加速癌症诊断:高效组织病理图像分析的新型人工智能管道

IF 0.2 Q4 OBSTETRICS & GYNECOLOGY
David Anglada-Rotger , Sonia Rabanaque-Rodríguez , Laura Sáez-Parés , Jordi Temprana-Salvador
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引用次数: 0

摘要

数字病理学的激增和来自整个幻灯片图像(wsi)的大量数据使得开发能够有效分析和支持癌症诊断的工具变得至关重要。为了应对这一挑战,一种创新的基于人工智能的管道已经开发出来,大大加快了乳腺癌诊断的速度并提高了其准确性。在DigiPatICS项目中,与西班牙加泰罗尼亚的8家医院合作创建了这个管道,首先识别wsi中的组织区域,并将其分解成更小的、可管理的瓷砖。使用智能图像处理技术,它过滤掉不包含相关信息的瓦片,并专注于重要的瓦片。然后,先进的深度学习算法可以识别和分类组织内不同类型的细胞。该系统被证明对HER2、Ki67、ER和PR等关键乳腺癌标志物有效,可以在一夜之间预先计算结果,病理学家只需在工作日选择WSI感兴趣的领域加载预先分析的数据。每个WSI或多或少以1110 s的格式进行分析,在需要时提供可靠的结果。现在,作为常规工作流程的一个组成部分,这种方法正在彻底改变乳腺癌幻灯片的处理方式,增强诊断能力,重塑数字病理学。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
Accelerating cancer diagnostics: A novel AI pipeline for efficient histopathological image analysis
The surge in digital pathology and the vast amount of data from whole slide images (WSIs) have made it essential to develop tools that can efficiently analyze and support cancer diagnosis. An innovative artificial intelligence-based pipeline has been developed to tackle this challenge, significantly speeding up and enhancing the accuracy of breast cancer diagnosis. Created within the DigiPatICS project, in partnership with 8 hospitals across Catalonia, Spain, this pipeline begins by identifying tissue areas in WSIs and breaking them down into smaller, manageable tiles. Using smart image processing techniques, it filters out tiles that do not contain relevant information and focuses on the essential ones. Advanced deep learning algorithms then work to identify and classify different types of cells within the tissue. Proven effective on key breast cancer markers like HER2, Ki67, ER, and PR, the system precomputes the results overnight, allowing pathologists to simply load the pre-analyzed data for the areas of interest of the WSI that they select during their workday. Each WSI is analyzed in more or less 1110 s, providing reliable results that are ready when needed. Now, an integral part of routine workflows, this approach is revolutionizing how breast cancer slides are processed, enhancing diagnostic capabilities, and reshaping digital pathology.
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来源期刊
Revista de Senologia y Patologia Mamaria
Revista de Senologia y Patologia Mamaria Medicine-Obstetrics and Gynecology
CiteScore
0.30
自引率
0.00%
发文量
74
审稿时长
63 days
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