{"title":"An invisible enemy. Echoacousis and aphasia as a rare presentation of a non convulsive status epilepticus. Clinical case","authors":"Yuliia Solodovnikova , Anatoliy Son , Tetiana Marusich , Asel Jusupova","doi":"10.1016/j.ensci.2025.100565","DOIUrl":"10.1016/j.ensci.2025.100565","url":null,"abstract":"<div><div>Status epilepticus is not always an easily recognised condition, which can become a cause of serious consequences, and even death. It can present in two clinical forms: convulsive and nonconvulsive. The clinical symptoms representing nonconvulsive status epilepticus (NCSE) can vary a lot and sometimes be very misleading. We present here a case of a woman, who is a carrier of 6 platinum spirals as a result of endovascular aneurysm embolisation and has undergone a surgery for the removal of the left temporal lobe meningioma. The patient showed the signs of sensorimotor aphasia and echoacusis in the early postoperative period. Taking into account the past history of a tonic-clonic seizure and inability to perform EEG during the clinical manifestations, the diagnosis of NCSE was done clinically, and the treatment started immediately with the IV diazepam and valproic acid administration, leading to complete resolution of aphasia and echoacusis.</div><div>Negative neurological clinical symptoms are rare in the presentation of epilepsy, and echolalia is not yet described as a symptom of a NCSE. In our case the patient presents with the combination of these two symptoms, which can make the diagnosing even more challenging. This case report aims to highlight the variety of clinical symptoms which can represent NCSE and prompt early diagnosis and treatment, avoiding life threatening consequences.</div></div>","PeriodicalId":37974,"journal":{"name":"eNeurologicalSci","volume":"39 ","pages":"Article 100565"},"PeriodicalIF":0.0,"publicationDate":"2025-04-15","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143838428","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
eNeurologicalSciPub Date : 2025-04-15DOI: 10.1016/j.ensci.2025.100566
Kadjo Claude Valery Cedric Aka , Essoin-de Souza Tamia Nancy , Amon-tanoh Muriel , Agbo-Panzo Cedric , Offoumou Fiacre Delors , Aka Arlette Desirée , Baugnan Davide , Toa Bi Axel , Yapo-Ehounoud Constance , Tanoh Christian , Aka-Diarra Evelyne , Assi Berthe
{"title":"Neurophobia among students and interns at the Abidjan Faculty of Medicine (Côte d'Ivoire)","authors":"Kadjo Claude Valery Cedric Aka , Essoin-de Souza Tamia Nancy , Amon-tanoh Muriel , Agbo-Panzo Cedric , Offoumou Fiacre Delors , Aka Arlette Desirée , Baugnan Davide , Toa Bi Axel , Yapo-Ehounoud Constance , Tanoh Christian , Aka-Diarra Evelyne , Assi Berthe","doi":"10.1016/j.ensci.2025.100566","DOIUrl":"10.1016/j.ensci.2025.100566","url":null,"abstract":"<div><h3>Introduction</h3><div>As defined by Jozefowicz in 1994, neurophobia is the fear of neuroscience and clinical neurology. We carried out this study, the first on neurophobia in the Ivory Coast, in order to assess its prevalence among medical students and interns in the Ivorian environment, to identify the factors involved and to propose solutions.</div></div><div><h3>Methodology</h3><div>This was a prospective cross-sectional study carried out during the 2022–2023 academic year at the Abidjan UFR of Medical Sciences. The study population consisted of all students in years 3<sup>ème</sup> to 6<sup>ème</sup> and hospital interns. The Schon questionnaire, transcribed using google form software, was sent to students using the “wathsapp” social network.</div></div><div><h3>Result</h3><div>We obtained 284 responses, i.e. 23 % of all respondents (<em>n</em> = 1228). The sex ratio was 1.65 in favour of men. The subjects considered that they had a level of competence in neurology higher than 6 of the nine specialities selected. These were nephrology, cardiology, rheumatology, endocrinology, psychiatry and geriatrics. Neurology was considered more difficult than cardiology, endocrinology, psychiatry and geriatrics. Subjects' level of knowledge in neurology was rated higher than in nephrology, cardiology, rheumatology, endocrinology, psychiatry and geriatrics. The subjects' level of interest in neurology was higher than in the other specialities. 