Revista de Senologia y Patologia Mamaria最新文献_第4页

Correlación entre la carga tumoral total de los ganglios linfáticos analizada mediante One Step Nucleic Acid Amplification (OSNA) y la decisión de realizar una linfadenectomía axilar en el cáncer de mama temprano 采用一步核酸扩增法（OSNA）检测的淋巴结总肿瘤负担与早期乳腺癌中进行腋下淋巴结切除术的决定之间的相关性

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Revista de Senologia y Patologia Mamaria Pub Date : 2025-02-05 DOI: 10.1016/j.senol.2025.100667

Paula Chamocho Lloro , María Dolores Rodríguez Garnica , Beatriz Sánchez Jimenez , Sergio Rodriguez Lobalzo , Angel Calvo Tudela , Alejandro J. Rohde Calleja , Francisco Rivas Ruiz , José C. Maañón di Leo

{"title":"Correlación entre la carga tumoral total de los ganglios linfáticos analizada mediante One Step Nucleic Acid Amplification (OSNA) y la decisión de realizar una linfadenectomía axilar en el cáncer de mama temprano","authors":"Paula Chamocho Lloro , María Dolores Rodríguez Garnica , Beatriz Sánchez Jimenez , Sergio Rodriguez Lobalzo , Angel Calvo Tudela , Alejandro J. Rohde Calleja , Francisco Rivas Ruiz , José C. Maañón di Leo","doi":"10.1016/j.senol.2025.100667","DOIUrl":"10.1016/j.senol.2025.100667","url":null,"abstract":"<div><h3>Introduction</h3><div>The aim of this study was to determine the correlation between total lymph load (TLL) analyzed by one step nucleic acid amplification (OSNA) and the results obtained in our clinical practice, and whether TTL is a useful tool for selecting patients who should undergo axillary lymph node dissection.</div></div><div><h3>Material and methods</h3><div>The study has a retrospective cohort design, conducted at the Hospital Costa de Sol on 92 patients with (GC+) analyzed by OSNA, between 2012 and 2017.</div></div><div><h3>Results</h3><div>Disease-free survival was analyzed classifying patients into micro-metastatic, macro-metastatic with less than 25,000 copies of mRNA-CK19/ul, and macro-metastatic with more than 25,000 copies of mRNA-CK19/ul, with no statistical significance found between groups (log-rank test 0.266266).</div></div><div><h3>Discussion</h3><div>The recommendation of axillary lymph node dissection (ALND) in conservatively operated patients with clinically (or radiologically) negative axilla and high tumor load as determined by OSNA is not related to local disease control.</div></div>","PeriodicalId":38058,"journal":{"name":"Revista de Senologia y Patologia Mamaria","volume":"38 2","pages":"Article 100667"},"PeriodicalIF":0.3,"publicationDate":"2025-02-05","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143341654","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

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Del Ars Magna a la inteligencia artificial generativa 从大Ars Magna到生成人工智能

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Revista de Senologia y Patologia Mamaria Pub Date : 2025-02-03 DOI: 10.1016/j.senol.2024.100663

Rafael Berlanga Llavori

引用次数: 0

¿Es posible realizar la biopsia selectiva de ganglio centinela (BSGC) en una paciente con mastectomía preservadora de piel y pezón? Descripción de un caso 是否有可能对进行皮肤和乳头保守性乳房切除术的患者进行选择性前哨神经节活检（BSGC）？案例描述

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Revista de Senologia y Patologia Mamaria Pub Date : 2025-01-30 DOI: 10.1016/j.senol.2025.100665

Miriam Alcaide Lucena , Carlos José Rodríguez González , Rafael Nieto Serrano , Jesús García Rubio , Benito Mirón Pozo

{"title":"¿Es posible realizar la biopsia selectiva de ganglio centinela (BSGC) en una paciente con mastectomía preservadora de piel y pezón? Descripción de un caso","authors":"Miriam Alcaide Lucena , Carlos José Rodríguez González , Rafael Nieto Serrano , Jesús García Rubio , Benito Mirón Pozo","doi":"10.1016/j.senol.2025.100665","DOIUrl":"10.1016/j.senol.2025.100665","url":null,"abstract":"<div><div>BRCA mutation carriers have an increased risk of breast cancer. Among the risk-reducing measures is prophylactic bilateral mastectomy. In less than 1%  of BRCA patients undergoing this surgery, previously undetected breast cancer is found. Routine sentinel lymph node biopsy has not shown benefit because few patients have occult cancer, and it is a technique that also involves morbidity. If a carcinoma is found in the specimen, axillary staging should be done in a second procedure, which has traditionally been performed with lymphadenectomy due to the absence of breast tissue and the belief that sentinel lymph node biopsy (SLNB) is not feasible. We present the case of a patient diagnosed with an infiltrating tumor in the left mastectomy specimen, and successful SLNB performed in a second procedure. Four nodes were sent for intraoperative analysis with negative results. Axillary lymphadenectomy was avoided, achieving proper axillary staging. It is technically feasible to perform SLNB after a skin- and nipple-sparing mastectomy, avoiding systematic axillary lymphadenectomy for staging in these patients, thus avoiding the morbidity associated with this technique.</div></div>","PeriodicalId":38058,"journal":{"name":"Revista de Senologia y Patologia Mamaria","volume":"38 2","pages":"Article 100665"},"PeriodicalIF":0.3,"publicationDate":"2025-01-30","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143141960","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

