Preventive Medicine Reports最新文献

{"title":"Knowledge, attitude, and practice towards postmenopausal osteoporosis among postmenopausal women: A cross-sectional study","authors":"Feng Xiong ,&nbsp;Aoqi Zang ,&nbsp;Zhe Xu ,&nbsp;Qingyi Cao ,&nbsp;Ziquan Shen ,&nbsp;Feng Qian ,&nbsp;Hui Xu","doi":"10.1016/j.pmedr.2025.103234","DOIUrl":"10.1016/j.pmedr.2025.103234","url":null,"abstract":"<div><h3>Objective</h3><div>Postmenopausal osteoporosis, affecting 33 % of women over 60 in China, increases fracture risks and significantly impacts quality of life. This condition leads to physical disability and psychological distress, underscoring the need for targeted interventions. This study aimed to assess the knowledge, attitude, and practice (KAP) of postmenopausal women concerning postmenopausal osteoporosis and explore associated factors.</div></div><div><h3>Methods</h3><div>A cross-sectional study was conducted from June 29 to September 8, 2024, at the First People's Hospital of Bengbu City using a self-administered questionnaire to assess KAP, and data were analyzed using descriptive statistics and nonparametric tests.</div></div><div><h3>Results</h3><div>A total of 459 valid participants in the study, of whom 166 (36.17 %) were diagnosed with postmenopausal osteoporosis. Among those diagnosed with osteoporosis, 65 (39.16 %) received systematic treatment. The mean scores for knowledge, attitude, and practice were 10.03 ± 5.47 (range: 0–28), 28.03 ± 3.07 (range: 8–40), and 21.87 ± 5.10 (range: 7–35), respectively.</div></div><div><h3>Conclusion</h3><div>While postmenopausal women demonstrated insufficient knowledge and inadequate practices, targeted educational efforts may help improve osteoporosis-related behaviors and outcomes. These findings highlight the need for targeted educational interventions to improve osteoporosis-related knowledge and encourage proactive behaviors in managing the disease.</div></div>","PeriodicalId":38066,"journal":{"name":"Preventive Medicine Reports","volume":"58 ","pages":"Article 103234"},"PeriodicalIF":2.4,"publicationDate":"2025-09-08","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145049274","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Factors associated with healthcare personnel uptake of updated COVID-19 vaccine doses in the United States","authors":"Eric Kontowicz ,&nbsp;Kari K. Harland ,&nbsp;Amy Stubbs ,&nbsp;David Beiser ,&nbsp;Ian Plumb ,&nbsp;Anusha Krishnadasan ,&nbsp;David A. Talan ,&nbsp;Nicholas M. Mohr","doi":"10.1016/j.pmedr.2025.103233","DOIUrl":"10.1016/j.pmedr.2025.103233","url":null,"abstract":"<div><h3>Objective</h3><div>Evaluate factors associated with United States (US) healthcare personnel (HCP) uptake of an updated COVID-19 vaccine.</div></div><div><h3>Methods</h3><div>We analyzed data from 887 US HCP enrolled between September 25, 2023, and April 17, 2024, in a multisite case-control COVID-19 vaccine effectiveness study. Sociodemographic and attitudinal data were collected via standardized surveys, and vaccination status was verified using source documentation.</div></div><div><h3>Results</h3><div>Overall, 188 (21.2 %) HCP received the updated vaccine. HCP aged 50–64 years (adjusted odds ratio [aOR] 2.02, 95 % CI: 1.11–3.67) versus ages 18–29, and HCP with undergraduate (aOR 3.75, 95 % CI: 1.97–7.12) or graduate degrees (aOR 7.73, 95 % CI: 4.10–14.55) versus high school/some college had higher odds of vaccination. Nurses and nurse assistants had lower odds (aOR 0.48, 95 % CI: 0.30–0.76) versus other job roles. Vaccinated HCP were more likely than unvaccinated HCP to cite concerns about personal infection (89.9 % vs. 44.6 %), infecting family/friends (96.3 % vs. 56.0 %), vaccine availability (63.3 % vs. 18.9 %), and peer-reviewed literature (56.4 % vs. 28.3 %) as important influences. These factors remained consistent with findings from a prior vaccine season.</div></div><div><h3>Conclusions</h3><div>Vaccine access, education, and peer-reviewed information remain drivers of HCP vaccine uptake. Strategies should address occupational disparities and emphasize transmission risks.