27.46 % of subjects surveyed were neurophobic.</div></div><div><h3>Conclusion</h3><div>The impact of neurophobia remains harmful to public health, as it is a factor in the sub-optimal management of patients with neurological disorders.</div></div>","PeriodicalId":37974,"journal":{"name":"eNeurologicalSci","volume":"39 ","pages":"Article 100566"},"PeriodicalIF":0.0,"publicationDate":"2025-04-15","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143850439","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
eNeurologicalSciPub Date : 2025-03-14DOI: 10.1016/j.ensci.2025.100563
Patrick Stancu , Nicolae Sanda , Karl-Olof Lovblad , Nils Guinand , Andreas Kleinschmidt , José Bernardo Escribano Paredes
{"title":"Area postrema syndrome as the only sign of medullary infarction adjacent to area postrema","authors":"Patrick Stancu , Nicolae Sanda , Karl-Olof Lovblad , Nils Guinand , Andreas Kleinschmidt , José Bernardo Escribano Paredes","doi":"10.1016/j.ensci.2025.100563","DOIUrl":"10.1016/j.ensci.2025.100563","url":null,"abstract":"<div><div>Area postrema syndrome (APS) is characterized by acute or subacute intractable nausea, vomiting, and/or hiccups lasting for at least 48 h. These symptoms can occur individually or in combination and are typically linked to periventricular brainstem lesions, particularly involving the area postrema (AP). The AP, a highly vascularized circumventricular organ located in the dorsal medulla oblongata, is supplied by the anterior spinal artery and perforating branches of the posterior inferior cerebellar artery (PICA), making it susceptible to pathological processes that can lead to APS. APS rarely occurs in stroke patients, but has been seen with ischemic lesions in the medial brachium pontis. The underlying pathophysiology of APS remains unclear, but remote lesions from the AP suggest involvement of an autonomic network of neuronal structures. This article reports a rare case of APS caused by ischemic stroke near the area postrema, without accompanying neurological impairments. The case highlights the importance of vascular investigation in intractable APS cases, even without focal neurological symptoms, and supports the role of neuronal structures connected to the AP in APS development.</div></div>","PeriodicalId":37974,"journal":{"name":"eNeurologicalSci","volume":"39 ","pages":"Article 100563"},"PeriodicalIF":0.0,"publicationDate":"2025-03-14","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143643029","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
eNeurologicalSciPub Date : 2025-03-01DOI: 10.1016/j.ensci.2025.100557
Kunihisa Miwa
{"title":"Corrigendum to “Oral minocycline therapy as first-line treatment in patients with Myalgic encephalomyelitis and long COVID: A pilot study” [eNeurologicalSci 38 (2025) 100537].","authors":"Kunihisa Miwa","doi":"10.1016/j.ensci.2025.100557","DOIUrl":"10.1016/j.ensci.2025.100557","url":null,"abstract":"","PeriodicalId":37974,"journal":{"name":"eNeurologicalSci","volume":"38 ","pages":"Article 100557"},"PeriodicalIF":0.0,"publicationDate":"2025-03-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143510041","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
eNeurologicalSciPub Date : 2025-03-01DOI: 10.1016/j.ensci.2025.100555
{"title":"Erratum regarding missing conflict of interests statements in previously published articles","authors":"","doi":"10.1016/j.ensci.2025.100555","DOIUrl":"10.1016/j.ensci.2025.100555","url":null,"abstract":"","PeriodicalId":37974,"journal":{"name":"eNeurologicalSci","volume":"38 ","pages":"Article 100555"},"PeriodicalIF":0.0,"publicationDate":"2025-03-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143510039","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
eNeurologicalSciPub Date : 2025-02-17DOI: 10.1016/j.ensci.2025.100561
Lisa Kaindl , Julian Frederic Hotz , Julia Ferrari