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Cáncer de mama bilateral sincrónico en el varón. Descripción de un caso y revisión de la bibliografía 男性双侧同步乳腺癌。案例说明和参考书目审查

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Revista de Senologia y Patologia Mamaria Pub Date : 2025-01-23 DOI: 10.1016/j.senol.2024.100664

Noelia Lete Aguirre, Jorge Martínez Medel, Antonio Tomás Güemes Sánchez

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Can we use HER2DX to modulate treatment intensity in HER2 positive early breast cancer? 我们可以使用HER2DX来调节HER2阳性早期乳腺癌的治疗强度吗？

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Revista de Senologia y Patologia Mamaria Pub Date : 2025-01-21 DOI: 10.1016/j.senol.2024.100659

Beatriz Alonso De Castro , Cristina Reboredo Rendo , Fernanda Mosele , Eva Pérez López , Lourdes Calvo Martínez , Silvia Antolín Novoa

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Accelerating cancer diagnostics: A novel AI pipeline for efficient histopathological image analysis 加速癌症诊断：高效组织病理图像分析的新型人工智能管道

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Revista de Senologia y Patologia Mamaria Pub Date : 2025-01-15 DOI: 10.1016/j.senol.2024.100662

David Anglada-Rotger , Sonia Rabanaque-Rodríguez , Laura Sáez-Parés , Jordi Temprana-Salvador

{"title":"Accelerating cancer diagnostics: A novel AI pipeline for efficient histopathological image analysis","authors":"David Anglada-Rotger , Sonia Rabanaque-Rodríguez , Laura Sáez-Parés , Jordi Temprana-Salvador","doi":"10.1016/j.senol.2024.100662","DOIUrl":"10.1016/j.senol.2024.100662","url":null,"abstract":"<div><div>The surge in digital pathology and the vast amount of data from whole slide images (WSIs) have made it essential to develop tools that can efficiently analyze and support cancer diagnosis. An innovative artificial intelligence-based pipeline has been developed to tackle this challenge, significantly speeding up and enhancing the accuracy of breast cancer diagnosis. Created within the DigiPatICS project, in partnership with 8 hospitals across Catalonia, Spain, this pipeline begins by identifying tissue areas in WSIs and breaking them down into smaller, manageable tiles. Using smart image processing techniques, it filters out tiles that do not contain relevant information and focuses on the essential ones. Advanced deep learning algorithms then work to identify and classify different types of cells within the tissue. Proven effective on key breast cancer markers like HER2, Ki67, ER, and PR, the system precomputes the results overnight, allowing pathologists to simply load the pre-analyzed data for the areas of interest of the WSI that they select during their workday. Each WSI is analyzed in more or less 1110 s, providing reliable results that are ready when needed. Now, an integral part of routine workflows, this approach is revolutionizing how breast cancer slides are processed, enhancing diagnostic capabilities, and reshaping digital pathology.</div></div>","PeriodicalId":38058,"journal":{"name":"Revista de Senologia y Patologia Mamaria","volume":"38 3","pages":"Article 100662"},"PeriodicalIF":0.3,"publicationDate":"2025-01-15","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143132586","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Descripcion de un caso de carcinoma papilar encapsulado apocrino de mama: un dilema diagnóstico 隐窝乳腺乳头状瘤的诊断困境

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Revista de Senologia y Patologia Mamaria Pub Date : 2025-01-03 DOI: 10.1016/j.senol.2024.100653

José Richard Tenazoa-Villalobos , Edgar Fermín Yan-Quiroz , Gladys Llerena-Cobián