</div></div>","PeriodicalId":38066,"journal":{"name":"Preventive Medicine Reports","volume":"58 ","pages":"Article 103233"},"PeriodicalIF":2.4,"publicationDate":"2025-09-08","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145049273","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"A telehealth lifestyle change program for rural Wisconsin, U.S. families at risk for diabetes: feasibility pilot results","authors":"Susan J. Andreae ,&nbsp;Emily Hickey ,&nbsp;Carol Van Hulle ,&nbsp;Angela J. Flickinger","doi":"10.1016/j.pmedr.2025.103240","DOIUrl":"10.1016/j.pmedr.2025.103240","url":null,"abstract":"<div><h3>Objectives</h3><div>Family-based programs acknowledge that health behaviors are shaped by familial and environmental contexts. Since family history increases the risk for type-2 diabetes (T2DM), focusing on families may reduce modifiable risks in adults while promoting healthy habits in children. We conducted a 12-week telehealth pilot study with rural Wisconsin families to improve family health climate and reduce diabetes risk.</div></div><div><h3>Methods</h3><div>While caregiver-child dyads with a family history of T2DM were enrolled spring 2023 and 2024, all family members were included in the intervention. Primary outcomes related to feasibility were assessed through semi-structured interviews. Secondary outcomes, collected pre- and post-intervention, included objective measures of physical activity and self-reported global health, physical activity, and social support.</div></div><div><h3>Results</h3><div>Seventeen dyads (<em>N</em> = 34) enrolled, fifteen completed the study with 86 % adherence. Interviews indicated the program was feasible and well-received, with participants offering suggestions for improvement. At post-intervention caregivers increased weekly physical activity by 42.4 min (<em>p</em> = .01), and children's mean daily step counts increased by 1226.3 steps (<em>p</em> = .08).</div></div><div><h3>Conclusions</h3><div>This telehealth, family-focused lifestyle change program was feasible, with promising results in physical activity and social support. Including caregivers and children may positively influence adult health while fostering healthier habits in youth at elevated risk for T2DM.</div></div>","PeriodicalId":38066,"journal":{"name":"Preventive Medicine Reports","volume":"58 ","pages":"Article 103240"},"PeriodicalIF":2.4,"publicationDate":"2025-09-07","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145049276","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"The association of Gastro-esophageal reflux disease and self-reported myocardial-infarction among World Trade Center disaster exposed persons","authors":"Robert Brackbill,&nbsp;Ayda Ahmadi,&nbsp;Howard Alper,&nbsp;Jiehui Li,&nbsp;Shengchao Yu","doi":"10.1016/j.pmedr.2025.103232","DOIUrl":"10.1016/j.pmedr.2025.103232","url":null,"abstract":"<div><h3>Objective</h3><div>Gastroesophageal reflux disease (GERD) is the third most prevalent condition among responders and survivors who are monitored and treated in World Trade Center Health Program. Given the evidence of a potential association between GERD and myocardial-infarction, this study used observational data from the World Trade Center Health Registry (WTCHR) located in New York City Department of Health and Mental Hygiene, to evaluate the risk of myocardial-infarction from GERD.</div></div><div><h3>Methods</h3><div>The study used five waves of survey data from 2003 to 2020 of the WTCHR to estimate the hazard ratio for persons who reported both GERD and gastroesophageal symptoms (GERS) compared to those with no-GERD in relation to a self-reported myocardial infarction. GERD cases and no-GERD controls were matched by age and sex; pairs of cases and controls were assigned index GERD diagnosis year for start of observation.</div></div><div><h3>Results</h3><div>With a final sample of 13,234, proportional hazard analysis yielded an unadjusted HR = 2.0 (95 % CI, 1.67, 2.49) and HR = 1.7 (95 % CI, 1.32, 2.19) after adjusting for putative confounders.</div></div><div><h3>Conclusions</h3><div>A nearly two-fold risk of myocardial-infarction among those with 9/11 disaster related GERD is concerning given the high prevalence of GERD among persons who were exposed to the 9/11 disaster.</div></div>","PeriodicalId":38066,"journal":{"name":"Preventive Medicine Reports","volume":"58 ","pages":"Article 103232"},"PeriodicalIF":2.4,"publicationDate":"2025-09-06","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145027019","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Socioeconomic differences in prevalence and patterns of non-communicable disease multimorbidity and its impact on depression in rural Southwest China","authors":"Lan Liu ,&nbsp;Guo-hui Li ,&nbsp;Xia Wu ,&nbsp;Bo Lv ,&nbsp;Allison Rabkin Golden ,&nbsp;Ling-Li Dong ,&nbsp;Le Cai","doi":"10.1016/j.pmedr.2025.103235","DOIUrl":"10.1016/j.pmedr.2025.103235","url":null,"abstract":"<div><h3>Objective</h3><div>This study aimed to uncover socioeconomic variations in the prevalence and patterns of noncommunicable disease (NCD) multimorbidity including seven common chronic conditions, and to investigate its association with depression symptoms.