{"title":"Cutting-edge stroke prevention strategies","authors":"Lisa Kaindl , Julian Frederic Hotz , Julia Ferrari","doi":"10.1016/j.ensci.2025.100561","DOIUrl":"10.1016/j.ensci.2025.100561","url":null,"abstract":"<div><div>Stroke represents a major public health problem, ranking as a leading cause of death and long-term disability worldwide (1–3). The goal of prevention strategies is to avoid the occurrence of stroke by educating both healthcare professionals and patients about the reduction of risk factors. Despite increasing improvements in acute revascularization therapies, preventive measures remain more effective in decreasing the burden of stroke, as evidenced by the fact that over 75 % of strokes are first events (2). This paper attempts to provide a comprehensive approach by outlining risk factors and new therapeutic approaches. Understanding these is essential for healthcare providers and the general public to develop effective prevention strategies and ultimately reduce the overall incidence of stroke.</div></div>","PeriodicalId":37974,"journal":{"name":"eNeurologicalSci","volume":"39 ","pages":"Article 100561"},"PeriodicalIF":0.0,"publicationDate":"2025-02-17","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143454656","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
eNeurologicalSciPub Date : 2025-02-14DOI: 10.1016/j.ensci.2025.100560
Yacouba Njankouo Mapoure , Elodie Dorothée Ebogo Fouda , Daniel Gams Massi , Caroline Kenmegne , Bertrand Hugo Ngahane Mbatchou
{"title":"Anemia and outcome of patients with ischemic stroke in a referral hospital in Cameroon","authors":"Yacouba Njankouo Mapoure , Elodie Dorothée Ebogo Fouda , Daniel Gams Massi , Caroline Kenmegne , Bertrand Hugo Ngahane Mbatchou","doi":"10.1016/j.ensci.2025.100560","DOIUrl":"10.1016/j.ensci.2025.100560","url":null,"abstract":"<div><h3>Background</h3><div>Stroke and anemia are major public health concerns in Sub-Saharan Africa. However, few data are available on anemia and acute ischemic stroke in our setting.</div></div><div><h3>Purpose</h3><div>To assess the impact of anemia on the outcome of patients with ischemic stroke.</div></div><div><h3>Methods</h3><div>We collected retrospectively data of patients >15 years hospitalized for ischemic stroke at the Douala General Hospital over a period of 9 years, in whom full blood count was done. Anemia was classified as mild, moderate and severe. Multivariate analysis was used to determine predictive factors of poor outcome at 3 months (mortality and poor functional recovery) in ischemic stroke patients with anemia.</div></div><div><h3>Results</h3><div>A total of 691 patients (male, 53.3 %) male were included. Anemia was found in 44.4 % of cases (severe anemia, 10.4 %). Severe anemia was significantly associated with poor functional recovery at 3 months (OR:4.43, 95 %CI:1.02–12.24, <em>p</em> = 0.04). We found no difference in mortality at 3 months between patients with (4.6 %, <em>n</em> = 14) and without (3.9 %, <em>n</em> = 15) anemia (OR:1.48, 95 %CI:0.69–3.14, <em>p</em> = 0.330). Age > 60 years, diastolic blood pressure > 90 mmHg, NIHSS score ≥ 15, and INR > 1.2 were predictive factors of mortality at 3 months in ischemic stroke patients with anemia.</div></div><div><h3>Conclusion</h3><div>Anemia is common in ischemic stroke cases and must be systematically screened.</div></div>","PeriodicalId":37974,"journal":{"name":"eNeurologicalSci","volume":"39 ","pages":"Article 100560"},"PeriodicalIF":0.0,"publicationDate":"2025-02-14","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143444320","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
eNeurologicalSciPub Date : 2025-02-01DOI: 10.1016/j.ensci.2025.100559
Matthew C. Kiernan
{"title":"Recent developments in consensus diagnostic criteria for amyotrophic lateral sclerosis","authors":"Matthew C. Kiernan","doi":"10.1016/j.ensci.2025.100559","DOIUrl":"10.1016/j.ensci.2025.100559","url":null,"abstract":"","PeriodicalId":37974,"journal":{"name":"eNeurologicalSci","volume":"38 ","pages":"Article 100559"},"PeriodicalIF":0.0,"publicationDate":"2025-02-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143146058","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}