</em> < .001), friends (<em>p</em> = .001), the media (p < .001), and internalization of the thin ideal (p < .001). The median ideal athletic/muscular body was significantly higher in males than in females (<em>p</em> = .015), while median media pressure was higher in females compared to males (<em>p</em> = .001).</div></div><div><h3>Conclusions</h3><div>The study highlights the role of sociocultural pressures and appearance ideals in body dissatisfaction, supporting the Tripartite Influence Model.</div></div>","PeriodicalId":38066,"journal":{"name":"Preventive Medicine Reports","volume":"56 ","pages":"Article 103149"},"PeriodicalIF":2.4,"publicationDate":"2025-06-27","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144502616","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Association between the non-high-density lipoprotein cholesterol to high-density lipoprotein cholesterol ratio and Sarcopenic obesity in U.S. adults: a cross-sectional study","authors":"Jiao Liu , Fujue Ji , Jong-Hee Kim","doi":"10.1016/j.pmedr.2025.103151","DOIUrl":"10.1016/j.pmedr.2025.103151","url":null,"abstract":"<div><h3>Objective</h3><div>This study examines the relationship between the ratio of non-high-density lipoprotein cholesterol to high-density lipoprotein cholesterol (NHHR) and sarcopenic obesity in U.S. adults, utilizing data from the National Health and Nutrition Examination Survey (NHANES).</div></div><div><h3>Methods</h3><div>We analysed data from NHANES collected between 2011 and 2018. Multivariable regression models assessed the NHHR-sarcopenic obesity relationship, and limited cubic spline analysis investigated potential non-linearity. We employed likelihood ratio tests to evaluate model fit and performed subgroup analyses to verify the consistency of our findings.</div></div><div><h3>Results</h3><div>The analysis included 8601 participants with an average age of 39.94 ± 11.45 years. In the fully adjusted model, each unit increase in NHHR was associated with a 76 % higher likelihood of sarcopenic obesity (odds ratio [OR]: 1.76, 95 % confidence interval [CI]: 1.18–2.63). The relationship between NHHR and sarcopenic obesity was non-linear, with a significant breakpoint at 3.36. Below this threshold, each unit increase in NHHR significantly increased the risk of sarcopenic obesity (OR: 1.53, 95 % CI: 1.32–1.78), while above this threshold, NHHR had no significant effect on sarcopenic obesity prevalence.</div></div><div><h3>Conclusions</h3><div>These results indicate a positive and non-linear association between NHHR and sarcopenic obesity, suggesting that NHHR, as a simple and widely available lipid marker, may assist in the early identification of individuals at risk of sarcopenic obesity. Further large-scale longitudinal studies are needed to validate its predictive value across broader age groups and to clarify its potential utility in personalized risk assessment and clinical screening.</div></div>","PeriodicalId":38066,"journal":{"name":"Preventive Medicine Reports","volume":"56 ","pages":"Article 103151"},"PeriodicalIF":2.4,"publicationDate":"2025-06-26","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144490614","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Nathaniel J. Maxey , José A. Pagán , Brennan Rhodes-Bratton , Anjali Phalke , Marina Mautner Wizentier , Kimberly A. Kaphingst , Melody S. Goodman , Jemar R. Bather
{"title":"A quasi-experimental study of New York City's sodium warning regulation and hypertension prevalence, 2005–2020","authors":"Nathaniel J. Maxey , José A. Pagán , Brennan Rhodes-Bratton , Anjali Phalke , Marina Mautner Wizentier , Kimberly A. Kaphingst , Melody S. Goodman , Jemar R. Bather","doi":"10.1016/j.pmedr.2025.103152","DOIUrl":"10.1016/j.pmedr.2025.103152","url":null,"abstract":"<div><h3>Objective</h3><div>To quantify temporal trends in age-adjusted hypertension prevalence in New York City before and after implementation of a menu labeling regulation requiring sodium warning icons at chain restaurants.