</div></div><div><h3>Methods</h3><div>A cross-sectional survey was conducted including 7509 adults aged ≥35 years in rural Yunnan Province, China from 2023 to 2024. Association rule mining was used to identify the NCD multimorbidity patterns of seven common chronic conditions. Multivariable logistic regression analysis was employed to examine the relationship between NCD multimorbidity and depression symptoms.</div></div><div><h3>Results</h3><div>The prevalence of NCD multimorbidity was 18.8 %. NCD multimorbidity was more prevalent among participants with lower education, lower annual household income, and better access to medical care (<em>P</em> &lt; 0.05). NCD multimorbidity and their patterns of chronic obstructive pulmonary disease + asthma, diabetes + coronary heart disease, hypertension + stroke, and hypertension + coronary heart disease + diabetes were associated with a greater risk of depression symptoms (<em>P</em> &lt; 0.05).</div></div><div><h3>Conclusions</h3><div>There are socioeconomic disparities in prevalence and patterns of NCD multimorbidity across rural southwest China. NCD multimorbidity was positively associated with depressive symptoms. Future measures to prevention NCD multimorbidity should be strengthened and targeted at lower socioeconomic populations, with greater focus on managing depression in NCD multimorbid patients.</div></div>","PeriodicalId":38066,"journal":{"name":"Preventive Medicine Reports","volume":"58 ","pages":"Article 103235"},"PeriodicalIF":2.4,"publicationDate":"2025-09-04","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145010005","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Fetal loss in women exposed to cigarette smoke in-utero","authors":"Talita Honorato-Rzeszewicz ,&nbsp;Annemieke Hoek ,&nbsp;Maaike L. Haadsma ,&nbsp;Henk Groen","doi":"10.1016/j.pmedr.2025.103228","DOIUrl":"10.1016/j.pmedr.2025.103228","url":null,"abstract":"<div><h3>Objective</h3><div>Animal studies have shown meiotic errors in follicles after exposure to cigarette smoke in-utero. Epidemiological studies investigating effects of in-utero smoke exposure on fetal loss in humans show inconclusive results and did not control for extraneous smoke exposure. We aimed to investigate the association between cigarette smoke exposure in-utero and risk of fetal loss, independent of active or second-hand smoking.</div></div><div><h3>Methods</h3><div>We used data from the Avon Longitudinal Study of Parents and Children (ALSPAC) cohort (<em>n</em> = 15,445, April 1991–December 1992, Bristol, England). From obstetric history data and questionnaires completed by the participants we assessed previous fetal loss and whether the participant's mother smoked when pregnant with the participant, smoking habits and second-hand smoking. Fetal loss was defined as miscarriage up to 28 weeks of gestation or stillbirth. We performed logistic regression adjusting for confounding and stratifying for smoke exposure.</div></div><div><h3>Results</h3><div>In 7033 women in-utero smoke exposure and fetal loss status were known; 2012 were exposed to smoke in-utero; 687 of them (34.1 %) ever had a fetal loss. Ever smokers with exposure in-utero (<em>n</em> = 1182) had higher odds of ever having a fetal loss than ever smokers unexposed in-utero (<em>n</em> = 2354, adjusted OR: 1.26; 95 % CI: 1.08, 1.47, <em>p</em>-value &lt; 0.01 for interaction between ever smoking and in-utero exposure). Evaluation of less common combinations of in-utero and extraneous smoke exposure was hampered by small numbers.</div></div><div><h3>Conclusions</h3><div>In-utero smoke exposure is associated with increased odds of fetal loss when occurring in combination with active smoking of the participants, compounding the odds of fetal loss.</div></div>","PeriodicalId":38066,"journal":{"name":"Preventive Medicine Reports","volume":"58 ","pages":"Article 103228"},"PeriodicalIF":2.4,"publicationDate":"2025-09-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144933065","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Self-perceived food literacy is positively associated with diet quality among Dutch individuals with type 2 diabetes","authors":"Iris van Damme,&nbsp;Eva R. van Veldhuisen,&nbsp;Johanna M. Geleijnse,&nbsp;Renate M. Winkels","doi":"10.1016/j.pmedr.2025.103229","DOIUrl":"10.1016/j.pmedr.2025.103229","url":null,"abstract":"<div><h3>Objective</h3><div>This cross-sectional study was conducted to investigate associations between food literacy and diet quality among individuals with type 2 diabetes.