{"title":"Descripcion de un caso de carcinoma papilar encapsulado apocrino de mama: un dilema diagnóstico","authors":"José Richard Tenazoa-Villalobos , Edgar Fermín Yan-Quiroz , Gladys Llerena-Cobián","doi":"10.1016/j.senol.2024.100653","DOIUrl":"10.1016/j.senol.2024.100653","url":null,"abstract":"<div><div>Encapsulated papillary carcinoma of the breast with apocrine differentiation is an extremely rare neoplasm that possesses both an encapsulated papillary configuration as well as epithelial cells that differentiated apocrine. It is not included as such in the fifth edition of the World Health Organization (WHO) classification of tumors because there are no research studies on the subject. These neoplasms have cells that are distinguished by having granular cytoplasm, large nuclei with prominent nucleoli, through immunohistochemistry these tumors are negative for estrogen, progesterone and HER2 receptors, but despite the absence of these markers and the nuclear atypia described, they have an overall survival that exceeds 5 years compared even to the other types of triple-negative breast neoplasm. We present the case of an 85-year-old woman who presented a right breast tumor that was classified as apocrine encapsulated papillary carcinoma, underwent right total mastectomy surgery and allowed the control of the disease, thus achieving a favorable outcome.</div></div>","PeriodicalId":38058,"journal":{"name":"Revista de Senologia y Patologia Mamaria","volume":"38 2","pages":"Article 100653"},"PeriodicalIF":0.3,"publicationDate":"2025-01-03","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143141961","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

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Los colgajos de perforantes en la cirugía del cáncer de mama 乳腺癌手术中的穿刺

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Revista de Senologia y Patologia Mamaria Pub Date : 2025-01-01 DOI: 10.1016/j.senol.2024.100660

Ricardo Pardo Garcia

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Ética y filosofía de la inteligencia artificial aplicada a la enfermedad mamaria 人工智能应用于乳腺疾病的伦理和哲学

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Revista de Senologia y Patologia Mamaria Pub Date : 2024-12-31 DOI: 10.1016/j.senol.2024.100656

David Casacuberta

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Adenomioepitelioma de la mama 乳房腺瘤上皮瘤

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Revista de Senologia y Patologia Mamaria Pub Date : 2024-12-17 DOI: 10.1016/j.senol.2024.100655

Xavier Bargalló , Lledó Cabedo , Esther Sanfeliu , Sergi Ganau , Belén Úbeda , Carla Sitges , Dominika Gasior , Isaac Cebrecos , Eduard Mensión

{"title":"Adenomioepitelioma de la mama","authors":"Xavier Bargalló , Lledó Cabedo , Esther Sanfeliu , Sergi Ganau , Belén Úbeda , Carla Sitges , Dominika Gasior , Isaac Cebrecos , Eduard Mensión","doi":"10.1016/j.senol.2024.100655","DOIUrl":"10.1016/j.senol.2024.100655","url":null,"abstract":"<div><h3>Objectives</h3><div>To perform a descriptive analysis of the clinical information and radiological findings, emphasizing those provided by magnetic resonance imaging of a single-center series of cases of adenomyoepithelioma of the breast.</div></div><div><h3>Material and methods</h3><div>Our series consists of 11 patients, most of them were diagnosed by ultrasound-guided core needle biopsy. In three cases, the initial diagnosis was papilloma, and adenomyoepithelioma was diagnosed by surgical excision or vacuum aspiration biopsy. In five cases, breast magnetic resonance was performed.</div></div><div><h3>Results</h3><div>Most of our cases were diagnosed by mammography from the population-based breast cancer screening program, with a mass or focal asymmetry being the most frequent presentations. Ultrasound show oval and well-defined mass with a tendency to form angles. The two malignant cases showed prominent vessels in the Doppler study. On magnetic resonance imaging, they are predominantly hyperintense on T2 without restriction in diffusion and with intense gadolinium uptake. Three cases (two malignant and one atypical) relapsed.</div></div><div><h3>Conclusion</h3><div>Small adenomyoepitheliomas may mimic fibroadenomas, although they show a certain tendency to show angled edges. Core needle biopsy is usually diagnostic, although it is sometimes difficult to differentiate adenomyoepithelioma from papilloma.</div><div>Magnetic resonance imaging does not help to suspect malignancy since most cases do not show restriction in diffusion. In our series, the presence of vessels in the Doppler study has shown some relation to atypical or malignant adenomyoepithelioma. Wide surgical removal is warranted in atypical or malignant cases.</div></div>","PeriodicalId":38058,"journal":{"name":"Revista de Senologia y Patologia Mamaria","volume":"38 2","pages":"Article 100655"},"PeriodicalIF":0.3,"publicationDate":"2024-12-17","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143141957","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

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