</div></div><div><h3>Methods</h3><div>Using data from the New York City Community Health Survey, segmented regression models assessed: (1) the average annual percent change (AAPC) of age-adjusted hypertension prevalence during the pre-regulation period (2005–2015), (2) the annual percent change (APC) from 2015 to 2016 (regulation onset association), (3) the AAPC of age-adjusted hypertension prevalence during the regulation period (2016–2020), and (4) the percentage-point difference between the AAPCs of the pre-regulation and regulation periods.</div></div><div><h3>Results</h3><div>We found a statistically significant average annual percent increase in the age-adjusted hypertension prevalence among the Hispanic population during the pre-regulation period (2005–2015 AAPC: 1.3 %, 95 % CI: 0.3 % to 2.3 %). The regulation's onset was significantly associated with a 4.2 % (95 % CI: 0.4 % to 8.0 %) increase in the age-adjusted hypertension prevalence among females from 2015 to 2016. During the regulation era, we observed statistically significant average annual percent decreases in age-adjusted hypertension prevalence among Black (2016–2020 AAPC: −1.9 %; 95 % CI: −2.5 % to −1.3 %) and female (2016–2020 AAPC: −3.5 %; 95 % CI: −5.0 % to −2.1 %) subgroups.</div></div><div><h3>Conclusions</h3><div>Findings suggest a potential positive impact of the sodium warning regulation on hypertension prevalence. The decreasing trends in hypertension prevalence among female and Black populations suggest that sodium reduction policies may have differential impacts across subgroups. These empirical insights underscore the importance of sustained sodium reduction policies.</div></div>","PeriodicalId":38066,"journal":{"name":"Preventive Medicine Reports","volume":"56 ","pages":"Article 103152"},"PeriodicalIF":2.4,"publicationDate":"2025-06-26","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144490621","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Post-licensure safety of respiratory syncytial virus vaccines, Vaccine Adverse Event Reporting System, United States, May 2023–December 2024","authors":"Junchao Li , Zhiyuan Zhang , Meixiang Wang","doi":"10.1016/j.pmedr.2025.103150","DOIUrl":"10.1016/j.pmedr.2025.103150","url":null,"abstract":"<div><h3>Objective</h3><div>Respiratory syncytial virus (RSV) vaccines, including Arexvy and Abrysvo, received approval in May 2023. The study aims to review the post-licensure safety of RSV vaccines by investigating adverse events using the Vaccine Adverse Event Reporting System (VAERS).</div></div><div><h3>Methods</h3><div>We included VAERS reports of RSV vaccination in United States between May 3, 2023, and December 27, 2024. The study performed descriptive analysis, clinical review of death and pre-specified conditions, and data mining using empirical Bayesian methods.</div></div><div><h3>Results</h3><div>VEARS received 6790 U.S. reports following administration of RSV vaccines. The median age of vaccine recipients was 71 years, with females comprising 64.9 %. Guillain-Barré syndrome (GBS) was the most common adverse event among serious reports. Injection site reaction was the most common non-serious report. 53 reports mention death, and the most frequent cause was sudden cardiac death. We identified 19 reports of anaphylaxis, 14 reports of cellulitis within 7 days of onset, and 81 reports of GBS. 63.2 % of vaccinees during pregnancy did not report adverse event, and the most common adverse event, was preterm delivery. Data mining displayed that various preferred terms were not identical based on vaccine and age stratification adverse event.</div></div><div><h3>Conclusions</h3><div>The study reviewed the post-licensure safety of RSV vaccines and suggested that a significant proportion of adverse events were not serious, which aligned with previous studies. Preterm delivery and GBS following the administration of RSV vaccines require continuous monitoring. Additionally, inappropriate administration of Arexvy in pregnant individuals should be paid attention to.</div></div>","PeriodicalId":38066,"journal":{"name":"Preventive Medicine Reports","volume":"56 ","pages":"Article 103150"},"PeriodicalIF":2.4,"publicationDate":"2025-06-26","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144501713","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}