</div></div><div><h3>Method</h3><div>In the Netherlands in 2022/2023, 166 individuals with type 2 diabetes (66.8 ± 10.3 years, BMI 28.2 ± 4.3 kg/m²) completed questionnaires. Self-perceived food literacy (SPFL) was assessed using the 29-item SPFL-scale (score 1–5, higher scores indicating higher food literacy). Diet quality was assessed with a brief frequency questionnaire (FFQ; score 0–160, higher scores indicating higher diet quality). Associations between food literacy and diet quality were evaluated with linear models.</div></div><div><h3>Results</h3><div>Mean diet quality score was 107 ± 16 and mean food literacy score was 3.7 ± 0.4. Linear regression showed that 1-point higher food literacy scores were associated with 14-point higher diet quality scores (β adjusted 14.0; 95 % CI: 8.4 to 19.6). Individuals with above-median food literacy scores had diet quality scores that were 12.5 points higher (95 % CI: 7.7 to 17.3) than individuals with below-median scores. Food preparation skills, healthy budgeting, social and conscious eating, resilience and resistance, and healthy snack styles, were associated with better diet quality.</div></div><div><h3>Conclusion</h3><div>Associations between several food literacy domains and diet quality in people with type 2 diabetes indicate the importance of promoting food literacy in this group.</div></div>","PeriodicalId":38066,"journal":{"name":"Preventive Medicine Reports","volume":"58 ","pages":"Article 103229"},"PeriodicalIF":2.4,"publicationDate":"2025-08-30","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144989053","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Global situation of oral health coverage toward universal health coverage: A scoping review","authors":"Mohsen Sharif Zadeh Ardakani ,&nbsp;Mohsen Bayati","doi":"10.1016/j.pmedr.2025.103227","DOIUrl":"10.1016/j.pmedr.2025.103227","url":null,"abstract":"<div><h3>Objective</h3><div>This study investigates the status of Universal Health Coverage in oral/dental services from the perspectives of population, service, and cost coverage, as well as other aspects of financing, using a scoping review.</div></div><div><h3>Method</h3><div>A scoping review of published articles from 2000 to 2024 was conducted, utilizing scientific databases including PubMed, Scopus, Web of Science, Embase, and ProQuest, along with other sources such as grey literature and Google Scholar.</div></div><div><h3>Result</h3><div>The initial search identified 58,778 articles, with 28 articles included in the final analysis after screening and full-text review. The included countries were Australia, Bulgaria, Canada, China, Finland, France, Germany, Greece, India, Iran, Ireland, Italy, Japan, Netherlands, Poland, Romania, Spain, Sudan, Sweden, Thailand, Turkey, United Kingdom, Ukraine, and the United States. The condition of oral health coverage was reported by factors such as dental health expenditure, coverage type, service and cost coverage, coverage of age/specific groups, and cost sharing.</div></div><div><h3>Conclusion</h3><div>Dental services are mainly provided by the private sector, do not have adequate public coverage and are mainly financed by out-of-pocket payments. However, Dental health expenditure and coverage vary significantly across countries, influenced by diverse healthcare systems, economic conditions, and public health priorities. Countries like Sweden and the United Kingdom demonstrate strong public funding commitments, providing comprehensive coverage for preventive and basic services. In contrast, countries like Australia and the United States rely more on private insurance, leading to higher out-of-pocket costs for individuals. Addressing high out-of-pocket payments and ensuring equitable access to oral health care remain key challenges.</div></div>","PeriodicalId":38066,"journal":{"name":"Preventive Medicine Reports","volume":"58 ","pages":"Article 103227"},"PeriodicalIF":2.4,"publicationDate":"2025-08-30","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144926263","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"A United States study of self-collected urine vs clinician-collected cervical sample for HPV and cervical intraepithelial neoplasia grade two or worse detection: Cross-sectional agreement and diagnostic accuracy study","authors":"Alisa P. Young ,&nbsp;Marie Claire O'Dwyer ,&nbsp;Roger Smith ,&nbsp;Dongru Chen ,&nbsp;Ananda Sen ,&nbsp;Heather M. Walline ,&nbsp;Diane M. Harper ,&nbsp;MISSH1 study group","doi":"10.1016/j.pmedr.2025.103222","DOIUrl":"10.1016/j.pmedr.2025.103222","url":null,"abstract":"<div><h3>Objectives</h3><div>Urine can provide a non-invasive screening method for high-risk human papillomavirus (hrHPV) infections. We aimed to compare detection rates of hrHPV and cervical intraepithelial neoplasia grade two or worse (CIN2+) using first-void urine (FVU) and clinician-collected cervical samples. We assessed whether the time of day of FVU collection impacts hrHPV detection.</div></div><div><h3>Methods</h3><div>We recruited 188 participants, 30–65 years, before their colposcopy or routine screening from September 2020 through February 2022. Each collected FVU twice on the same day: at home and in the clinic before their appointments. We used prevalence-adjusted bias-adjusted kappa (PABAK) scores to compare hrHPV type-specific agreement, followed by McNemar's Exact test. We assessed both absolute and relative sensitivity and specificity to evaluate the accuracy of the collection techniques in predicting CIN2+ by hrHPV type.</div></div><div><h3>Results</h3><div>95 hrHPV infections were detected in 70/188 (37.2 %) women. The PABAK agreement for hrHPV16 detection between FVU and the speculum was 0.95 (95 % CI: 0.91, 1.0). The agreement for hrHPV detection was almost perfect between home or clinic urine collection and the speculum specimen. The accuracy of CIN2+ detection measured by the sensitivity ratio of the clinic first-void specimen compared to the speculum specimen for hrHPV16 was 1.00 (0.62, 6.20). Most specificity ratios for all other hrHPV types were anchored at 1.0 with narrow confidence intervals. The time of day for FVU gave similar “any hrHPV” detection rates (27.5 % vs 32 %, <em>p</em> &gt; 0.05).</div></div><div><h3>Conclusion</h3><div>FVU hrHPV testing offers a potential cervical cancer screening alternative for women who cannot tolerate other collections.</div></div>","PeriodicalId":38066,"journal":{"name":"Preventive Medicine Reports","volume":"58 ","pages":"Article 103222"},"PeriodicalIF":2.4,"publicationDate":"2025-08-30","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144926172","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Effects of physical exercise on negative emotions in adolescents: Sequential mediation through psychological benefits and social self-efficacy","authors":"Xin Yang ,&nbsp;Liuheng Lu","doi":"10.1016/j.pmedr.2025.103231","DOIUrl":"10.1016/j.pmedr.2025.103231","url":null,"abstract":"<div><h3>Objective</h3><div>Negative emotions during adolescence constitute a significant public health challenge requiring theoretically-grounded intervention approaches. This investigation examined sequential mediation mechanisms whereby physical exercise influences adolescent negative emotions through psychological benefits and social self-efficacy pathways, integrating neurobiological and social-cognitive theoretical frameworks.</div></div><div><h3>Methods</h3><div>Cross-sectional analysis of 1471 Chinese adolescents (Mean age = 13.16 years) from Guangxi, China, with data collected in September 2024, employed structural equation modeling with bias-corrected bootstrapping to test hypothesized sequential mediation pathways. Physical exercise, psychological benefits, social self-efficacy, and negative emotions were assessed using validated instruments.</div></div><div><h3>Results</h3><div>The sequential mediation model showed acceptable fit (χ²/df = 3.09, comparative fit index = 0.97, root mean square error of approximation = 0.04, standardized root mean square residual = 0.04). Physical exercise was directly associated with lower negative emotions and indirectly through psychological benefits. A sequential pathway from exercise → psychological benefits → social self-efficacy → negative emotions was also observed. The model explained 56 % of the variance in negative emotions.</div></div><div><h3>Conclusions</h3><div>Findings demonstrate that exercise influences adolescent negative emotions through both direct neurobiological mechanisms (31.7 % of total effect) and sequential psychological adaptation processes (68.3 % of total effect). Programs that enhance perceived psychological gains from exercise and build social efficacy may deliver meaningful emotional benefits.</div></div>","PeriodicalId":38066,"journal":{"name":"Preventive Medicine Reports","volume":"58 ","pages":"Article 103231"},"PeriodicalIF":2.4,"publicationDate":"2025-08-29","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144919765","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}